Clinical trials: Muscle Disorders
Ulnar Collateral Ligament Sprain, Tibialis Posterior Dysfunction
Validating the Speckle Tracking Methods on Soft Tissue Strain, Displacement, and Roles in Physical Therapy
This three-year research project aims to test the hypothesis that strain and displacement characteristics of human soft tissues are influenced by (1) habitual physical activity, (2) functional impairment, and (3) training…
- Conditions
- Ulnar Collateral Ligament Sprain, Tibialis Posterior Dysfunction, Anterior Cruciate Ligament Reconstruction Rehabilitation, Ultrasound Evaluation
- Trial name
- NCT07485530
- Testing
- blood flow restriction training, nordic exercise training
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Metabolism and Nutrition Disorder, Metabolic Disturbance
Markers of Carnitine Acetyltransferase (CrAT) Protein Activity and Carnitine Availability
This study aims to measure skeletal muscle metabolism in vivo during exercise using the non-invasive Magnetic Resonance Spectroscopy (MRS) technique.
- Trial name
- NCT03697928
- Testing
- Exercise metabolism
- Where
- Netherlands
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Muscular Diseases
The Role of Ischaemia-reperfusion Injury in the Pathogenesis of Muscle Wasting After Thoracic Aortic Surgery
Single-centre observational study over one year investigating the mechanisms of muscle homeostasis in patients with acute skeletal muscle atrophy following major aortic surgery
- Trial name
- RIMMAS (NCT03354767)
- Testing
- Aortic and aortic valve surgery
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Temporomandibular Joint Dysfunction Syndrome
Manual Therapy and Exercises Applied to Cervical Spine in Patients With Temporomandibular Disorders
The objective of this study was to investigate the effect of a manual therapy and exercise program, focused on the rehabilitation of cervical function, on clinical signs and mandibular function in subjects with TMD.
- Trial name
- NCT01954511
- Testing
- Manual therapy, Pressure biofeedback device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Compartment Syndrome of Leg
Early Diagnosis of Compartment Syndrome by Multimodal Detection Technique
compartment syndrome has a high incidence in patients with a variety of diseases, including fractures, and delayed diagnosis or without intervention can lead to severe adverse prognosis, such as limb deformities, amputations and…
- Trial name
- MMCS (NCT04442672)
- Testing
- acute compartment syndrome model of health volunteer
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Muscle Atrophy, Muscle Disuse Atrophy
n3 PUFA and Muscle-disuse Atrophy in Older Women
This study will examine the influence of n3 PUFA supplementation on the rate of muscle atrophy in older women undergoing 1 week of unilateral limb immobilization.
- Conditions
- Muscle Atrophy, Muscle Disuse Atrophy, Sarcopenia
- Trial name
- NCT03808519
- Testing
- n3 PUFA-enriched fish oil
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- McMaster University
Aging, Healthy Aging
Eating Habits and Lifestyle Profile of an Italian Aging Cohort
Aging is characterized by low-grade inflammatory state, supported by impairment oxidative balance and endocrine changes, leading to changes in: body composition, such as decrease in lean body mass and increase in adipose tissue…
- Conditions
- Aging, Healthy Aging, Life Style, Eating Habit
- Trial name
- NCT04401930
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Chronic Fatigue Syndrome
Exertional Exhaustion in Chronic Fatigue Syndrome
Post-exertional malaise was modeled by having Chronic Fatigue Syndrome (CFS) and sedentary control subjects perform submaximal exercise on 2 consecutive days with objective changes in brain function measured by magnetic resonance…
- Trial name
- NCT03567811
- Testing
- Submaximal bicycle exercise stress test on Days 1 and 2
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Chronic Obstructive Pulmonary Disease
Evaluation in Individuals with COPD and Asymptomatic Individuals
The literature does not provide sufficient information on the evaluation of frailty, handgrip strength, physical activity, kinesiophobia, and fatigue in elderly individuals with Chronic Obstructive Pulmonary Disease and…
- Trial name
- NCT06077357
- Testing
- MMSE Test, PASE Test, The PRISMA-7 Frailty Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Sickle Cell Disease
Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease
Background : Sickle cell patients have profound remodeling of their muscle microcirculation networks with signs of amyotrophy. However, the consequences of these muscle alterations on the functional status of muscles are unknown.
