Clinical trials: Muscle Loss
Aging, Sarcopenia
Impact of Fish Oil Dose on Tissue Content and Function
In this 5-month study, we will track the incorporation and washout of n-3 PUFA into different tissues following two different dosing strategies in healthy young and older volunteers. All groups will be followed for washout.
- Conditions
- Aging, Sarcopenia, Muscle Atrophy
- Trial name
- NCT04772040
- Testing
- Fish oil supplementation
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Overweight and Obesity
EXerCise wEight Loss
The overall aim of this study is to investigate the effects of home-based resistance exercise programme on changes in body composition and strength during weight loss, in people living with obesity or overweight.
- Trial name
- EXCEL (NCT05702840)
- Testing
- Resistance exercise training + weight loss group, Weight loss only group (WL)
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Osteoarthritis, Sarcopenia
To Investigate Effects of Amway Bundle Combination of Products on Osteoarthritis & Sarcopenia
The goal of this interventional study is to evaluate the effects of bundle combination of Amway All-plant protein booster with Nutrilite Lifestyle guideline and/or EMS (Electric Muscle Stimulation) device on Osteoarthritis \&…
- Trial name
- NCT05872360
- Testing
- Bundle Group 1 with Nutrilite Lifestyle, Bundle Group 2 without Nutrilite Lifestyle, Control Group 1
- Where
- 2 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Amway (China) R&D Center
Muscle Loss in Elderly
The Effects of Resistance Training and Protein Supplementation in Healthy Elderly Men and Women.
The main objective of this study is to examine the effects of resistance type exercise training combined with nutritional support on body composition and muscle characteristics in healthy elderly men and women.
- Trial name
- NCT01004588
- Testing
- Protein drink
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Muscle Loss
The Effect of Creatine on Muscle Loss
The primary aim of this study is to determine the effect of creatine supplementation on muscle mass loss during short-term immobilisation in healthy, young people.
- Trial name
- CML (NCT01894737)
- Testing
- Creatine supplementation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcopenia, Nicotinamide Adenine Dinucleotide Concentration
Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans
Frailty is an age-associated clinical condition of poor physiological reserve that increases risks for falls, hospitalization and mortality.
- Conditions
- Sarcopenia, Nicotinamide Adenine Dinucleotide Concentration, Muscle Quality and NAD+ Content
- Trial name
- NR-VET (NCT04691986)
- Testing
- Nicotinamide Riboside
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy Male Volunteers Over 65
Assessing the Impact of a Leucine Enriched Whey Protein vs Isonitrogenous Whey on Muscle Protein Synthetic Responses in the Rested and Acute Post Exercise States in Older Adults
Occupying ~45-55% of body mass, skeletal muscle is the largest organ of the body and plays a pivotal role in locomotion, structural support and whole-body metabolic health.
- Trial name
- NCT06971822
- Testing
- Protein Supplementation
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Exercise, Healthy Male/Female Subjects
Ketone Administration During Inactivity and Retraining
The aim of this study is to investigate the effect of oral ketone administration during inactivity-induced muscle atrophy and retraining-induced regeneration.
- Trial name
- NCT05398042
- Testing
- Ketone ester, Medium Chain Triglyceride (MCT) oil
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Inflammation, Immune System
Design and Development of a Functional Plant-based Beverage to Improve Nutritional Status and Immunity for the Early Elderly People to Get Well-healthy Ageing
In 2018, for the first time, the number of people aged 65 and over exceeded the number of children under the age of 5. A rise in ageing societies is coming, and new efforts are needed to ensure that this increase in life…
- Trial name
- Immugold (NCT07409480)
- Testing
- Functional plant-based beverage, Control Beverage
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Overweight, Obesity
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study
The purpose of this study is to determine whether the combination of two dietary supplements: MUSCLE 5, which contains protein, creatine and vitamin D and TRIM 7, which contains beet extract, caffeine, coenzyme Q10, alpha lipoic…
- Trial name
- NCT05384431
- Testing
- Muscle5 and TRIM7, Mixed exercise
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Exerkine Corporation
Sarcopenia, Memory Loss
Effects of Multidomain Training of Health With Aging (Train-Old)
The current study aims to determine the effect of a multidomain intervention (physical fitness, motivational and cognitive training) on body composition, sarcopenia, cardiovascular health, physical fitness, functional capacity…
- Conditions
- Sarcopenia, Memory Loss, Muscular Atrophy, Cardiovascular Diseases
- Trial name
- Train-Old (NCT05481346)
- Testing
- Multidomain training
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Obesity, Overweight With Indications for Weight Loss
Optimizing Body Composition for Function in Older Adults
The purpose of this pilot study is to compare two strategies intended to improve the health of overweight older adults by improving body composition.
- Trial name
- NCT00315146
- Testing
- Pioglitazone, Resistance exercise training to maximize muscle power, Hypocaloric diet
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Malnutrition, Sarcopenia
Sustainable Eating Pattern to Limit Malnutrition in Older Adults
The SENIOR STUDY is aimed at improving the condition of older adults and malnutrition management in and out Italian hospital settings, since malnutrition is highly prevalent, clinically relevant and potentially treatable…
- Trial name
- SENIOR (NCT05860556)
- Where
- Italy
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Sarcopenia, Pseudoexfoliation Syndrome
Pseudoexfoliation Syndrome, Sarcopenia and Chronic Pain
Aim: Pseudoexfoliation syndrome (PEX) is a systemic disease of connective tissue, it can also contribute to sarcopenia and chronic musculoskeletal pain with common pathways. 1.
- Trial name
- NCT06121154
- Testing
- SARC-F questionnaire, Gait speed, The chair rise test
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Sarcopenia
Fish Protein Supplementation and Sarcopenia Outcomes in the Community
Sarcopenia is a progressive and generalised skeletal muscle disorder involving the accelerated loss of muscle mass and function that is associated with increase adverse outcomes including falls, functional decline, frailty and…
- Trial name
- SARCO_COMM (NCT05356559)
- Testing
- Intervention, Control
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Heart Failure, Sarcopenia
The Sarcopenia Study
The goal of this cross-sectional study is to investigate the prevalence of sarcopenia in patients with Heart Failure. The main question it aims to answer is: Whether there is a difference in the prevalence of sarcopenia across…
- Conditions
- Heart Failure, Sarcopenia, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT05888688
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Bariatric Surgery, Sarcopenia
Impact of Whey Protein Supplementation on Body Weight and Metabolic Parameters of Bariatric Patients
Obesity is a metabolic disorder, characterized by an increase in the body's fat mass, which will reflect an increase in total body weight. In Brazil, overweight accounts for 53.8% of the population, and of these 18.9% are obese.
- Trial name
- NCT04510389
- Testing
- Maltodextrin, Whey
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Sarcopenia, Pediatric Cancer
Determination of Sarcopenia Risk and Related Factors in Pediatric Oncological Patients
In children, both malnutrition and sarcopenia are associated with prolongation of hospital stay, increased morbidity, mortality, and health-related complications.
- Trial name
- NCT05294380
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Trakya University
Sarcopenia
Omega-3 Fatty Acids to Combat Sarcopenia
The purpose of this study is to determine how omega-3 fatty acids influence muscle protein metabolism and mitochondrial physiology in the context of human aging.
- Trial name
- NCT02103842
- Testing
- Omega-3 fatty acids
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Accidental Falls, Loss of Muscle Strength
Interscanner Variation in Musculoskeletal Computed Tomography (CT) Measures
Maintaining strong muscles is important for the independence and quality of life in our older population. Strong muscles provide mobility and reduce the chance of falls that lead to injury.
- Trial name
- Interscanner (NCT00896415)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco