Clinical trials: Muscle Function
Peripheral Arterial Disease
Functional MRI of the Lower Extremities
In this project, the investigators propose to use high-resolution magnetic resonance imaging (MRI) to measure blood perfusion in different groups of calf muscle.
- Trial name
- NCT03423316
- Testing
- Supervised exercise therapy
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Age-Related Sarcopenia
High-Intensity Interval Training for Older Adults
This study will examine differences in a 12 week high-intensity interval training regimen. The Total Body HIIT program incorporates a resistance (circuit) and an anaerobic (bike) component in older adults.
- Trial name
- NCT05542758
- Testing
- Total Body HIIT Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Creighton University
Health Behavior
Cold Water Immersion in the Recovery of Markers of Muscle Damage of 10km Street Runners
Objective: To analyze the effect of cold water immersion (CWI) on the recovery of clinical, biochemical, functional and neuromuscular markers of muscle damage in 10 km street runners.
- Trial name
- NCT03094689
- Testing
- Cold water immersion, Water immersion
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Spinal Muscular Atrophy Type 3, Duchenne Muscular Dystrophy
Wearable Technology to Assess Gait Function in SMA and DMD
The purpose of this project is to devise instrumented insoles capable of accurately measuring gait at each footfall, over multiple hours in any environment.
- Trial name
- NCT04193085
- Testing
- Observational
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Columbia University
Aging, Older Adults
Effects of Resistance Training in Untrained Older Adults
The latest randomized controlled trials and systematic reviews of resistance training performed by older adults reported that the systematic use of exercise in machines improves muscle strength and power, functional abilities…
- Trial name
- NCT02253615
- Testing
- Machines exercises, Elastic exercises
- Where
- Brazil
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Sarcopenia
Creatine HCl Supplementation in Sarcopenia: A Randomized Controlled Study
The CONCRET-SARCOPA trial is a 12-week, double-blind, randomized controlled study designed to evaluate the efficacy of creatine HCl supplementation in older adults with sarcopenia.
- Trial name
- SARCOPA (NCT07285226)
- Testing
- Experimental 1, Experimental 2
- Where
- Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Obese, Muscle Strength
Functional Impact of Interval Training on Muscle Mass and Strength in Obese Adults
The primary objective was to investigate the effectiveness of interval training and to evaluate the best available method for measuring body composition and functional capacity.
- Conditions
- Obese, Muscle Strength, Interval Training
- Trial name
- NCT04693117
- Testing
- Interval Training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Antenatal Care Model, Gestatiaonl Diabetes Mellitus
Effects Of Core Canister Training in Pregnant Women With History of Gestational Diabetes Mellitus
This randomized control trial aims to determine the effects of structured Core Canister Training on muscular thickness, lumbopelvic stability and pelvic floor function in pregnant women diagnosed with GDM
- Trial name
- NCT07889791
- Testing
- core canister training, traditional antenatal exercises
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Healthy Volunteers, Neuromuscular Function
Eco-guided Neuromodulation of the Femoral Nerve on the Performance of Amateur Athletes.
This randomized crossover study aims to evaluate whether different percutaneous electrical nerve stimulation (PENS) protocols produce changes in neuromuscular performance in healthy adults.
- Trial name
- NCT07719179
- Testing
- Theta Burst Protocol, 10-10-10 Protocol, 5-55 Protocol
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Muscular Weakness, Sexual Behavior
Supplement Study: Strength, Testosterone, Sexual Function, Quality of Life
Decreased muscle mass (sarcopenia) and strength (dynapenia) are common during aging, with a rate of muscle mass loss that is approximately 6% per decade between 30 and 70 years of age.
- Conditions
- Muscular Weakness, Sexual Behavior, Quality of Life
- Trial name
- NCT03457740
- Testing
- Formula 1, Formula 2
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Roam Rolling, Muscle Recovery
Effects of Foam Rolling on Plantar Flexor Recovery in Healthy Individuals
Foam rolling (FR) is a self-myofascial release technique that involves using body weight to apply pressure to soft tissues through a foam roller.
- Trial name
- NCT07759388
- Testing
- Foam rolling
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Muscle, Cognitive Functioning
This Study Investigates β-hydroxy-β-methylbutyrate (HMB) and 2-hydroxybenzylamine (2-HOBA), When Administered Either Individually or in Combination Contributes to an Increased Quality of Health, Specifically Improving Muscular Strength and Cognitive Functioning in Adults Over the Age of 65.
