Clinical trials: Muscle Disorders
Insulin Resistance
Ceramides in Muscle During Insulin Resistance
Overnutrition and physical inactivity promote the accumulation of sphingolipids such as ceramides which block insulin signaling and anabolic metabolism.
- Trial name
- NCT03731598
- Testing
- bed rest
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Psychotic Disorder, SCHIZOPHRENIA 1 (Disorder)
Ultrasound Assessment of Gluteal Muscle in Patients Receiving Depot Antipsychotics and Healthy Volunteers
This observational study will use ultrasound to assess the gluteal musculature in patients receiving depot antipsychotic medication and in healthy volunteers.
- Conditions
- Psychotic Disorder, SCHIZOPHRENIA 1 (Disorder), Intramuscular Injection
- Trial name
- ULPSYK (NCT07815587)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Uterine Fibroids, Osteoporosis
Women's Use of Alternative Medicine: A Multiethnic Study
The purpose of this study is to examine socio-cultural factors of women's use of complementary and alternative medicine (CAM). The effects of socioeconomic status, social networks and acculturation on CAM use will be assessed…
- Conditions
- Uterine Fibroids, Osteoporosis, Urinary Tract Infection, High Blood Pressure
- Trial name
- NCT00067249
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Joint Discomfort, Musculoskeletal Pain
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of resO™ Bone and Joint Support Postbiotic on Physical Function, Pain Interference, and Mobility in Adults With Joint Discomfort
This randomized, double-blind, placebo-controlled study evaluates the effects of resO™ Bone and Joint Support Postbiotic on physical function, pain interference, mobility, and recovery in adults aged 18-75 years experiencing…
- Conditions
- Joint Discomfort, Musculoskeletal Pain, Mobility Limitation
- Trial name
- RESO101 (NCT07602426)
- Testing
- Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Able Biolabs, LLC
Low Back Pain, Muscle Weakness
NASM OPT for Gluteal Enhancement in Non-Athletic Women: An RCT
This RCT evaluates a 12-week NASM OPT program targeting gluteal muscle strength, hip aesthetics (shape, lift, circumference), and low back pain in 120 non-athletic women.
- Conditions
- Low Back Pain, Muscle Weakness, Body Image Disturbance
- Trial name
- GlutealEnhan (NCT06977958)
- Testing
- NASM OPT Group, General Exercise Group
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Inadequate or Impaired Respiratory Function
Positive Airway Pressure Versus Breathing Exercises With Load Inspiratory in Patients Undergoing Bariatric Surgery
Obesity, due to excess fat in the thoracoabdominal region, can promote changes in respiratory function and lung function, leading to reduction in lung volume and capacity.
- Trial name
- NCT02682771
- Testing
- Bilevel positive airway pressure, PowerBreathe, Conventional Respiratory Physiotherapy (CRP)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Metabolic Syndrome
Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome
The primary objective of this study is to examine whether exercise training alone, liraglutide treatment alone or exercise training plus liraglutide treatment increases cardiac and skeletal muscle microvascular blood volume…
- Trial name
- ZQL008 (NCT04575844)
- Testing
- Liraglutide, Exercise training, Liraglutide + Exercise training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Type 2 Diabetes Mellitus
Effect of AT-derived miRNA on the Biology and Insulin Sensitivity of Skeletal Muscle in Humans
The purpose of this study is examine the effect of fat tissue-released miRNA on skeletal muscle and if abnormal fat tissue-released miRNA contributes to insulin resistance in obese individuals.
- Trial name
- miRNA (NCT02459106)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Musculoskeletal Pain
Test-Retest Reliability of an Experimental Model of Shoulder Muscle Pain
High frequency oscillations of non-ionizing electromagnetic fields range can heat deep tissues in a well-localized region. Recently, a new SWD-based model showed to be a promising tool for investigating muscle pain in humans.
- Trial name
- NCT05412316
- Testing
- Intervention: Short-wave diathermy
- Where
- Argentina
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Foot Diseases
The Effectiveness of a Protocol for Muscular Foot Strengthening On a Capacity to Control the Deformation of the DOT Plantar Medial
The human foot allows to perform several functions, rather than providing a Static support for the body, the foot acts dynamically in walking and Movement of the body, requiring adequate biomechanics responsible for Maintenance…
- Trial name
- NCT03117244
- Testing
- Exercise for Foot Strengthening, Exercise for Foot Strengthening and Electrostimulation
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Chronic Obstructive Pulmonary Disease
Fibre Specific Signalling in the Locomotor Myopathy of Chronic Obstructive Pulmonary Disease
Skeletal muscle is composed of two fibre types which are intertwined. Skeletal muscle weakness, particularly of the walking muscles, is an important complication of Chronic Obstructive Pulmonary Disease (COPD) but so far the…
- Trial name
- NCT01471587
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Disuse Atrophy
The Efficacy of Protein Supplementation on Attenuating Muscle Atrophy Following Disuse in the Collegiate Population
Following orthopedic surgery and/or injury, a significant loss of muscle mass is generally observed. While this loss of muscle mass appears to be the norm, it causes significant problems in both the athletic and general…
- Trial name
- NCT03454347
- Testing
- Profile Perform, Lower Limb Suspension
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Sarcopenia
Investigating Loss of Neuromuscular Junction Transmission Fidelity in Older Adults
Sarcopenia is a condition characterised by age-related loss of muscle mass and function. Factors affecting the strength of muscle contraction independent of mass, such as neuromuscular junction (NMJ) transmission, are…
- Trial name
- STAMINA (NCT04904926)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- NMD Pharma A/S
Muscular Dystrophies, Myopathies
Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular Diseases
This study has the general objective of observing walking parameters during a clinical test to objectively estimate fatigue in patients with neuromuscular diseases.
- Conditions
- Muscular Dystrophies, Myopathies, Spinal Muscular Atrophy (SMA), Charcot Marie Tooth Disease
- Trial name
- NCT06666816
- Testing
- inapplicable
- Where
- 2 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Sleep Bruxism, Adult
Clinical Condition and Sleep Quality Factors Associated With Sleep Bruxism in Adults.
This cross-sectional study will evaluate the association between sociodemographic, occupational, clinical conditions, psychological (sense of coherence), sleep quality variables and SB diagnosed by PSG, the gold standard exam…
- Trial name
- NCT04015349
- Testing
- Polysomnography
- Where
- Brazil
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Muscle Weakness Condition
A Study to Analyse the Immediate Effect of Dry Needling and Extra Corporeal Shock Wave Therapy on Hand Grip Strength
An argument to analyse the Immediate effect of dry needling or extra corporeal shock wave therapy on hand grip strength in normal healthy individuals with a hypothesis of dry needling or shock wave on forearm muscles have…
- Trial name
- NCT04645758
- Testing
- Dry needling and Extra corporeal Shock wave therapy
- Where
- Saudi Arabia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Comprehensive Rehabilitation Centre, Medina, Saudi Arabia
Osteoarthrosis, Ultrasound
Ultrasound Findings of Thumb Muscles in 1st Carpometacarpal Osteoarthritis
Carpometacarpal (CMC) joint osteoarthritis is a disorder that is estimated to affect more than one-third of postmenopausal women, leading to decreased muscle strength, reduced joint range of motion, and pain.The pathogenesis of…
- Trial name
- NCT06600464
- Testing
- Ultrasound, Assessment of Muscle Strength in Both Hands, Assessment of Pain Threshold
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Surgery, Sleep Quality
Effect of Progressive Muscle Exercises on Sleep in Urological Surgery
Patients undergoing urological surgery are usually elderly individuals and may experience sleep problems due to factors such as fear of death, anesthesia, and uncertainty.
- Conditions
- Surgery, Sleep Quality, Sleep
- Trial name
- NCT06980558
- Testing
- Progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Atlas University
Subacromial Impingement Syndrome
Effects of Myofascial Chain Tension Modulation Combined With Scapular Corrective Exercise on Scapular Movement Performance and Functional Outcomes in Tennis Players With Subacromial Impingement Syndrome
Subacromial Impingement Syndrome (SIS) is characterized by abnormal scapular motion, including decreased upward rotation, increased internal rotation, and excessive anterior tilting, which impair shoulder and arm function.
- Trial name
- NCT07385378
- Testing
- Instrument-Assisted Soft Tissue Mobilization, Elastic band
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Musculoskeletal Diseases, Musculoskeletal Pain
Effectiveness of Ergonomics Training and Exercise in Esports Players
The aim of this study is to investigate the effectiveness of ergonomics training and exercise in e-sports players.
- Trial name
- NCT06415578
- Testing
- ergonomics training, Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uskudar University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.