Clinical trials: Muscle Dysfunction
Age-related Functional Decline, Mild Cognitive Impairment
Health Benefits of Nutraceutical Supplementation in Older Adults.
This study examines a multi-ingredient nutraceutical designed to support several areas of health in older adults, including muscle strength, cognitive function, immune response, and inflammation.
- Trial name
- NCT07534878
- Testing
- Powder containing whey isolate and herbal extracts (30g sachet)
- Where
- India
- Volunteers
- 23 people
- Sponsor
- GPLIFE HEALTHCARE PRIVATE LIMITED
Cancer Survivors, Healthy Participant
A Study to Evaluate the Effects of the Combination of GI-102 With GIB-7 on Biomarkers of Aging in Healthy Adults and Cancer Survivors
This Phase 2a clinical study (GIANTS-1) aims to evaluate a novel dual-combination strategy using GI-102 and GIB-7 to address key pathological features of aging, including immunosenescence (the aging of the immune system)…
- Conditions
- Cancer Survivors, Healthy Participant, Elderly
- Trial name
- GIANTS-1 (NCT07363057)
- Testing
- GI-102 in combination with GIB-7
- Where
- 2 sites in Australia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- GI Innovation, Inc.
Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome
Effect of Stellate Ganglion Block on ME/CFS
The goal of this clinical trial is to study the effects of stellate ganglion block (SGB) in participants with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Conditions
- Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome, Chronic Fatigue Disorder, Chronic Fatigue and Immune Dysfunction Syndrome
- Trial name
- SGB_ME (NCT05664711)
- Testing
- Bupivacaine Injection
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Neuroversion, Inc.
Temporomandibular Disorder, Forward Head Posture
Additional Effect of Forward Head Posture Correction on Temporomandibular Dysfunction
The goal of this clinical trial is to test the additional correction effect of nerd neck on damaged jaw in people who suffers from jaw problems and nerd neck at the same time.
- Trial name
- NCT06156345
- Testing
- Conservative with Denneroll, Conservative
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 42 people
- Sponsor
- Shima Abdollah Mohammad Zadeh
Healthy
Analysis of Heart Muscle Function Following Exercise in Patients With Heart Disease
This study is designed to examine the blood flow, the nutrition, and the beating function of the heart under different conditions. Patients with narrowed coronary arteries my have restricted blood flow to the heart.
- Trial name
- NCT00001528
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Fibromyalgia
Heart Rate Variability in Fibromyalgia - Effects of Strengthening Exercises
Abstract Objective: Autonomic dysfunction is an important mechanism that could explain many symptoms observed in fibromyalgia (FM).
- Trial name
- NCT02004405
- Testing
- strengthening exercise, flexibility exercise
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of Espirito Santo
Sacroiliac Dysfunction
Global Changes Associated With Sacroiliac Joint Dysfunction
Summary Sacroiliac joint dysfunction (ASI) is an alteration in the normal biomechanics of the joint, which leads to hypomobility or hypermobility of that joint.
- Trial name
- GCASID (NCT06687148)
- Testing
- Manual manipulation
- Where
- Portugal
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Temporomandibular Disorders, Headache
The BETY-Biopsychosocial Questionnaire (BETY-BQ) in Individuals With Temporomandibular Dysfunction-Related Headache
This study investigates the validity and reliability of the BETY- Biopsychosocial Questionnaire (BETY-BQ) as a biopsychosocial assessment tool in individuals with temporomandibular dysfunction-related headaches.
- Trial name
- NCT05902026
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Hasan Kalyoncu University
Myocarditis, ANCA Associated Vasculitis
EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases
Inflammatory Cardiovascular Diseases and Autoimmune Rheumatic Diseases (ICARDs) encompass cardiovascular involvement in connective tissue diseases, vasculitis, and primary inflammatory cardiac processes affecting all layers of…
- Conditions
- Myocarditis, ANCA Associated Vasculitis, Pericarditis, Systemic Sclerosis
- Trial name
- EACVI-INFLAME (NCT07077304)
- Testing
- observational study
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pelvic Floor Muscle Weakness, Postpartum
The Pelvic Floor Muscle Function in Chinese Primipara, a One-year Cohort Study
It is a prospective cohort study.The primiparas in six geographic regions of China are recruited to observe the natural recovery of pelvic floor muscle.
- Conditions
- Pelvic Floor Muscle Weakness, Postpartum, Primiparity
- Trial name
- NCT03506204
- Where
- China
- Volunteers
- 3,120 people
- Sponsor
- Peking Union Medical College Hospital
Congenital Torticollis, Positionnel Skull Deformation
3D Characterisation of the Skull Base Deformation in Congenital Muscular Torticollis
The congenital muscular torticollis (CMT) is defined by an abnormal posture of the head and the neck compared to shoulders' level of the newborn.
- Trial name
- NCT04421898
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Temporomandibular Joint Dysfunction, Myofunctional Therapy
Temporomandibular Joint Respiratory and Thoracic Region Added to Myofunctional Rehabilitation in Dysfunction Comparison of the Effects of Exercises
In the study, a questionnaire form will be applied to the participants using a face-to-face interview technique. Through the questionnaires, demographic characteristics, pain intensity, location of pain, symptoms of dysfunction…
- Conditions
- Temporomandibular Joint Dysfunction, Myofunctional Therapy, Rehabilitation Exercise
- Trial name
- NCT06883825
- Testing
- Myofunctional Therapy, Myofunctional Therapy + Respiratory Exercises, Myofunctional Therapy + Thoracic Region Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Merve Keskin
Fibromyalgia Syndrome
The Effect of Neural Therapy on Heart Rate Recovery, Cardiac Parameters and Pain in Fibromyalgia
Background: Autonomic dysfunction has been observed in patients with fibromyalgia and is associated with symptoms and arrhythmia development in such patients.The investigators can analyze dysautonomia using heart rate recovery…
- Trial name
- NCT06795750
- Testing
- neural therapy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uşak University
Fibromyalgia Syndrome
Transcutaneous Vagus Nerve Stimulation for Pain and Autonomic Dysfunction in Fibromyalgia (RESET-FMS)
Fibromyalgia syndrome (FMS) is a chronic pain condition characterized by widespread pain, fatigue, sleep disturbances, cognitive symptoms, and autonomic dysfunction, significantly impairing quality of life.
- Trial name
- RESET-FMS (NCT07682090)
- Testing
- Transcutaneous Vagus Nerve Stimulation
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Roma La Sapienza
Pelvic Organ Prolapse, Urinary Incontinence
Intelligent Diagnosis and Treatment System for Pelvic Floor Dysfunction in Elderly Women
The aim of this study is to propose an intelligent diagnosis and treatment system for for pelvic floor dysfunction in elderly women.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Diagnosis
- Trial name
- NCT06372340
- Testing
- Personalized pelvic floor rehabilitation program generated by the intelligent diagnosis and treatment system., Standard pelvic floor muscle training(PFMT) program
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Sleep Apnea, Spinal Cord Injuries
Untreated Sleep Apnea as an Aggravating Factor for Other Secondary Medical Conditions After Spinal Cord Injury
This cross-sectional prospective study will assess the potential association of more severe sleep apnea after spinal cord injury with more intense neuropathic pain, more severe spasticity, and more significant cardiovascular…
- Conditions
- Sleep Apnea, Spinal Cord Injuries, Spasticity, Muscle, Neuropathic Pain
- Trial name
- NCT05687097
- Testing
- Home-based sleep screening test or hospital-unattended sleep screening test, Cardiovascular beat-to-beat monitoring, ECG monitoring
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Posterior Tibial Tendon Insufficiency
Low-Level Laser Therapy and Orthotic Insole in Tibialis Posterior Tendon Insufficiency
The purpose of this study is to compare low-level laser therapy and insole interventions on pain, function and muscle strength in subjects with posterior tendon insufficiency.
- Trial name
- NCT03363074
- Testing
- Orthotic Insole, Low-Level Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Sacroiliac Joint Dysfunction
Effects of Intra Muscular Electrotherapy Combined With Manipulative Therapy in Patients With Sacral Torsion
This study is a randomised controlled trial and the purpose of this study is to determine the effect of intra muscular electrotherapy combined with manipulative therapy in terms of pain, mobility, range of motion, and disability."
- Trial name
- NCT06442540
- Testing
- Physical Agents, Manipulation, Core Stability Exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Diabetes Type 2, Frail Elderly Syndrome
Involvement of Muscle Mitochondrial Dysfunction in Frailty in Older Adults. Role of Exercise
This study aims to investigate the role of skeletal muscle mitochondrial dysfunction in the development of frailty in older adults and to evaluate whether a short-term, supervised resistance training intervention can improve…
- Conditions
- Diabetes Type 2, Frail Elderly Syndrome, Mitochondrial Function, Bioenergetics, Functionality
- Trial name
- MITOSTRENGTH (NCT07828847)
- Testing
- Short-duration resistance training
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Neck Pain, Low Back Pain
Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain
The investigators hypothesize that non able-bodied participants with reported acute, sub-acute, or chronic symptoms of neck or back pain of a musculoskeletal origin will have magnetic resonance imaging (MRI), X-ray and blood…
- Trial name
- NCT00134225
- Testing
- Muscle Pattern Recognition (MPR)
- Where
- 4 sites in United States, Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- iTech Medical, Inc.