Clinical trials: Muscle Disorders
Overweight and/or Obesity
Effects of Whole-Body High-Intensity Interval Training on Fitness in Overweight Adults
This study aims to evaluate the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults with overweight and obesity.
- Trial name
- WB-HIIT (NCT07582718)
- Testing
- Whole-Body High-Intensity Interval Training (WB-HIIT)
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Université Libre de Bruxelles
Centronuclear Myopathy
Multispectral Optoacoustic Tomography for Advanced Imaging of Centronuclear Myopathy
Twenty patients with centronuclear myopathy and twenty age- and sex-matched, muscle-healthy controls will undergo diagnostic examination.
- Trial name
- MOSAIC (NCT07021820)
- Testing
- MSOT
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Breast Cancer
Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors
Exercise training has beneficial effects in cancer survivors to minimize some of the side effects of cancer and its treatment and improve long-term prognosis, but there are numerous hurdles for individuals diagnosed with, and…
- Trial name
- NCT02739620
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Vermont
Pheochromocytoma/Paraganglioma, Rhabdomyosarcoma
Ivonescimab in the Treatment of Multiple Advanced Tumors
The goal of this clinical trial is to learn if Ivonescimab works to treat advanced rare tumors including cohort 1: PAGET's disease of scrotum with infiltrating sweat gland carcinoma.
- Conditions
- Pheochromocytoma/Paraganglioma, Rhabdomyosarcoma, Paget Disease, Extramammary, Renal Angiomyolipoma
- Trial name
- NCT06683846
- Testing
- Ivocizumab
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Fudan University
Diagnosis and Follow up on Upper Extremity Interventions
Quantification of Kinematics and Muscle Activity Patterns of the Upper Extremities of Individuals With Motor Disabilities
The subjet is sitting on a chair and in front of him an adjustable (height) table with a glass of water. 17 passive reflective markers are placed on his upper extremities and torso.
- Trial name
- NCT02162342
- Testing
- Rehabilitative treatment
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Lateral Elbow Tendinopathy (Tennis Elbow)
Diagnostic Accuracy of the Clinical Tests and the Ultrasonography in Lateral Elbow Tendinopathy
Lateral elbow tendinopathy (LET) is the most common cause of elbow pain. Even though provocation tests such as Cozen's test, Mill's test or Maudsley test; musculoskeletal ultrasound or magnetic resonance imaging can be used for…
- Trial name
- NCT07347873
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Temporomandibular Disorders
Dry Needling vs Injection in Patients With Temporomandibular Disorders
The main objective is to compare the effectiveness of dry needling in improving pain and disability versus placebo, and versus infiltration, in patients with myofascial temporomandibular dysfunction in the short, medium and long…
- Trial name
- NCT04726683
- Testing
- Dry needling and injection
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Josue Fernandez Carnero
Duchenne Muscular Dystrophy (DMD)
A Study to Assess the Safety, Tolerability and Preliminary Efficacy of ASP0367 (MA-0211) in Pediatric Male Participants With Duchenne Muscular Dystrophy (DMD)
The primary purpose of this study is to evaluate the safety and tolerability of ASP0367. This study will also evaluate the pharmacokinetics, pharmacodynamics and efficacy on muscle function of ASP0367.
- Trial name
- NCT04184882
- Testing
- Bocidelpar
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- Astellas Pharma Inc
Non-Muscle-Invasive Bladder Cancer, Bladder Cancer
The Prognostic Impact of Tumor Location in Non-Muscle-Invasive Bladder Cancer Patients
Based on large sample size studies at home and abroad, the prognosis of patients with non-muscular invasive bladder cancer in different sites undergoing transurethral bladder tumor resection was determined, providing important…
- Trial name
- NCT06245759
- Testing
- This was a retrospective study and no patient intervention was performed
- Where
- China
- Volunteers
- 120,000 people
- Sponsor
- Huazhong University of Science and Technology
Fibromyalgia
Attentional Bias Modification in Fibromyalgia Patients (ABM)
There is a growing interest in the potential benefits of attentional bias modification (ABM) training in chronic pain patients. However, studies examining the effectiveness of ABM programs in fibromyalgia patients have…
- Trial name
- ABM (NCT05905159)
- Testing
- ABM, Control
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Rey Juan Carlos
Autoimmune Diseases, Non-small Cell Lung Cancer
Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease
The purpose of this study is to explore the safety, tolerability and activity of Nivolumab, a PD-1 inhibitor, in cohorts of patients with autoimmune disease.
- Conditions
- Autoimmune Diseases, Non-small Cell Lung Cancer, Rheumatoid Arthritis, Psoriasis
- Trial name
- NCT03656627
- Testing
- Nivolumab
- Where
- 9 sites in United States
- Volunteers
- 7 people
- Sponsor
- Alliance Foundation Trials, LLC.
Temporomandibular Joint Disorder
Validation and Cultural Adaptation of Jaw Functional Limitation Scale-20
Temporomandibular joint (TMJ) disorder (TMD) is common. Jaw Functional Limitation Scale-20 (JFLS) is a validated tool for the evaluation of patients suffering from TMD
- Trial name
- NCT07789197
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Duchenne Muscular Dystrophy
CoQ10 and Prednisone in Non-Ambulatory DMD
This study will help determine if CoQ10 and prednisone, alone and as a combination decrease the decline in cardiopulmonary and skeletal muscle function that occurs in the wheelchair confined phase of DMD.
- Trial name
- NCT00308113
- Testing
- Prednisone, Coenzyme Q10
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Cooperative International Neuromuscular Research Group
Temporomandibular Disorder, TMJ Disc Displacement With Reduction
Telerehabilitation for TMD
This study will compare after physical therapy for Temporomandibular Disorders (TMD) performed either in-person or virtually using telerehabilitation.
- Conditions
- Temporomandibular Disorder, TMJ Disc Displacement With Reduction, TMJ Disc Displacement Without Reduction, Masticatory Myofascial Pain
- Trial name
- NCT05318313
- Testing
- Telerehabilitation
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- University of Minnesota
Spastic Foot, Stroke
Triceps Surae Ultrasonographic Characteristics in Hemiparetic Stroke Survivors
This study aims to evaluate, in hemiparetic patients, changes in muscle ultrasound structure about the focal treatment of spasticity with botulinum toxin type A.
- Trial name
- TriUS (NCT05097482)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Alessio Baricich
De Quervain Disease
Comparative Effects of Paraffin Bath Therapy and ESWT on Quality of Life and Sleep in De Quervain Tenosynovitis
There is no study in the literature comparing effects of both paraffin bath therapy and Extracorporeal Shock Wave Therapy (ESWT) on life and sleep quality of patients with De Quervain Tenosynovitis .
- Trial name
- NCT05423223
- Testing
- Paraffin Bath Therapy, Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Yuzuncu Yil University
Dupuytren's Disease
Nodular Shrinking in Dupuytren Disease
Dupuytren disease (DD) is a common hand disorder with disabling finger contractures that may require surgery to restore function.
- Trial name
- Echo (NCT06321991)
- Testing
- Ultrasound measurement
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Trigger Finger
Injection of Hyaluronic Acid Versus Corticosteroid for Treatment of Trigger Finger
The aim of the study is to compare the therapeutic effects of hyaluronic acid versus steroid injections in treating trigger fingers using ultrasound guidance
- Trial name
- NCT04645303
- Testing
- hyaluronic acid (20 mg/2 mL), Triamcinolone acetonide 10mg/ml
- Where
- United Arab Emirates
- Volunteers
- 100 people
- Sponsor
- Dubai Health Authority
Hyperalgesia, Healthy Subjects
Spread of Muscle Hyperalgesia and Pain in a Low Dose NGF-induced Pain Model
The purpose of this study is to investigate and determine the time course and distribution on muscle hyperalgesia and muscle pain in a repeated, low dose NGF model.
- Trial name
- NCT03217942
- Testing
- NGF
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Obesity
Functional Inspiratory Muscle Training in Obese Individuals
In obese individuals, increased adipose tissue and systemic inflammation play a key role in the development of cardiometabolic diseases, pulmonary system dysfunction, and many respiratory diseases.
- Trial name
- NCT06280183
- Testing
- Functional Inspiratory Muscle Training, Aerobic+Resistive Exercise Traning
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Biruni University
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