Clinical trials: Muscle Dysfunction
HIV Infections, Lipodystrophy
Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy Syndrome
With the advent of highly active anti-retroviral therapy(HAART), patients with HIV disease are developing a series of metabolic abnormalities including peripheral fat wasting, increase in truncal fat, high serum triglyceride…
- Conditions
- HIV Infections, Lipodystrophy, Insulin Resistance
- Trial name
- NCT00006185
- Testing
- Avandia administration for 6-12 weeks
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Borderline Personality Disorder
Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder
Selegiline is superior to placebo in improving psychological and physical functioning in patients with Borderline Personality Disorder.
- Trial name
- NCT01912391
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mood and Anxiety Research, Inc
Prediabetes
Training Induced Muscle-Adipose EV Communication
This study examines how muscle cells communicate with fat cells through tiny packages called extracellular vesicles (EV) during exercise.
- Trial name
- TIMER2 (NCT07106450)
- Testing
- Acute Resistance Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yuan Wen
Pain, Quality of Life
Protocol Phototherapy Treatment for Fibromyalgia and Temporomandibular Joint Dysfunction
Temporomandibular joint dysfunction is described as a multifactorial disease and can be directly linked to other diseases, being of structural factors of the Stomatognathic System or not, such as fibromyalgia.
- Trial name
- FM and DTM (NCT02279225)
- Testing
- Group Phototherapy, Phototherapy + Physical activity, Physical activity
- Where
- Brazil
- Volunteers
- 61 people
- Sponsor
- University of Nove de Julho
Muscle Dysfunction, Exertional Rhabdomyolysis
Nutritional Prevention of Exertional Muscle Dysfunction
The investigators want to find out whether a choline supplement can protect muscle health in young men with very common genetic vulnerabilities.
- Conditions
- Muscle Dysfunction, Exertional Rhabdomyolysis, Muscle Strength
- Trial name
- MUSREC (NCT01722448)
- Testing
- Choline
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pelvic Floor Disorders
Pelvic Floor Consciousness in Women With Pelvic Floor Dysfunction
The purpose of the study is to compare the efficacy of different modalities of motor learning of pelvic floor muscle contraction in women with pelvic floor dysfunctions, considering the efficacy of the treatment as improving the…
- Trial name
- PFMCON (NCT04334798)
- Testing
- Active exercises of the pelvic floor muscles & Electrostimulation & Biofeedback, Active exercises of the pelvic floor muscles & Biofeedback, Active exercises of the pelvic floor muscles & Transabdominal US Biofeedback
- Where
- 3 sites in Spain
- Volunteers
- 120 people
- Sponsor
- University of Alcala
Chronic Obstructive Pulmonary Disease (COPD), Respiratory Muscle Dysfunction
Multimodal Assessment of NMES Effects on Respiratory and Peripheral Muscles in COPD
The goal of this clinical trial is to learn if targeted neuromuscular electrical stimulation (NMES) can treat respiratory and peripheral muscle weakness in patients with chronic obstructive pulmonary disease (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Respiratory Muscle Dysfunction, Muscle Weakness
- Trial name
- NMES in COPD (NCT07910006)
- Testing
- Neuromuscular Electric Stimulation, Exercise
- Where
- Indonesia
- Volunteers
- 45 people
- Sponsor
- Universitas Padjadjaran
Critical Illness, Post Intensive Care Syndrome (PICS)
Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)
This two-arm, parallel-group randomized clinical trial investigates the effectiveness of an additional telerehabilitation program compared with standard care in patients with Post-Intensive Care Syndrome (PICS).
- Conditions
- Critical Illness, Post Intensive Care Syndrome (PICS), Cardiopathy
- Trial name
- CARDIO-PICS (NCT07599306)
- Testing
- Tele-rehabilitation, Standard of Care
- Where
- Italy
- Volunteers
- 326 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Postpartum
Postural Correction and Lumbar Stabilization vs MET for Postpartum Pain
This randomized clinical trial will evaluate the effectiveness of combined postural correction and lumbar stabilization exercises compared with Muscle Energy Technique (MET) in postpartum women with sacroiliac joint dysfunction…
- Trial name
- NCT07848425
- Testing
- Postural Correction and Lumbar Stabilization Exercises, Muscle Energy Technique (MET)
- Volunteers
- 82 people
- Sponsor
- University of Lahore
Nonsmall Cell Lung Cancer
Skeletal Muscle Atrophy and Dysfunction in Human Cancer
Cancer and its treatment can have profound effects on skeletal muscle, the most well-recognized being atrophy, weakness and diminished oxidative capacity.
