Clinical trials: Muscle Wasting
Muscle Function, Handgrip Strength Test
Muscle Assessment in Women Who Have Undergone Roux-en-Y Gastric Bypass Surgery
The purpose of this study is to assess muscle function in women at least two years after being submitted to Roux-en-Y Gastric Bypass Surgery and compare with a control group
- Trial name
- FUBA (NCT02811393)
- Testing
- Assess muscle function
- Where
- Chile
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Chile
Sarcopenia
Dose Response of Whey and Soy Protein Ingestion With and Without Resistance Exercise in Elderly Men
When we age, we lose muscle. It is not exactly clear why this happens, but we do know that this muscle loss can increase health risks and lead to health problems. Lifting weights (i.e.
- Trial name
- NDC (NCT01062711)
- Testing
- Whey or soy protein
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- McMaster University
Sarcopenia
Effects of Low-volume HIIT Versus MICT on Physical Performance in Older Adults With Possible Sarcopenia
Background: Sarcopenia is an age-related geriatric syndrome characterized by progressive loss of muscle mass and function. Before the diagnosis of sarcopenia, a "possible sarcopenia" stage has been proposed recently…
- Trial name
- NCT05790863
- Testing
- Ergometer cycling
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
TRIAL READY (Clinical Trial Readiness)
This study, being conducted under the auspice of the CReATe Consortium, will enroll patients with ALS and related disorders as well as healthy controls, with the goal of facilitating clinical validation of leading…
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, ALS-Frontotemporal Dementia, Primary Lateral Sclerosis
- Trial name
- NCT03912987
- Where
- 3 sites in United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- University of Miami
Healthy Male Volunteers Over 65
Investigating the Digestibility, Bioavailability and Utilisation of Varied Combined Protein Sources in Older Males Using a Dual Stable Isotope Tracer Technique
By 2020, over 20% of the UK population will be over 65 years of age, dramatically increasing pressure on health and social care. Muscle mass is a strong predictor of healthy ageing and longevity.
- Trial name
- NCT07038655
- Testing
- Randomised 20g Protein Supplement
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sarcopenia in Elderly, Dynapenia
Reduction in Resistance Training Volume and Neuromuscular Adaptations in Older Adults
The goal of this clinical trial is to evaluate how reducing resistance training volume affects neuromuscular adaptations in older adults aged 60 to 70 years.
- Trial name
- NCT07046130
- Testing
- Resistance Training
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sarcopenia, Obesity
Citrulline Supplementation Combined With Exercise: Effect on Muscle Function in Elderly People (CITEX Study)
The main objective of this study is to determine if oral supplementation of Citrulline, when combined with HIIT, can produce significant changes in body composition, muscle quality, muscle metabolism and functional capacity in…
- Trial name
- CITEX (NCT02417428)
- Testing
- Citrulline, Exercise, without exercise
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Muscle Atrophy
Protein Ingestion and Skeletal Muscle Atrophy
The effect of different protein intakes on skeletal muscle atrophy during short term unilateral leg immobilisation.
- Trial name
- NCT03797781
- Testing
- Lower limb immobilisation (leg brace) with varying levels of protein intake
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Lumbar Disc Herniation, Lumbar Degenerative Disease
Multivariate Analysis and Machine Learning Model Risk Prediction of Recurrent Pain After PLIF Surgery for Degenerative Lumbar Spine Disease At Long-term Follow-up
The study was a clinical retrospective study designed to investigate risk factors for long-term recurrent pain after PLIF in patients with lumbar degenerative disease and to improve patient outcomes
- Conditions
- Lumbar Disc Herniation, Lumbar Degenerative Disease, Sarcopenia
- Trial name
- NCT06622356
- Testing
- MRI with Eovist
- Where
- China
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Hao Liu
Sarcopenia, Muscle Weakness
Functional Changes and Power Training in Older Women.
Extending quality of life and attenuating functional decline is paramount in older adults. This study investigates the effects of low-intensity power-training in older women and its effects on functional outcomes.
- Trial name
- F-POW (NCT02530723)
- Testing
- power training
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Overweight With Indications for Weight Loss
Optimizing Body Composition for Function in Older Adults
The purpose of this pilot study is to compare two strategies intended to improve the health of overweight older adults by improving body composition.
- Trial name
- NCT00315146
- Testing
- Pioglitazone, Resistance exercise training to maximize muscle power, Hypocaloric diet
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Muscle Synthesis
Effects of Protein Blends on Muscle Protein Synthesis in Healthy Older Adults
During aging there is a tendency for muscle protein synthesis (growth) to become less efficient and the resulting consequence leads to reduced muscle mass (sarcopenia) which can affect strength and mobility.
- Trial name
- NCT01847261
- Testing
- Soy Dairy Protein Blend, Positive Control (Dairy Whey Protein)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DuPont Nutrition and Health
Older Adults Without Any Specific Clinical Condition
Essential Amino Acid Supplementation Enhances Post-prandial Amino Acid Availability Following a Standard-protein Breakfast in Older Adults
Healthy older adults and those who have acute and chronic conditions suffer from reduced protein intake and are at risk of developing both chronic and acute sarcopenia.
- Trial name
- NCT07754760
- Testing
- Essential amino acid supplement
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Urinary Incontinence, Sarcopenia
Association Between Sarcopenia and Urinary Incontinence And Effect Of Physical Activity Among Over 50 Years Old Adults
As far as the investigators know, until this moment no research has investigated the prevalence of Sarcopenia in both sexes in Hungary.
- Trial name
- NCT05313360
- Where
- Hungary
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Sarcopenia
Blood Flow, Muscle Regeneration and Sarcopenia
Due to the rapid aging of the population, sarcopenia is among the greatest challenges facing the health care system over the next quarter century.
- Trial name
- NCT01035060
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Florida
Sarcopenia
Role of the Gut Microbiome on Lean Mass and Physical Function in Older Adults
The investigators recently published significant associations between circulating gut bacteria-related metabolites with lean and skeletal muscle mass and with measures of physical function in older adults, evidence that suggests…
- Trial name
- NCT02811445
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cirrhosis of the Liver, Ascites
Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis: A Point-of-Care Tool for Predicting Complications and Sarcopenia in Limited Resource Settings
The goal of this observational study is to learn how liver cirrhosis affects the diaphragm, the main muscle used for breathing, in adults.
- Conditions
- Cirrhosis of the Liver, Ascites, Pleural Effusion Disorder, Hepatocellular Carcinoma (HCC)
- Trial name
- NCT07667608
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hepatic Encephalopathy
Microbiota, Sarcopenia, and Hepatic Encephalopathy Change in Cirrhotic Patients Before and After Rehabilitation
Through this plan, it will provide many benefits to patients with liver cirrhosis complicated with sarcopenia and/or hepatic encephalopathy, their family members, and the government in Taiwan: 1.
- Trial name
- NCT06040814
- Testing
- Rehabilitation Training
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Sarcopenic Obesity, Sarcopenia
Lifestyle Modifications for the Treatment of Sarcopenic Obesity
This study evaluates the addition of a high-protein energy-restricted diet to exercise in the treatment of sarcopenic obesity in people aged 65 and over.
- Conditions
- Sarcopenic Obesity, Sarcopenia, Obesity
- Trial name
- NCT02379026
- Testing
- Protein Drink/Diet, Exercise, Vitamin D3
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Sarcopenia
Protein Supplementation Intervention for Improving Muscle Mass and Physical Performance in Older People With Sarcopenia
Background: Declines in muscle mass and strength are expected with aging, but physical inactivity and low protein intake have been suggested as risk factors of sarcopenia.
- Trial name
- NCT04516421
- Testing
- Protein supplementation
- Where
- 3 sites in Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Asia University