Clinical trials: Muscle Hypertrophy
Heart Failure, Heart Dilation
The Use of Blood Biochemical Markers for Diagnostics of Heart Muscle Diseases
The aim of the study is to determine the analytical characteristics of the microRNA enzymatic immunoassay (miREIA) method and to determine various relations among miRNA biomarkers and heart failure (HF) with reduced ejection…
- Conditions
- Heart Failure, Heart Dilation, Left Ventricular Hypertrophy
- Trial name
- NCT05726695
- Testing
- microRNA test, Heart ultrasound examination
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Ostrava
Strength Training, Dietary Proteins
Comparison of the Increment of Neuromuscular Parameters in Vegetarians and Non-vegetarians
A strength training session promotes increased muscle sensitivity to protein synthesis, which lasts for 24 hours after its closure.
- Conditions
- Strength Training, Dietary Proteins, Muscle Strength, Hypertrophy
- Trial name
- NCT03785002
- Testing
- Strength training, Protein intake
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Skeletal Muscle Hypertrophy
Effects of a Multi-ingredient Supplement Study: a Randomized Controlled Trial in Men and Women
Resistance exercise training is a known stimulant for muscle protein synthesis (MPS) to occur, however the consumption of protein is also necessary to induce a shift towards a positive net protein balance.
- Trial name
- SRCT (NCT03525197)
- Testing
- Whey protein-based supplement, Collagen protein-based supplement
- Where
- 2 sites in Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- McMaster University
Spinal Cord Injuries
Novel Intervention to Influence Muscle Plasticity in Veterans
The loss of muscle contraction (paralysis) removes an important stimulus for maintenance of overall health for individuals with complete spinal cord injury (SCI).
- Trial name
- NCT01093014
- Testing
- Low-force muscle stimulation, High-force muscle stimulation, Sequential low-force and high-force muscle stimulation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Hypertrophic Cardiomyopathy, Heart Diseases
Comparison of the Effects of Inspiratory Muscle Training and Baduanjin Exercises in Hypertrophic Cardiomyopathy Patients
The study aims to compare the effects of inspiratory muscle training and Baduanjin exercises on pulmonary function, exercise capacity, and quality of life in patients with hypertrophic cardiomyopathy.
- Trial name
- NCT06490250
- Testing
- Inspiratory Muscle Training, Baduanjin Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul University - Cerrahpasa
Resistance Exercise, Muscle Hypertrophy
Muscle Adaptations in Children and Adults Following Twelve Weeks of Flywheel or Weight Stack Resistance Exercise
The goal of this trial is to compare resistance exercise using traditional techniques and flywheel training to controls in healthy children ages nine to 13 and adults ages 18 to 50.
- Conditions
- Resistance Exercise, Muscle Hypertrophy, Skeletal Muscle, EMG
- Trial name
- KidREx (NCT06698055)
- Testing
- Flywheel Resistance Exercise, Weight Stack Resistance Exercise
- Where
- Sweden
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Björn Alkner
Hypertrophy, Exercise Training
Resistance Training, Detraining, and Retraining Study 2024 (TraDeRe2024)
The goals of our research project are to identify factors explaining inter-individual variation in responses to resistance training (RT) and the baseline determinants underlying an individual's sensitivity to respond to RT.
- Conditions
- Hypertrophy, Exercise Training, Skeletal Muscle Atrophy, Healthy
- Trial name
- TraDeRe (NCT06573086)
- Testing
- Resistance Training
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Obesity, Overweight
Low Carbohydrate and Conventional Diets Associated to Resistance Training on Muscle Fitness and Health Markers
The purpose of this study was to compare the effects of two different diets (low carbohydrate - LCD and conventional - CONV) on body composition, strength performance, muscle mass and biomarkers of health in overweight adults…
- Trial name
- LCD-RT (NCT01096836)
- Testing
- macronutrient and energy manipulation
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Gama Filho
Resistance Training
The Effects of Leucine Metabolites in Performance, Body Composition and Biochemical Markers of Muscle Damage
This study aimed to conduct a double-blind randomized pragmatic trial to evaluate the effects of off-the-shelf leucine metabolite supplements HMB-FA, HMB-Ca, alfa-HICA, on resistance training-induced changes in body composition…
- Trial name
- LMET2IMPROVE (NCT03511092)
- Testing
- HMB-FA, HMB-Ca, alfa-HICA
- Where
- Portugal
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Healthy Nutrition
Effect of Ketogenic Diet on Muscle Hypertrophy
The purpose of this study is to investigate the effects of 4 weeks of carbohydrate deprivation (through a ketogenic diet) on hypertrophy signalling after a single bout of exercise in healthy trained male subjects, and the impact…
- Trial name
- NCT05897567
- Testing
- resistance training, ketogenic diet, western diet
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Padova
Skeletal Muscle Hypertrophy, Muscle Weakness
The Effects of Lifting Light or Heavy Weights on Muscle Growth and Strength in Trained Young Men
When practicing weightlifting regularly the body makes new proteins within the muscle. These new proteins can increase the size of the cells within the muscle to make them larger, a process called hypertrophy.
- Trial name
- NCT02139865
- Testing
- 30% 1RM, 80% 1RM
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Muscle Strength, Hypertrophy
Effect of Cross-Education in Blood Flow Restriction Resistance Training on Lower Limbs in Older Women
Unilateral resistance training has been shown to promote strength adaptations in the directly trained limb and also improve strength in the contralateral limb, a phenomenon known as cross-education (CE), with more pronounced…
- Trial name
- NCT07155967
- Testing
- Blood Flow Restriction Cuff
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Paulista University
Hypertrophy
Egg Consumption and Muscular Adaptations
Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality.
- Trial name
- NCT04381390
- Testing
- Whole egg and resistance training, Egg whites and resistance training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexei Wong
Muscle Hypertrophy, Muscle Strength
Hip Thrust Versus Back Squat Training in Untrained Adults
This study compared the effects of two lower-body resistance training exercises - the barbell back squat and the barbell hip thrust - on muscle growth and strength in untrained young adults.
- Trial name
- HTS (NCT07760220)
- Testing
- Resistance training
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Auburn University
Hypertension
Genetic Analysis of African-Americans With High Blood Pressure
The purpose of this study is to learn if kinase, a protein found in the heart, contributes to thickening of the heart muscle in people with high blood pressure. A protein called myosin causes the heart to contract and relax.
- Trial name
- NCT00353925
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertrophy, Muscle Strength
Effect of Low-load Resistance Training vs. High-intensity Interval Training on Local Muscle Endurance
Local muscle endurance (LME) is the ability of a muscle(s) to resist fatigue and is needed for daily activities of life such as climbing stairs, lifting/moving objects, and in sport contexts like rock climbing, mixed martial…
- Conditions
- Hypertrophy, Muscle Strength, High-Intensity Interval Training, Resistance Training
- Trial name
- LLSIT (NCT05945641)
- Testing
- Low Load Resistance training, Sprint/High Intensity Interval Training
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Smartphone Addiction, Masseter Muscle Hypertrophy
Investigating the Effects of Smartphone Use on the Masseter Muscle
The aim of this study was to determine the short- and long-term effects of smartphone use on the masseter muscle. In the short term, to investigate whether repetitive thumb movements during phone use will cause a spontaneous…
- Conditions
- Smartphone Addiction, Masseter Muscle Hypertrophy, Masseter Muscle Spasm
- Trial name
- NCT06408766
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Physical Activity
The Impact of Exercise With Blood Flow Restriction: Sex and Age Differences
The primary objective is to investigate whether six weeks of resistance training, in combination with blood flow restriction, produces a different adaptation in fat-free mass between males and females that are not physically…
- Trial name
- NCT05615831
- Testing
- Resistance Training with Blood flow restriction
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Healthy
Individual Response to Different Volumes of Resistance Training
The literature is not clear as to which training volume to employ during initial phases of resistance training programs to ensure optimal muscular adaptations.
- Trial name
- NCT02179307
- Testing
- 12-week progressive strength training protocol
- Where
- Norway
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Performance Enhancing Product Use
Effect of Creatine and Caffeine on Muscle Performance
To determine if creatine and caffeine can be co-supplemented without inhibiting the effects of creatine.
- Trial name
- NCT04290819
- Testing
- Creatine Monohydrate, Creatine Monohydrate and Caffeine, Caffeine
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Regina