- Trial name
- DREPAMUSCLE (NCT03243812)
- Testing
- Blood sampling, Maximum Voluntary Contraction (MVC) test force, Localized muscle endurance test
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
TMJ Disorders, MRI Scans
TMJ Fibrocartilage Detection Using MRI
Objective: The aims of this study will be to detect the fibrocartilage layer (FC) of the human temporomandibular joint (TMJ) using 3D SPGR (Spoiled GRASS sequence) (T1 WATS) sequence and to compare these results with those of…
- Trial name
- WATS (NCT03891511)
- Testing
- MRI scann
- Where
- Chile
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Elderly, Sarcopenia
Effect of Protein Consumption and Resistance Training on Body Composition, Muscular Strength and Functional Capacity in the Elderly
The increase in life expectancy of the world population is associated with a higher incidence of diseases, leading to functional incapacity and dependence in old age.
- Trial name
- NCT03862937
- Testing
- Exercise training + whey protein
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Inactivity, Physical, Aging
Impact of Postprandial 'Exercise Snacks' on Protein and Glucose Metabolism Following a Period of Step Reduction in Older Adults
The purpose of this study is to assess the impact of 3-days reduced physical activity (<1500 steps/day) with/without 'exercise snacks' (15 chair stands with calf raises every 30 min) on skeletal muscle metabolic health.
- Conditions
- Inactivity, Physical, Aging, Healthy Aging, Sarcopenia
- Trial name
- NCT05810272
- Testing
- Metabolic Trial, 15 sit-to-stands with calf raises
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Lumbar Disc Herniation, Lumbar Disc Disease
Effects of Kinesio Taping on Pain, Endurance, Proprioception, Mobility and Disability in Lumbar Disc Herniation
In addition to the physical therapy program, taping was applied to 90 patients diagnosed with lumbar disc herniation. 90 patients were randomized into 3 groups.
- Conditions
- Lumbar Disc Herniation, Lumbar Disc Disease, Chronic Pain
- Trial name
- NCT06777095
- Testing
- Routine Treatment + I Taping, Routine Treatment + Star Taping, Routine Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sevtap Günay
Dementia, Gait
Fine and Gross Motor Function and Relationship With Muscle Tone in Older Adults With and Without Dementia
The purpose of this study was (1) to investigate changes in gait, balance, fine motor function, and muscle tone, and (2) to find out if there is a correlation between muscle tone/presence of paratonia and motor function (gross…
- Conditions
- Dementia, Gait, Balance, Muscle Tone
- Trial name
- NCT03479567
- Testing
- Gait accelerometry, balance accelerometry, Fine motor skill test
- Where
- Belgium
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University Ghent
Ergonomics
Effect of Postural Correction Exercises on Shoulder Muscles Tenderness and Performance in Subjects Addicting Smartphones
smartphones have replaced most of the keypad phone products due to their small size and easy of portability. As a result, smartphone users experience an increase in musculoskeletal problems in the neck and shoulder.
- Trial name
- NCT05305807
- Testing
- Postural exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Congenital Adrenal Hyperplasia, Exercise Capacity
Exercise Capacity, Physical Fitness, and Physical Activity Levels in Children With CAH
Congenital Adrenal Hyperplesia (CAH) is a group of automosal recessive disorders that develop due to a deficiency of one of the five enyzmes necessary for cortisol synthesis in the adrenal cortex.
- Conditions
- Congenital Adrenal Hyperplasia, Exercise Capacity, Physical Activity, Quality of Life
- Trial name
- NCT06449456
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Temporomandibular Joint Dysfunction, Myofascial Pain
Effectiveness of Telerehabilitation in Individuals With Temporomandibular Joint Dysfunction and Myofascial Pain
Telerehabilitation is a treatment method that allows the patient to access treatment remotely, regardless of where they are, thanks to developing technology.
- Trial name
- NCT06526845
- Testing
- Video-Conference based rehabilitation, Home-Based rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Biruni University
Fibromyalgia, Neck Pain Musculoskeletal
VALIDITY AND RELIABILITY OF THE TURKISH VERSION OF THE SEX PAIN QUESTIONNAIRE
Although there are many questionnaires used in the literature regarding sexual function and satisfaction, these questionnaires evaluate sexual problems regardless of the chronic pain condition and have not been validated for…
- Conditions
- Fibromyalgia, Neck Pain Musculoskeletal, Back Pain Lower Back Chronic, Musculoskeletal Diseases
- Trial name
- SPQ (NCT07536672)
- Testing
- surveys
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Muscle Weakness
Effects Resistance Training on Motor Control and Cognition
It is well documented that both balance and resistance training have the potential to mitigate intrinsic fall risk factors in older adults.
- Trial name
- KFPS_2 (NCT03017365)
- Testing
- Stable Resistance Training, Unstable Resistance Training, Adductor/Abductor Resistance Training
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Kassel
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