Clinical trials: Muscle Disorder
Gastroparesis
A Study to Evaluate Safety, Side Effects, Muscle Activity and Speed of Gastric Emptying of GSK962040
Motilin is a peptide whose action is controlled by motilin receptors located in the gut. Action of Motilin at motilin receptors increases the gastric emptying rate (rate of emptying of food and fluid from the stomach).
- Trial name
- NCT00562848
- Testing
- GSK962040
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Temporo-Myofascial Disorder
Treatment of Temporo-Myofascial Disorder of Muscular Origin Using Botulinum Toxin: A Prospective Study
Temporomandibular disorders (TMD) are a group of conditions involving the temporomandibular joint (TMJ), masticatory muscles and associated structures.
- Trial name
- NCT02810015
- Testing
- Botulinum Toxin Type A
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Diet; Deficiency, Exercise Intervention
Influence of Low Energy Availability on Skeletal Muscle and Cardiovascular Health
The project is designed as a randomized controlled intervention trial in which 60 young trained (n = 30) (Population A) and recreationally active (n = 30) women (Population B) with regular menstruation are divided into four…
- Trial name
- LEA (NCT04821076)
- Testing
- Diet intervention - caloric restriction, Exercise intervention, Diet intervention - Energy balance
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Sarcopenia
Assessing the Efficacy of a Muscle Strength Training Intervention for Sarcopenia in Middle-aged and Elderly Individuals
Taiwan entered an aging society in 2018 and is projected to become a super-aged society by 2025. With the increasing elderly population, age-related diseases have become an urgent issue in modern society.
- Trial name
- NCT07554274
- Testing
- Resistance exercise
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Community-Based Participatory Research, Aged
Associations Between Self-Reported Sleep Duration and Sarcopenia in Community-Dwelling Older Adults
1. BACKGROUNDS: Currently, elderly people comprise more than 10% of the total Taiwanese population. However, within the context of self-reported sleep duration and health risks, research into the association between sleep…
- Conditions
- Community-Based Participatory Research, Aged, Sleep, Body Composition
- Trial name
- NCT02126410
- Where
- Taiwan
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Grip, Muscle Disorder
Investigation of Grip Strength, Pain and Anxiety Levels in Dentists
The aim of the study is to evaluate the relationship between professional experience and grip strength, pain threshold and anxiety level in dentists.
- Conditions
- Grip, Muscle Disorder, Pain, Chronic, Anxiety
- Trial name
- NCT06721117
- Testing
- Grip strength assessment, Forearm muscle strength assessment, Pain threshold assessment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Prehabilitation, Breast Cancer
Prehabilitation With Resistance-exercise Training for Breast Cancer Neoadjuvant Therapy
Breast cancer stands as the foremost cause of cancer-related deaths among women worldwide, with the highest incidence of any cancer type.
- Conditions
- Prehabilitation, Breast Cancer, Postmenopause, Resistance Training
- Trial name
- NEO STRONG (NCT06309290)
- Testing
- Prehabilitation with resistance-exercise training, Usual care program
- Where
- 2 sites in Chile
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Aging, Obesity
Resistance Exercise Training in the Older Population With Obesity
Background: Aging leads to an alteration in the immune response, characterized by a chronic inflammatory state, and a progressive decrease in muscle quantity and quality, a situation that increases in women and in the presence of…
- Trial name
- RETOPO (NCT06367296)
- Testing
- Prolonged resistance exercise training
- Where
- 2 sites in Chile
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Aging, Sarcopenia
Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Adults
This study will evaluate the adaptations in skeletal muscle that occur in response to 10 weeks of weight training with or without peanut protein supplementation in older adult men and women.
- Trial name
- NCT04015479
- Testing
- Peanut Protein Powder, Full body resistance training
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Auburn University
Stroke
Importance of Core Stability for Coordinated Movement of the Human Body in Stroke Rehabilitation
This is an observational study. Measurements were made during two different motor tasks: trunk tilts without and with the tension of the abdominal muscles in the sitting position and walking in a place with high knee lifting.
- Trial name
- NCT04886466
- Testing
- core stability in a sitting position and while walking in one place
- Where
- Poland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Anna Olczak
Asthma
Airway Smooth Muscle and Asthma Severity
Our hypothesis is that the severity of asthma is determined by the way in which airway smooth muscle cells grow and release inflammatory mediators.
- Trial name
- NCT00779870
- Testing
- bronchoscopy
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Colorectal Cancer, Exercise, Aerobic
Pedaling at a Low-Moderate Intensity During Chemotherapy Administration
The purpose of this study is to evaluate the feasibility of completing a low-moderate intensity pedaling session concurrent to chemotherapy treatment for colorectal cancer.
- Conditions
- Colorectal Cancer, Exercise, Aerobic, Chemotherapy, Chemotherapeutic Toxicity
- Trial name
- NCT04258969
- Testing
- Pedaling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Dysphagia, Fecal Incontinence
Evaluation of Potential Vitamin D Effects on Muscle: a Pilot Study
People who do not have adequate amounts of vitamin D develop weakness of leg and arm muscles. This study will determine if vitamin D supplementation benefits muscle functions important for swallowing, bladder and bowel function.
- Conditions
- Dysphagia, Fecal Incontinence, Urinary Incontinence
- Trial name
- NCT00593996
- Testing
- Ergocalciferol (vitamin D2)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Delayed-onset Muscle Soreness, Sleep
Sleep and Delayed-onset Muscle Soreness
There is a need for further experimental research in order to gain a more in-depth understanding of this vicious cycle of pain and sleep disorders.
- Conditions
- Delayed-onset Muscle Soreness, Sleep, Pain
- Trial name
- NCT06699186
- Testing
- Sleep, Non-sleep
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Fibromyalgia, Pain, Chronic
Psychobiological Mechanisms Underlying Chronic Pain
Pain is a powerful motivator of behavior and it is more than the perception of nociceptive input. It is a complex experience that comprises different components: sensory discriminative, emotional-motivational and cognitive…
- Conditions
- Fibromyalgia, Pain, Chronic, Chronic Pain, Widespread
- Trial name
- NCT04674670
- Testing
- Bromocriptine Mesylate Capsules, Amisulpride 400 MG
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- susanne becker
Musculoskeletal Pain, Musculoskeletal Strain
Surgeon Ergonomics in Robotic-assisted Laparoscopic Vs Standard Laparoscopic Surgery
Musculoskeletal injuries amongst surgeons are prevalent. This project will determine whether Robotic-assisted Laparoscopic surgery (RALS) offers superior benefits to surgeon's musculoskeletal health than standard laparoscopic…
- Conditions
- Musculoskeletal Pain, Musculoskeletal Strain, Fatigue; Muscle, Heart, Cognitive Impairment
- Trial name
- MURALS (NCT04477746)
- Where
- 2 sites in United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Muscle Soreness
A Study to Evaluate the Analgesic Properties of Topically Applied Menthol in Marathon Participants
The purpose of the research study is to better understand the factors that impact pain experience in adult (18+ years) marathon runners participating in the 2026 Chicago Marathon and to better understand if topically applied…
- Trial name
- NCT07873242
- Testing
- Observational, Non-Interventional Study
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Work-Related Condition, Musculoskeletal Health
Relationship Between Neck Posture and Stiffness of Head and Neck Muscles, Pain and Proprioception in Desk Workers
In our study, posture in desk workers; it aims to evaluate the relationship between cervical range of motion, proprioception, muscle stiffness, posture and pain.
- Trial name
- NCT06012773
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pınar Kuyulu
Dental Pain, Muscle Sensitivity to Pressure
Analgetic Effect of Nitrousoxide-oxygen Inhalation for Dental Treatment of Children
To assess the analgetic effect of nitrousoxide-oxygen inhalation on pain perception in 12-15 years old children from 1) the dental pulp; 2) the masseter muscle; 3) the skin on the upper lip
- Conditions
- Dental Pain, Muscle Sensitivity to Pressure, Skin Sensitivity to Electric Stimulation
- Trial name
- NCT01022294
- Testing
- Nitrousoxide-oxygen and atmospheric air, Atmospheric air; nitrousoxide-oxygen
- Where
- Denmark
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Fractures in Children, Apophysitis
Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football
A total genotype risk score was generated based on the findings of previous research for non-contact injury, non-contact muscle injury, tendon injury, ligament injury, fracture injury and apophysitis injury.
- Conditions
- Fractures in Children, Apophysitis, Muscle Strain, Ligament Injury
- Trial name
- NCT05220969
- Testing
- Total Genotype Risk Score
- Where
- 2 sites in United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- St Mary's University College