Clinical trials: Muscle Dysfunction
Pain, Discomfort
Association Among Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health in Caregivers of Stroke Individuals
This study aims to examine pain perception, temporomandibular disorder severity and spine health in caregivers of stroke patients.
- Conditions
- Pain, Discomfort, Caregiver, Temporomandibular Disorder
- Trial name
- NCT06052735
- Testing
- Correlation research
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Septic Shock
Muscle Ultrasound Study in Shock Patients
Intensive Care Unit (ICU) patients are known to lose muscle mass and function for many reasons, ranging from prolonged immobilization, to the effects of ICU treatments such as mechanical ventilation (MV), to the critical illness…
- Trial name
- MUSiShock (NCT04550143)
- Testing
- Diaphragm ultrasound (DUS), Peripheral Muscle Ultrasound (PMUS), Airway occlusion pressure (P0.1)
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Temporomandibular Disorders, Myofascial Pain Dysfunction Syndrome
Yoga-Based Exercise Program For Temporomandibular Disorders
Aims:The study was conducted to investigate the effect of Yoga-based exercise program on pain, range of motion(ROM), sleep quality, depression and quality of life in female patients with myofascial pain dysfunction(MPD) of…
- Conditions
- Temporomandibular Disorders, Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint Pain, Range of Motion
- Trial name
- NCT04982601
- Testing
- Yoga Exercises
- Volunteers
- 39 people
- Sponsor
- Medipol University
Temporomandibular Joint Disorders, Voice Change
Impact of Temporomandibular Joint Dysfunction on Objective and Subjective Vocal Measures
The present study aims to investigate the impact of temporomandibular joint dysfunction (TMD) on objective and subjective vocal parameters and the quality of life in affected patients.
- Trial name
- NCT06046521
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Erectile Dysfunction, Urinary Incontinence
Male Pelvic Floor Muscle Rehabilitation Exercises
Phase I G128 Study Objective The ischiocavernosus (IC) and bulbospongiosus (BS) muscles are vital components of the superficial perineal layer, serving as the foundation for male sexual health and performance.
- Conditions
- Erectile Dysfunction, Urinary Incontinence, Premature Ejaculation
- Trial name
- NCT07451808
- Testing
- Male Pelvic Floor Rehabilitation #1
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dream Video LLC
Temporomandibular Joint Dysfunction Syndrome, Burning Mouth Syndrome
Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain
Patients with chronic masticatory muscle pain (i.e., pain greater than three months) or patients with burning mouth syndrome participate in this study.
- Trial name
- NCT00716807
- Testing
- nalbuphine plus naloxone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of California, San Francisco
Weaning From Mechanical Ventilation
Assessment of Inspiratory Muscles Strength and Endurance Evolution on Difficult to Wean Patients in Intensive Care Unit
Ventilator-induced diaphragmatic dysfunction appears to contribute to slow weaning from mechanical ventilation. Several trials of inspiratory muscle training to facilitate weaning in intensive care have been performed, with…
- Trial name
- EFES (NCT03140267)
- Testing
- Difficult to wean patients
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Bordeaux
Bruxism, Pelvic Pain
Bruxism, Pelvic Pain, Erectile Dysfunction, and Anxiety in Young Adult Men
Bruxism is a parafunctional activity characterized by clenching or grinding of the teeth during wakefulness or sleep. Increasing evidence suggests that bruxism is not only related to orofacial structures but may also be…
- Conditions
- Bruxism, Pelvic Pain, Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Pain Dysfunction Syndrome
- Trial name
- NCT07469345
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Urinary Incontinence, Stress Urinary Incontinence
Efficacy of the Use of Vaginal Balls for the Improvement of Urinary Incontinence and Sexual Function in Women.
Asess if adding vaginal spheres treatment to the conventional Pelvic Floor Muscle Trainning (PFMT) produces a greater decrease in the severity of the stress urinary incontinence or a greater perceived quality of life related to…
- Conditions
- Urinary Incontinence, Stress Urinary Incontinence, Sexual Dysfunction
- Trial name
- NCT05732844
- Testing
- Intervention group with Enna pelvic ball, Control group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- RAPbarcelona
Heart Failure
The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects
Background: People are living longer and are more likely to survive a heart attack if they have one. Longer life expectancy is good but it also means more people get chronic heart failure over time.
- Trial name
- NCT03565328
- Testing
- Nicotinamide Riboside
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Temporo-mandibular Dysfunction, Disc Displacement
Effects of Orofacial Myofunctional Therapy and Cervical Stabilization Exercises in Patients With Axis-i Group Iia Temporomandibular Dysfunction
The proposed PhD study, "Effects of Orofacial Myofunctional Therapy and Cervical Stabilization Exercises in Patients with Axis-I, Group II-a Temporomandibular Dysfunction," aims to evaluate an integrated physiotherapy approach…
- Conditions
- Temporo-mandibular Dysfunction, Disc Displacement, Axis I Diagnosis, Disc Displacement With Reduction
- Trial name
- OMT (NCT07853144)
- Testing
- Cervical Stabilization Exercises, Orofacial Myofunctional Therapy
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- University of Lahore
Sarcopenia, Hip Fracture
Prevalence and Pathophysiology of Sarcopenia in the Elderly Patient With Hip Fracture
Sarcopenia is the loss of muscle mass and function that accompanies aging. The term sarcopenia comes from the Greek "sarx" (flesh) and "penia" (loss).
- Conditions
- Sarcopenia, Hip Fracture, Frailty
- Trial name
- PREFISSARC (NCT01477086)
- Where
- Spain
- Volunteers
- 198 people
- Sponsor
- Hospital Viamed Valvanera, Spain
Muscle Soreness
Effects of Ginger on Muscle Soreness and Dysfunction Stemming From Downhill Running
The objective of the study is to determine whether five days of ginger (Zingiber officinale) supplementation is effective at reducing muscle soreness and improving muscle function following downhill running.
- Trial name
- NCT03028454
- Testing
- Ginger Root
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Fatigue, Musculoskeletal Pain
Complementary Neurosteroid Intervention in Gulf War Illnesses (GWVI)
This study will investigate the use of adjunctive pregnenolone for the following: 1. fatigue that has limited usual activity, 2. musculoskeletal pain involving 2 or more regions of the body and, 3.
- Conditions
- Fatigue, Musculoskeletal Pain, Cognitive Decline
- Trial name
- NCT01956279
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Temporomandibular Joint Dysfunction
Thermograph Evaluation of Masticatory and Cervical Muscles After Physiotherapeutic Treatment in Tmd Subjects
Background: Different therapeutic approaches have been proposed for the treatment of TMD. Myofascial and joint techniques, exercises, intraoral devices, thermal, electro and phototherapy applications, are among the most common.
- Trial name
- TEMCMAPTTS (NCT02822469)
- Testing
- Manual Therapy Treatment
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Daniela Ap. Biasotto-Gonzalez
Segmental Dysfunction of the Pelvic Region
Iball & Pelvic Floor Muscle Training
he postpartum period is vulnerable to dysfunction of the pelvic floor musculature, which is associated with incontinence, pain, reduced stability of the core and functional deficits.
- Trial name
- iball (NCT02865954)
- Testing
- iball (mhealth application)
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Chronic Fatigue Syndrome
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
The main aim of the study is to examine the effect of oral CoQ10 plus NADH (Reconnect®) supplementation twice daily for 8-weeks on the changes in fatigue perception, sleep disturbances, autonomic dysfunction and HRQoL assessed by…
- Trial name
- CONNeCT (NCT03186027)
- Testing
- Coenzyme Q10 plus NADH, phosphoserine plus vitamin C
- Where
- Spain
- Volunteers
- 282 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Fibromyalgia
Growth Hormone in Neuroendocrine Dysfunction With Severe Fibromyalgia Syndrome
The purpose of this study is to evaluate the efficacy of recombinant human growth hormone (r-hGH) treatment in severe fibromyalgia subjects with growth axis dysfunction.
- Trial name
- NCT00933686
- Testing
- Saizen®
- Where
- Spain
- Volunteers
- 113 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Sexual Dysfunction, Myofascial Pain Syndrome
Sexual Dysfunction in Patients With Myofascial Pain Syndrome
This study evaluates the frequency of sexual dysfunction in women with myofascial pain syndrome and its relationship with clinical parameters.
- Trial name
- NCT05727566
- Testing
- visual pain scale (VASpain/fatigue), Beck depression index (BDI), the sexuality-importance score, sexual intercourse frequency
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Konya Beyhekim Training and Research Hospital
Critical Illness Myopathy, Myopathy Critical Illness
Understanding the Mechanisms of Critical Illness Myopathy by Use of a Novel Electrophysiological Method - MVRCs
Critical illness myopathy (CIM) is a disabling condition that develops in critically ill patients. The syndrome is not only a cause of prolonged intensive care hospitalisation but also a main reason for delayed recovery.
- Trial name
- NCT04711070
- Where
- 2 sites in Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sándor Beniczky