- Trial name
- NCT02949076
- Testing
- Exercise
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Vermont
Pelvic Floor Dysfunction
Efficacy of Biofeedback in Women With Pelvic Floor Dysfunction
Recent studies have found that pelvic floor muscle training can relieve pelvic organ prolapse related symptoms. However, the rate of cure or improvement of symptoms with exercise prescription, different compliance of the…
- Trial name
- NCT04036578
- Testing
- A 12-week PFMT bio-assisted surface electromyographic program
- Volunteers
- 83 people
- Sponsor
- Far Eastern Memorial Hospital
Temporomandibular Disorders
Frequency of Occurrence of the Pain Form of Temporomandibular Joint Dysfunction
Temporomandibular joint dysfunction (TMJD) includes disorders of the masticatory muscles in the stomatognathic system, temporomandibular joints and the surrounding structures.
- Trial name
- NCT03736408
- Where
- Poland
- Volunteers
- 334 people
- Sponsor
- Jagiellonian University
Temporomandibular Joint Disorders, Extracorporeal Shockwave Therapy
Effects of Focal Extracorporeal Shock Wave Therapy in the Treatment of Temporomandibular Disorders of Muscular Origin
The objective of the study is to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in improving pain in patients with TMD pain after 5 weeks of treatment, 1 month and 3 months after the end of treatment.
- Trial name
- NCT05907239
- Testing
- Focused Extracorporeal Shockwave Therapy
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Myofascial Trigger Point Pain, Myofascial Pain Syndrome
Acupuncture, Dry Needle and Botox Injection in Management of Patient With Myofascial Pain Dysfunction Syndrome
Evaluating myofascial pain dysfunction symptoms using acupuncture, dry needle and Botox injection using electromyography and visual Analogue Scale on two time intervals at 2 and 6 months after the intervention
- Trial name
- NCT06013644
- Testing
- Acupuncture needle, Dry needle, Botox Injectable Product
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Disorders (TMD), Disc Displacement
Differential Impact of TMJ Disc Displacement and Muscle Disorders on Pain, Function, and Quality of Life in TMD Patients
This study aims to explore the relationship between the position of the temporomandibular joint (TMJ) disc and key clinical outcomes in patients with temporomandibular disorders (TMD).
- Conditions
- Temporomandibular Disorders (TMD), Disc Displacement, Functional Impairment
- Trial name
- DPTMD (NCT06758479)
- Where
- India
- Volunteers
- 100 people
- Sponsor
- King Khalid University
Aging, Blood Pressure
Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise
High blood pressure (BP) is the major modifiable risk factor for cardiovascular diseases (CVD) and related health conditions, particularly among postmenopausal (PM) women.
- Conditions
- Aging, Blood Pressure, Endothelial Dysfunction, Hypertension
- Trial name
- NCT05000515
- Testing
- High-resistance inspiratory muscle strength training, Aerobic exercise
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Pain, Discomfort
Association Among Pain Perception, Severity of Temporomandibular Joint Dysfunction, and Spinal Health in Caregivers of Stroke Individuals
This study aims to examine pain perception, temporomandibular disorder severity and spine health in caregivers of stroke patients.
- Conditions
- Pain, Discomfort, Caregiver, Temporomandibular Disorder
- Trial name
- NCT06052735
- Testing
- Correlation research
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Aging, Cognitive Decline
Blood Flow Restriction and High-intense Resistance Training in Aging: Interactions Between Neuroplasticity and Muscle
BRAIN-M is a randomized controlled trial designed to examine the effects of a single bout or 12 weeks of blood-flow restriction training or high-intensity resistance training on cognitive function, brain health, muscular…
- Conditions
- Aging, Cognitive Decline, Sarcopenia, Frailty
- Trial name
- BRAIN-M (NCT05744167)
- Testing
- BFRT, MDRT
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Trigger Point Pain
Is Masseteric Nerve Block Effective in Myofascial Pain
The aim of the present study was to compare the efficacy of three different treatment methods in the management of myofascial pain: masseteric nerve block (MN), trigger point injection(TrP) with local anesthetic (LA) and dry…
- Conditions
- Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Trigger Point Pain, Local Anesthesia
- Trial name
- NCT04339673
- Testing
- masseteric nerve block, trigger point injection, dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Temporomandibular Joint Disorders, Temporomandibular Disorder
The Association Between Temporomandibular Disorders and Sacroiliac Joint Dysfunction
The aim of this study is to evaluate the relationship between Temporomandibular Disorders (TMD) and Sacroiliac Joint Disfunction (SIJD) and to determine the immediate effect of single-session orofacial manual therapy on SIJD.
- Trial name
- NCT06035341
- Testing
- Orofacial Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Marmara University