Clinical trials: Muscle Disorders
Systememic Lupus Erythematosus, Systemic Sclerosis (SSc)
Investigation of Type I Interferon Excess in Patients With Systemic Autoimmune Diseases and Genetic Type I Interferonopathies
Systemic autoimmune diseases associated with type I interferon (IFN-I) dysregulation, such as systemic lupus erythematosus, systemic sclerosis, myositis, and mixed or undifferentiated connective tissue diseases, and genetic type…
- Conditions
- Systememic Lupus Erythematosus, Systemic Sclerosis (SSc), Inflammatory Myopathies, Connective Tissue Diseases
- Trial name
- SAFRAN (NCT07837986)
- Testing
- biological samples
- Where
- 3 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Migraine in Children, Complex Regional Pain Syndromes
Supraspinal Processing of Sensory Aspects of Pain
The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients.
- Conditions
- Migraine in Children, Complex Regional Pain Syndromes, Musculoskeletal Pain, Functional Abdominal Pain Syndrome
- Trial name
- SCP (NCT05814497)
- Testing
- Multisensory Task, Graphesthesia, Divided attention
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Sarcopenia
The Extremities Rehabilitation Training System for Sarcopenic Hospitalized Aged 80+ Years
Most previous clinical trials that addressed the rehabilitation training system for sarcopenic elderly subjects focused on community-dwelling older adults who were relatively healthy.
- Trial name
- NCT04497480
- Testing
- Motor-Assisted and Active Resistive Upper/Lower Extremities Rehabilitation Training System
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuxiang Liang
Temporomandibular Disorder
Effectiveness of Physical Teraphy in the Treatment of Myogenic Temporomandibular Disorders
The aim of study is evaluate the effectiveness of physical therapy in of the treatment myogenic temporomandibular disorders. They will enrolled 100 patient which will be divided into two groups.
- Trial name
- NCT03726060
- Testing
- control group, test group
- Where
- Italy
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Paolo Pillastrini
Sarcopenic Obesity, Spinal Cord Injuries
Sarcopenic Obesity in Neurodisabilities
To describe the frequency and thresholds for sarcopenic obesity in neurodisabled persons and the fat and lean mass distribution based on various neurodisabilities
- Conditions
- Sarcopenic Obesity, Spinal Cord Injuries, Stroke, Multiple Sclerosis
- Trial name
- SarcObeNDS (NCT03863379)
- Testing
- whole body DXA
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dionyssiotis, Yannis, M.D.
Polymyalgia Rheumatica
Lymphocyte and Cytokine Disturbances in Polymyalgia Rheumatica
Pathophysiology of polymyalgia rheumatica (PMR) is ill defined. This study aims at characterizing immunological abnormalities in PMR patients, and to assess the effects of tocilizumab therapy on this abnormalities.
- Trial name
- TENOR-IMMUNO (NCT02888496)
- Testing
- tocilizumab
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Sarcopenia
Measurement of Sarcopenia at Post-stroke Rehabilitation Outcome
The purposes of this study are 1. To explore effect of sarcopenia on recovery of post stroke hemiplegia 2. To explore the effect of stroke on sarcopenia and relationship between the degree of sarcopenia and respiration and…
- Trial name
- NCT02793362
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bucheon St. Mary's Hospital
Cystic Fibrosis
Whole Body Vibration - a New Therapeutic Approach to Improve Muscle Function in CF
The purpose of this study is to evaluate the effects of whole body vibration (WBV) on muscle function in adult CF-patients.
- Trial name
- NCT00388466
- Testing
- GALILEO
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Fibromyalgia, Systemic Lupus Erythematosus
Membrane Polyunsaturated Fatty Acid Content in Fibromyalgia and Systemic Lupus Erythematosus (SLE)
Polyunsaturated omega-3 fatty acids (ω3 PUFAs) are essential nutrients. Studies indicate that the incidence of Major Depression (MD) is inversely related to the consumption of fish (which are rich in ω3-PUFAs) and to the…
- Trial name
- NCT01460680
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Urinary Incontinence (UI)
Posture, Core Stabilization, Respiratory Muscle Strength and Quality of Life in Women With Urinary Incontinence
When the literature was examined, it was observed that there were studies on parameters such as quality of life, pelvic floor muscle strength in women with urinary incontinence, but there were not enough studies on posture…
- Trial name
- NCT06988683
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Muscle Spasticity, Paralysis; Cerebral
The Decline in Walking Performance in Adults With Cerebral Palsy - Influence of Performance Fatigability
Due to an early brain injury occurring in antenatal or postnatal, cerebral palsy (CP) causes alteration in motor function with posture and gait disorders.
- Trial name
- FAT-GAIT (NCT06163950)
- Testing
- Fatigability assessment
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Muscle Damage, Muscle Inflammation
The Effects of High Dose Fish Oil Supplementation on Delayed Onset Muscle Soreness and Inflammatory Markers
The purpose of this study is to determine the effects of fish oil supplementation (Lovaza, GlaxoSmithKline) on muscle strength, muscle soreness and inflammation following exercise.
- Trial name
- NCT00805870
- Testing
- Lovaza (omega-3-acid ethyl esters), Wheat Germ Oil
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Michigan University
Insomnia, Healthy Adult
The Impact of Acute Pain on Sleep Parameters in the Insomnia Population and Healthy Controls
This study investigates how acute exercise-induced muscular pain affects sleep quality and sleep architecture in people with insomnia compared to healthy sleepers.
- Conditions
- Insomnia, Healthy Adult, Sleep, Musculoskeletal Pain
- Trial name
- NCT07826650
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Neuromuscular Diseases
Muscle Oxygenation in Effort in Neuromuscular Diseases
Previous studies showed modifications of muscle oxygenation parameters in muscular dystrophies du to an impairment or an absence of dystrophin.
- Trial name
- OXYNEMU (NCT02789059)
- Testing
- muscle oxygenation
- Where
- 3 sites in France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Temporomandibular Dysfunction (TMD)
Cervical Proprioception, Masticatory Pain Threshold and Craniovertebral Angle in TMD
Temporomandibular disorder (TMD) is a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures of the head, neck, and cervical region.
- Trial name
- NCT07681570
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Falls, Osteopenia
Effect of a Wii Fit Intervention on Components of Fall Risk in Middle-aged Women
Losses of muscular fitness/balance are common occurrences with aging that can lead to an increased fall-risk. The accelerated bone loss that may accompany menopause makes some women even more "at-risk" for serious consequences…
- Trial name
- NCT01897467
- Testing
- Wii Fit, Wait-List Control
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Pain, Stress
Norwegian Psychomotor Physiotherapy - The Effect on Quality of Life
More and more people suffer from stress-related illness and ailments that can greatly affect the individual's experienced quality of life and sense of coping since pain, physical, mental and social functioning are closely linked.
- Conditions
- Pain, Stress, Psychosomatic Diseases, Muscle Skeletal Disorders
- Trial name
- NCT02282007
- Testing
- Individual NPMP to the participants
- Where
- 2 sites in Norway
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Myofascial Pain Syndrome
Effectiveness of a Massage Instrument Compared to Placebo for Upper Trapezius Muscle Pain
The purpose of this study was to determine if using a specialized massage tool was more effective than a placebo treatment in relieving pain in the upper trapezius muscle along the top of the shoulder.
- Trial name
- NCT01167036
- Testing
- FascialEdge instrument
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Anglo-European College of Chiropractic
Healthy, Muscular Dystrophy
Studies of Patients With Skin Disease, Patients With Neurological Degenerations, and Normal Volunteers
It is proposed that patients with skin disease due to presumed immunologic, genetic or viral-induced abnormalities, patients with neurological degenerations, and normal controls be evaluated with various in vitro studies of…
- Conditions
- Healthy, Muscular Dystrophy, Retinal Degeneration, Skin Diseases
- Trial name
- NCT00001164
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Obesity, Non-insulin-dependent Diabetes Mellitus
Effects of HBO Therapy on Muscular Insulin Resistence in Type 2 Diabetes
Hyperbaric oxygen therapy (HBO) is applied for several diseases. The effect on insulin sensitivity is yet unknown. Hypothesis: HBO therapy improves insulin sensitivity in patients.
- Trial name
- NCT01472328
- Testing
- HBO therapy, Hyperbaric room air
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center