Clinical trials: Muscle Loss
Sarcopenic Obesity, Sarcopenia
Effects of Obesity on Rectus Femoris Muscle Thickness, Sarcopenia, Gait and Balance in Women
Research; It is a planned, non-invasive, controlled study in obese female volunteers and non-obese female volunteers. The population of the study consists of voluntarily non-obese women and obese women.
- Conditions
- Sarcopenic Obesity, Sarcopenia, Obesity
- Trial name
- NCT05638035
- Testing
- Ultrasonografi, Sarcopenia measurement, Zebris
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Muscle Function, Handgrip Strength Test
Muscle Assessment in Women Who Have Undergone Roux-en-Y Gastric Bypass Surgery
The purpose of this study is to assess muscle function in women at least two years after being submitted to Roux-en-Y Gastric Bypass Surgery and compare with a control group
- Trial name
- FUBA (NCT02811393)
- Testing
- Assess muscle function
- Where
- Chile
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Chile
Sarcopenia
Effect of Carnitine Supplementation and Resistance Training on Skeletal Muscle Function
The primary aim of the current research project is to explore whether nutritional supplementation and resistance training might be combined to produce synergistic effects in the prevention of muscle loss during aging.
- Trial name
- NCT03907592
- Testing
- L-carnitine supplementation, Leucine supplementation, Resistance training
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Spinal Muscular Atrophy
Aerobic Training in Patients With Spinal Muscular Atrophy Type III
Spinal muscular atrophy type III, (SMAIII) is a disease in the nerve cells in the spinal cord which leads to to progressive muscle weakness and atrophy. No effective treatment is available for SMA.
- Trial name
- NCT02003937
- Testing
- Aerobic conditioning
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cachexia, Neoplasms
Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms
Muscle mass loss is a common adverse effect of cancer. Muscle mass loss occurs with or without reduction in body weight. Cancer cachexia (CC) is the involuntary loss of body weight of >5% within 6 months and it occurs in 50-80%…
- Conditions
- Cachexia, Neoplasms, Exercise, Metabolism
- Trial name
- PANACEA (NCT05307367)
- Testing
- Exercise training
- Where
- Denmark
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Sarcopenia
NMES During the Day and Prior to Sleep
In the present study, the effect of a bolus of intrinsically labeled milk directly after one-legged NMES (Neuromuscular Electrical Stimulation) will be studied under two conditions: during the day and prior to sleep
- Trial name
- ESPRO2 (NCT02253329)
- Testing
- Dietary protein plus NMES during the day, Dietary protein plus NMES prior to sleep
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcopenia
The Influence of Daily Grapes Intake on Sarcopenia in Postmenopausal Women
Sarcopenia, characterized by loss of muscle mass and function, is a prevalent disorder in elderly individuals or individuals with chronic diseases.
- Trial name
- NCT05863507
- Testing
- Grape powder supplementation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Sarcopenia, Dysphagia
Comparison of the Swallowing Functions in Sarcopenia and Dynapenia
The purpose of the study to investigate the comparison of the swallowing functions of the sarcopenia and dynapenia in older patients
- Conditions
- Sarcopenia, Dysphagia, Swallowing Disorder
- Trial name
- NCT04960007
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Sarcopenia
Role of the Gut Microbiome on Lean Mass and Physical Function in Older Adults
The investigators recently published significant associations between circulating gut bacteria-related metabolites with lean and skeletal muscle mass and with measures of physical function in older adults, evidence that suggests…
- Trial name
- NCT02811445
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Tufts University
Sarcopenia, Aging
Sarcopenia, Obesity, and Resistance Training
The purpose of this study was to examine the effects of resistance training on sarcopenic obesity in older women.
- Conditions
- Sarcopenia, Aging, Obesity
- Trial name
- NCT02681744
- Testing
- Resistance Training
- Where
- Brazil
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Sarcopenia, Older People
Evaluation of Sarcopenia With SARC-F and Anthropometric Measurement
The aim of this study is to examine the performance of determining the sarcopenia by anthropometric measurements (mid-upper arm circumference and calf circumference) added to the SARC-F questionnaire developed as a screening tool…
- Trial name
- NCT05241886
- Testing
- anthoropometric measurement, SARC- F questionnare
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Ege University
Sarcopenia in Elderly
Muscle Strength Asymmetry In Sarkopenic And Non-sarcopenic Older Adults
The purpose of this observational study is to examine whether differences in muscle strength between the dominant and non-dominant sides of the body are associated with sarcopenia in older adults.
- Trial name
- NCT07414888
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Sarcopenic Obesity, Spinal Cord Injuries
Sarcopenic Obesity in Neurodisabilities
To describe the frequency and thresholds for sarcopenic obesity in neurodisabled persons and the fat and lean mass distribution based on various neurodisabilities
- Conditions
- Sarcopenic Obesity, Spinal Cord Injuries, Stroke, Multiple Sclerosis
- Trial name
- SarcObeNDS (NCT03863379)
- Testing
- whole body DXA
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dionyssiotis, Yannis, M.D.
Sarcopenia, Diabetes
ProMIO2.0; A Powerful Lifestyle Intervention for Older Adults From Ethnic Minorities
Older adults from ethnic minorities show on average a worse disease risk profile compared to the majority populations. An important risk factor to develop chronic diseases is the loss of muscle mass and functioning, also known as…
- Conditions
- Sarcopenia, Diabetes, Overweight, Ethnic Minorities
- Trial name
- ProMIO2 (NCT06407583)
- Testing
- ProMIO2.0 program
- Where
- Netherlands
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Amsterdam University of Applied Sciences
Sarcopenia, Handgrip Strength Test
Preoperative Performance Indicators, Preoxygenation and Oxygen Reserve Relationship
The goal of this observational study is to evaluate the relationship between preoperative cardiopulmonary performance indicators and preoxygenation efficiency along with oxygen reserve depletion in patients scheduled for elective…
- Conditions
- Sarcopenia, Handgrip Strength Test, Preoxygenation
- Trial name
- NCT07688941
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Aging, Oxidative Stress
Targeting Oxidative Stress to Prevent Vascular and Skeletal Muscle Dysfunction During Disuse
Prolonged periods of reduced activity are associated with decreased vascular function and muscle atrophy. Physical inactivity due to acute hospitalization is also associated with impaired recovery, hospital readmission, and…
- Conditions
- Aging, Oxidative Stress, Vascular Endothelium, Skeletal Muscle
- Trial name
- NCT04351113
- Testing
- MITO-AO, PB-125, Passive Leg Movement (PLM)
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Joel Trinity
Muscle Loss, Muscle Anabolism
Essential Amino Acids Supplementation and Muscle Protein Synthesis
The modern warfighter faces numerous physiological challenges including sleep deprivation, sustained intense physical activity, and caloric restriction, the combined effects of which may result in the loss of lean body mass and…
- Trial name
- NCT01366924
- Testing
- Essential Amino Acids, Endurance exercise
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Muscle Atrophy
Protein Ingestion and Skeletal Muscle Atrophy
The effect of different protein intakes on skeletal muscle atrophy during short term unilateral leg immobilisation.
- Trial name
- NCT03797781
- Testing
- Lower limb immobilisation (leg brace) with varying levels of protein intake
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Osteoarthritis, Knee, Mobility Limitation
Effects of Improved Calf Muscle Function on Gait, Balance and Joint Loading in Older Adults
This study investigates the role of calf muscle function in gait performance, balance and knee joint loading. Previous studies have linked age-related loss of calf muscle function with impairments in gait performance and balance…
- Conditions
- Osteoarthritis, Knee, Mobility Limitation, Accidental Fall
- Trial name
- NCT03921801
- Testing
- Gait retraining, Gait retraining + strength training
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland