Clinical trials: Muscle Dysfunction
Pelvic Floor Dysfunction
The Evaluation of Pelvic Floor Muscle Function: A Reliability and Correlation Study
1. To explore the correlations among measures of PFM strength between using vaginal palpation quantified by modified Oxford Grading Scale and Levator ani testing and manometry in PHENIX instrument; 2.
- Trial name
- NCT03511911
- Testing
- evaluation of pelvic floor muscle function through the PHENIX instrument, vaginal palpation
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Hypertension, Atherosclerosis
Age-Related Changes in Body Composition
Background: Advancing age is associated with greater risk of heart disease. High blood pressure and hardening of the arteries also have more complications with age.
- Trial name
- NCT01517113
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Diabetes Mellitus, Type 2
Resistance Training in Diabetic Elder Patients
The purpose of this study is to investigate the effect of a 12-week progressive resistance training program on the skeletal muscle function, glycemic control, functional capacity, and quality of life in the elderly with type 2…
- Trial name
- NCT01638351
- Testing
- Resistance exercise, Usual care
- Where
- Taiwan
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Temporomandibular Dysfunction (TMD)
Cervical Proprioception, Masticatory Pain Threshold and Craniovertebral Angle in TMD
Temporomandibular disorder (TMD) is a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures of the head, neck, and cervical region.
- Trial name
- NCT07681570
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Diastolic Dysfunction, Systolic Dysfunction
Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol ES
Our local IRB approved clinical studies seeking proof of principle for the hypothesis that SFN can be safely administered to humans at doses sufficient to protect age-associated cardiac dysfunctions.
- Conditions
- Diastolic Dysfunction, Systolic Dysfunction, Diastolic Heart Failure
- Trial name
- CardiacAging (NCT05408559)
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Chronic Pelvic Pain Syndrome
Vaginal Baclofen Suppositories in Chronic Pelvic Pain
The purpose of this study is to evaluate if baclofen vaginal suppositories improve symptoms of Chronic Pelvic Pain (CPP). Participants in this study will take four short questionnaires prior to being randomized.
- Trial name
- NCT05968937
- Testing
- 20 mg baclofen vaginal suppository daily per vagina
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Healthy, Neuromuscular Disease
Electromyography to Diagnose Neuromuscular Disorders
This study will investigate problems with muscle weakness and control using electromyography-a test of nerve-muscle cell communication.
- Conditions
- Healthy, Neuromuscular Disease, Postpoliomyelitis Syndrome
- Trial name
- NCT00004553
- Testing
- Electromyography
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Pelvic Floor Disorders, Diastasis Recti
Pelvic Floor Muscle Function, Pelvic Floor Dysfunction and Diastasis Recti Abdominis in Postpartum Women
Background: Pregnancy and childbirth are factors that affect a woman's pelvic floor. Pelvic floor disorders (PFD) often occur in the perinatal period.
- Trial name
- NCT05004402
- Where
- Poland
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Muscle Strength, Healthy
Reference Equations and Normative Data for Isometric Quadriceps and Handgrip Muscles STrength in Southern European Populations - RESTart: a Multicentre Study
This observational study aims to learn about peripheral muscle strength in healthy adults and people with chronic respiratory diseases.
- Conditions
- Muscle Strength, Healthy, Chronic Respiratory Diseases
- Trial name
- RESTart (NCT07628530)
- Where
- Spain
- Volunteers
- 2,815 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Sarcopenia, Frailty at Older Adults
Targeting Sarcopenia and Frailty: Multicomponent Exercise With Focal Muscle Vibration
This study aimed to evaluate the efficacy of multicomponent exercises (aerobic exercises, strength exercises, and balance exercises), individualized with the application of a focal muscle vibration machine at the lower…
- Conditions
- Sarcopenia, Frailty at Older Adults, Cognitive Impairment, Adherence
- Trial name
- NCT07049809
- Testing
- Focal Muscle Vibration, Multicomponent Exercise
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
HIV Infections
Use of Muscle Spectroscopy to Evaluate Mitochondrial Dysfunction in HIV-Infected Patients
The purpose of this study is to see if magnetic resonance spectroscopy (MRS) can be used to detect damage to the mitochondria in HIV-infected patients taking nucleoside reverse transcriptase inhibitor (NRTI) drugs.
- Trial name
- NCT00036478
- Where
- 8 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
Skeletal Muscle Function in Interstitial Lung Disease
Dyspnea (i.e. breathlessness) and exercise intolerance are common symptoms for patients with interstitial lung disease (ILD), yet it is not known why.
- Conditions
- Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis, Hypersensitivity Pneumonitis, Scleroderma
- Trial name
- NCT03800017
- Testing
- Hyperoxia
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain, Temporomandibular Joint Disorders
Effectiveness of Physiotherapy Treatments in Temporomandibular Joint Dysfunction
The study will determinate the influence of four selected physiotherapeutic procedures on the pain intensity, the bioelectrical activity of the masseter muscle, and the range of mandibular mobility in patients with TMDs…
- Conditions
- Pain, Temporomandibular Joint Disorders, Muscle Hypertonia, Myofacial Pain
- Trial name
- NCT05619380
- Testing
- physiotherapy treatment
- Where
- Poland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Thyroid Dysfunction
The Effect of Thyroid Dysfunction
The aim of this study is to investigate the effect of thyroid dysfunction on pain, symptoms, attitudes, fatigue, foot parameters, muscle strength, and lower extremity performance in women with a menstrual cycle, and to compare…
- Trial name
- NCT07552103
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Segmental Dysfunction of the Pelvic Region
Iball & Pelvic Floor Muscle Training
he postpartum period is vulnerable to dysfunction of the pelvic floor musculature, which is associated with incontinence, pain, reduced stability of the core and functional deficits.
- Trial name
- iball (NCT02865954)
- Testing
- iball (mhealth application)
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Chronic Obstructive Pulmonary Disease (COPD)
Sensorimotor Function in COPD
The aim of this study was to investigate the level of sensorimotor function impairment according to disease stage in individuals with Chronic Obstructive Pulmonary Disease (COPD) and to determine whether functional differences…
- Trial name
- NCT07825636
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Temporomandibular Joint Disorders, Voice Change
Impact of Temporomandibular Joint Dysfunction on Objective and Subjective Vocal Measures
The present study aims to investigate the impact of temporomandibular joint dysfunction (TMD) on objective and subjective vocal parameters and the quality of life in affected patients.
- Trial name
- NCT06046521
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Fibromyalgia
Electrophysiological Findings in Fibromyalgia Patients
Fibromyalgia Syndrome (FMS); It is a chronic condition characterized by widespread body pain, sleep disturbance, fatigue, impaired cognitive functions, and anxiety (1).
- Trial name
- NCT04845737
- Testing
- sympathetic skin response measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Chronic Obstructive Pulmonary
Involvement of Plasmatic Factors in the Peripheral Muscle Dysfunction of COPD Patients - In Vitro Study
Chronic Obstructive Pulmonary Patients is a defined by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or…
- Trial name
- NCT03197909
- Testing
- Determination of pro-inflammatory plasma factors
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Psychosomatic Symptoms, Temporomandibular Disorder (TMD)
Psychosomatic Symptoms in Patients With Myofascial Pain and Temporomandibular Joint Dysfunction
Temporomandibular joint disorder poses an intricate etiology. Biomechanical, neuromuscular and psychosocial factors may contribute to the disorder among which psychological and psychosocial disturbances have shown strong direct…
- Trial name
- Psychosomatic (NCT07385781)
- Testing
- Casr
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bahria University