Clinical trials: Muscle Weakness
Paresis, Lumbar Disc Herniation
Validation of a Methodology Using Isometric Dynamometer for Ankle STrength Assessment to Quantify LDH-induced Paresis
Lumbar disc herniation (LDH) is a common condition that may cause lower limb motor weakness (paresis), particularly affecting ankle dorsiflexion and plantarflexion.
- Trial name
- VAST-LDH (NCT07763522)
- Testing
- Strength test validity and reliability
- Where
- Finland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Stroke, Cerebrovascular Accident
Spinal Plasticity to Enhance Motor Retraining After Stroke
The objective of this project is to study the effects of an emerging noninvasive neuromodulation strategy in human stroke survivors with movement-related disability.
- Conditions
- Stroke, Cerebrovascular Accident, Hemiparesis
- Trial name
- NCT03645122
- Testing
- Paired corticospinal-motoneuronal stimulation (PCMS)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Muscle Weakness, Smartphone Addiction
Effect of Scapular Stabilization Exercises on Scapular Muscles Strength and Kyphosis Index in Smartphone Users
This study will be conducted to investigate the effect of scapular stabilization exercises on scapular muscles strength (serratus anterior, lower fibers of trapezius, rhomboid major and minor), pain intensity level and kyphosis…
- Trial name
- NCT05437367
- Testing
- Scapular Stabilization exercises, Postural correction exercises
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Muscle Weakness
Respiratory Muscle Training in Subacute Stroke Patients
This study is divided for development in two complementary work packages justified by the need to incorporate new strategies to optimize rehabilitation outcomes in stroke patients.
- Trial name
- RETORNUS (NCT02125760)
- Testing
- Inspiratory Muscle Training (IMT), High-intensity IMT
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Neck Pain, Range of Motion
Comparative Effect of Neck Isometrics and Deep Cervical Flexion Exercises on Neck Pain Among Breastfeeding Females.
Neck pain is a common complaint among breastfeeding females, potentially attributed to sustained postures and muscle imbalance. Breastfeeding females experiencing neck pain, aged between 18-40 years, will be recruited through…
- Conditions
- Neck Pain, Range of Motion, Muscle Weakness, Breastfeeding
- Trial name
- NCT06877728
- Testing
- Neck isometric exercises: 3 times weekly for 6 consecutive weeks (18 sessions)
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Muscle Weakness
Mitochondria and Muscle Health in Elderly
The aim of this study is to characterize the relation between skeletal muscle mitochondrial metabolism and muscle health in elderly, physically compromised humans.
- Trial name
- ELMIH (NCT03666013)
- Where
- Netherlands
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Muscle Weakness
The Effect of Dynamic and Rigid Tape Application on the Asymmetry of the Lower Limbs
This is a prospective randomized three brachial, single-blinded, placebo-controlled trial, which aims at assessing the impact of the gluteal muscle taping with a dynamic tape and a non-elastic tape on the activation of the…
- Trial name
- NCT04345224
- Testing
- Dynamic tape, Rigid tape
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- John Paul II University in Biała Podlaska
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Sarcopenia, Muscle Weakness
Functional Changes and Power Training in Older Women.
Extending quality of life and attenuating functional decline is paramount in older adults. This study investigates the effects of low-intensity power-training in older women and its effects on functional outcomes.
- Trial name
- F-POW (NCT02530723)
- Testing
- power training
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Neonatal Brachial Plexus Palsy
Forced Lefthandedness in Neonatal Brachial Plexus Palsy (NBPP) Children
The aim of the project is to assess the neurophysiological and functional consequences of forced lefthandedness in a population with right neonatal brachial plexus palsy (NBPP).
- Trial name
- NBPP (NCT04376372)
- Testing
- Functional testing, Magnetic resonance imaging, Electromyography
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Old Age; Debility, Muscle Weakness
Probiotic-Muscle Study
This study will examine the effect of probiotic supplementation (Bacillus coagulans) on muscle protein synthesis in older adults in response to a plant-based diet.
- Conditions
- Old Age; Debility, Muscle Weakness, Protein Deregulation, Protein Deposition
- Trial name
- NCT04297111
- Testing
- Probiotic
- Where
- Ireland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Cerebral Palsy, Hemiparesis; Poststroke/CVA
Characterization of Muscle Activity During a Surface EMG-controlled Rehabilitation Game
The aim of this pilot study is to evaluate muscular activity during a single session of surface electromyography controlled exergame (muscle activation, number of contraction…) in cerebral palsy kids, hemiparetic adults and…
- Conditions
- Cerebral Palsy, Hemiparesis; Poststroke/CVA, Healthy (Controls)
- Trial name
- CONTRACTIV-1S (NCT07838688)
- Testing
- Surface electromyography (sEMG)-controlled rehabilitation game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Nutrition, Healthy, Muscle Weakness
A Randomized Control Trial of Hinex Jelly on the Changes in Muscle Quality and Quantity
Taiwan is about to enter a super-aged society in 2025. The health problems of the elderly are getting more and more attention. Among these geriatric issues, sarcopenia is an important issue.
- Conditions
- Nutrition, Healthy, Muscle Weakness, Elderly
- Trial name
- NCT05917353
- Testing
- Hinex Jelly
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Poor Performance Status, Muscle Weakness
SR-WBV Training for Frail Elderly in the Skilling up Stage
This randomized controlled study aims to examine long term effects in the skilling up phase over 4 weeks on physical functional performance and strength of mechanical SR-WBV and dance therapy intervention in a frail elderly…
- Trial name
- NCT01704976
- Testing
- SR-WBV
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Stroke, Biofeedback
Biofeedback Gait Training by Target Biomechanical Parameters in the Early Recovery Period of Stroke
Single-blinded controlled clinical trial. Biofeedback training courses based on target biomechanical gait parameters are being studied.
- Conditions
- Stroke, Biofeedback, Gait, Hemiplegic, Gait Training
- Trial name
- TargetGait (NCT06299943)
- Testing
- Biofeedback gait training by biomechanical target parameter
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Frailty, Muscle Weakness
The Effects of Functional Power Training on Frail and Pre-frail Community - Dwelling Older Adults in Singapore
To investigate the efficacy of a 12-week Functional Power Training (FPT) program in pre-frail and frail community-dwelling older adults in Singapore for the management of physical frailty.
- Trial name
- NCT04438876
- Testing
- Functional Power Training, Usual care
- Where
- Singapore
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Geriatric Education and Research Institute
Muscle Weakness, XLH
Muscle Abnormalities in Children With XLH
XLH rickets is a rare disease with muscle weakness. Fat parameters such as IMAT and intraMAT could be increased in this disease.
- Trial name
- MDmuscleXLH (NCT05312086)
- Testing
- MRI
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Brain-injury
Effectiveness of Aquatic Theraphy in Spasticity: Watsu and Halliwick
Treatment with ACD patients will be carried out through the application of aquatic therapies, being the Halliwick Concept and the Watsu Method together with a time of immersion in hot water.
- Trial name
- NCT05151497
- Testing
- Experimental group:Halliwick + Método Watsu, Control group:Halliwick
- Where
- 3 sites in Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Spastic Paresis, Stroke
GOAT (Gait Observation of Achilles Tendon)
The purpose of this study is to evaluate the mechanical properties of the Achilles tendon (stiffness, length, volume) and the force production capacities of the gastrocnemius medialis muscle in patients with spastic paresis…
- Conditions
- Spastic Paresis, Stroke, Spinal Cord Injury
- Trial name
- GOAT (NCT07467382)
- Testing
- 3D Gait Analysis, Ultrasound, Dynamometry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital