Clinical trials: Muscle Fatigue, active
Exercise-Induced Muscle Fatigue, Fatigue Recovery
Acute Effects of High-Intensity Laser Therapy on Pain, Muscle Stiffness, and Grip Strength in Healthy Adults
The goal of this clinical trial is to learn whether high-intensity laser therapy applied before exercise reduces the loss of handgrip strength, muscle stiffness, and pain after a tiring forearm exercise in healthy adults.
- Trial name
- HILT (NCT07895862)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Obesity & Overweight, GLP - 1
A Study on Ubiquinol on Fatigue and Muscle Strength in Healthy Adults Taking GLP-1 Agonists
The goal of this clinical trial is to learn if a daily ubiquinol supplement can reduce fatigue and help maintain muscle strength in adults aged 30-65 who are taking a GLP-1 weight loss medication (Wegovy® or Mounjaro®).
- Conditions
- Obesity & Overweight, GLP - 1, Fatigue Severity Scale, Ubiquinol
- Trial name
- Project Zest (NCT07789106)
- Testing
- Ubiquinol 100 MG Oral Capsule
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- StudySetGo
Muscle Fatigue
Microcurrent Therapy and the Post-Exercise Physiological Response (MENS_PE)
The goal of this clinical trial is to find out whether microcurrent therapy changes blood levels of creatine kinase, a marker of muscle stress, during the first 48 hours after exercise in military personnel.
- Trial name
- MENS_PE (NCT07877337)
- Testing
- Microcurrents Therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Hematologic Malignancies, Hematopoietic Stem Cell Transplantation
Effects of Resistance Training on Recovery During Hematopoietic Stem Cell Transplantation
This study investigates whether a resistance training program can help patients recovering from hematopoietic stem cell transplantation (HSCT) for hematologic malignancies.
- Conditions
- Hematologic Malignancies, Hematopoietic Stem Cell Transplantation, Resistance Training, Neutropenia
- Trial name
- NCT07872813
- Testing
- 8-week Elastic Band Resistance Training Program
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Muscle Fatigue, Functional Electrical Stimulation
Recumbent Cycling and Functional Electrical Stimulation for Lower Limb Rehabilitation
This study evaluates two different control strategies for a rehabilitation device that combines recumbent leg-cycling with functional electrical stimulation (FES) of the quadriceps muscle.
- Conditions
- Muscle Fatigue, Functional Electrical Stimulation, Neuromuscular Rehabilitation
- Trial name
- BiciFES (NCT07873424)
- Testing
- Fatigue-Feedback FES Control Strategy, Standard FES Control Strategy
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue Exercise
This randomized, parallel, placebo-controlled, double-blind clinical trial will evaluate the effects of low-intensity therapeutic ultrasound on muscle recovery after a fatiguing handgrip exercise protocol in healthy adults.
- Trial name
- NCT07871942
- Testing
- Pulsed Low-Intensity Therapeutic Ultrasound
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Muscle Fatigue
Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Consecutive Soccer Trainings in Soccer Players
This is a monocentric study assessing hamstring and quadriceps neuromuscular fatigue after 3 consecutive soccer trainings. The purpose of this study was: 1.
- Trial name
- QIF2 (NCT07861269)
- Testing
- a simulated soccer training
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Running, Athletic Performance
A Multiphase Analysis of Next-generation Trail Footwear
This study will investigate how different advanced-foam trail-running footwear configurations affect running economy, performance, comfort, and fatigue in competitive trail runners.
- Conditions
- Running, Athletic Performance, Oxygen Consumption, Muscle Fatigue
- Trial name
- NEXTGENTRAIL (NCT07855042)
- Testing
- Running footwear
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fernando González-Mohíno Mayoralas
Mental Fatigue, Muscle Strength Dynamometer
Acute Mental Fatigue and Muscle Strength
This study will investigate the acute effects of mental fatigue on lower-extremity muscle strength and limb symmetry in healthy young adults.
- Trial name
- NCT07846618
- Testing
- Computer-Based Mental Fatigue Protocol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Primary Mitochondrial Disease
Natural History Study of Mitochondrial Myopathy
The goal of this observational study is to develop and validate tools to measure disease course in patients with primary mitochondrial myopathy (PMM).
- Trial name
- NCT05250375
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Sport, Muscle Fatigue
Effect of KA-EX Supplementation on Recovery Parameters in High-Level Young Football Players
The purpose of this study is to evaluate the effects of KA-EX supplementation on recovery parameters in elite young football players.
- Conditions
- Sport, Muscle Fatigue, Recovery of Function (G11.427.698.620), Athletic Performance
- Trial name
- Effect of KA-E (NCT07824752)
- Testing
- KA-EX, Experimental: KA-EX Supplement
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Antonio Molina Lopez
Aging, Muscle Atrophy or Weakness
C-Protein in Fatigue and Aging
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
- Conditions
- Aging, Muscle Atrophy or Weakness, Sarcopenia in Elderly, Sarcopenia
- Trial name
- NCT05926219
- Testing
- Fatiguing Exercise
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Local Muscular Endurance and Fatigue, NIRS Skeletal Muscle Mitochondrial Capacity
Near-Infrared Spectroscopy, Acute Taurine Supplementation, and Isolated Muscular Endurance and Fatigue Resistance in Young Healthy Adults
The goal of this clinical trial is to determine the association between near-infrared spectroscopy (NIRS)-derived mitochondrial oxidative phosphorylation (OXPHOS) capacity of the vastus lateralis muscles, and both local muscular…
- Conditions
- Local Muscular Endurance and Fatigue, NIRS Skeletal Muscle Mitochondrial Capacity, Acute Taurine Supplementation
- Trial name
- NCT07654946
- Testing
- Acute Taurine Supplementation
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Photobiomodulation, Fatigue
Photobiomodulation Effects on Fatigue and Muscle Damage Induced by NMES
Neuromuscular electrical stimulation (NMES) is widely used to improve muscle strength and mitigate atrophy. However, its clinical efficacy is often limited by early neuromuscular fatigue, muscle damage, and discomfort, which…
- Conditions
- Photobiomodulation, Fatigue, Discomfort, Electrical Stimulation
- Trial name
- NCT07602933
- Testing
- Active Photobiomodulation, NMES-evoked fatigue protocol
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Cognition, Inflammation Biomarkers
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Inflammation Biomarkers, Bone Metabolism Biomarkers, Fatigue Symptom
- Trial name
- NCT07740967
- Testing
- Collagen peptides and omega-3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Cognition, Muscle Strength
Dietary Supplements and Middle Aged Women (Creatine)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Muscle Strength, Fatigue Symptom, Blood Pressure and Augmentation Index
- Trial name
- NCT07729930
- Testing
- Creatine Monohydrate
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Muscle Fatigue, Exertion, Perceived
The Influence of Passive Local Muscle Vibration on Mechanical Power Output and Neuromuscular Activity During Counterbalanced RPE-clamped Cycling: A Randomized Controlled Trial
The purpose of this study is to find out if applying mild mechanical vibration (100 Hz) to the the Achilles and patellar tendons before and during exercise can make cycling feel easier and help athletes generate more power.
- Conditions
- Muscle Fatigue, Exertion, Perceived, Neuromuscular Activity, Athletic Performance
- Trial name
- NCT07715292
- Testing
- Tendo device Vibrration, Laboratory control vibration
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wrocław University of Science and Technology
Athletic Performance, Hyperbaric Oxygenation
Acute Effects of Post-Exercise Hyperoxia on Recovery in Cycling
This study examines whether exposition to hyperbaric oxygen after a road-race simulation can help competitive cyclists recover and perform better the following day.
- Conditions
- Athletic Performance, Hyperbaric Oxygenation, Physical Endurance, Muscle Fatigue
- Trial name
- NCT07659301
- Testing
- Post-exercise Recovery
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Cancer Cachexia, Omega 3
Effects of Dietary Supplementation With omega3-fatty Acids (Fish Oil) and Progressive Resistance Training on Skeletal Muscle Status in Gynaecological, Gastrointestinal and Urological Cancer Patients
Cancer cachexia is a common and prognostically relevant complication of advanced malignancies, characterized by systemic inflammation, increased catabolism, and reduced nutritional intake, leading to a progressive loss of…
- Conditions
- Cancer Cachexia, Omega 3, Resistance Training, Cancer
- Trial name
- SUPPORT (NCT07643558)
- Testing
- Omega 3 FA (Fish Oil), Training
- Where
- Germany
- Volunteers
- 288 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Cancer, Fatigue
The Effect of Progressive Muscle Relaxation and Deep Breathing Exercises Applied to Palliative Care Cancer Patients on Dyspnea, Fatigue, and Self-Care Behaviors
The purpose of this study is to evaluate the effects of Progressive Muscle Relaxation (PMR) exercises and deep breathing exercises on dyspnea, fatigue, and self-care behaviors among cancer patients receiving palliative care.
- Conditions
- Cancer, Fatigue, Palliative Care, Progressive Muscle Relaxation
- Trial name
- NCT07619209
- Testing
- Progressive Muscle Relaxation, Deep Breathing Exercises
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara University