Clinical trials: Muscle Hypotrophy
Sarcopenia
Characterization of the Nutritional Status in the Patient With Liver Cirrhosis
In the subgroup of patients with sarcopenia, regardless of their body mass index, we want to verify the real impact of nutritional supplements with branched chain amino acids on the standard treatment based on nutritional…
- Trial name
- NCT04073693
- Testing
- Branched chain amino acids (BRCA)
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Puerta de Hierro University Hospital
Muscle Atrophy in Lung Cancer and Hemodialysed Patients
Muscle Wasting in Hemodialysis Patient
Muscle wasting is present in almost 50% of patients treated with chronic hemodialysis. It is associated with an increased risk of death (particularly from cardiovascular causes) and compromises quality of life (loss of autonomy…
- Trial name
- NCT03583177
- Testing
- No intervention
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Gastric Cancers, Colorectal Cancer
Predictive Effect of Abdominal Fat and Muscle Area Calculated Based on Abdominal CT on Gastric Cancer Patients
This study aims to create a clinical prediction model. Abdominal fat and muscle area also play an important role in the prediction of surgical outcomes in colorectal cancer.
- Conditions
- Gastric Cancers, Colorectal Cancer, Sarcopenia, Obesity and Overweight
- Trial name
- NCT06606912
- Testing
- Skeletal muscle, subcutaneous fat and visceral fat area
- Where
- 3 sites in China
- Volunteers
- 4,000 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Sarcopenia
Lower-Limb Rehabilitation Robot Training for Sarcopenia
The goal of this clinical trial is to learn whether lower-limb rehabilitation robot training combined with nutrition education can improve muscle mass and physical function in adults aged 60 years or older with sarcopenia.
- Trial name
- NCT07830472
- Testing
- Lower-Limb Rehabilitation Robot Training, Nutrition Education, Usual Care Exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University Hospital
Upper Gastrointestinal Disorders, Lower Gastrointestinal Disorders
Sarcopenia and Physiology Assessments in Cancer Patients
Primary Aim: To establish a reliable relationship between oxygen uptake (VO2) at estimated lactate threshold (AT) and CT-derived body composition measurments (e.g.
- Conditions
- Upper Gastrointestinal Disorders, Lower Gastrointestinal Disorders, Hepatobiliary Cancer
- Trial name
- NCT03641118
- Testing
- Cardiopulmonary exercise test
- Where
- United Kingdom
- Volunteers
- 639 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Sarcopenia
Effects of Multicomponent Training in Older Adults
The purpose of the study was to determine whether community-dwelling older adults would experience improved patient-reported outcomes and physical performance after completing an 8-week multicomponent exercise training program…
- Trial name
- NCT06094413
- Testing
- Multicomponent Training Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Geisinger Clinic
Handgrip Strength Test, Sarcopenia
Feasibility of Systematic Handgrip Strength (HGS) Testing and Short-term Changes in Muscle Strength in Digestive Cancer Patients Treated by Chemotherapy
Sarcopenia is defined as a loss in skeletal muscle mass and function (strength and/or performance). There is a high prevalence in elderly and in patients with cancer.
- Conditions
- Handgrip Strength Test, Sarcopenia, Digestive Cancer, Muscle Strength
- Trial name
- FIGHTDIGO (NCT02797197)
- Testing
- handgrip strength test, chemotherapy
- Volunteers
- 201 people
- Sponsor
- CHU de Reims
Aging, Foot Muscle Dysfunction
Effects of Rehabilitative Exergame Training on Foot Muscle Activity, Balance, and Mobility in Older Adults
This study is designed as a randomized controlled trial. A total of 40 healthy older adults residing in private and public nursing homes and rehabilitation centers in Mersin will be enrolled.
- Conditions
- Aging, Foot Muscle Dysfunction, Sarcopenia, Age-Related Muscle Weakness
- Trial name
- EXG-FOOT (NCT07357662)
- Testing
- Exergame-based Balance and Foot Muscle Training, Conventional Functional Balance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tarsus University
Advanced Lung Disease, Lung Transplant
Progressive Rehabilitation Therapy in Patients With Advanced Lung Disease
The International Society of Heart and Lung Transplantation Registry data shows that there is a growing population of critically ill patients with advanced lung disease undergoing lung transplantation.
- Conditions
- Advanced Lung Disease, Lung Transplant, Extracorporeal Membrane Oxygenation
- Trial name
- NCT03562728
- Testing
- MRP and NMES(neuromuscular electric stimulation), Standard of Care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Maryland, Baltimore
Sarcopenia
Outcome of Exercise With a Towel in Elderly With Sarcopenia
As the proportion of older adults increases, elderly-related issues attract more attention. Sarcopenia is one of the popular elderly-related issues.
