Clinical trials: Muscle Disorders
Tibialis Posterior Dysfunction, Emg
Pilot Study to Develop Protocols for Recording Tibialis Posterior EMG
This is an observational pilot study to allow us to create a normal database of muscle function of one of the muscles in the back of the leg (tibialis posterior).
- Trial name
- NCT06131359
- Testing
- Fine wire EMG and Force Frame muscle strength testing
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Pulmonary Disease, Chronic Obstructive, Healthy
Low Load, High-repetitive Elastic Band Resistance Training in COPD
Recent work have shown that low load, high-repetitive single limb resistance training, if compared to a control, can increase limb muscle function and functional exercise capacity in patients with chronic obstructive pulmonary…
- Trial name
- NCT02283580
- Testing
- Single limb, Two limb
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laval University
Uterine Fibroids, Infertility
a Study to Evaluate Adhesion Risk in Fertility Patients' Status Post Laparoscopic Myomectomy.
Premenopausal Women ages 18-42 will undergo a laparoscopic myomectomy. Prior to the myomectomy, adhesions will be assessed using a modified AFS scoring technique.
- Trial name
- VLocmyo (NCT01971060)
- Testing
- surgery utilizing V-Loc suture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Advanced Gynecologic Surgery Institute
Peripheral Arterial Occlusive Disease Fontaine Stage IIa
Acute Local Metabolomic Alterations in Blood and Muscle Tissue in Intermittent Claudication
The most common clinical presentation of lower extremity arterial disease is intermittent claudication. Current understanding of the pathophysiology of intermittent claudication, as well as its treatment options are limited.
- Trial name
- NCT05111379
- Where
- Estonia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Eye Strain
Use of Eye Exercises to Improve Vision
Children in the United States watch an average of twenty-eight hours of television and play around thirteen hours of video games per week.
- Trial name
- NCT03054597
- Testing
- Circular light motion, Diagonal light motion, Peripheral light motion
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Muscle Protein Synthesis, Muscle Atrophy
Exogenous Ketosis During Bed Rest in Older Adults
The goal of this randomized, double-blind, parallel group interventional study is to evaluate the effect of ketone bodies on healthy older adults (65-85 y) during 5 days of bed rest.
- Conditions
- Muscle Protein Synthesis, Muscle Atrophy, Insulin Sensitivity, Mitochondrial Function
- Trial name
- KBR (NCT05679596)
- Testing
- ketone monoester (R)-3-hydroxybutyl (R)-3- hydroxybutyrate
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University
Fractures, Sprain
Epidemiology of Incidents and Accidents in Sport. Influence of Moisture.
sports accidents and incidents are relatively frequent. We hypothesize that the pursuit of good hydration, including days without training or competition could prevent their occurrence
- Conditions
- Fractures, Sprain, Stress Fractures, Aches
- Trial name
- NCT02346786
- Testing
- eau minérale d'Aix-Les-Bains, tap water
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Rhumatologique et Thermal
Muscular Dystrophies, Congenital Myopathy
Assessment of Safety and Acute Effects of a Lower-limb Powered Dermoskeleton in Patients With Neuromuscular Disorders
The aims of the current study are as follow: i) Evaluate the safety, usability, and acute efficiency of a programmable ambulation exoskeleton (KeeogoTM Dermoskeleton System, B-Temia Inc., Quebec, Canada) in patients with…
- Conditions
- Muscular Dystrophies, Congenital Myopathy, Idiopathic Inflammatory Myopathies, Mitochondrial Myopathies
- Trial name
- Exo-KGO1 (NCT05199246)
- Testing
- Lower-limb powered dermoskeleton
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut de Myologie, France
Exercise, Pulmonary Rehabilitation
The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis
The goal of this observational study is to examine the effects of traditional respiratory rehabilitation and respiratory muscle strengthening training added to this program at the genetic level in in patients with rheumatoid…
- Conditions
- Exercise, Pulmonary Rehabilitation, Interstitial Lung Disease, Long Noncoding RNA
- Trial name
- NCT07320846
- Testing
- Standard pulmonary rehabilitation programme, Resistive threshold inspiratory muscle training, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postmenopausal Syndrome, Muscle Weakness
The Bilateral Deficit Phenomenon, Functional and Dynamometric Assessment in Postmenopausal Women
The bilateral deficit phenomenon (BLD) is defined as an inability of the neuromuscular system to generate maximal force when two homonymous limb operate simultaneously (bilateral contraction) with respect to the force developed…
- Trial name
- NCT02434185
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Chronic Kidney Failure, Chronic Kidney Diseases
Physical Impairments in Children With Chronic Renal Failure
When the literature is examined, it is seen that the extent to which cough strength, grip strength, physical activity level and quality of life levels are affected in children with chronic kidney failure compared to healthy…
- Trial name
- NCT06981585
- Testing
- Physical Evaluations of Patients with Chronic Kidney Failure, Physical Evaluations of Healthy Children
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Obesity, Menopause
Calorie Restriction With Leucine Supplementation
The purpose of this study is to determine whether consuming additional leucine during calorie restriction induced weight loss has beneficial or harmful effects on multi-organ (liver, muscle, adipose tissue) insulin sensitivity…
- Conditions
- Obesity, Menopause, Osteoporosis, Sarcopenia
- Trial name
- NCT01757340
- Testing
- Weight loss with normal protein and leucine intake, Weight loss with protein/leucine supplementation
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Sleep Apnea, Obstructive
Effect of Desipramine on Genioglossus Muscle Activity in Healthy Adults Study A
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. OSA patients show a marked reduction in upper airway (UA) dilator muscle activity at sleep onset and this phenomenon…
- Trial name
- DESOSA (NCT02428478)
- Testing
- Desipramine
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Spinal and Bulbar Muscular Atrophy, Kennedys Disease
Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)
Background: SBMA is an inherited chronic disease. It affects males in mid to late adulthood. It causes slowly progressive weakness of muscles and hand tremors. Researchers want to learn more about the effects of SBMA.
- Conditions
- Spinal and Bulbar Muscular Atrophy, Kennedys Disease, Motor Neuron Disease
- Trial name
- NCT04944940
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Endometriosis, Chronic Pelvic Pain
Pelvic Floor Muscle Function and Endometriosis-Related Pelvic Pain
Our study aims to investigate the associations between endometriosis-related pelvic pain and pelvic floor muscle strength, endurance, and relaxation ability, as well as quality of life, physical activity, and the presence of…
- Conditions
- Endometriosis, Chronic Pelvic Pain, Pelvic Pain Associated With Endometriosis or Adenomyosis
- Trial name
- NCT07713108
- Where
- Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Fibromyalgia
The Effects of Training and Relaxation on Fibromyalgia.
Effects of physical training and relaxation exercise on pathophysiological mechanisms and symptoms in finbromyalgia patients.
- Trial name
- NCT01226784
- Testing
- Physcial activity
- Where
- 3 sites in Sweden
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Musculoskeletal Pain, School Health
Effectiveness of Health Education Program on Musculoskeletal Pain Management in Primary School Students
Musculoskeletal pain during childhood can negatively affect school attendance, physical activity, and social participation. This study will evaluate the effectiveness of the school-based health education program 'SocLaLola'…
- Conditions
- Musculoskeletal Pain, School Health, Sedentary Behaviors, Health Education
- Trial name
- LOLA (NCT07160478)
- Testing
- School Health Program
- Where
- Spain
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Osteoporosis in Post-menopausal Women, Vertebral Body Fractures
Effect of Muscle Stiffness on Vertebral Fractures in Women Over 60
This study aims to assess the quality of lumbar and abdominal core muscles through elastography and evaluate its impact on vertebral fracture risk.
- Conditions
- Osteoporosis in Post-menopausal Women, Vertebral Body Fractures, Balance, Postural
- Trial name
- NCT06687889
- Testing
- Elastography Measurements, Bone Mineral Density Measurement (DEXA), Berg balance scale
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Gastrointestinal Diseases, Chronic Pain
Web-Based Survey of Pain, Stress and Complementary and Alternative Medicine
The investigators are inviting people with fibromyalgia, IBS, interstitial cystitis, chronic pain, and other chronic and recurring conditions to sign up and participate in a year-long Internet-based survey to study the…
- Conditions
- Gastrointestinal Diseases, Chronic Pain, Stress, Anxiety
- Trial name
- PROCAIM (NCT00740233)
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Lateral Epicondylitis
Effects of Mill's Manipulation Along With Muscle Energy Technique in Lateral Epicondylitis
The effects of Muscle Energy Technique intervention have been investigated in recent studies in Lateral Epicondylitis. Some studies have been conducted about mills manipulation and Muscle Energy Technique but according to the…
- Trial name
- NCT06500585
- Testing
- Mill's Manipulation, Mill's Manipulation and Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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