Clinical trials: Muscle Dysfunction
Pain, Quality of Life
Protocol Phototherapy Treatment for Fibromyalgia and Temporomandibular Joint Dysfunction
Temporomandibular joint dysfunction is described as a multifactorial disease and can be directly linked to other diseases, being of structural factors of the Stomatognathic System or not, such as fibromyalgia.
- Trial name
- FM and DTM (NCT02279225)
- Testing
- Group Phototherapy, Phototherapy + Physical activity, Physical activity
- Where
- Brazil
- Volunteers
- 61 people
- Sponsor
- University of Nove de Julho
Childhood Cancer, Cancer Survivors
Diaphragm Structure and Function in Childhood Cancer Survivors
The purpose of this research is to study the feasibility of a specific training program for the breathing muscles (inspiratory muscle training) and the effects on how breathing is regulated during exercise in childhood cancer…
- Trial name
- NCT06205251
- Testing
- POWERbreathe Plus IMT
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Maryland, Baltimore
Pelvic Floor Disorders, Diastasis Recti
Pelvic Floor Muscle Function, Pelvic Floor Dysfunction and Diastasis Recti Abdominis in Postpartum Women
Background: Pregnancy and childbirth are factors that affect a woman's pelvic floor. Pelvic floor disorders (PFD) often occur in the perinatal period.
- Trial name
- NCT05004402
- Where
- Poland
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Fibromyalgia, Sexual Dysfunction
Fibromyalgia and Sexual Functıonal Dısorder and Sexual Therapy
investigators aim to re-evaluate the findings of Fibromyalgia in patients whose FSFI scores return to normal levels after sexual therapy, by identifying patients with sexual dysfunction according to the FSFI scale applied in…
- Trial name
- NCT05272345
- Testing
- sexual therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Down Syndrome, Autonomic Dysfunction
Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome
Down syndrome (DS), the most common genetic cause of intellectual disability, is associated with widespread organ dysfunction, including abnormalities in the autonomic nervous system (ANS).
- Trial name
- DIVE (NCT07238465)
- Testing
- Cold Stress, Maximal Dynamic Exercise, Isometric Handgrip Exercise with Post-Exercise Muscle Ischemia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Temporomandibular Disorders (TMDs), Temporo-mandibular Dysfunction
Effects of Orofascial Myofunctional Therapy and Cervical Stabilization Exercises on Temporomandibular Dysfunction
Temporomandibular disorders (TMDs) are among the most common musculoskeletal conditions affecting the craniofacial region and are characterized by pain, joint sounds, restricted movement, and functional limitations.
- Conditions
- Temporomandibular Disorders (TMDs), Temporo-mandibular Dysfunction, Disc Displacement
- Trial name
- OMT (NCT07828587)
- Testing
- orofacial myofunctional therapy, cervical stabilization exercises
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Multisystemic Smooth Muscle Dysfunction Syndrome, ACTA2
A Retrospective and Prospective Natural History of Genetic Vasculopathies
This study will combine retrospective review of medical records from patients with ACTA2 and ongoing collection of clinical data using standardized instruments and intervals on an observational basis from patients with ACTA2.
- Trial name
- NCT06552052
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
TMJ Disorder
Pulsed Electromagnetic Field Therapy for TMJ Dysfunction After Facial Penetrating Injury
This study is aiming to investigate the effect of magnetic therapy in combination with traditional physical therapy on the pain and mouth opening, after facial penetrating wound injury with no facial fractures, that treated…
- Trial name
- NCT04561037
- Testing
- Pulsed Electromagnetic Field therapy (PEMFT), TMJ physical therapy program
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Kafrelsheikh University
Muscle Atrophy or Weakness, Ventilator-associated Lung Injury
Serial Daily Diaphragm Ultrasounds in Ventilated Patients
When a person is put on a breathing machine the investigators think that the breathing muscles can get weaker. The investigators are not sure how quickly this happens but in some people this leads to problems when they try to…
- Trial name
- NCT02174029
- Testing
- Ventilation- mandatory, Ventilation- voluntary mode only, Voluntary with preceding mandatory
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- Steve Reynolds
Peripheral Artery Disease, Claudication, Intermittent
Passive Calf Stretching Therapy in Peripheral Artery Disease
The goal of this clinical trial is to assess the effects of passive calf muscle stretching in patients diagnosed with peripheral artery disease (PAD). The main question it aims to answer are: 1.
- Trial name
- NCT06041880
- Testing
- Passive calf muscle stretching device
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Penn State University
Erectile Dysfunction
Pelvic Floor Muscle Training in the Treatment of Erectile Dysfunction
Erectile dysfunction affects about 40% of all men above the age of 40 and the prevalence increases with increasing age. It is not possible to cure the condition as current forms of treatment are aimed solely at improving…
- Trial name
- NCT05385822
- Testing
- Pelvic Floor Muscle Training
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Temporomandibular Joint, Temporomandibular Joint Dysfunction Syndrome
Effects of Masseter Manual Therapy on Temporomandibular Dysfunction
Muscles and myofascial dysfunction are more often the mechanism and source of pain in oral fascial disorders (OFD) than the TMJ.
- Conditions
- Temporomandibular Joint, Temporomandibular Joint Dysfunction Syndrome, Temporomandibular Joint Disorder
- Trial name
- NCT00870922
- Testing
- Active release techniques
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Logan College of Chiropractic
Anorexia Nervosa, Exercise
Training Intervention in the Treatment of Anorexia Nervosa
The scope of the STRONG_2 project is to investigate the effect of supervised exercise as add-on to standard of care (SOC), for patients with eating disorders (EDs).
- Trial name
- STRONG_2 (NCT04185727)
- Testing
- Supervised strength training
- Where
- 2 sites in Denmark
- Volunteers
- 5 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Temporomandibular Joint Disorders, Extracorporeal Shockwave Therapy
Effects of Focal Extracorporeal Shock Wave Therapy in the Treatment of Temporomandibular Disorders of Muscular Origin
The objective of the study is to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in improving pain in patients with TMD pain after 5 weeks of treatment, 1 month and 3 months after the end of treatment.
- Trial name
- NCT05907239
- Testing
- Focused Extracorporeal Shockwave Therapy
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Cancer Survivors, Healthy Participant
A Study to Evaluate the Effects of the Combination of GI-102 With GIB-7 on Biomarkers of Aging in Healthy Adults and Cancer Survivors
This Phase 2a clinical study (GIANTS-1) aims to evaluate a novel dual-combination strategy using GI-102 and GIB-7 to address key pathological features of aging, including immunosenescence (the aging of the immune system)…
- Conditions
- Cancer Survivors, Healthy Participant, Elderly
- Trial name
- GIANTS-1 (NCT07363057)
- Testing
- GI-102 in combination with GIB-7
- Where
- 2 sites in Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- GI Innovation, Inc.
Duchenne Muscular Dystrophy
Sleep Intervention in Young Boys with Duchenne Muscular Dystrophy
This project will systematically plan and evaluate the implementation of the Transdiagnostic Sleep and Circadian Intervention for youth (TranS-CY).
- Trial name
- DMD (NCT04529707)
- Testing
- Transdiagnostic Behavioral Sleep Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Pittsburgh
Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome
Effects of Radial Shock Wave Therapy in the Treatment of Temporomandibular Joint Syndrome.
The aim of this study is to assess the effects of radial shock wave therapy in the treatment of temporomandibular joint syndrome.
- Trial name
- NCT04477122
- Testing
- Manual therapy and extracorporeal radial shock waves therapy
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- University of Jaén
Temporomandibular Disorders, Headache
Temporomandibular Dysfunction Affects Neck Disability, Headache, Anxiety, And Sleep Quality In Women: A Cross-Sectional Study
The temporomandibular joint (TMJ), is the only movable joint between the joints in the head and neck system. It is a component of the chewing system and is involved in important functions such as speech, swallowing, taste and…
- Conditions
- Temporomandibular Disorders, Headache, Neck Disorder, Anxiety
- Trial name
- NCT04948320
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Diaphragm Issues, Mechanical Ventilation Complication
Diaphragm Atrophy and Dysfunction in Mechanical Ventilation
The gold standard of twitch transdiaphragmatic pressure recordings would ultimately clear the fog around the rate of development of Ventilator induced Diaphragm Dysfunction (VIDD) in mechanically ventilated patients over time.
- Conditions
- Diaphragm Issues, Mechanical Ventilation Complication, Respiratory Failure, Intensive Care (ICU) Myopathy
- Trial name
- DAM (NCT05211661)
- Testing
- Respiratory Muscle Testing
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- RWTH Aachen University
Sacroiliac Joint Dysfunction
Muscle Energy Techniques and Sacral Manipulation on Pain, Functional Disability and Quality of Life
The study will be randomized clinical trial. This study will be conducted in University of Lahore Teaching Hospital, Lahore, Pakistan.
- Trial name
- NCT05018780
- Testing
- Muscle Energy Technique, Sacral Manipulation
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- University of Lahore