Clinical trials: Muscle Disorders
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Cardiovascular Analysis of PEM
The purpose of this study is to examine cardiopulmonary function in Chronic Fatigue Syndrome (CFS) patients and determine how it relates to the common symptom of Post-exertional malaise (PEM).
- Trial name
- NCT04740736
- Testing
- Saline Infusion
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Sarcopenia
Cause and Importance of the Age-dependent Sarcopenia
The goal of this cross-sectional study is to evaluate the difference in cytokine profiling approach and mitochondrial function between geriatric sarcopenic patients (group 1) and geriatric non-sarcopenic patients (group 2) and…
- Trial name
- SARCOPENIA (NCT02994901)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Weight Loss, Muscle Loss
Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency
Military personnel face many physiological challenges, including sustained physical activity and prolonged periods of negative energy balance.
- Conditions
- Weight Loss, Muscle Loss, Bone Loss
- Trial name
- NCT01292395
- Testing
- Dietary Protein Intake
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
COPD (Chronic Obstructive Pulmonary Disease)
Comparison of Clinical Parameters in Chronic Obstructive Pulmonary Disease Patients and Healthy Individuals
The investigators think that the functions of core stabilization muscles are different in chronic obstructive pulmonary disease (COPD) patients than in healthy individuals.
- Trial name
- NCT06677671
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Sarcopenia, High Blood Pressure
The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia
Current prevention and treatment of high blood pressure (BP) in sarcopenia, by non-pharmacological approaches remain limited and are far from optimal.
- Conditions
- Sarcopenia, High Blood Pressure, Hypertension
- Trial name
- INERTIA (NCT04255745)
- Testing
- progressive resistance training
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Sarcopenia
Evaluation of Sarcopenia in Women in Different Stages of Life and in Hormonal Therapy or Not
The three-year interventional study has the following objectives: The study aims to assess the prevalence of sarcopenia in menopausal women receiving hormone replacement therapy or not compared with pre-menopausal women.
- Trial name
- NCT06792201
- Testing
- SARC-F, Handgrip test, Chair stand test
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hydroxymethylglutaryl-CoA Reductase Inhibitors, Myopathy
Muscle Characteristics Associated With Statin Therapy
The purpose of this study is to investigate the mechanism of statin-related myopathy by evaluating muscle samples before and after statin exposure.
- Trial name
- NCT00990834
- Testing
- simvastatin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Scripps Health
Polymyalgia Rheumatica
Etanercept Treatment in the Early Course of Polymyalgia Rheumatica
The purpose of this study is to evaluate the effect of the tumor necrosis factor alpha (TNF) antagonist, etanercept, on the early clinical course of polymyalgia rheumatica (PMR).
- Trial name
- NCT00524381
- Testing
- Etanercept (Enbrel)
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Fibromyalgia
FIbromyalgia anD GenetIcs Subgroups (FIDGIS)
Fibromyalgia syndrome (FS) is characterized by widespread pain and affect 0.5 to 5 % of the general population, with a higher prevalence in women.
- Trial name
- FIDGIS (NCT04624581)
- Testing
- Electrophysiological measurement of reflex nociceptive flexion threshold (RIII reflex) using Nicolet Vicking device
- Where
- France
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Hydroxymethylglutaryl-CoA Reductase Inhibitors, Hypercholesterolemia
A Tool to Help Patients With Muscle Symptoms After Taking a Statin Medication.
The goal of this clinical trial is to learn if an educational website can help patients make an informed decision and engage in shared decision-making with their healthcare provider regarding cholesterol lowering medication use…
- Conditions
- Hydroxymethylglutaryl-CoA Reductase Inhibitors, Hypercholesterolemia, Cardiovascular Diseases, Pharmacists
- Trial name
- 1821534-10 (NCT06423365)
- Testing
- Virtual Statin Management (VSM)
- Where
- United States
- Volunteers
- 898 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sickle Cell Disease
Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease
Background : Sickle cell patients have profound remodeling of their muscle microcirculation networks with signs of amyotrophy. However, the consequences of these muscle alterations on the functional status of muscles are unknown.
- Trial name
- DREPAMUSCLE (NCT03243812)
- Testing
- Blood sampling, Maximum Voluntary Contraction (MVC) test force, Localized muscle endurance test
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Neuromuscular Diseases
Effects of Pre-event Massage Over the Neuromuscular Response
The study observes the effect of a pre-event massage on the gastrocnemius muscles over the neuromuscular response of the gastrocnemious muscles.
- Trial name
- NCT03941067
- Testing
- Pre-event massage
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Irritable Bowel, Fibromyalgia
Psychiatric Disorders and Functional Somatic Disorders
The objectives of this study are: Firstly, to investigate the association between psychiatric disorders and functional somatic disorder (FSD).
- Conditions
- Irritable Bowel, Fibromyalgia, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT06006715
- Volunteers
- 7,493 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Facio-Scapulo-Humeral Dystrophy
Computerized Facial Recognition for Automated Diagnosis of the Facio-Scapulo-Humeral Muscular Dystrophy (FSMHD)
The clinical diagnosis of Facio-Scapulo-Humeral Muscular Dystrophy (FSHMD) requires the movement of patients to a medical centre and a lengthy examination involving medical personnel, and may be underestimated in the most…
- Trial name
- CV4DIAGNOSIS (NCT04377217)
- Testing
- Video recording
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Shoulder Impingement Syndrome
Electromyographic Activity of Posterior Oblique Sling Muscles in Patients With Shoulder Impingement Syndrome
this study aims to assess the gluteus maximus muscle electromyographic activity and the latissimus dorsi muscle electromyographic activity in patients with shoulder impingement syndrome , to improve the assessment procedure and…
- Trial name
- EMG (NCT06789991)
- Testing
- electromyography
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sarcopenia, Chronic Lower Back Pain
Prevalence and Factors Associated With Sarcopenia in Pre-retirement Aged Adults With Chronic Non-specific Lower Back Pain
To study the prevalence of sarcopenia in a pre-retirement group with chronic lower back pain and factors associated between sarcopenia and chronic lower back pain in the pre-retirement group.
- Trial name
- NCT05894213
- Where
- Thailand
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Trigger Point Pain, Myofascial
Comparison of High Power Pain Threshold Ultrasound and Ischemic Compression Techniques for Treatment of Trigger Points
This study aimed to compare the efficacy of ischemic compression and two different application methods of high power pain threshold ultrasound techniques on latent trigger point treatment.
- Trial name
- NCT04823013
- Testing
- high power pain threshold ultrasound which the dose was kept constant, high power pain threshold ultrasound which the dose reduced to one half, ischemic compression
- Where
- Turkey (Türkiye)
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Gazi University
Fatigue
Role of Artificial Intelligence in Predicting Muscle Fatigue Using Virtual Reality Training
The goal of this observational predicted study is to predict muscle fatigue using a specific AI algorithm in healthy vs post Covid-19 infected individuals.
- Trial name
- NCT05813613
- Testing
- Squatting with the aid of Kynapsis Virtual Training apparatus.
- Where
- Lebanon
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beirut Arab University
Flat Feet, Lower-Limb Muscle Activation
Plantar Stimulation, Whole-Body Vibration, and Baduanjin for Muscle Activation
This study will examine how different short-term exercise and vibration conditions affect lower-limb muscle activity in young adults with flat feet and young adults with normal feet.
- Conditions
- Flat Feet, Lower-Limb Muscle Activation, Neuromuscular Response
- Trial name
- NCT07811674
- Testing
- Whole-body Vibration Training,Whole-Body Vibration With Regional Plantar Stimulation,Baduanjin
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Sarcopenia
Dietary Supplements and Aging Muscle
The purpose of this study is to determine whether older adults (ages 65-89) who consume the dietary supplement Juven (Abbott Laboratories) versus placebo for 6 months will demonstrate increases in fat-free mass, muscle volume,and…
- Trial name
- NCT01057082
- Testing
- Juven
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
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