Clinical trials: Muscle Dysfunction
Premature (Early) Ejaculation, Ejaculatory Dysfunction
Extracorporeal Magnetic Innervation Plus Pelvic Floor Muscle Training for Premature Ejaculation
This single-center, prospective, parallel-group randomized controlled trial evaluated whether extracorporeal magnetic innervation (ExMI) added to pelvic floor muscle training (PFMT) improves pelvic floor muscle function and…
- Conditions
- Premature (Early) Ejaculation, Ejaculatory Dysfunction, Sexual Dysfunction Male
- Trial name
- NCT07385222
- Testing
- Pelvic Floor Muscle Training, Extracorporeal Magnetic Innervation
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Abant Izzet Baysal University
Sacroiliac Joint Dysfunction
Effects of Pelvic Floor Exercises and Muscle Energy Techniques on Pain and Disability in Sacroiliac Joint Dysfunction
This clinical trial aims to evaluate whether combining pelvic floor exercises with muscle energy techniques provides greater improvement in pain and functional disability in adults with sacroiliac joint dysfunction compared to…
- Trial name
- NCT07275294
- Testing
- Muscle Energy Techniques with Hot pack and Transcutaneous Electrical Nerve Stimulation, Muscle Energy Techniques with Hot pack, Transcutaneous Electrical Nerve Stimulation and Pelvic floor Exercises
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Lahore University of Biological and Applied Sciences
COVID-19, Muscle Atrophy
Electrical Stimulation for Critically Ill Post-Covid-19 Patients
Unfortunately, hospital-acquired weakness is highly prevalent among COVID-19 hospitalized patients, who often require prolonged bed-rest or paralytics for an extended period of time in order to maintain oxygenation.
- Conditions
- COVID-19, Muscle Atrophy, Muscle Weakness
- Trial name
- Phase II (NCT05198466)
- Testing
- Electrical Stimulation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Baylor College of Medicine
Temporomandibular Disorder (TMD)
Turkish Version of Helkimo Clinical Dysfunction Index
This study aimed to translate the Helkimo Clinical Dysfunction Index (HCDI) into Turkish and to test its validity and reliability as an outcome measurement method in individuals with temporomandibular dysfunction (TMD).
- Trial name
- NCT07371143
- Testing
- Turkish Version of Helkimo Clinical Dysfunction Index and Accompanying Scales
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Sevgi Medical Center
Endothelial Dysfunction, Disorder of Smooth Muscle
The Effect of a Diabetic- and a Kidney-like Environment on Gene and Protein Expression in Cultured EC and SMC
This research is NOT part of an interventional trial, however the investigators use umbilical cord after birth for isolating endothelial and smooth muscle cells for academic research.
- Trial name
- NCT01423279
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Chronic Obstructive Pulmonary Disease, COPD
Antioxidants and Pulmonary Rehabilitation in COPD Patients
On the basis of published data and investigators results indicating that systemic redox in balance may contribute to the peripheral muscle dysfunction in COPD patients, the investigators propose a study testing the effects of…
- Trial name
- AREB-1 (NCT01942889)
- Testing
- Antioxidant Supplementation associated to Comprehensive respiratory Rehabilitation Program
- Where
- 2 sites in France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Montpellier
Chronic Obstructive Pulmonary Disease
Muscle Dysfunction in Patients With Chronic Obstructive Lung Disease (COPD): the Role of Sympathetic Activation
The objective of the project is to better understand the causes of exercise limitation, dyspnea and neurohumoral activation in patients with COPD.
- Trial name
- NCT01750489
- Testing
- non-invasive ventilation (NIV)
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Obesity & Overweight, Inflammation
Assessment of Respiratory Dysfunction in Obesity and the Use of IMT.
The aim of the project will be to assess the functional condition of the respiratory tract and inflammation resulting from obesity, as well as the possibility of using inspiratory muscle training as a factor reducing the…
- Conditions
- Obesity & Overweight, Inflammation, Ventilation Disorders
- Trial name
- IMT (NCT07307417)
- Testing
- inspiratory muscle training
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Premature (Early) Ejaculation
Dual-Site Botulinum Toxin Type A Injection for Lifelong Premature Ejaculation
Premature ejaculation is a common sexual condition that can cause distress for men and their partners. Different treatments are available, but some men do not respond well to standard therapies.
- Trial name
- DUAL - PE (NCT07426640)
- Testing
- BoNT-A
- Where
- Saudi Arabia
- Volunteers
- 150 people
- Sponsor
- Al Mouwasat Hospital
Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome
Arthrocentesis Versus Botulinum Toxin Injection in Patients With Temporomandibular Joint Disorders: A Randomized Controlled Trial
The goal of this clinical trial is to learn if arthrocentesis works as well as botulinum toxin (Botox) injection to treat pain and jaw dysfunction in adults with temporomandibular joint (TMJ) disorders.
- Conditions
- Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Facial Pain
- Trial name
- RCT (NCT07736521)
- Testing
- Arthrocentesis, Botulinum Toxin-A
- Volunteers
- 66 people
- Sponsor
- Mudher MB Alsunbuli
Fibromyalgia, Cognitive Impairment
Cognitive and Memory Function in Patients With Fibromyalgia
Patients suffering from Fibromyalgia will be examined for the presence of memory and/or cognitive impairment using specific psychological tests.
- Trial name
- NCT00789178
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Myofascial Trigger Point Pain
Integrated Neuromuscular Inhibition Technique and Myofascial Release on Cervical Range of Motion and Dysfunction
to findout the improvement by Integrated Neuromuscular Inhibition Technique and Myofascial Release on Cervical Range of Motion and Dysfunction
- Trial name
- NCT05816161
- Testing
- Integrated Neuromuscular Inhibition Technique, Myofascial Release
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Superior University
Fibromyalgia, Autonomic Dysfunction
Association Between Autonomic Dysfunction and Choroidal Vascularity Index in Fibromyalgia
Fibromyalgia is frequently accompanied by autonomic nervous system dysfunction, often characterized by sympathetic predominance.
- Trial name
- NCT07345546
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Intensive Care (ICU) Myopathy, Functional Disturbance
Intra and Inter Reliability and Validity of the Turkish Version of Ottowa Sitting Scale in Intensive Care Unit Survivors
Introduction-Objective: Balance evaluation is one of the most important components of physical examination. Studies on equilibrium assessment in different research groups; It includes measurements that assess the seating balance…
- Trial name
- NCT03936920
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Izmir Katip Celebi University
Cystic Fibrosis, Mucoviscidosis
Assessment of Quadriceps Muscle Electrostimulation Used in Patients Suffering From Cystic Fibrosis
This is an add-on, randomized, open label, clinical trial that evaluates the use of quadriceps electrostimulation as an additional retraining procedure in patients suffering from cystic fibrosis.
- Trial name
- STIMUCO (NCT00391703)
- Testing
- Electrostimulation programme: using a cycloergometer, Usual sport activity
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Temporomandibular Disorder
INVESTIGATION AND COMPARISON OF THE EFFECTS OF POSTURE EXERCISES ON DYSFUNCTION, POSTURE AND BALANCE IN INDIVIDUALS WITH POSTERIOR EDENTULOUS AND FULL-TOOTHED TEMPOROMANDIBULAR DISORDER
The aim of this study is to investigate the relationship between neck posture and balance in patients with posterior edentulous and full-toothed temporomandibular disorder and to compare the effectiveness of the physiotherapy…
- Trial name
- NCT05704998
- Testing
- Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Dokuz Eylul University
Type 2 Diabetes Mellitus
Role of Allopurinol on Oxidative Stress and Mitochondrial Alterations in Skeletal Muscle of Diabetic Patients
Our recent data in mice have demonstrated a key role of xanthine oxidase in hyperglycemia-induced by Reactive oxygen species production, and a preventive role of allopurinol (inhibitor of xanthine oxidase) on the keeping of…
- Trial name
- DIAXO (NCT02533648)
- Testing
- 2 capsules of allopurinol 150 mg daily for 3 month, 2 capsules of lactose daily for 3 month
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Hospices Civils de Lyon
Severe Sepsis, Septic Shock
Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis
The primary aim of the study is to demonstrate that mitochondrial dysfunction occurs in both skeletal muscle and circulating platelets of severely septic and septic shock ICU-admitted patients.
- Trial name
- NCT00541827
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Cerebral Palsy, Temporomandibular Disorder (TMD)
TMJ Dysfunction and Motor Severity in Children With CP
This study aims to examine the function of the temporomandibular joint (TMJ)-the jaw joint-in children with cerebral palsy (CP).
- Trial name
- NCT07043517
- Testing
- RDC/TMD
- Where
- Turkey (Türkiye)
- Volunteers
- 517 people
- Sponsor
- Istanbul Arel University
Heart Failure, Reduced Ejection Fraction
Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.
The purpose of this study was to investigate the effects of initiation of sacubitril/valsartan vs enalapril treatment on objective measures of both waking activity and sleep in subjects with heart failure with reduced ejection…
- Trial name
- AWAKE-HF (NCT02970669)
- Testing
- sacubitril/valsartan (LCZ696), enalapril
- Where
- 23 sites in United States
- Volunteers
- 140 people
- Sponsor
- Novartis Pharmaceuticals