Clinical trials: Muscle Dysfunction
Mild Cognitive Impairment (MCI)
Effect of Inspiratory Muscle Training in Cognition
The goal of this clinical trial is to examine the effect of a respiratory muscle strengthening program on the cognitive and physical functioning of patients with neurocognitive disorders (Mild Cognitive Impairment) or those…
- Trial name
- NCT07146373
- Testing
- Inspiratoty Muscle training, Usual Care
- Where
- Greece
- Volunteers
- 76 people
- Sponsor
- University of West Attica
Temporomandibular Dysfunction (TMD)
Cervical Proprioception, Masticatory Pain Threshold and Craniovertebral Angle in TMD
Temporomandibular disorder (TMD) is a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures of the head, neck, and cervical region.
- Trial name
- NCT07681570
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Cancer Related Fatigue, Fatigue Syndrome, Chronic
Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue (CFS/ME)
Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue Syndrome (CFS/ME) by Lipidomics, Metabolomics, Intestinal and Peritoneal Microbiome Analysis and Exome Analysis and Investigation of a Possible…
- Trial name
- IMPROFA (NCT03773003)
- Testing
- Probiotics
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Temporomandibular Joint Dysfunction
Manual Therapy and Kinesio Taping on Temporomandibular Joint Dysfunction Following Oral Surgeries
Oral surgeries include various types such as impacted wisdom tooth surgery, oral cyst enucleation (cystectomy), surgical incision and drainage of odontogenic abcess, oral tumor excision and open reduction and internal fixation of…
- Trial name
- NCT05422703
- Testing
- Kinesio tape, Gauze pack, ice pack
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Physical Inactivity, Vascular Dysfunction
Heat Therapy During Reduced Physical Activity
The purpose of this randomized controlled trial is to determine whether daily Finnish dry sauna therapy attenuates the adverse cardiovascular, muscular, and metabolic effects of seven days of experimentally reduced physical…
- Conditions
- Physical Inactivity, Vascular Dysfunction, Skeletal Muscle Atrophy
- Trial name
- HEAT-RPA (NCT07847424)
- Testing
- Sauna, Reduced Physical Activity
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Aging, Cognitive Decline
Augmented Reality Treadmill Walking for Cognitive and Physical Health in Older Adults
This study evaluated the feasibility and health effects of using augmented reality (AR) treadmill walking in older adults. Sixty community-dwelling adults aged 65 to 80 years were randomly assigned to either an AR treadmill group…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Mobility Limitation
- Trial name
- ART-Walk (NCT07074613)
- Testing
- Traditional Treadmill Walking, JOHNSON 8.1T treadmill with Passport AR system
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan College of Performing Arts
Congenital Torticollis, Positionnel Skull Deformation
3D Characterisation of the Skull Base Deformation in Congenital Muscular Torticollis
The congenital muscular torticollis (CMT) is defined by an abnormal posture of the head and the neck compared to shoulders' level of the newborn.
- Trial name
- NCT04421898
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Gynecologic Cancer, Pelvic Floor Disorders
Pelvic Floor Dysfunction and Aerobic Training in Gynecological Cancer
The incidence of gynecological cancer and the related death rates in the world are increasing every year. Unfortunately, pelvic floor disorders (PFDs) such as pelvic pain, dyspareunia, vaginal stenosis, and urinary incontinence…
- Conditions
- Gynecologic Cancer, Pelvic Floor Disorders, Aerobic Exercise
- Trial name
- NCT06406322
- Testing
- PFMT, Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Atılım University
Fatigue, Dyspnea
TaiChi-DTx for Treating Long Covid Symptoms
The randomized controlled trial will be conducted to evaluate the effectiveness of a Multi-domain Tai Chi Digital Therapy for treating the individuals suffering from the long term COVID-19 syndrome (Long COVID).
- Conditions
- Fatigue, Dyspnea, Cognitive Impairment, Muscle Pain
- Trial name
- TaiChi-DTx (NCT05419219)
- Testing
- the multi-domain Tai Chi Digital therapy Software Application
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tim Shi
Muscle Soreness
Effects of Ginger on Muscle Soreness and Dysfunction Stemming From Downhill Running
The objective of the study is to determine whether five days of ginger (Zingiber officinale) supplementation is effective at reducing muscle soreness and improving muscle function following downhill running.
- Trial name
- NCT03028454
- Testing
- Ginger Root
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Multisystemic Smooth Muscle Dysfunction Syndrome, ACTA2
A Retrospective and Prospective Natural History of Genetic Vasculopathies
This study will combine retrospective review of medical records from patients with ACTA2 and ongoing collection of clinical data using standardized instruments and intervals on an observational basis from patients with ACTA2.
- Trial name
- NCT06552052
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Aging, Foot Muscle Dysfunction
Effects of Rehabilitative Exergame Training on Foot Muscle Activity, Balance, and Mobility in Older Adults
This study is designed as a randomized controlled trial. A total of 40 healthy older adults residing in private and public nursing homes and rehabilitation centers in Mersin will be enrolled.
- Conditions
- Aging, Foot Muscle Dysfunction, Sarcopenia, Age-Related Muscle Weakness
- Trial name
- EXG-FOOT (NCT07357662)
- Testing
- Exergame-based Balance and Foot Muscle Training, Conventional Functional Balance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tarsus University
ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis
ME/CFS Brain Fog: Cognitive Rehabilitation Trial
The purpose of this study is to compare two approaches to cognitive rehabilitation in adults with post-viral cognitive syndrome, which resulted in brain fog.
- Conditions
- ME/CFS, ME/CFS Following EBV-associated Infectious Mononucleosis, ME/CFS Following COVID-19, Chronic Fatigue
- Trial name
- NCT07523113
- Testing
- Processing Speed Training, In-session Instrumental Activities of Daily Living Training, Transfer Package
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Anorexia Nervosa, Exercise
Training Intervention in the Treatment of Anorexia Nervosa
The scope of the STRONG_2 project is to investigate the effect of supervised exercise as add-on to standard of care (SOC), for patients with eating disorders (EDs).
- Trial name
- STRONG_2 (NCT04185727)
- Testing
- Supervised strength training
- Where
- 2 sites in Denmark
- Volunteers
- 5 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Temporomandibular Joint Dysfunction
A Comparison of Arthrocentesis, Arthroscopy and Arthroplasty in the Treatment of Temporomandibular Joint Dysfunction
Many patients suffer from a disorder known as temporomandibular joint dysfunction. This disorder has jaw joint pain and limited function as key elements.
- Trial name
- TMJ (NCT00636727)
- Testing
- arthrocentesis, arthroscopy, arthroplasty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Mandibular Dysfunction
Intramuscular Injections of Botulinum Toxin in Lateral Pterygoid Muscle in the Treatment of Temporomandibular Dysfunctions: Studying the Interest of MRI Guidance and Ultrasound Guidance
The main hypothesis is that a significant pain improve (measured with Visual Analogic Scale [VAS]) can be observed after injection of botulinum toxin A, meaning the success of the guidance device.
- Trial name
- MAUSBOT (NCT04900324)
- Testing
- MRI guidance, Ultrasound guidance
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Lung Neoplasm, Survivorship
Assessment of Functional Capacity, Pain, Cognitive and Respiratory Functions in Lung Cancer Survivors
Serious side effects occurs with disease and treatments in survival after lung cancer. For this reason, functional capacity, cognitive status, pain perception and respiratory functions may be affected in lung cancer.
- Trial name
- NCT04431921
- Testing
- Functional capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Skeletal Muscle Ischemia, Severe Lower Limb Ischemia
Protective Effects of L-arginine During Reperfusion by Femoropopliteal Bypass for Lower Limb Ischemic Syndrome in Humans
The symptoms and severity of arterial disease is secondary to perfusion deficit. The specific alteration of the mitochondrial function of ischemic skeletal muscle plays an important role, and therapeutic enhancing mitochondrial…
- Conditions
- Skeletal Muscle Ischemia, Severe Lower Limb Ischemia, Mitochondrial Dysfunction
- Trial name
- NCT02117206
- Testing
- L-arginine (L-arginine Veyron), Nacl
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Peripheral Muscle Dysfunction, COPD
Muscle Training Induced Angiogenesis in COPD
COPD patients experiment a peripheral muscle dysfunction which impact their exercise tolerance and health-related quality of life. The capillary to fiber interface is reduced and impact the exercise capacity of the patients.
- Trial name
- COPDµvasc (NCT02040363)
- Testing
- Muscular biopsy, 5-10 weeks sport training
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Diabetic Peripheral Neuropathy
Effect of High Tone External Muscle Stimulation on Peripheral Arterial Disease
to investigate the effect of high tone external muscle stimulation (HTEMS) on endothelial dysfunction and walking parameters in peripheral vascular disease.
- Trial name
- NCT04555876
- Testing
- high tone external muscle stimulation- stationary bicycle
- Volunteers
- 60 people
- Sponsor
- Cairo University