Clinical trials: Muscle Disorders
Fibromyalgia, Autonomic Dysfunction
Association Between Autonomic Dysfunction and Choroidal Vascularity Index in Fibromyalgia
Fibromyalgia is frequently accompanied by autonomic nervous system dysfunction, often characterized by sympathetic predominance.
- Trial name
- NCT07345546
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Low Back Pain, Mechanical, Piriformis Syndrome
Strain-Counterstrain Treatment of Piriformis Pain
The purpose of this investigator-initiated study is to provide an efficient and non-invasive treatment option for pain caused by the piriformis muscle.
- Conditions
- Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
- Trial name
- NCT05023005
- Testing
- Strain-Counterstrain treatment of piriformis muscle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Congenital Adrenal Hyperplasia, Exercise Capacity
Exercise Capacity, Physical Fitness, and Physical Activity Levels in Children With CAH
Congenital Adrenal Hyperplesia (CAH) is a group of automosal recessive disorders that develop due to a deficiency of one of the five enyzmes necessary for cortisol synthesis in the adrenal cortex.
- Conditions
- Congenital Adrenal Hyperplasia, Exercise Capacity, Physical Activity, Quality of Life
- Trial name
- NCT06449456
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Rheumatoid Arthritis (RA)
The Effects of Kinesiophobia and Proprioception on Disability and Function in Rheumatoid Hand
This is a cross-sectional study aimed at examining the effects of kinesiophobia and proprioception on disability and function in the rheumatoid hand, compared to healthy controls.
- Trial name
- NCT07141927
- Testing
- Measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Carpal Tunnel Syndrome, Trigger Finger
Wound Closure Study in Carpal Tunnel and Trigger Finger Surgery
Does a difference in patient satisfaction and cosmetic outcome exist between wound closure with absorbable or non-absorbable sutures.
- Trial name
- NCT03781141
- Testing
- Wound closure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Fibromyalgia, Secondary
Work-Related Fibromyalgia
The research is about fibromyalgia prevalency in working population and searching work-related fibromyalgia.
- Trial name
- NCT03535454
- Testing
- working hours
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Healthy Volunteer, Muscular Dystrophies
Absorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers
This is a Phase 1 2-part, single-center, open-label study in healthy male volunteers. Part A will assess the absorption, metabolism, excretion, and pharmacokinetics of one oral dose of radiolabeled EDG-5506.
- Conditions
- Healthy Volunteer, Muscular Dystrophies, Muscular Disorders, Atrophic, Muscular Diseases
- Trial name
- NCT05730842
- Testing
- EDG-5506 Tablet, Radiolabeled EDG-5506 Suspension, Radiolabeled EDG-5506 Intravenous
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Edgewise Therapeutics, Inc.
Lipedema, Obesity & Overweight
Ultrasonographic Evaluation and Pedobarographic Correlation of Lower Extremity Muscles in Lipedema Patients
The primary aim of this study is to evaluate the lower extremity muscle structure, lower extremity alignment, and foot posture in lipedema; secondly, to reveal the chain relationship and biomechanical problems that may be…
- Trial name
- PODUSG (NCT07724483)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Urinary Incontinence
Effects of Paula Exercises and Tibial Nerve Stimulation in Stress Urinary Incontinence
The aim of this study is to compare the combined effects of Paula method \& tibial nerve stimulation on incontinence, pelvic floor muscles strength, sexual function and quality of life in stress urinary incontinence
- Trial name
- NCT07576205
- Testing
- Paula Exercises, Tibial Nerve Stimulation
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Vegan Diet, Sarcopenia
The Effect of a 12-week Self-composed Vegan Diet With or Without Concurrent Resistance Exercise on Thigh Muscle Volume in Older Adults
Consumers are increasingly encouraged to consume more plant-based foods and lower their consumption of foods from animal origin. This shift is driven by environmental and health factors.
- Conditions
- Vegan Diet, Sarcopenia, Cardiovascular Health, Osteoporosis
- Trial name
- Vold (NCT05809466)
- Testing
- Vegan diet, Resistance exercise, Omnivorous diet
- Where
- Netherlands
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Temporomandibular Joint Disorders
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection
Dysfunction of the jaw, associated with pain in the jaw or about the jaw in the face can be quite long lasting and debilitating.
- Trial name
- NCT01617356
- Testing
- Injection of 20% dextrose/ 0.2% lidocaine, Injection of 1 ml of 0.8 SW/0.2% lidocaine
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Frusso, Ricardo, M.D.
Stroke
Reliability and Validity Study for SWE of Shoulder Muscles in Persons After Stroke.
This study aims 1. To examine the reliability of SWE assessment in the shoulder muscles of persons after a stroke. 2. To assess if differentiation can be made between the hemiplegic (HP) and non-hemiplegic (NHP) side and between…
- Trial name
- SWE_stroke (NCT04581551)
- Testing
- SWE assessor 1, SWE assessor 2, Stretch intervention
- Where
- 2 sites in Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Piriformis Muscle Syndrome, Anthropometry
Pelvic and Hip Morphometry in Piriformis Syndrome
In this case-control study, 23 patients diagnosed as PS by diagnostic injection with ultrasound guidance were selected as the study group.
- Trial name
- NCT04600024
- Testing
- Ultrasound guided diagnostic injection
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Neurodegenerative Disorders
Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases
Human fibroblasts and possibly other human somatic cells may be reprogrammed into induced pluripotent stem (iPS) cells by the forced expression of transcription factors (1-5).
- Trial name
- NCT00874783
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Synkinesis
Botox Injections in Non-Cranial Nerve VII Innervated Muscles for Facial Synkinesis
Facial synkinesis is a condition that occurs following facial nerve (CN7) injury, typically secondary to Bell's palsy, trauma, surgery (e.g., acoustic neuroma resection), or malignancy.
- Trial name
- NCT07295288
- Testing
- Botulinum Toxin Type A Injection [Botox]
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Osteoporosis, Osteopenia
Serum Myostatin and Irisin Levels in Postmenopausal Women: Association With Bone Mineral Density and Muscle Strength
This study aims to evaluate the relationship between serum myostatin and irisin levels and bone mineral density and muscle strength in postmenopausal women.
- Trial name
- MYOIRISIN (NCT07519551)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Fibromyalgia, Psoriatic Arthritis
Quantitative Ultrasound of the Enthesis in Fibromyalgia and Psoriatic Arthritis
This prospective, cross-sectional, observational study will include subjects with fibromyalgia (FM), psoriatic arthritis (PsA) and asymptomatic controls.
- Trial name
- NCT05447741
- Testing
- Quantitative Ultrasound
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Sarcopenia
Creatine Supplementation During GLP-1a Therapy
GLP-1 receptor agonists are effective for weight loss, but significant muscle mass is lost as a proportion of this weight loss. This study combines resistance-training and creatine supplementation to try to prevent this loss of…
- Trial name
- NCT07625202
- Testing
- Dietary supplementation during a 12 week resistance-training program (creatine)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Menorrhagia, Dysfunctional Uterine Bleeding
Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution
Approximately 600,000 women undergo hysterectomy each year in the United States, of which 12% are laparoscopic. The most common indications for hysterectomy are: symptomatic uterine leiomyomas (40.7%), endometriosis (17.7%), and…
- Conditions
- Menorrhagia, Dysfunctional Uterine Bleeding, Leiomyoma, Pelvic Pain
- Trial name
- NCT01581905
- Testing
- Conventional Laparoscopic Hysterectomy (LH), Robot Assisted Hysterectomy
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Duchenne Muscular Dystrophy (DMD)
To Compare the Pharmacokinetics Profiles of ISO 20, IBU 200 and IBU Plus ISO Combinations 200 + 20
This study will evaluate the pharmacokinetics plasma profile of 3 treatments: ISO 20, IBU 200 and IBU and ISO combinations (200 +20) given in single dose.
- Trial name
- ISOFEN1 (NCT01478022)
- Testing
- Isosorbide Dinitrate, Ibuprofen, Ibuprofen and Isosorbide Dinitrate combination
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Parent Project, Italy
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