In this study, participants will be assigned to receive HMB, 2-HOBA, a combination of both, or a comparison supplement for a set period of time.
- Conditions
- Muscle, Cognitive Functioning, Geriatric, Ageing and Geriatric Health
- Trial name
- H2AGE (NCT07419633)
- Testing
- β-Hydroxy-β-methylbutyrate, 2-hydroxybenzylamine, β-Hydroxy-β-methylbutyrate and 2-hydroxybenzylamine
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cognition Disorders in Old Age, Cognitive Function
Impact of Nutrition, Sleep, and Physical Activity on Intellectual Function and Muscle Mass in Older Adults
The goal of this prospective, single site, interventional randomized control trial is to treat age related health conditions in adults older than 65 years and functional independence.
- Conditions
- Cognition Disorders in Old Age, Cognitive Function, Frailty/Sarcopenia, MCI
- Trial name
- INSPIOR (NCT06135740)
- Testing
- Fitbit wearing, with notification for sleep, activity and nutrition based fitbit data, Routine care
- Where
- Japan
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Tokyo University
Seniors, Old Age
Mental Effort During Low Load Resistance Training in Older Adults
The goal of this clinical trial is to determine the effect of maximal mental effort combined with low-intensity resistance training on strength and neuromuscular function in older adults.
- Conditions
- Seniors, Old Age, Sarcopenia
- Trial name
- NCT07687316
- Testing
- Low Intensity Resistance Training with Maximal Mental Effort, Low Intensity Resistance Training
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Prediabetes, Obese
Inflammation Inhibition in Prediabetic Humans
Prediabetes, characterized by elevated fasting blood sugar or exaggerated blood sugar response to sugar ingestion, effects over 79 million adult Americans and is a precursor to the development of Type 2 diabetes.
- Trial name
- INCITE (NCT01977417)
- Testing
- Salsalate
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Gary L. Pierce
Dynapenia
Blood Flow Restriction Parameters and Lower Limb Function in Older Adults With Dynapenia
The objective of the first year is to collect limb occlusion pressure (LOP) measurements in older adults with varying levels of muscle health, which will serve as foundational data for subsequent investigations on blood flow…
- Trial name
- NCT07534150
- Testing
- Blood Flow Restriction, Conventional Resistance Training
- Where
- Taiwan
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Healthy Aging, Physical Fitness
Effects of Core Stability Training Using Pilates on Core Muscle Strength, Pulmonary Function, and Cardio-respiratory Fitness in the Elderly.
This study investigates how different types of exercise-specifically Mat Pilates and Aerobic training-can help improve the physical health and breathing capacity of healthy older adults aged 60 to 77.
- Conditions
- Healthy Aging, Physical Fitness, Core Stability, Respiratory Function
- Trial name
- PLT-AER-ELD (NCT07470060)
- Testing
- Mat Pilates Program, Aerobic Exercise (Treadmill Walking)
- Where
- Thailand
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Walailak University
Posterior Shoulder Tightness
Comparison of the Acute Effects of Different Warm-up Protocols in Overhead Athletes With Posterior Shoulder Tightness
The aim of this study is to investigate the immediate effects of different warm-up protocols on Shoulder mobility, Muscle stiffness, Muscle power performance, Shoulder functional ability and Shoulder endurance in overhead…
- Trial name
- NCT06928103
- Testing
- Dynamic stretching, Static stretching and dynamic stretching, Dynamic stretching and foam rolling
- Where
- 2 sites in Taiwan
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Physical Function in Older Adults, Body Composition
Four-Week Multicomponent Exercise Program in Older Adults
This study evaluated the effects of a four-week supervised multicomponent exercise program on physical function and body composition in older adults.
- Trial name
- NCT07854860
- Testing
- Multicomponent Exercise Program
- Where
- Poland
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Gulf War Illness, Persian Gulf War Syndrome
Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
Determine if: genetic differences of CNDP1 gene the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents psychometric other variables can differentiate between veterans of the 1990-1991…
- Trial name
- NCT00810225
- Where
- United States
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- Georgetown University