Clinical trials: Muscle Loss
Sarcopenia, Mitochondrial DNA
Association of Uremic Sarcopenia and Mitochondrial Copy Number and Its Clinical Correlates
Sarcopenia is the decline of muscle mass and strength with age. Evidence suggests that oxidative stress and molecular inflammation play important roles in age-related muscle atrophy.
- Trial name
- NCT03929458
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Inflammaging, Sarcopenia
Inflammaging and Muscle Protein Metabolism
The development of a low-grade, chronic, systemic inflammation observed in the elderly (inflammaing) has been associated with increased risk for skeletal muscle wasting, strength loss and functional impairments.
- Trial name
- NCT03308747
- Testing
- Instantized Whey Protein Isolate
- Where
- Greece
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Anterior Cruciate Ligament Reconstruction, Muscular Atrophy
Nutritional Intervention to Enhance Recovery After Arthroscopic Knee Surgery in Adults
Loss of skeletal muscle mass (atrophy) and strength in the lower limb are consequences of elective knee surgery as result of prolonged disuse from limb immobilization and impaired mobility, as well as pathophysiological trauma.
- Trial name
- NCT06233825
- Testing
- Omega-3 Fatty Acids and Essential Amino Acids, Safflower Oil and Non-Essential Amino Acids
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Chris McGlory, PhD
Sarcopenia, Sarcopenic Obesity
Prevalence of Sarcopenia Among Elderly Living in Care Facilities in Klang Valley, Malaysia
The primary aim of this study was to investigate the prevalence of age-related progressive decline in muscle mass and strength (Sarcopenia) among Malaysian elderly residing in long-term care facilities.
- Trial name
- NCT03903328
- Testing
- Sarcopenia assessment
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Universiti Tunku Abdul Rahman
Muscle Loss
Leucine-enriched Nutraceutical and Attenuating Muscle Loss
This leucine-enriched protein gummy (as a gummy bar/slab) will be studied to address age-related loss of muscle mass and strength/function in older persons.
- Trial name
- NCT03197402
- Testing
- Leucine-enriched protein gel delivery system, Milk protein gel delivery system
- Where
- 4 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Sarcopenia
Effects of Power-velocity Muscle Characteristics During Ageing
The purpose of this project is to investigate the age-related differences in force-velocity muscle characteristics during isolated knee extensions variable in speed and load, during cyclic movements on a usual and recumbent bike…
- Trial name
- NCT02692612
- Where
- Belgium
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Age Related Muscle Loss
Assessment of Physical Performance With A Supplementation Containing HMB in a Sample of Old Women in Good Health
The purpose of this study is to determine whether a supplementation containing β-Hydroxy-β-methylbutyrate is effective in the treatment of age-related muscle loss in a group of older women compared to a non interventional group
- Trial name
- HMB (NCT02118181)
- Testing
- HMB
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Padova
Sarcopenia
Neuromuscular Electrical Stimulation and Physical Function in Older Adults
The purpose of this placebo controlled clinical trial is to examine the effects of of neuromuscular electrical stimulation (NMES) training on physical activity, muscle function, self-efficacy, and blood markers [e.g.…
- Trial name
- NCT03509519
- Testing
- NMES-Millicurrent
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Texas State University
Muscle Hypertrophy, Bone Mineral Density Loss
Combined Whey Protein and Collagen Supplementation in Resistance-Trained Men
This study tested whether taking whey protein together with collagen peptides would provide greater benefits for muscle and bone health compared to whey protein alone, collagen alone, or a placebo.
- Conditions
- Muscle Hypertrophy, Bone Mineral Density Loss, Resistance Training Adaptation
- Trial name
- NCT07171411
- Testing
- Whey Protein + Collagen, Whey Protein, Collagen Peptides
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Sarcopenia, Dietary Exposure
The Effect of a Multi-intervention Program and Protein Food Sources on Preventing and Mitigating Sarcopenia
Sarcopenia is characterized by loss of skeletal muscle mass and strength with advancing age. It is linked to an increased risk of falls, disability, length of hospitalization, poor quality of life, and burden of health care.
- Conditions
- Sarcopenia, Dietary Exposure, Nutrition, Healthy, Bone Health
- Trial name
- NCT06173271
- Testing
- multi-intervention program and protein foods supplementation
- Where
- Taiwan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Sarcopenia, Protein Deficiency
Association of Protein Intake With Sarcopenia Among Institutionalized Elderly
This study has purpose to investigated the association of protein intake with sarcopenia in the institutionalized elderly at south tangerang
- Trial name
- NCT04685382
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Sarcopenia
Impact of Orally Administered BPM31510 on Mitochondrial Energetics in Older Adults With Sarcopenia
This study is being done to gather data on whether oral supplementation of CoQ10 is enriched in the blood and muscles in older adults with sarcopenia.
- Trial name
- COQ10 (NCT04999488)
- Testing
- BPM31510
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Colorectal Cancer, Cancer Cachexia
Structural Characteristics of Trunk and Limb Muscles in Cachectic Colorectal Cancer Patients
Until now, cancer is still associated with high morbidity and mortality, and is therefore a big issue for the public health. Colorectal cancer is the second leading cause of cancer death in developed countries.
- Trial name
- CTLm-CCP (NCT06780423)
- Testing
- Minimal invasive fine needle muscle biopsies
- Where
- 2 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Muscle Atrophy
Protein Supplementation During Luteal Phase to Stop Protein Degradation
The purpose of this research is to determine if increasing 12% of daily protein intake during the luteal phase mitigates the potential catabolic effects of progesterone on skeletal muscle.
- Trial name
- Protein (NCT07843095)
- Testing
- protein supplement
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Low Muscle Mass, Low Muscle Strength
Nutrition Ameliorates the Muscle Loss of Pre-sarcopenia in Elderly
This study evaluates the effects of a 12-week leucine-enriched protein supplementation in adults aged 60 years and more. Participants will undergo assessments of muscle mass and function, as well as metabolic profiles in blood…
- Conditions
- Low Muscle Mass, Low Muscle Strength, Low Physical Function
- Trial name
- NCT07309120
- Testing
- Participants consume two sachets daily over a 12-week intervention period.
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Health Behavior, Sarcopenia
Earlier Elderly People in Rural Areas
Social innovation in aging needs to bring new ideas and services to meet new social and welfare needs identified in recent years.
- Conditions
- Health Behavior, Sarcopenia, Nutrition, Sleep
- Trial name
- NCT05273502
- Testing
- Citizen Science intervention
- Where
- Spain
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Sarcopenia, Sarcopenia in Elderly
Determination of Skeletal Muscle Mass Index Values in the Turkish Population Using Dual Energy X-Ray Absorptiometry
Sarcopenia is defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as "a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, carrying a risk of adverse outcomes…
- Trial name
- NCT07510009
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Sarcopenia, Osteoporosis
Effect of Oral Vitamin D3 and Calcium Supplementation on Muscle and Bone Health Among Rural Post-menopausal Women
This will be three-arm parallel group trial. The goal of this intervention study is to observe the effect of vitamin D3 and calcium supplementation for the period of 6 months on improving the sarcopenia indices such as…
- Trial name
- NCT06900387
- Testing
- Tablet Calcinum-Calcium Carbonate (500mg) daily and Vitamin D3 (Cholecalciferol) tablet (60,000 IU) once a month., Tablet Tayo- Vitamin D3 (Cholecalciferol) (60,000 IU) once a month., Control Group
- Where
- India
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Dr. Anuradha Khadilkar
Myelomeningocele, Spinal Cord Injury
Reciprocating Gait Orthoses for Paraplegia Patients
Ambulation would bring many physiological and psychological benefits and getting up and walking has been a dream for paraplegia patients.The reciprocating gait orthoses (RGOs) for paraplegics particularly draws research…
- Conditions
- Myelomeningocele, Spinal Cord Injury, Spinal Muscular Atrophy
- Trial name
- UPGO (NCT02227407)
- Testing
- RGOs(reciprocating gait orthoses)
- Where
- Taiwan
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Sarcopenia
Multicomponent Training and Muscle Quality in Older Women
This study aims to evlauate the effect os a 32-week multicomponent training (MT) program on muscle architecture and muscle quality (assessed by ultrasound) in womer over 60 years.
- Trial name
- NCT07359495
- Testing
- Multicomponent training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Salamanca