Clinical trials: Muscle Soreness, open to volunteers
Muscle Soreness
A Study to Evaluate the Analgesic Properties of Topically Applied Menthol in Marathon Participants
The purpose of the research study is to better understand the factors that impact pain experience in adult (18+ years) marathon runners participating in the 2026 Chicago Marathon and to better understand if topically applied…
- Trial name
- NCT07873242
- Testing
- Observational, Non-Interventional Study
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Muscle Soreness
Cold Vs Warm Water Immersion for DOMS Recovery
The study investigates the effectiveness of physical strategies in addressing Delayed Onset Muscle Soreness (DOMS) in physically active individuals.
- Trial name
- NCT06804564
- Testing
- Cold Water Immersion (CWI), Hot Water Immersion (HWI), Simulated Laser Therapy
- Where
- Poland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Józef Piłsudski University of Physical Education
Estrogen Receptor-Positive Breast Carcinoma
Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase Inhibitors
This phase II trial tests how well Reishi mushroom extract works in treating fatigue and/or joint/muscle pain (arthralgias/myalgias) in patients with breast cancer on aromatase inhibitors.
- Trial name
- NCT06028022
- Testing
- Mushroom Extract, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 23 sites in United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Chronic Fatigue Syndrome (CFS)
Controlled Trial of Hydrogen Water as a Treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This is a 16-week controlled treatment trial of an over-the -counter supplement, hydrogen water, for individuals with ME/CFS patients. An active treatment condition will be compared to a placebo-control condition.
- Trial name
- ME/CFS (NCT07753122)
- Testing
- Molecular hydrogen produced by a metallic magnesium tablet, consumed 3x a day dissolved in water. Treatment duration is 16 weeks.
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Fred Friedberg
Pain, Acute
Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity
This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities.
- Trial name
- NCT06411197
- Testing
- Hypertonic saline injection, Isotonic saline injection
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kristian Kjær Petersen
Trigger Point in Trapezius Muscle
The Impact of Dry Needling on Electrophysiological and Ultrasound-based Biomarkers for Myofascial Pain
The goal of this interventional study is to determine how well dry-needling can treat pain in people with Myofascial Pain Syndrome.
- Trial name
- ENCOMPASS-2 (NCT07270276)
- Testing
- Dry Needling
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Beth Israel Deaconess Medical Center
Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle
Occlusal Equilibration vs. Sham Therapies for TMDs: Post-Trial Follow-up (OEST)
Chronic temporomandibular disorders (TMDs) affect the masticatory muscles, the temporomandibular joints (TMJs), and associated structures. Except in cases of trauma, their etiology remains uncertain, debated, and multifactorial.
- Conditions
- Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle, Arthralgia Syndrome
- Trial name
- OEST (NCT07445516)
- Where
- 2 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Urbano Santana Penin
Myofacial Pain, Pelvic Pain
Measuring Pelvic Floor Muscle Fitness Before and After Treatment
This study is being done to better understand and improve treatment for myofascial pelvic pain, a common cause of long-lasting pelvic pain in women.
- Conditions
- Myofacial Pain, Pelvic Pain, Myofascial Pelvic Pain, Chronic Pelvic Pain
- Trial name
- NCT07605598
- Testing
- Near Infrared Imaging
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Neuropathy, Diabete Mellitus
Comparison of Active vs Passive Neural Mobilizations Effects in Improving Burning Pain, Muscular Strength, and Range of Motion in Patients With Diabetic Neuropathy
Randomized controlled trial evaluating active and passive neurodynamic techniques for diabetic neuropathy. Sample size: 60 patients (30 per group), aged 40 to 65 years, diagnosed with diabetes mellitus.
- Conditions
- Neuropathy, Diabete Mellitus, Diabetic Neuropathy
- Trial name
- RCT (NCT07141992)
- Testing
- Active Neural Mobilzations, Passive Neural Mobilzations
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Fatigue Syndrome, Chronic
Assessment of Exercise Response in Chronic Fatigue Syndrome / Myalgic Encephalomyelitis.
This study evaluates the correlation between the 6-min walking test (6MWT) with gases measurement, and the peak cardiopulmonary exercise testing (CPET) using incremental cycling with gases and workload measurement, in order to…
- Trial name
- NCT03675087
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Escuela Universitaria de Fisioterapia de la Once
TMD/Orofacial Pain, Myalgia of Mastication Muscle
Botulinum Toxin in the Management of Temporo-mandibular Related Myalgia: a Prospective Study
The aim of this study was to evaluate the clinical course in terms of pain, function and quality of life of patients with TMD-related myalgia during six months after receiving BTX-A injections.
- Conditions
- TMD/Orofacial Pain, Myalgia of Mastication Muscle, Botulinum Toxin, Type a
- Trial name
- BOMAMY (NCT06677216)
- Testing
- Botulinum Toxin, Type A
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Diakonessenhuis, Utrecht
Delayed Onset Muscle Soreness Experimentally Induced
Clinical and MRI Characteristics of Delayed Onset Muscle Soreness (DOMS) of the Shoulder Rotator Muscles Induced by Eccentric Exercise: An Exploratory Prospective Experimental Study
The purpose of this study is to characterize the clinical and radiological manifestations of delayed onset muscle soreness (DOMS) experimentally induced by an isokinetic eccentric contraction protocol targeting the shoulder…
- Trial name
- DOMEX (NCT07880782)
- Testing
- Isokinetic dynamometer
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tyrosol, Creatine
The Effects of Tyrosol and Creatine on Exercise Performance and Cognition in Healthy Adults
This study will be a randomized, double-blind, placebo-controlled trial. It will be conducted over a 8-week intervention investigating the effects of creatine (5g Creatine monohydrate); placebo control (5g resistant dextrin), and…
- Conditions
- Tyrosol, Creatine, Endurance Performance, Cognition
- Trial name
- NCT07756658
- Testing
- Tyrosol, Creatine Monohydrate, Resistant Dextrin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Exercise Recovery, Physical Performance Parameters
Effects of Pork Protein on Recovery Following Simulated Fireground Activity
The goal of this clinical trial is to learn whether consuming pork-based protein before and after physically demanding simulated firefighting activities can improve recovery, physical performance, and cognitive performance in…
- Conditions
- Exercise Recovery, Physical Performance Parameters, Muscle Damage, Cognition
- Trial name
- PORK-FIRE (NCT07819565)
- Testing
- Pork-Based Protein Ready-to-Eat Meals, Plant-Based Protein Ready-to-Eat Meals, Carbohydrate-Focused Lower-Protein Ready-to-Eat Meals
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Temporomandibular Disorders
Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A
The goal of this clinical trial is to investigate the effect of botulinum toxin on neurons' plasticity in the masseter muscle in humans with and without painful myogenous temporomandibular disorders (TMDM).
- Trial name
- NCT05720065
- Testing
- Botulinum toxin type A, Isotonic saline 0,9%
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), ME/CFS Following COVID-19
Observational Study on Immunoadsorption (IA) in Patients With Autoantibody-Positive Post-Infectious ME/CFS
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a severe, often infection-triggered disease characterized by debilitating fatigue and post-exertional malaise lasting over 14 hours, along with pain, cognitive…
- Trial name
- IMPACT (NCT07529197)
- Testing
- IA with TheraSorb ® column (Miltenyi)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Charite University, Berlin, Germany
Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke
THE EFFECT OF SURGICAL MASK AND N95 MASK USE ON SURGICAL SMOKE IN OPERATING ROOM NURSES
This study was conducted to compare the effect of surgical mask and N95 mask use on physical symptoms due to surgical smoke in operating theatre nurses.
- Conditions
- Surgical Smoke Exposure, Occupational Exposure to Surgical Smoke, Headache, Dizziness
- Trial name
- NCT07404956
- Testing
- Surgical Mask, N95 Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Recovery, Psychological, Transcranial Magnetic Stimulation
Evaluating Combined Electromagnetic Stimulation for Enhanced Physical and Psychological Recovery in Athletes with DOMS
This randomized controlled trial explores the impact of a combined transcranial and peripheral electromagnetic stimulation over the potential correlation between psychological well-being and recovery outcomes of young athletes…
- Trial name
- NCT06855316
- Testing
- electromagnetic stimulation
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Myofascial Pain Syndromes, Trigger Points
Immediate Effect of Dry Needling on Calf Muscles Pain Pressure Threshold,Sprint Speed and Functional Performance in Amateur Football Player
This randomised single-blind trial will evaluate the immediate effect of a single session of dry needling versus sham needling on calf muscle myofascial trigger points among amateur football players aged 18-25 years.
- Conditions
- Myofascial Pain Syndromes, Trigger Points, Gastrocnemius Muscle
- Trial name
- NCT07525921
- Testing
- Dry Needling
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Foundation University Islamabad
Upper Extremity Muscle Pain, Upper Extremity Bone Pain
A Randomized Controlled Trial of Oral CBD for the Treatment of Upper Extremity Musculoskeletal Pain
The goal of this clinical trial is to learn about the use of cannabidiol (CBD) capsules as a treatment for musculoskeletal pain. CBD is commonly being used as an over-the-counter treatment for musculoskeletal pain.
- Conditions
- Upper Extremity Muscle Pain, Upper Extremity Bone Pain, Upper Extremity Pain
- Trial name
- NCT06695195
- Testing
- Cannabidiol (CBD)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brent DeGeorge