Clinical trials: Muscle Dysfunction
Forward Head Posture
Postural Rehabilitation for Visual Dysfunction in Forward Head Posture
This assessor-blinded randomized controlled trial aims to compare the effects of motor control training, sensor-based biofeedback training using a wearable inertial measurement unit, and standardized postural correction exercises…
- Trial name
- NCT07484555
- Testing
- motor control training, Sensor development training group, conventional posture training
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Riphah International University
Temporomandibular Disorders (TMD), Temporomandibular Dysfunction (TMD)
Emotional Release After Trigger Point Needling to Treat Myofascial Pain of the Head and Neck - Prospective Study
Temporomandibular Dysfunction (TMD) as classified by the DC-TMD has a significant psychosocial component referred to as "Axis II".
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Dysfunction (TMD), Temporomandibular Joint and Muscle Disorder
- Trial name
- NCT06912438
- Testing
- Fill out questionnaire
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cachexia, Pancreatic Cancer
Biological Markers in Patients With Pancreatic Cancer Experiencing Weight Loss
RATIONALE: Learning about biological markers in patients with pancreatic cancer and cachexia may help doctors predict patient outcome and may help the study of cancer in the future.
- Trial name
- NCT00899158
- Testing
- immunologic technique, laboratory biomarker analysis, biopsy
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Case Comprehensive Cancer Center
Compartment Syndrome, Compartment Syndrome Nontraumatic Lower Extremity
From Blast Injury to Multicompartment Dysfunction:
Blast injuries can cause swelling and pressure problems in more than one part of the body. This study will review existing medical records of people treated for blast-related injuries to learn how often these problems affect…
- Conditions
- Compartment Syndrome, Compartment Syndrome Nontraumatic Lower Extremity, Compartment Syndrome Traumatic Upper Extremity, Compartment Syndromes
- Trial name
- BLAST-PCS (NCT07911085)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Duchenne Muscular Dystrophy
Safety and Efficacy of P-188 NF in DMD Patients
This is an open-label study to evaluate the safety, tolerability and efficacy of daily, subcutaneous dosing with P-188 NF (Carmeseal-MD™) in non-ambulatory boys with Duchenne Muscular Dystrophy (DMD).
- Trial name
- NCT03558958
- Testing
- P-188 NF
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Phrixus Pharmaceuticals, Inc.
Age-related Cognitive Decline, Age-related Physiology Decline
Brain Aging: Muscle-to-brain Axis Modulates Physio-cognitive Decline
The primary goal is to develop a multidomain intervention program focused on preserving global or regional brain volume and functions while simultaneously improving physical mobility and cognitive functions in older individuals…
- Trial name
- NCT05828043
- Testing
- Multi-domain intervention
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- National Yang Ming Chiao Tung University
Spinal Cord Injury, Spinal Cord Involvement
Clinical Trial of a Serious Game for Individuals With SCI/D
This study will evaluate the efficacy of a newly developed serious game, SCI HARD, to enhance self-management skills, self-reported health behaviors, and quality of life among adolescents and young adults with spinal cord injury…
- Conditions
- Spinal Cord Injury, Spinal Cord Involvement, Spina Bifida, Transverse Myelitis
- Trial name
- NCT02341950
- Testing
- SCI Hard
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- University of Michigan
Elderly Persons
Hypoxia and Exercise in the Elderly
Ageing is the primary risk factor for most chronic diseases including type 2 diabetes mellitus. Sarcopenia and muscular mitochondrial dysfunction with aging are crucial mechanisms leading to decreased exercise tolerance and…
- Trial name
- NCT02196623
- Testing
- Hypoxic exercise, Normoxic Exercise
- Where
- Germany
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Prader-Willi Syndrome
Mitochondrial Complex I Dysfunction in PWS
Prader-Willi Syndrome (PWS) is characterized by profound infantile hypotonia, growth delay, cognitive impairment, muscle weakness and exercise intolerance.
- Trial name
- NCT03831425
- Testing
- Coenzyme Q10
- Where
- Canada
- Sponsor
- The Hospital for Sick Children
Autism Spectrum Disorder, Temporomandibular Joint Disorders
Balance, TMJ, Social Adaptive Assessment in Individuals With Autism Spectrum Disorder
The aim of our study is to evaluate temporomandibular joint (TMJ), cervical posture, balance, dual-task performance, and social adaptation skills in individuals with autism.
- Conditions
- Autism Spectrum Disorder, Temporomandibular Joint Disorders, Postural; Defect
- Trial name
- NCT06721104
- Testing
- Dual Task, Functional Balance, Social Adaptation Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Interstitial Lung Disease With Systemic Sclerosis
Pelvic Floor Dysfunction in Pulmonary Systemic Sclerosis
Systemic sclerosis (SSc) is a heterogeneous multisystem disease characterized by vascular dysfunction, immune abnormalities, and progressive fibrosis of the skin and internal organs.
