Clinical trials: Muscle Recovery, open to volunteers
Internet-Based Cognitive Behavioral Therapy
Efficacy of Internet-Based Cognitive Behavioral Therapy for Back Muscle Strength Loss, Chronic Pain, and Poor Patient Recovery Perceptions After Lumbar Fusion
This study aims to develop an Internet-based Cognitive Behavioral Therapy protocol for core muscle training, based on an understanding of factors impeding postoperative core muscle training in lumbar surgery patients.
- Trial name
- NCT07030582
- Testing
- Internet-delivered cognitive behavioral therapy, Basic Postoperative Care, Conventional Postoperative Care
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jiawei Jiang
Insomnia, Healthy Adult
The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise-induced Muscular Pain
Sleep is a critical determinant of physiological recovery and pain regulation. Growing evidence suggests that sleep disruption directly heightens central and peripheral pain sensitivity to sensory stimuli (e.g., mechanical…
- Conditions
- Insomnia, Healthy Adult, Musculoskeletal Pain, Pain Sensitivity
- Trial name
- NCT07827664
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Type 2 Diabetes, Muscle Atrophy
The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults
The goal of this study is to determine the impact of pre-diabetes and type 2 diabetes on muscle atrophy during a period of bed rest and recovery of muscle mass, strength, and physical function following bed rest.
- Conditions
- Type 2 Diabetes, Muscle Atrophy, Aging, Sedentary Behavior
- Trial name
- REST (NCT03761446)
- Testing
- Bed rest
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Subarachnoid Hemorrhage, Muscle Atrophy
Impact of NMES and HPRO on Recovery After SAH- Pilot Study
The study purpose is to investigate the hypothesis that in adults with SAH, early neuromuscular electrical stimulation (NMES) and high protein supplementation (HPRO) will improve muscle mass, metabolic and inflammatory biomarker…
- Conditions
- Subarachnoid Hemorrhage, Muscle Atrophy, Inflammation, Nutritional and Metabolic Disease
- Trial name
- NCT03201094
- Testing
- Neuromuscular Electrical Stimulation (NMES), High Protein Supplementation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Maryland, Baltimore
Bite Force, Stainless-steel Crown
Bite Force Recovery Following Pediatric Full Crown Restorations
A component of masticatory function is bite force. Dental caries is one factor that contributes to poor dental health, which has an overall negative influence on quality of life.
- Conditions
- Bite Force, Stainless-steel Crown, Masseter Muscle
- Trial name
- NCT07786805
- Testing
- Preformed BioFlx Crown, Preformed Stainless Steel Crown
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Traumatic Spinal Cord Injury
Early Pharmacological Treatment of Acute Spasticity After Spinal Cord Injury
The objective of this clinical trial is to evaluate if early detection of spasticity and immediate treatment with oral baclofen during acute care prevents problematic spasticity and improves neurofunctional recovery after tSCI.
- Trial name
- NCT06564714
- Testing
- Early baclofen Intervention, Usual routine care
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Intensive Care Unit Syndrome, Intensive Care Neuropathy
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO).
- Conditions
- Intensive Care Unit Syndrome, Intensive Care Neuropathy, Intensive Care (ICU) Myopathy, Acute Respiratory Distress Syndrome
- Trial name
- CLEVERER (NCT03753412)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Sports Physical Therapy, Injury;Sports
Inspiratory Muscle Activation and Post-Exercise Recovery in Professional Football Players
Respiratory muscles play a fundamental role in sports performance. Fatigue of these muscles induces changes in maximal inspiratory pressure and autonomic nervous system activity, thereby compromising the athlete's recovery…
- Trial name
- NCT07373158
- Testing
- Inspiratory muscle activation via phrenic nerve modulation, Inspiratory muscle activation via threshold device
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Strength, Stress
Effects of Root Extract Ashwagandha (KSM-66) on Perception of Recovery and Muscle Strength in Adolescents Aged 11 to 19 Engaged in Grassroots Football
This study will test whether six weeks of ashwagandha (KSM-66 root extract), helps teenage footballers recover and improve strength.
- Conditions
- Strength, Stress, Exercise Adaptation, Sleep
- Trial name
- NCT07890935
- Testing
- Ashwagandha
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sports Performance and Applied Research in Trials and Analysis
Critical Illness Myopathy, Critical Illness Polyneuropathy
Improved Recovery of Walking in Acquired Muscle Weakness
The aim of Re-Walk-Easy is to evaluate the effects of rehabilitation based on electrical stimulation on the motor performance of critically ill patients.
- Trial name
- Re-Walk-Easy (NCT06786390)
- Testing
- Rehabilitation protocol: FES, Rehabilitation protocol without FES
- Where
- Italy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Healthy
Short-term Effects of Broccoli-derived Glucoraphanin on Recovery From Eccentric Muscle Damage
Eccentric exercise induces muscle damage and delay functional recovery. Broccoli-derived glucoraphanin (a sulforaphane precursor that activates Nrf2 defenses) may aid repair; however, its short-term effects in humans remains…
- Trial name
- NCT07373106
- Testing
- broccoli powder consumption
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Exercise-Induced Fatigue, Football Performance
Effects of Hydrogen-rich Water Consumption on Transient Fatigue During an Official Football Match.
The purpose of this study is to determine whether drinking hydrogen-rich water can reduce fatigue and help football players maintain high-intensity physical activity during an official football match.
- Trial name
- HRW-FOOTBALL (NCT07855120)
- Testing
- Hydrogen-Rich Water (HRW)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Palacky University
Rectal Cancer, Low Anterior Resection Syndrome
The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal Cancer
This randomized controlled trial aims to evaluate the effects of combining Kegel exercise with a single biofeedback session on bowel function, emotional distress, and quality of life in patients who have undergone low anterior…
- Conditions
- Rectal Cancer, Low Anterior Resection Syndrome, LARS - Low Anterior Resection Syndrome
- Trial name
- BFT in LARS (NCT07253298)
- Testing
- Kegel Exercise with Biofeedback, Kegel Exercise Only
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- National Taiwan University Hospital
Muscle Oxygenation, Lactate
Capacitive Resistive Electric Transfer Therapy on Muscle Recovery
This study aims to evaluate the effectiveness of Capacitive Resistive Electric Transfer (CRET) therapy combined with post-competition massage in the recovery and muscle function of professional athletes.
- Conditions
- Muscle Oxygenation, Lactate, Anaerobic Exercise
- Trial name
- NCT06906146
- Testing
- CRET therapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Performance
Chronic Grape Extract in Crosstraining Athletes: A Randomized Crossover Trial
The aim of this study is to investigate the effect of cronic GSE intake in crosstraining may have a favorable impact on biochemical markers, recovery, and performance.
- Trial name
- CROSSUVA (NCT07106281)
- Testing
- Grape Seed Extract
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Sport, Muscle Fatigue
Effect of KA-EX Supplementation on Recovery Parameters in High-Level Young Football Players
The purpose of this study is to evaluate the effects of KA-EX supplementation on recovery parameters in elite young football players.
- Conditions
- Sport, Muscle Fatigue, Recovery of Function (G11.427.698.620), Athletic Performance
- Trial name
- Effect of KA-E (NCT07824752)
- Testing
- KA-EX, Experimental: KA-EX Supplement
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Antonio Molina Lopez
Exercise-induced Myocardial Damage, Right Ventricular Diastolic Dysfunction
Effects of Exogenous Ketones on Acute Changes and Recovery of the Heart Muscle After Intense Exercise.
It is well known that scar tissue on the heart muscle can cause (life-threatening) arrhythmias. However, the exact cause of this scar tissue is not entirely clear.
- Trial name
- NCT06715748
- Testing
- Ketone Monoester (KE)
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Intensive Care Unit Acquired Weakness, Muscle Weakness
Early Assessment of Quadriceps Muscle Recovery by Dynamometry and 3D Ultrasound in Intensive Care Patients Under Invasive Mechanical Ventilation
Patients in intensive care often develop acquired muscle weakness (ICUAW or Intensive Care Unit Acquired Weakness) due to immobilization and muscle atrophy.
- Trial name
- DYNAMOREA (NCT07069959)
- Testing
- Early assessment of quadriceps muscle strength
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Muscle Atrophy or Weakness
Metformin and Muscle Recovery
A hallmark of aging is an impaired ability to adequately recover following a stressor, such as muscle disuse, resulting in muscle fibrosis and weakness thereby increasing the risk for falls and loss of independence.
- Trial name
- NCT06185179
- Testing
- Metformin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Utah
Total Knee Arthroplasty Recovery, Knee Osteoarthritis
Wearable Knee-Assisted Rehabilitation for Range of Motion and Muscle Strength After Total Knee Arthroplasty
This randomized controlled trial evaluates a wearable electrogoniometry-based telerehabilitation system designed to support recovery after total knee arthroplasty.
- Trial name
- NCT07875725
- Testing
- ReBK Wearable Telerehabilitation System, Standard Home-Based Rehabilitation
- Where
- 3 sites in Chile
- Volunteers
- 80 people
- Sponsor
- University of Chile