Clinical trials: Muscle Spasm
Attention Deficit Hyperactivity Disorder
Enhancing ADHD Driving Performance With Stimulant Medication
Among children, attention-deficit/hyperactivity disorder (ADHD) is associated with an increased risk for accidents, especially bicycle and pedestrian (Leibson 2001; Jensen 1988; DiScala 1998).
- Trial name
- NCT00572026
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Virginia
Bronchospasm, Activity/Exercise Induced Bronchospasm
A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise
During this study, your child will need to attend up to 5 office visits and maintain regular telephone contact with the clinic. Certain office visits will include physical exams, medical history review, exercise challenge test…
- Trial name
- NCT00118716
- Testing
- Fluticasone propionate/salmeterol, Fluticasone Propionate
- Where
- 50 sites in United States
- Volunteers
- 248 people
- Sponsor
- GlaxoSmithKline
Pertussis, Whooping Cough
Safety and Dose Ranging Study of Acellular Pertussis and Acellular Pertussis -Tetanus-Diphtheria Booster Vaccines in Healthy Adults Ages 18 to 40 Years
This study will evaluate the safety and efficacy of 9 different vaccines containing aP (acellular pertussis) and TdaP (acellular pertussis, tetanus and diphtheria) in healthy subjects 18 to 40 years of age.
- Conditions
- Pertussis, Whooping Cough, Tetanus, Lockjaw
- Trial name
- NCT01529645
- Testing
- Acellular pertussis vaccine, Tetanus, reduced diphtheria, and acellular pertussis vaccine (adsorbed), Licensed TdaP booster vaccine
- Where
- Belgium
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Cervical Dystonia, Blepharospasm
Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin
Our hypothesis is that botulinum toxin injections (with onabotulinum toxin, incobotulinum toxin, and abobotulinum toxin) given at 10-week or shorter intervals for the indication of treatment of muscle spasms associated with…
- Conditions
- Cervical Dystonia, Blepharospasm, Limb Dystonia, Hemifacial Spasm
- Trial name
- NCT05103202
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Texas Southwestern Medical Center
Asthma
Dose Response Study of Inhaled Ciclesonide (Glucocorticosteroid) to Patients With Persistent Asthma
To investigate the efficacy and safety of ciclesonide inhaled into the lungs in a range of doses in a new dry powder inhaler compared to ciclesonide inhaled into the lungs using a metered dose inhaler
- Trial name
- NCT00174746
- Testing
- AVE2635A
- Where
- United States
- Volunteers
- 1,145 people
- Sponsor
- Sanofi
Interstitial Cystitis, Levator Spasm
A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain
The goal of this clinical trial is to compare two different treatment patterns in patients with chronic bladder pain. The main questions the investigators are seeking to answer is if bladder pain improves before and after…
- Conditions
- Interstitial Cystitis, Levator Spasm, Bladder Pain Syndrome
- Trial name
- NCT05658874
- Testing
- Multimodal Bundle Drugs, Operative Cystoscopy, Behavioral health consultation/therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Jocelyn Fitzgerald
Trismus, Swelling
Comparison of Two Different Suture Knot Techniques on Post-Operative Trismus and Swelling After Impacted Third Molar Surgery
To compare the two different suture knot techniques, locked and unlocked, in terms of mean on postoperative trismus and swelling after impacted mandibular third molar surgery.
- Trial name
- Impacted molar (NCT07327762)
- Testing
- locking and non locking suture techniques, non locking suture technique
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Vestibular Schwannoma
Nimodipine in Vestibular Schwanommas
Title: Intraoperative application of nimodipine to the facial and cochlear nerves during vestibular schwannoma resection to avoid spasm-related postoperative facial paralysis and deafness - a prospective randomized study…
- Trial name
- NCT04801953
- Testing
- NiMODipine Injectable Solution
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Coronary Artery Spasm, Hypertension
The Prevalence of Coronary Spasm in Hypertensive Patients Treated With Antihypertensive Medication
Autonomic nerve function is involved in both blood pressure (BP) regulation and the pathogenesis of coronary artery spasm(CAS), but few studies have been published about the relationship between CAS and effect of BP lowering…
- Trial name
- NCT01882790
- Where
- 3 sites in South Korea
- Volunteers
- 1,933 people
- Sponsor
- Korea University
Postoperative Edema, Postoperative Pain
Hilotherapy vs. Kinesio Taping in Orthognathic Surgery Recovery
This prospective randomized controlled trial aims to compare the effects of kinesio taping and hilotherapy on postoperative edema, pain, and trismus in patients undergoing bimaxillary orthognathic surgery.
- Conditions
- Postoperative Edema, Postoperative Pain, Trismus, Orthognathic Surgery
- Trial name
- NCT07006610
- Testing
- Kinesio Tex® Gold Taping, Hilotherm® Facial Cooling System
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Medipol University
Cramps, Chronic Kidney Disease(CKD)
Prevalence and Severity of Cramps in Chronic Kidney Disease Patients
Cramps are a frequent and severe complication in CKD patients. Their characteristics : triggering factors, associated factors, are not well known. There is no recognized effective treatment.
- Trial name
- CRAMéREIN (NCT06737094)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vaping, Complication of Anesthesia
Perioperative Vaping Complications
Prospective observational study evaluating the incidence, and qualifying the types, of perioperative pulmonary complications in patients that vape.
- Trial name
- NCT05912023
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Navy Medical Center San Diego
Posture, Kyphosis
Effects of Telerehabilitation-based Motor Imagery and Exercise Combination in Individuals With Postural Kyphosis: A Randomized Controlled Trial
Objective: Kyphosis is one of the most common postural problems. It is defined as a thoracic curvature that exceeds normal limits.
- Conditions
- Posture, Kyphosis, Muscle Cramps, Thoracic Vertebrae
- Trial name
- NCT07122791
- Testing
- Home Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul University - Cerrahpasa
Dialysis; Complications
Effect of Modifying Magnesium Concentration in Citrate-enriched Dialysate on Serum Magnesium Levels
Individuals with ESKD and treated with hemodialysis have a high mortality risk. Associative studies suggest a relationship between serum magnesium concentration and mortality risk.
- Trial name
- OMAGOD-1 (NCT07565779)
- Testing
- A - Dialysate magnesium 0.75, B - Dialysate magnesium 1.00 mmol/L
- Where
- 4 sites in Belgium
- Volunteers
- 54 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Liver Cirrhosis
Gabapentin in Treatment of Muscle Cramps in Patients With Liver Cirrhosis
Muscle cramps markedly affect the quality of life in cirrhotic patients with no highly effective drug. Quinine was suggested for treatment of patients with muscle cramps in patients with liver cirrhosis.
- Trial name
- NCT02642484
- Testing
- Gabapentin, Calcium Carbonate
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Tanta University
Back Pain, Acute Pain
Tolperisone in Acute Muscle Spasm of the Back
This is a double-blind, randomized, placebo-controlled, parallel group study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered as multiple doses three times a day (TID) in approximately 400 male and…
- Conditions
- Back Pain, Acute Pain, Back Spasm Upper Back, Back Strain
- Trial name
- STAR (NCT03802565)
- Testing
- Tolperisone
- Where
- 43 sites in United States
- Volunteers
- 415 people
- Sponsor
- Neurana Pharmaceuticals, Inc.
Cardiac Catheterization, Spasm
Topical Radial Artery Vasodilation
The aim of the study is to facilitate radial artery access for cardiac catheterization. The investigators hypothesize that topical nitroglycerin and lidocaine will reduce radial artery spasm.
- Trial name
- NCT01155167
- Testing
- Nitroglycerin and lidocaine
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of California, San Francisco
Spasm
Noninvasive Cardiac Imaging in Vasospastic Angina Korean Registry (NAVIGATOR)
With regard to the characteristics of spasm segment, had been clearly described by other invasive imaging methods including intravascular ultrasound and optical coherence tomography.
- Trial name
- NAVIGATOR (NCT03570671)
- Testing
- Spasm positive, Spasm negative
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Dong-A University
Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease
Levetiracetam (Keppra) is used to treat partial onset seizures. Its biological effects suggest it might also be useful in treating 3 aspects of human motor neuron diseases (MNDs) for which no effective therapy exists: cramps…
- Conditions
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis, Progressive Muscular Atrophy
- Trial name
- NCT00324454
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Esophageal Motility Disorders
Endolumenal Partial Myotomy for Esophageal Motility Disorders
Achalasia and esophageal spasm are primary esophageal motility disorders where the lower esophageal sphincter fails to relax in response to swallowing with no well understood underlying cause.
- Trial name
- NCT01302301
- Testing
- Per oral endolumenal myotomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Oregon Clinic