- Trial name
- NCT03258827
- Testing
- Exercise with a towel, Home-based exercise
- Where
- Taiwan
- Volunteers
- 53 people
- Sponsor
- Chang Gung Memorial Hospital
Muscle Weakness
Muscle Wasting in the Critically Ill
Muscle wasting is a common consequence of critical illness, and has a profound impact upon the rehabilitation of those who survive admission to critical to care.
- Trial name
- NCT03770442
- Testing
- Cycling with FES, Routine physiotherapy
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Liverpool
Sarcopenia, Syndrome; Institutionalization
Preventive Physiotherapy Intervention in Elderly People With Sarcopenia
This study evaluates two strength training protocols (one in peripheral muscles and one in inspiratory muscles) in the improvement of skeletal muscle mass and function in institutionalized elderly with sarcopenia.
- Trial name
- NCT02120586
- Testing
- Inspiratory Muscle Training (IMT)., Peripheral muscle training
- Where
- Spain
- Volunteers
- 91 people
- Sponsor
- University of Valencia
Spinal Muscular Atrophy
Improving Standards of Care and Translational Research in Spinal Muscular Atrophy (SMA)
The SMA REACH UK Network is a national and international partnership between doctors and therapists involved in the care of children and adults with Spinal Muscular Atrophy. This network is supported by Biogen and SMA UK.
- Trial name
- SMA-REACH (NCT03520179)
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Frail Elderly Syndrome, Sarcopenia
TWK10 Improves Muscle Mass and Functional Performance in Frail Older Adults
To explore the effect of "Lactobacillus plantarum TWK10 (hereinafter referred to as TWK10)" produced by synbiotech Biotechnology Co., Ltd. on alleviating and improving the aging and debilitating diseases of the elderly.
- Trial name
- NCT04893746
- Testing
- Lactobacillus plantarum TWK10-L, Maltodextrin, Lactobacillus plantarum TWK10-H
- Where
- Taiwan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Amyotrophic Lateral Sclerosis, Progressive Muscular Atrophy
Study of ALS Reversals 2: Genetic Analyses
The purpose of this study is to try to understand why reversals of amyotrophic lateral sclerosis (ALS) and primary muscular atrophy (PMA) take place.
- Trial name
- StAR2 (NCT03464903)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Duke University
Sarcopenia, Collagen Degeneration
Effects of Whey Protein Supplementation Collagen Associated to Resistance Training in Older Woman
The main purpose of the present study was to investigate the effects of whey protein with collagen hydrolyzed following resistance training on body composition, muscular strength, functional capacity, and plasma-metabolism…
- Trial name
- NCT04621383
- Testing
- Whey protein plus collagen, Whey protein plus maltodextrin
- Where
- Brazil
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Bone Diseases, Metabolic, Acid-Base Imbalance
Short Term Bed Rest Study: Evaluation of the Use of Artificial Gravity, Induced by Short-arm Centrifugation
Randomized cross-over design with 10 male subjects and 3 campaigns to test whether the negative effects of bed rest (6º head-down tilt) on the various systems of the body and the consequences to health of simulated weightlessness…
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- SAG (NCT01820702)
- Testing
- Defined Training Programme
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Breast Cancer Survivorship, Sarcopenia
Nutrition, Exercise, and Breast Cancer Survivorship
The purpose of the study is to examine the effects of resistance training on the reasons (mechanisms) underlying the development of fatigue, muscle weakness and wasting (sarcopenia), and impaired physical functioning (poor…
- Trial name
- NCT01151488
- Testing
- Resistance Training
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Multiple Sclerosis
Effect of Combined Exercise Training in Patients With Multiple Sclerosis
The aim of this clinical trial is exercise in sarcopenic MS patients to demonstrate the effectiveness of education. The main questions it aims to answer are: -Can exercise training make a change in muscle thickness in sarcopenic…
- Trial name
- NCT06595394
- Testing
- Exercise, Home program
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Uskudar University
Sarcopenia
Amino Acid Bioavailability in Healthy Elderly After Intake of an Oral Nutritional Supplement
In this study healthy older adults are requested to consume 4 different high-protein nutritional supplements. Each subject will visit the site 4 times and at every visit they will consume 1 of the 4 products after which a series…
- Trial name
- ArenA (NCT02013466)
- Testing
- Bolus ONS A, Bolus ONS B, Bolus ONS C
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nutricia Research