Clinical trials: Muscle Dysfunction
Erectile Dysfunction Due to Diseases Classified Elsewhere, Covid19
Effects of COVID-19 on Cavernous Smooth Muscle
The aim of the study is to illuminate the role of COVID-19 in the pathophysiology of erectile dysfunction (ED). Nine patients that had COVID-19 and were treated as outpatients were classified as group 1, 10 patients who were…
- Trial name
- NCT04980508
- Testing
- corpus cavernosum electromyography
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Ankara Yildirim Beyazıt University
Mild Cognitive Impairment (MCI), Sarcopenia
Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment
Mild Cognitive Impairment (MCI) in older adults is linked to muscle loss (sarcopenia) and can lead to dementia, with pain further impacting cognitive and physical performance.
- Trial name
- NCT06828926
- Testing
- Tai Chi
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio University
Regional Blood Flow
Dysfunction of Nutritive Blood Flow as a Determinant of Anabolic Resistance in Older People
With age, muscles tend to waste at 0.5-1% per year, so that an 80 year old may have only 70% of the muscle possessed at 50. Muscle loss makes it harder to carry out tasks that require strength, keep the body balanced and continue…
- Trial name
- Dunhill01 (NCT01734616)
- Testing
- Old Exercise, Old Acute Cocoa, Old 7 Day Cocoa
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Temporo-mandibular Dysfunction, Disc Displacement
Effects of Orofacial Myofunctional Therapy and Cervical Stabilization Exercises in Patients With Axis-i Group Iia Temporomandibular Dysfunction
The proposed PhD study, "Effects of Orofacial Myofunctional Therapy and Cervical Stabilization Exercises in Patients with Axis-I, Group II-a Temporomandibular Dysfunction," aims to evaluate an integrated physiotherapy approach…
- Conditions
- Temporo-mandibular Dysfunction, Disc Displacement, Axis I Diagnosis, Disc Displacement With Reduction
- Trial name
- OMT (NCT07853144)
- Testing
- Cervical Stabilization Exercises, Orofacial Myofunctional Therapy
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- University of Lahore
Duchenne Muscular Dystrophy (DMD)
Efficacy and Tolerability of Idebenone in Boys With Cardiac Dysfunction Associated With Duchenne Muscular Dystrophy
Idebenone is a synthetic analogue of coenzyme Q10 and is a powerful antioxidant and essential constituent of the process of energy production on the cellular level.
- Trial name
- DELPHI (NCT00654784)
- Testing
- idebenone
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Santhera Pharmaceuticals
Incontinence, Erectile Dysfunction Following Radical Prostatectomy
Additional Effects of Aerobic and Resistance Exercises to Pelvic Floor Muscle Training After Radical Prostatectomy
In the literature, studies about urinary symptoms after radical prostatectomy (RP) are generally focused on urinary incontinence (UI), and studies about sexual symptoms are focused on erectile dysfunction (ED).
- Trial name
- NCT06126874
- Testing
- Patient Education, Pelvic Floor Muscle Training, Aerobic Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Hacettepe University
Persistent Physical Symptoms (PPS), Functional Disorder
The Pilot of the Turku Outpatient Clinic for Functional and Fatigue Disorders
This study examined 125 working-age patients from the Turku Outpatient Clinic for Functional and Fatigue Disorders. "Patients participate in the clinic's biopsychosocial, multidisciplinary, and individually tailored…
- Conditions
- Persistent Physical Symptoms (PPS), Functional Disorder, Fatigue Syndrome, Chronic
- Trial name
- TOCliFFD (NCT07272148)
- Testing
- Biopsychosocial, multidisciplinary, and individually tailored rehabilitation for patients with persisten symptoms
- Where
- Finland
- Volunteers
- 125 people
- Sponsor
- Turku University Hospital
Temporomandibular Joint Dysfunction Syndrome
Tailored Self-Management of Temporomandibular Disorders (TMD) Using Health Information Technology
The purpose of this pilot project is to determine the feasibility and acceptability of proposed methods for a subsequent clinical trial of a tailored self-management program (PACT) designed to decrease pain in participants with…
- Trial name
- TMDPACT (NCT03036215)
- Testing
- PACT Experimental Arm
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Heart Failure With Preserved Ejection Fraction, Hypertrophic Cardiomyopathy
Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
Heart scarring, also known as fibrosis, plays a major role in a lot of heart muscle abnormalities. These abnormalities of the heart muscle can lead to major issues such as symptoms of heart failure, dangerous heart rhythm…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Hypertrophic Cardiomyopathy, Cardiac Sarcoidosis, Hypertensive Heart Disease
- Trial name
- CHIEFTain (NCT06409585)
- Testing
- 68Ga-FAPI or 18F-AlF-FAPI cardiac PET-MR, Echocardiogram, Cardiac MRI
- Where
- United Kingdom
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Musculoskeletal Injury
Effects of Kinesio-Taping and Muscle Energy Technique on Chronic Sacroiliac Joint Dysfunction
Pregnancy is the main occasion of every woman's life in which numerous episodes of physiological and anatomical adjustments takes place within woman's body to become a mother.
- Trial name
- NCT05442476
- Testing
- Kinesiotaping, Muscle Energy Technique, conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Ziauddin University
Post-Acute COVID-19 Vaccination Syndrome, Postviral Fatigue
Clinical Laboratory Evaluation, Assessment of Symptoms and Recovery in Patients With Post-COVID-19-Vaccination Syndrome
Some people report persistent health problems after receiving the COVID-19 vaccine. These symptoms persist well beyond typical short-term vaccine side effects and are not attributable to any other known medical conditions.
- Trial name
- CLEAR (NCT07400848)
- Testing
- Blood sampling and analysis, The continuous Reactive Hyperemia Index (InRHI) measured by EndoPAT
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bern
Diaphragm Dysfunction, Mechanical Ventilation
A Biobank for Diaphragm Muscular Fiber
This non-interventional study focuses on mechanical ventilation used in intensive care unit to supplement ventilatory function in patients.
- Trial name
- BOTAN (NCT02900300)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Montpellier
Temporomandibular Joint Dysfunction
MASSETER MUSCLE EVALUATION AFTER TEMPOROMANDIBULAR JOINT ARTHROCENTESIS
ULTRASONOGRAPHIC AND ELASTOGRAPHIC EVALUATION OF THE MASSETER MUSCLE AFTER TEMPOROMANDIBULAR JOINT ARTHROCENTESIS
- Trial name
- TMJ (NCT07744100)
- Testing
- TEMPOROMANDIBULAR JOINT ARTHROCENTESIS
- Volunteers
- 50 people
- Sponsor
- sema kaya
Styloid-Stylohoid Syndrome, Temporomandibular Disorder
Evaluation of Styloid Chain Calcification to the Patient With the Temporomandibular Joint Disorder
The aim of the study was to evaluate any relation between elongated styloid process (ESP) and type of Temporomandibular Joint Disorders (TMD).
- Trial name
- NCT04280107
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Nuh Naci Yazgan University
Fibromyalgia Syndrome
Palpitations and Tachycardia in Fibromyalgia Syndrome
Clinically Characterized by the presence of chronic widespread pan and tenderness, Fibromyalgia (FM) is one of the most common "functional" syndromes. FM is currently conceived of as representing a prototype of central pain, i.e.
- Trial name
- NCT01147263
- Testing
- Evaluation of autonomic parameters
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pelvic Floor Disorders
Pelvic Floor Consciousness in Women With Pelvic Floor Dysfunction
The purpose of the study is to compare the efficacy of different modalities of motor learning of pelvic floor muscle contraction in women with pelvic floor dysfunctions, considering the efficacy of the treatment as improving the…
- Trial name
- PFMCON (NCT04334798)
- Testing
- Active exercises of the pelvic floor muscles & Electrostimulation & Biofeedback, Active exercises of the pelvic floor muscles & Biofeedback, Active exercises of the pelvic floor muscles & Transabdominal US Biofeedback
- Where
- 3 sites in Spain
- Volunteers
- 120 people
- Sponsor
- University of Alcala
Type 1 Diabetes
Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1
The proposed study is designed to test the hypothesis that treatment of resveratrol for 12 weeks will improve both endothelin-B receptor (aim 1) and skeletal muscle mitochondrial function (aim 2) in people with type 1 diabetes.
- Trial name
- T-St1M (NCT04449198)
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Augusta University
Postpartum Period, Pelvic Floor Muscle Weakness
Comparative Analysis of Hypopressive Versus Core Stability Exercises in Postpartum Women
The purpose of this study is to compare the effectiveness of Hypopressive exercises versus Core Stability exercises in restoring pelvic floor and abdominal muscle function in postpartum women.
- Conditions
- Postpartum Period, Pelvic Floor Muscle Weakness, Pelvic Floor Dysfunction
- Trial name
- NCT07710911
- Testing
- Hypopressive Exercises
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Lahore
Temporomandibular Joint Dysfunction
A Comparison of Arthrocentesis, Arthroscopy and Arthroplasty in the Treatment of Temporomandibular Joint Dysfunction
Many patients suffer from a disorder known as temporomandibular joint dysfunction. This disorder has jaw joint pain and limited function as key elements.
- Trial name
- TMJ (NCT00636727)
- Testing
- arthrocentesis, arthroscopy, arthroplasty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Parkinsons Disease
First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)
This study is researching an experimental drug called ALN-SNCA (called "study drug"). The study is focused on people with early Parkinson's disease, a disorder of the nervous system that affects movement.
- Trial name
- NCT07216066
- Testing
- ALN-SNCA
- Where
- 3 sites in Canada, Netherlands
- Volunteers
- 46 people
- Sponsor
- Regeneron Pharmaceuticals