Clinical trials: Muscle Wasting
Sarcopenia, Diabetes Mellitus
Glucose Metabolism, Muscle Mass/Function and Inflammation in the Elderly
A thorough characterization of glucose metabolism and "inflammaging" in elderly subjects will help determine to what extent each of these factors affects muscle mass/function and contributes to age-related muscle wasting.
- Trial name
- NCT02426073
- Where
- 2 sites in Italy
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sarcopenia
Regime for Vitamin D Maintenance in Post-Operative Patients
Vitamin D plays a significant part calcium and phosphate haemostasis, thus, intrinsically critical for bone health. Increasing evidence also reveal that insufficient serum vitamin D levels also result in poor muscle health with…
- Trial name
- D-ECISIVE (NCT06708741)
- Testing
- Vitamin D
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Rotator Cuff Tears, Motor Imagery
Does MI Have a Therapeutic Role in Arthroscopic Rotator Cuff Repair?
Objective: The aim of this study is to investigate the effect of motor imagery on muscle activity, pain, and function in arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Motor Imagery, Muscle Activity, Atrophy, Muscular
- Trial name
- NCT05670080
- Testing
- Motor Imagery, Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Sarcopenia
The Benefits of Hemp Protein Supplementation During Resistance Training
Forty physically active men and women aged 18-45y will take part in an 8-week resistance training program, randomized (double blind) 1:1 into each of two groups.
- Trial name
- NCT02529917
- Testing
- Hemp powder, Soy Powder
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Aging, Sarcopenia
Assessing the Impact of Age, and a Short-term High-intensity Interval Training (HIIT) on Skeletal Muscle Mass and Mitochondrial Activity
The goal of this interventional study is to learn about the role of mitochondrial function in healthy aging, and then go on and assess the role of a home-based exercise program on the changes seen.
- Trial name
- Mi-HIIT (NCT05934760)
- Testing
- High intensity interval training (HIIT), Resistance based training (RET)
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Aging, Muscle Loss
Protein Intake and Step Reduction in Older Adults
Sarcopenia, the loss in muscle mass with age, is associated with several negative health outcomes including cancer, stroke, cardiovascular disease and diabetes.
- Trial name
- DRI (NCT03285737)
- Testing
- Whey, Collagen
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- McMaster University
Malnutrition, Sarcopenia
Health and Nutrition Status of Chinese Elderly
This study is aiming to understand the prevalence and risk factors related to malnutrition and sarcopenia in Chinese elderly.
- Trial name
- NCT02089906
- Where
- 3 sites in China
- Volunteers
- 2,834 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Obesity, Cardiovascular Disease
IMPACT: Inactivity Monitoring and Physical Activity Controlled Trial
As individuals age, their physical activity decreases and sedentary time increases. Even small changes in these two behaviors can greatly decrease risks for several major health problems, including cardiovascular disease…
- Conditions
- Obesity, Cardiovascular Disease, Cancer, Diabetes
- Trial name
- IMPACT (NCT01869348)
- Testing
- Monitor intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Sarcopenia, Atrophy
Leucine Supplementation in Elderly Men
In the present study the investigators aim to determine whether leucine supplementation can augment muscle mass and strength and improve body composition in healthy elderly men
- Conditions
- Sarcopenia, Atrophy, Aging
- Trial name
- NCT00807508
- Testing
- leucine
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Spinal and Bulbar Muscular Atrophy, Kennedys Disease
Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)
Background: SBMA is an inherited chronic disease. It affects males in mid to late adulthood. It causes slowly progressive weakness of muscles and hand tremors. Researchers want to learn more about the effects of SBMA.
- Conditions
- Spinal and Bulbar Muscular Atrophy, Kennedys Disease, Motor Neuron Disease
- Trial name
- NCT04944940
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Muscle Loss, Fractures
Musculoskeletal Effects of Bicarbonate
With aging, men and women develop a mild and progressive metabolic acidosis. This occurs as a result of declining renal function and ingestion of acid-producing diets.
- Conditions
- Muscle Loss, Fractures, Osteoporosis, Age Related, Fall Injury
- Trial name
- NCT01475214
- Testing
- potassium bicarbonate
- Where
- United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Tufts University
Sarcopenia in Elderly
The Effect of Adding Elastic Resistance Training in Routine Physical Exercise on Walking Speed of Elderly People With Sarcopenia in Griya Wreda Jambangan, Surabaya
The goal of this randomized clinical trial is to learn whether adding elastic resistance training (ERT) to routine physical exercise can improve walking speed in older adults aged 60 years or older with sarcopenia living at Griya…
- Trial name
- NCT07859969
- Testing
- Elastic Resistance Training, Routine Physical Exercise
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Colorectal Cancer, Exercise, Aerobic
Pedaling at a Low-Moderate Intensity During Chemotherapy Administration
The purpose of this study is to evaluate the feasibility of completing a low-moderate intensity pedaling session concurrent to chemotherapy treatment for colorectal cancer.
- Conditions
- Colorectal Cancer, Exercise, Aerobic, Chemotherapy, Chemotherapeutic Toxicity
- Trial name
- NCT04258969
- Testing
- Pedaling
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Myotonic Muscular Dystrophy
Study of Muscle Wasting and Altered Metabolism in Patients With Myotonic Dystrophy
OBJECTIVES: I. Examine the interrelationships between muscle wasting (phenotype), the degree of myotonic dystrophy (DM) gene expression (genotype) in patients with DM. II. Characterize the insulin resistance in these patients.
- Trial name
- NCT00004769
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Spinal Muscular Atrophy
Prenatal Carrier Screening for Spinal Muscular Atrophy Among Thai Pregnant Women
Spinal muscular atrophy (SMA) prenatal carrier screening is recommended by American College of Medical Genetics (ACMG) and American College of Obstetrics and Gynecology (ACOG).
- Trial name
- NCT04859179
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy
A Study of the Effect of BIIB023 on Muscle Atrophy in Healthy Male Volunteers
The primary objective of this study is to determine whether muscle atrophy induced by immobilization of the lower limb can be attenuated by BIIB023 in healthy male volunteers.
- Trial name
- NCT01943513
- Testing
- BIIB023
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biogen
Sarcopenia
Cardiorespiratory Training and Ventilatory Muscle Strength
The cardiorespiratory training can increase muscle strength ventilatory.
- Trial name
- RMS (NCT01912482)
- Testing
- Cardiorespiratory training, ventilatory training
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Gama Filho
Sarcopenia
Milk and Milk-produce to Counteract the Loss of Muscle Mass and Function in Exercising Older Adults.
This project evaluates the use of different types of proteins from various food sources after an exercise session, on muscle mass and physical capacity in aged sarcopenic men (who have low muscle mass).
- Trial name
- PRO (NCT01883674)
- Testing
- Resistance training
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Sarcopenia, Diagnosis
Evaluating SARC-F, SARC-CalF, and Calf Circumference as Diagnostic Tools for Sarcopenia in Thai Older Adults: Results From a Nationwide Study
As the elderly population grows, musculoskeletal disorders, including sarcopenia, have become a critical area of study due to their association with falls and fractures.
- Trial name
- NCT06558617
- Testing
- SARC-F Questionnaire, Calf Circumference Measurement, SARC-CalF Questionnaire
- Where
- Thailand
- Volunteers
- 2,543 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Hip Injuries, Muscular Atrophy
Strength and Strength-ratio of Hip Rotator Muscles at Soccer Players
At this investigation we want to find out whether there is a difference in muscle strength of the internal and external rotation hip muscles between soccer players and non-soccer players caused by typical movement patterns seen…
- Conditions
- Hip Injuries, Muscular Atrophy, Dysfunction
- Trial name
- NCT01821183
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland