Clinical trials: Muscle Soreness
Muscle Injury, Muscle Soreness
Lemon Verbena Extract Oxidative Stress and Muscle Damage
In the present study, investigators investigated whether supplementation with lemon verbena extract (LVE) could improve muscle damage and biochemical indicators after exhaustive exercise challenge.
- Trial name
- NCT04742244
- Testing
- Lvemon verbena extract, maltodextrin
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Delayed Onset Muscle Soreness (DOMS)
Study to Assess the Safety, Tolerability, and Effects of CHI-202 to Support Recovery From Physical Activity
The study is designed as a proof of concept, single-center, randomized, double-blind, placebo controlled study to assess the safety and efficacy of CHI-202 (cannabinoids and other ingredients) compared to placebo in the treatment…
- Trial name
- NCT05026164
- Testing
- CHI-202, CHI-101
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Canopy Growth Corporation
Long COVID, PTLDs
A Prospective Study to Evaluate the Role of T-Cell Dysfunction in Patients Who Present Symptoms Associated With Long COVID, Lyme Disease and Myalic Encephalomyelitis / Chronic Fatigue Syndrome Using the Vira Immune Fluorospot T Cell Assay
This is a longitudinal observational study recruiting individuals that have attended three clinical sites with symptoms associated with a diagnosis of long COVID, PTLDS or ME/CFS.
- Conditions
- Long COVID, PTLDs, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3)
- Trial name
- NCT06731179
- Where
- 3 sites in United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- ViraxBio Labs
Chronic Fatigue Syndrome
Exploring Worry in CFS/ME
This study will be building on the findings of Kalfas et al 2022 paper exploring the prevalence of generalised worry in patients with Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) before and after Cognitive…
- Trial name
- NCT06011135
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- King's College London
Lower Limb Injuries
Plyometric Training on Sand vs Firm Ground in Young Adults
Summary The purpose of this interventional study is to determine whether the type of training surface used during plyometric training influences neuromuscular performance, dynamic postural balance, and muscle soreness in young…
- Trial name
- PST-SF (NCT07489404)
- Testing
- Plyometric Training on Sand
- Where
- Tunisia
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Manouba
Performance
Soft Tissue Mobilization Effects on Doms
Aim: The aim of the study was to examine and compare the time-dependent effects of IASTM and FR applications on delayed muscle pain and physical performance.
- Trial name
- NCT05328830
- Testing
- Instrument assisted soft tissue mobilization, Foam Roller
- Where
- Cyprus
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Muscle Soreness
Topical CBD's Effects on Soreness and Performance
Exercise-induced muscle damage (EIMD) results from unaccustomed exercise and can lead to delayed onset muscle soreness (DOMS). Impairments associated with EIMD and DOMS can result in moderate-to-severe discomfort and hindered…
- Trial name
- NCT06320327
- Testing
- Cannabidiol cream
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Joseph Pastina
Phototherapy
Effects of Light Emitting Diodes (LED) Therapy in Rugby Athletes
Therapy with light emitting diodes (LED) is a good resource to accelerate the recovery of the athlete and reduce muscle damage caused by exercise.
- Trial name
- NCT03728439
- Testing
- LED before, LED interval, LED after
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Physical Activity, Muscle Recovery
Effect of NMN on Muscle Recovery and Physical Capacity in Healthy Volunteers With Moderate Physical Activity
The purpose of this study is to evaluate the effect of NMN supplementation (250 and 500 mg/day over 38 days) compared to placebo in healthy volunteers with moderate physical activity on muscle recovery, physical capacity…
- Trial name
- NCT04664361
- Testing
- Nicotinamide mononucleotide
- Where
- France
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Seneque SA
Muscle Soreness
A Study to Understand the Analgesic Properties of Topically Applied Menthol When Used in a Marathon.
The purpose of the research study is to gather the opinions and/or perceptions relating to the use of topically applied menthol and experience of pain during and after a marathon in adult runners (18+ years) participating in the…
- Trial name
- NCT07565246
- Testing
- Observational
- Where
- United States
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Muscle Soreness, Perceived Recovery
Effect of Wearing a Compression Sock During Running on Muscle Soreness in Distance Runners.
Running is the most popular physical activity worldwide. Although running provides many health benefits, it is often associated with injuries and symptoms such as delayed onset muscle soreness.
- Conditions
- Muscle Soreness, Perceived Recovery, Perceived Exertion, Affective Response
- Trial name
- NCT06225388
- Testing
- Compression socks
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Electromagnetic Fields
Effect of Pulsed Electromagnetic Stimulation on DOMS
The aim of our study is to investigate the effect of Pulsed Electro Magnetic Field application on delayed muscle soreness in healthy Quadriceps femoris muscle.
- Trial name
- NCT05554874
- Testing
- Pulsed electromagnetic fields
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Soreness, Muscle, Performance Enhancing Product Use
Acute Study on Muscle Soreness, Damage, and Performance
The acute study will evaluate pre- and post-exercise ingestion of a multi-ingredient supplement in a randomized, double-blind, placebo-controlled, crossover design.
- Conditions
- Soreness, Muscle, Performance Enhancing Product Use, Damage Muscle
- Trial name
- NCT04230226
- Testing
- Pre-workout plus and protein recovery plus
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Tension-type Headache
Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache.
The aim is to investigate muscle soreness and stiffness in patients with Chronic or Frequent Episodic Tension Type Headache before and after treatment with amitriptyline - and to compare the results with healthy individuals.
- Trial name
- NCT02746250
- Testing
- Amitriptyline
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Myalgia, Muscle Pain
Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
The main aim of the presented project will be to examine the concentration of selected receptors (CB1, CB2, TRPV-1) showing affinity for binding to cannabidol (CBD) and cannabinol (CBN) in blood samples collected from people with…
- Conditions
- Myalgia, Muscle Pain, Orofacial Pain, Headache, Tension
- Trial name
- NCT06405646
- Testing
- Blood CB1, CB2, TRPV-1 concentration measurement
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Muscle Fatigue (C23.888.592.612.612), Delayed Onset Muscle Soreness (DOMS)
Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue Exercise
This randomized, parallel, placebo-controlled, double-blind clinical trial will evaluate the effects of low-intensity therapeutic ultrasound on muscle recovery after a fatiguing handgrip exercise protocol in healthy adults.
- Trial name
- NCT07871942
- Testing
- Pulsed Low-Intensity Therapeutic Ultrasound
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Muscle Soreness
Comparison of Intermittent Occlusion and Static Stretching
To determine changes in Vitals caused by Intermittent Occlusion ( 220 mg ) and to compare the effectiveness of Intermittent Occlusion and Static Stretching of the lower limb muscle group in preventing the development of exercise…
- Trial name
- NCT04574661
- Testing
- Static Stretching, Intermittent Occlusion
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Muscle Damage
Comparison of Pre-exercise Beta-hydroxy-beta-methylbutyrate Free Acid (HMB-FA) and Cold Water Therapy for the Attenuation of Muscle Damage and Soreness
Study Objectives 1. Compare beta-hydroxy-beta-methylbutyrate free acid (HMB-FA) to cold water immersion on performance recovery from an acute bout of high intensity resistance exercise. 2.
- Trial name
- NCT01793779
- Testing
- cold water immersion, beta-hydroxy-beta-methylbutyrate free acid (HMB-FA)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Delayed-onset Muscle Soreness, Sleep
Sleep and Delayed-onset Muscle Soreness
There is a need for further experimental research in order to gain a more in-depth understanding of this vicious cycle of pain and sleep disorders.
- Conditions
- Delayed-onset Muscle Soreness, Sleep, Pain
- Trial name
- NCT06699186
- Testing
- Sleep, Non-sleep
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Intubating Conditions, Fasciculations
Muscle Relaxation for Short Procedures
Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A more modern alternative is the application of low-dose rocuronium, reversed by low-dose sugammadex.
- Conditions
- Intubating Conditions, Fasciculations, Postoperative Myalgia, Patient Satisfaction
- Trial name
- NCT01902641
- Testing
- Succinylcholine, Rocuronium/Sugammadex, Rocuronium
- Where
- Germany
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH