Clinical trials: Muscle Disorders
Forearm Muscle Strength, Radial Bone Health
SUPERVISED RESISTANCE AND WEIGHT-BEARING EXERCISE IN INSTITUTIONALIZED OLDER ADULTS
This quasi-experimental controlled study evaluated the effects of a six-month supervised resistance and weight-bearing exercise program on forearm muscle strength and radial bone health in institutionalized older adults.
- Conditions
- Forearm Muscle Strength, Radial Bone Health, Institutionalized Older Adults Keywords / MeSH
- Trial name
- SRWBE (NCT07831031)
- Testing
- Forearm-Focused Resistance and Upper-Extremity Weight-Bearing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Sarcopenia, High Blood Pressure
The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia
Current prevention and treatment of high blood pressure (BP) in sarcopenia, by non-pharmacological approaches remain limited and are far from optimal.
- Conditions
- Sarcopenia, High Blood Pressure, Hypertension
- Trial name
- INERTIA (NCT04255745)
- Testing
- progressive resistance training
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Fibromyalgia
Effectiveness of Oral Magnesium Supplementation in Fibromyalgia Patients Not Responding to Standard Treatment
Fibromyalgia is a complex widespread pain disorder. OBJECTIVES To evaluate the effectiveness of oral magnesium supplementation in reducing symptom severity among fibromyalgia patients who have not responded to standard treatment…
- Trial name
- NCT07585045
- Testing
- Magnesium glycinate, Vitamins
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Shaikh Zayed Hospital, Lahore
Stress Urinary Incontinence
Pelvic Floor Muscle Training With a Digital Therapeutic Device to Standard Exercises for Stress Urinary Incontinence
A virtual prospective randomized controlled study to evaluate the efficacy of using the leva® Pelvic Digital Health System (PDHS) to perform PFMT compared to a standard home exercise home program for the treatment of SUI/SMUI.
- Trial name
- NCT04508153
- Testing
- Leva Pelvic Digital Health System, Kegel exercises
- Where
- 3 sites in United States
- Volunteers
- 369 people
- Sponsor
- Renovia, Inc.
Myofascial Pain Syndrome
Comparing Instrument-Assisted Soft Tissue Mobilization and Muscle Energy Technique for Myofascial Pain Syndrome in Women
This study compares Instrument-Assisted Soft Tissue Mobilization (IASTM) and Muscle Energy Technique (MET) in female patients with myofascial pain syndrome.
- Trial name
- NCT07904559
- Testing
- Control Group (A):, Instrument-Assisted Soft Tissue Mobilization (IASTM), Muscle Energy Technique (MET)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Cardiac Arrest With Successful Resuscitation, Hypothermia
Skeletal Muscle Paralysis in Hypothermic Patients After Cardiac Arrest
Mild hypothermia improves neurological outcome after cardiac arrest. Neuromuscular blockers are in use, together with analgesia and sedation, during the cooling process in many centers to prevent shivering.
- Conditions
- Cardiac Arrest With Successful Resuscitation, Hypothermia, Skeletal Muscle Relaxant Overdose
- Trial name
- RELAX (NCT01719770)
- Testing
- rocuronium
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Diaphragm Thickness, Dyspnoea
Abdominal Air-Pressure Resistance Versus Abdominal Weight Training for Improving Diaphragm Function in Healthy Young Adults
This study aims to compare the effects of abdominal air pressure resistance training, abdominal weight training, and breathing exercises on diaphragmatic strength, endurance, and physiological responses in young healthy adults.
- Trial name
- NCT07795905
- Testing
- Abdominal Air Pressure Resistance Training, Abdominal Weight Training (AWT), Breathing Exercise Control (BE)
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Aged
Factors Affecting Kinesiophobia in the Elderly
In epidemiological studies, the incidence of foot problems has been found to be high as a result of the increase in life expectancy.
- Trial name
- NCT06138366
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Cerebral Palsy (CP), Cerebral Palsy, Hemiplegic
Effect of Whirlpool Therapy Combined With Botulinum Toxin in Children With Cerebral Palsy
This study aims to investigate the effects of adding whirlpool therapy to standard rehabilitation in children with cerebral palsy who recently received botulinum toxin-A injections.
- Trial name
- NCT07690722
- Testing
- Conventional Rehabilitation, Whirlpool Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Ankara Etlik City Hospital
Radiographic Axial Spondyloarthritis
Respiratory Function and S-index in Radiographic Axial Spondyloarthritis
Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory disease that may lead to reduced chest expansion and impaired respiratory function due to thoracic involvement.
- Trial name
- NCT07515131
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gazi University
Duchenne Muscular Dystrophy (DMD)
An Open-Label Extension Study to Evaluate the Long-term Safety and Efficacy of BMN 351 in Participants With Duchenne Muscular Dystrophy
This open-label extension study aims to evaluate the long-term safety and tolerability of weekly BMN 351 infusions, as well as to assess the effect of BMN 351 on physical function, in participants with DMD who participated in the…
- Trial name
- NCT07573631
- Testing
- BMN 351
- Where
- 6 sites in Italy, Netherlands and 3 more
- Volunteers
- 18 people
- Sponsor
- BioMarin Pharmaceutical
Temporomandibular Joint Disorders
Intra-articular Injection in Arthroscopic Management of Temporomandibular Diseases
The aim of this study is to evaluate the efficacy of intra-articular injection of platelet rich plasma versus hyaluronic acid following diagnostic arthroscopy in the management of patients suffering from degenerative…
- Trial name
- NCT04936945
- Testing
- Temporomandibular joint arthroscopy plus intra-articular injection
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus
Stellate Ganglion Block and Dexmedetomidine for Postoperative Sleep in Women Undergoing Laparoscopic Gynecologic Surgery
Study Objectives This study aims to investigate the effects of preoperative stellate ganglion block and intraoperative intravenous dexmedetomidine on postoperative sleep disturbance in patients undergoing laparoscopic gynecologic…
- Conditions
- Uterine Fibroids (Leiomyoma), Adenomyosis of Uterus, Endometriosis, Endometrial Cancer
- Trial name
- NCT07860203
- Testing
- DEX 0.2 μg/kg/h., SGB
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Catherin Zhang
Frailty, Stroke
Body Composition, Frailty, and Function in Rehabilitation
The investigators are investigating if body composition measures - in particular muscle mass, body fat, and something called the phase angle - are able to reliably predict functional outcomes for patients who are in an acute…
- Conditions
- Frailty, Stroke, Debility Due to Disease
- Trial name
- NCT06527742
- Where
- Singapore
- Volunteers
- 345 people
- Sponsor
- Changi General Hospital
Bladder Cancer
Efficacy and Safety of Pseudomonas Aeruginosa for Intermediate and High-risk Non-muscle Invasive Bladder Cancer
This is a multicenter, single-arm study to evaluate the efficacy and safety of Pseudomonas aeruginosa the treatment of patients with intermediate and high risk non-muscle invasive bladder cancer.
- Trial name
- NCT05975151
- Testing
- Pseudomonas aeruginosa
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Qilu Hospital of Shandong University
Stress Urinary Incontinence, Postpartum
Differences in the Effectiveness of Electromagnetic Stimulation Therapy and Kegel Exercises Based on Compliance, Subjective - Objective Symptoms and Pelvic Floor Muscle Strength in Postpartum Stress Urinary Incontinence
Electromagnetic stimulation is a new modality and alternative in women with urinary incontinence (UI). However, there was not much evidence that compares the use of electromagnetic stimulation to Kegel Exercises in post-partum…
- Trial name
- NCT05021302
- Testing
- NOVAMAG NT-60, Kegel Exercises
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Indonesia
Fibromyalgia
Intervention for Self-regulation to Physical Exercise in People With Fibromyalgia
This work is part of a broader research with women with fibromyalgia. The aim of this study is to establish the effectiveness of implementation intentions to manage the preference for avoiding pain and fatigue and stop walking…
- Trial name
- IAMEFI (NCT04655053)
- Testing
- Goal intention, Implementation intention to initiate the behavior, Implementation intention to manage the goal preference (avoiding behavior or not)
- Where
- Spain
- Volunteers
- 252 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Limb Girdle Muscular Dystrophy, Limb-Girdle Muscular Dystrophy Type 2
A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)
The purpose of this study is to evaluate the safety and tolerability of a single intravenous infusion of AB-1003 in adults diagnosed with limb girdle muscular dystrophy type 2I/R9 (LGMD2I/R9).
- Conditions
- Limb Girdle Muscular Dystrophy, Limb-Girdle Muscular Dystrophy Type 2, LGMD2I, Muscular Dystrophy
- Trial name
- NCT05230459
- Testing
- AB-1003 dose level 1, AB-1003 dose level 2
- Where
- 6 sites in United States
- Volunteers
- 9 people
- Sponsor
- AskBio Inc
Paramyotonia Congenita, Nondystrophic Myotonia
Using MRI in Patients With Non-dystrophic Myotonia to Access Muscle Contractility
The aim of this project is (1) to investigate whether or not structural muscle abnormalities could be a consequence of the disorder and (2) to provide further clinical description of this rare phenotype.
- Trial name
- NCT04808388
- Testing
- MRI
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Compartment Syndromes, Polytrauma
Non-invasive Limb Compartment Pressure Measurement
Compartment syndrome (CS) is a serious complication of soft-tissue injuries in patients with fractures of the musculoskeletal apparatus.
- Conditions
- Compartment Syndromes, Polytrauma, Burn Injury
- Trial name
- FNO-TRAUMA-CPM (NCT03730688)
- Testing
- Conventional compartment pressure measurement, Experimental compartment pressure measurement
- Where
- 2 sites in Czechia
- Volunteers
- 70 people
- Sponsor
- University Hospital Ostrava
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