Clinical trials: Muscle Function
25-hydroxyvitamin D Concentration (Vitamin D Status)
D-Light Intervention
Vitamin D insufficiency has become a global concern, with low vitamin D status associated with bone disorders, cardiovascular disease and certain cancers.
- Trial name
- D-Light (NCT02495584)
- Testing
- Fortified milk (10µg vitamin D3), 10µg vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Piriformis Syndrome, Musculoskeletal Abnormalities
Comparing Two Soft Tissues Technique on Piriformis Syndrome Patients
Piriformis Syndrome is a neuromuscular condition with symptoms of pain, numbness and tingling tracing the route of the sciatic nerve, due to the nerve impingement by the piriformis muscle.
- Conditions
- Piriformis Syndrome, Musculoskeletal Abnormalities, Sciatica
- Trial name
- MPR-PIR (NCT07661485)
- Testing
- Myofascial Release, Post Isometric Relaxation
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- University of Faisalabad
Osteo Arthritis Knee
Effects of Closed and Open Kinetic Chain Exercises
Osteoarthritis (OA) is a heterogeneous pathology characterized by focal cartilage degeneration and the formation of new bone around the subchondral bone and joint, which is the disruption of balance between the processes of…
- Trial name
- NCT04186143
- Testing
- Closed Cinetic Chain Exercises, Open Kinetic Chain Exercises, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University
Sarcopenia
The Foods & Oil to Repair, Correct and Enhance Strength (FORCES) Study
The proposed research is a parallel arm, randomized placebo-controlled clinical trial designed to assess changes in muscle strength, volume, fatigue resistance, and mobility in older adults after daily consumption of 12g of…
- Trial name
- NCT06361511
- Testing
- High Linoleic Acid Foods, High Oleic Acid Foods
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ohio State University
Stroke, Hemiparesis
CONSTRAINT-INDUCED MOVEMENT THERAPY (CIMT) VS. MIRROR THERAPY (MT) ON HAND FUNCTION AND SPASTICITY IN PATIENTS WITH HEMIPARESIS
This study aimed to compare the effects of Constraint-Induced Movement Therapy (CIMT) and Mirror Therapy (MT) on hand function and spasticity in individuals with hemiparesis.
- Conditions
- Stroke, Hemiparesis, Hemiparesis After Stroke
- Trial name
- NCT06910904
- Testing
- Constraint-Induced Movement Therapy (CIMT), Mirror Therapy (MT)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- University of Lahore
Heart Failure, Aerobic Exercise
Effects of Rehabilitation in Patients With Stable Chronic Heart Failure
Heart failure (HF) is a major public health problem. This is the first cause of hospitalization and mortality of about 65 years old. This syndrome is characterized by a poor prognosis and a high cost of care.
- Conditions
- Heart Failure, Aerobic Exercise, Quality of Life, Respiratory Muscle Training
- Trial name
- NCT03538249
- Testing
- Aerobic training, Inspiratory muscle training, Resistance Training
- Volunteers
- 60 people
- Sponsor
- Lebanese University
Shoulder Impingement Syndrome
Effects of Eccentric Training for Shoulder Abductors in Subjects With Shoulder Impingement Syndrome
The aim of the study was to evaluate the effect of eccentric strength training for shoulder abductors on force steadiness in subjects with subacromial impingement syndrome (SIS).
- Trial name
- NCT01090271
- Testing
- Isokinetic eccentric training
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Universidade Federal de Sao Carlos
Hamstring Injury, Muscle Tone Increased
Cranial Laser Reflex Technique for Hamstring Function
Purpose: To conduct a pilot study of the effect of Cranial Laser Reflex Technique (CLRT) compared with sham laser on hamstring muscle flexibility, strength, and pain pressure threshold.
- Conditions
- Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
- Trial name
- CLRTHam (NCT03044106)
- Testing
- CLRT
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Parkinson Disease
Effects of Walking and Respiratory Muscle Training on Pulmonary Function and Functional Exercise Capacity in PD
The purpose of this randomised and controlled study is to investigate the effects of walking training combined with respiratory muscle training on pulmonary function, respiratory muscle strength, and functional exercise capacity.
- Trial name
- NCT04834258
- Testing
- Walking and respiratory training, Respiratory muscle training
- Volunteers
- 30 people
- Sponsor
- Marmara University
Adolescent Idiopathic Scoliosis (AIS), Scoliosis; Adolescence
Effects of Expiratory Muscle Strength Training in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis result in deterioration of core muscles and respiratory system. Core muscles provide trunk stabilization as well as responsible for respiratory system. Especially tr.
- Trial name
- NCT06752993
- Testing
- Expiratory Muscle Strength Training (EMST-150)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Gazi University
Hernias, Diaphragmatic, Congenital
Resistance Exercise in Children With Post-operative Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a life-threatening condition with long-term complications including respiratory tract infections, respiratory muscle weakness, and abnormal lung functions.
- Trial name
- hernia (NCT04900649)
- Testing
- chest resistance exercise, chest expansion exercises
- Where
- Saudi Arabia
- Volunteers
- 32 people
- Sponsor
- Qassim University
Healthy, Obesity
Mitochondrial Function in Circulating Cells and Muscle Tissue
The main goal of this project is to determine whether mitochondrial function in circulating cells is related to that measured in the muscle fibers of the same subjects.
- Conditions
- Healthy, Obesity, Insulin Sensitivity, Women
- Trial name
- MitoWomen (NCT02700698)
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy
Impact of an Orthotic Intervention in Children With Peripheral Neuropathy
This research study will investigate the effect of two orthotic (brace) devices for the ankle and foot on walking and ankle flexibility in children with cancer not involving the brain or spinal cord.
- Conditions
- Gait, Drop Foot, Chemotherapy-induced Peripheral Neuropathy, Acute Lymphocytic Leukemia, Pediatric, Rhabdomyosarcoma
- Trial name
- IOPN (NCT03655587)
- Testing
- Solid ankle foot orthotic, Resting night splint
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Functional Independence, Respiratory Insufficiency
More Air - Better Performance - Faster Recovery
The objective of this study is to investigate i) the effect of 3 weeks IMT to adults post-stroke to maximal inspiratory pressure (MIP) and ii) the effects of 3 weeks IMT to the degree of dependency in activities of daily living…
- Trial name
- IMT (NCT04686019)
- Testing
- Inspiratory muscle training (IMT)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Central Jutland Regional Hospital
Stroke
Neural Mobilization for Reduction of Spasticity in Stroke
Spasticity after stroke is common that affect upper limb strength and make activities of daily living difficult. There are many techniques but not any standardized technique for long term effect on reduction of spasticity and…
- Trial name
- NCT05314465
- Testing
- Median nerve mobilization
- Where
- 3 sites in India
- Volunteers
- 7 people
- Sponsor
- Asir John Samuel
Obesity, Diabetes, Nutrition, Physical Health, Body Composition Changes
The Role of Nutrition in Muscle Function of Bariatric Surgery Patients
Current recommendations for protein intake after bariatric surgery are not based on strong scientific evidence. It remains unclear how much protein should be eaten to minimize muscle loss and preserve the metabolism and function…
- Conditions
- Obesity, Diabetes, Nutrition, Physical Health, Body Composition Changes, Muscle Function, Handgrip Strength Test, Protein Metabolism
- Trial name
- NCT06680492
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Bronchiectasis
Physical Capacity in Patients With Bronchiectasis Before and After Rehabilitation Program
The hypothesis of this study is that the group of patients who will carry out the rehabilitation program associated with respiratory therapy will have higher benefits in physical function, peripheral muscle strength and quality…
- Trial name
- PCBCQ (NCT02208830)
- Testing
- pulmonary rehabilitation, conventional program
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Nove de Julho
Exercise Training
Football 4 Health in Middle-aged to Older Adults
Ageing in humans is accompanied by a progressive decline in lower-limb muscle power production. In addition to a decline in musculoskeletal fitness, ageing is associated with a reduction in cardiovascular and metabolic fitness.
- Trial name
- NCT05722899
- Testing
- Football training
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Fibromyalgia Syndrome
Unilateral and Bilateral taVNS in Fibromyalgia
This randomized controlled trial aimed to compare the effects of unilateral (left-sided) and bilateral transcutaneous auricular vagus nerve stimulation (taVNS) combined with a home exercise program on clinical outcomes, autonomic…
- Trial name
- taVNS-FMS (NCT07577102)
- Testing
- taVNS, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Gelisim University
Spinal Cord Injury
Effect of Blood Flow-restricted Exercise Frequency on Strength Recovery Following Incomplete SCI
The goal of this clinical trial is to determine the effect of treatment frequency on the physical recovery of adults with incomplete spinal cord injury.
- Trial name
- NCT07678437
- Testing
- Blood flow-restricted exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Quality Living, Inc.