- Trial name
- NCT07817160
- Testing
- Pelvic Floor Health Knowledge Assessment, Pelvic Floor Dysfunction Assessment, Core Endurance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Biruni University
Pain, Temporomandibular Joint Disorders
Effectiveness of Physiotherapy Treatments in Temporomandibular Joint Dysfunction
The study will determinate the influence of four selected physiotherapeutic procedures on the pain intensity, the bioelectrical activity of the masseter muscle, and the range of mandibular mobility in patients with TMDs…
- Conditions
- Pain, Temporomandibular Joint Disorders, Muscle Hypertonia, Myofacial Pain
- Trial name
- NCT05619380
- Testing
- physiotherapy treatment
- Where
- Poland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Sacroiliac Joint Dysfunction, Muscle Energy Techniques
Comparative Effects of Autogenic Inhibition and Reciprocal Inhibition Technique on Pain, Functional Disability and Gait in Sacroiliac Joint Dysfuction.
Sacro-iliac joint act as the shock absorber of the body. It is responsible for transferring vertical load of the whole body to lower limb hence contributing to stability of pelvic girdle.
- Trial name
- NCT07600359
- Testing
- Autogenic Inhibition, Reciprocal Inhibition
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Fibromyalgia
The Effect of Sympathetic Dysfunction on Muscle Spindle in Fibromyalgia
This study aims to reveal whether there is an impairment in the sympathetic regulation of muscle spindle sensitivity in patients with fibromyalgia syndrome (FMS).
- Trial name
- NCT05704374
- Testing
- sympathetic stimulation maneuver (mental arithmetic test, cold pressure test), Pregabalin 150mg
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Heart Failure, Fatigue; Muscle, Heart
POWER Myocardial Fatigue Study: a Biomechanical Assessment of Contractility of Human Myocardium
To gain a comprehensive understanding of the biomechanical behaviour of human heart to explore the concept of myocardial fatigue in response to a temporal range of preload, afterload and drug-induced inotropy using in-vitro…
- Conditions
- Heart Failure, Fatigue; Muscle, Heart, Myocardial Dysfunction, Exhaustion; Heart
- Trial name
- POWER (NCT04899635)
- Testing
- In-vitro contractile fatigue protocol
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Cognitive Dysfunction, Acquired Brain Injury
Fareon Open Label Device Clinical Trial
The purpose of this study is to assess the safety and feasibility of an at-home MMT treatment in patients with cognitive dysfunction related to acquired brain injury, Long COVID, traumatic brain injury, myalgic encephalomyelitis…
- Conditions
- Cognitive Dysfunction, Acquired Brain Injury, Traumatic Brain Injury
- Trial name
- NCT07600320
- Testing
- Fareon device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Bruxism, Pelvic Floor Disorder
Bruxism and Pelvic Floor Dysfunction in Young Women
Bruxism and Pelvic Floor Dysfunction in Young Women
- Conditions
- Bruxism, Pelvic Floor Disorder, Young Adult Females, Myofascial Pain Dysfunction Syndrome
- Trial name
- NCT07437924
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Diaphragmatic Paralysis
Effects of Inspiratory Muscle Training on Exertional Breathlessness in Patients With Unilateral Diaphragm Paralysis
Treatment options for unilateral diaphragm paralysis are limited. Diaphragmatic plication via mini thoracotomy is sometimes considered in the University Hospital Leuven if severe symptoms persist for longer than 12 months after…
- Trial name
- NCT04563468
- Testing
- Strength inspiratory muscle training, Endurance inspiratory muscle training
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Pelvic Somatic Dysfunction
Unilateral vs Bilateral Application of Muscle Energy Techniques in Pelvic Somatic Dysfunction
The goal of this clinical trial is to compare the efficacy of pelvic muscle energy technique online against the traditional full length osteopathic pelvic treatment protocol.
- Trial name
- PMEOMT (NCT06266650)
- Testing
- Osteopathic Treatment Technique- Muscle Energy Treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Touro College and University System
Temporo-mandibular Dysfunction, Temporomandibular Disorder (TMD)
Temporomandibular Disorder (TMD) Diagnostic Concordance Between Physiotherapist and Surgeon
Jaw disorders is the leading cause in facial pain, affecting many people in the world. Despite many patients finding relief from conservative treatment, many get referred to the surgeon for an evaluation.
- Conditions
- Temporo-mandibular Dysfunction, Temporomandibular Disorder (TMD), Temporomandibular Dysfunction (TMD), Temporomandibular Disorders (TMDs)
- Trial name
- TMD (NCT07560917)
- Testing
- Physiotherapy assessment
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre