Clinical trials: Muscle Dysfunction
Temporomandibular Disorder, Pathophysiology
Consequences of Temporomandibular Disorder on Balance Control
To evaluate the effects of the temporomandibular disorder (TMD) and its therapeutic care on postural control in somato-sensory and visual sensitization compared to control subjects matched on age, sex and lifestyle.
- Conditions
- Temporomandibular Disorder, Pathophysiology, Therapy
- Trial name
- DAM (NCT03283839)
- Testing
- Posturography
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Duchenne Muscular Distrophy (DMD)
Endomysial Fibrosis, Muscular Inflammatory Response and Calcium Homeostasis Dysfunction in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is the most common and devastating form of muscular dystrophy, caused by an X-chromosome gene mutation resulting in the absence of the protein dystrophin.
- Trial name
- NCT01823783
- Testing
- Muscle biopsy
- Where
- 7 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Mild Pelvic Floor Dysfunction
Effect of an Abdominal Hypopressive Technique Program on Pelvic Floor Muscles and Urinary Incontinence in Women
Abdominal hypopressive technique (AHT) is a therapy created for the treatment of the pelvic floor dysfunctions in the postpartum.
- Trial name
- UVa_1 (NCT02212418)
- Testing
- Abdominal hypopressive technique
- Volunteers
- 42 people
- Sponsor
- Rafael J. Curbelo
Cervical Cancer, Postoperative Bladder Dysfunction
Transcutaneous Electrical Nerve Stimulation in Nerve-Sparing Radical Hysterectomy: Effects on Bladder Management and Quality of Life in Cervical Cancer
To evaluate the effects of transcutaneous electrical nerve stimulation (TENS) on bladder management, pelvic floor muscle strength, and quality of life (QoL) in patients undergoing nerve-sparing radical hysterectomy (NSRH) for…
- Conditions
- Cervical Cancer, Postoperative Bladder Dysfunction, Urinary Retention, Pelvic Floor Muscle Weakness
- Trial name
- NCT07070687
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Fudan University
Temporomandibular Disorder, Forward Head Posture
Additional Effect of Forward Head Posture Correction on Temporomandibular Dysfunction
The goal of this clinical trial is to test the additional correction effect of nerd neck on damaged jaw in people who suffers from jaw problems and nerd neck at the same time.
- Trial name
- NCT06156345
- Testing
- Conservative with Denneroll, Conservative
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 42 people
- Sponsor
- Shima Abdollah Mohammad Zadeh
Hip Fractures
Hip Abductor Muscle Dysfunction After Nailing of Proximal Femoral Fractures, Incidence and Contributing Factors.
Proximal femoral fractures(PFFs) are common with advancing age. Proximal femoral nail (PFN) is now increasingly used to fix unstable fractures.
- Trial name
- NCT04311892
- Testing
- EMG of the hip abductor muscles
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- South Valley University
Hemiplegia, Stroke
Mirror vs Virtual Reality Therapy for Upper Extremity Function in Hemiplegic Patients
Upper extremity impairment in hemiplegic patients significantly impacts daily activities and reduces quality of life. Although traditional rehabilitation methods can help, some patients experience limited progress.
- Conditions
- Hemiplegia, Stroke, Upper Extremity Dysfunction
- Trial name
- NCT07018336
- Testing
- Mirror Therapy, Virtual Reality (VR) Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istinye University
Chronic Neck Pain, TMD
Additive Effects of Dental Bite Pads During Gymnastic Exercises for the Relief of Chronic Non-specific Neck Pain in Working Women and Men at a VDU Workplace
The study which includes 52 participants suffering from chronic neck pain, determines additional effects of dental bite pads on neck pain and function when performing a 3-month gymnastics programme.
- Conditions
- Chronic Neck Pain, TMD, Temporomandibular Dysfunction
- Trial name
- NCT05302466
- Testing
- gymnastics plus silicon dental bite pad, gymnastics only
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Chronic Temporomandibular Disorders (TMD)
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
Temporomandibular disorders (TMDs) involve a range of conditions with varied causes, affecting a large portion of the U.S. population and posing challenges for diagnosis and management, especially in chronic cases.
- Trial name
- TMD-CPM (NCT06617494)
- Testing
- Pain modulation testing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hematologic Diseases, Chronic Myeloid Leukemia
Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant
PURPOSE: To investigate the effect of the disease and HSCT on muscle dysfunction and to investigate the prognostic role of muscle dysfunction at critical decision points in patients with hematological diseases referred to…
- Conditions
- Hematologic Diseases, Chronic Myeloid Leukemia, Acute Myeloid Leukemia, Acute Lymphoid Leukemia
- Trial name
- NCT04167683
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 144 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Upper Extremity Dysfunction
Movement Enhancing Device for Children
The purpose of this study is to assess: 1) how infants move their bodies to explore, play, and solve problems, 2) if this is different in a high-risk group of infants, and 3) if these abilities can be advanced in a high-risk…
- Trial name
- NCT01959581
- Testing
- Movement Enhancing Device
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Rectal Cancer, Low Anterior Resection Syndrome
The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal Cancer
This randomized controlled trial aims to evaluate the effects of combining Kegel exercise with a single biofeedback session on bowel function, emotional distress, and quality of life in patients who have undergone low anterior…
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, LARS - Low Anterior Resection Syndrome
- Trial name
- BFT in LARS (NCT07253298)
- Testing
- Kegel Exercise with Biofeedback, Kegel Exercise Only
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- National Taiwan University Hospital
Temporomandibular Disorder
Assessment of the Efficacy of a Sensorimotor Approach After Maximum Three Sessions in Subjects With TMD With Hypertonia
The study aims to demonstrate the efficacy of the sensorimotor approach developed by A. Piron (taught to the patient in three sessions) regarding three parameters related to TMD: facial pain, functional incapacities and…
- Trial name
- NCT02632643
- Testing
- Sensorimotor education with a view to obtaining an optimal FWS further to the relaxation of the masticatory, lingual and labial system. Learning of mandibular micro-movements in 5 directions.
- Where
- 6 sites in Belgium, France and 1 more
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Osteovox
Rheumatoid Arthritis, Insulin Resistance
Skeletal Muscle Dysfunction in Rheumatoid Arthritis (RA)
Muscle strength helps determine a person's quality of life and functional independence. Patients with rheumatoid arthritis often suffer from muscle weakness and a pre-diabetic condition called insulin resistance.
- Trial name
- NCT02535832
- Testing
- Pioglitazone
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Gynecologic Cancer
Identification and Prevention of Pelvic Floor Dysfunction in Gynecologic Cancer Survivors
The two goals of this study are to establish a standardized method of assessing the pelvic floor for patients undergoing pelvic radiation and to determine the feasibility of inverse-RT planning using MRI to identify dosimetric…
- Trial name
- NCT05769062
- Testing
- Single digit pelvic exam
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Washington University School of Medicine
Sacroiliac Joint Dysfunction
Effects of Stecco Fascial Manipulation Versus Muscle Energy Technique on Pain Pressure Threshold, Range of Motion and Disability Among Patients With Sacroiliac Joint Dysfunction
This study holds significant importance as it directly addresses the need for effective physiotherapy interventions in patients with sacroiliac joint dysfunction, a condition that contributes substantially to lower back pain and…
- Trial name
- NCT07723014
- Testing
- Stecco fascial manipulation, Muscle energy technique
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
ME/CFS, Long COVID
LIFT: Life Improvement Trial
The LIFT will be conducted at Brigham and Women's Hospital (BWH) of Harvard Medical School, focusing on the effect of Pyridostigmine (Mestinon) and Low-Dose Naltrexone (LDN) in subjects aged 18-70 meeting the Canadian consensus…
- Conditions
- ME/CFS, Long COVID, PASC
- Trial name
- LIFT (NCT06366724)
- Testing
- Pyridostigmine, Low-Dose Naltrexone
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Brigham and Women's Hospital
Dyspareunia, Pelvic Pain
Electrolysis Technique vs Manual Therapy in Pelvic Pain
Pelvic floor muscle physical therapy is recommended in clinical guidelines for women dyspareunia and pelvic pain. This study compare pelvic floor manual therapy and intratissue percutaneous electrolysis (EPI) technique in the…
- Conditions
- Dyspareunia, Pelvic Pain, Pelvic Floor Disorders, Musculoskeletal Pain
- Trial name
- NCT03163160
- Testing
- Pelvic floor manual therapy group, Pelvic floor electrolysis group
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Quirón Madrid University Hospital
Coginitive Dysfunction, Compensated Liver Cirrhosis
Examining the Effects of Different Resistive Exercise Programs in Individuals With Compensated Liver Cirrhosis
Reasons such as sleep disorders, depression, decreased independence in daily living activities and decreased quality of life, which are seen in the majority of liver cirrhosis patients, can cause cognitive dysfunction, especially…
- Conditions
- Coginitive Dysfunction, Compensated Liver Cirrhosis, Physical Dysfunction, Sarcopenia
- Trial name
- NCT06749340
- Testing
- Assigned Interventions, Face-to-face Exercise, Home-based Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bahçeşehir University
Posterior Shoulder Tightness
The Effects of Eccentric-focused Exercise on Posterior Shoulder Tightness in Symptomatic Overhead Athletes
The aim of this study is to investigate the effects of shoulder eccentric exercise training on shoulder mobility, rotator cuff strength, pain and dysfunction, scapular kinematics and muscle activation in symptomatic overhead…
- Trial name
- NCT05305196
- Testing
- Eccentric-focused exercises, Stretching exercises, Hot pack
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University