Clinical trials: Muscle Weakness
Muscle Loss, Muscle Weakness
Enhancing Muscle Health and Metabolism in Pre-frail Middle-aged and Older Adults
To evaluate the effects of protein-enriched soup plus exercise on muscle mass and muscle strength. Besides, the investigators use the valued-based healthcare standard set as well as the Center for Epidemiological…
- Trial name
- NCT05828134
- Testing
- protein-enriched soup
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Muscle Weakness
Mitigating Neural Hypoexcitability and Weakness During Disuse in Women
Clinical trial The goal of this clinical trial is to learn how muscle weakness and atrophy develop during short periods of arm immobilization and whether a type of exercise called cross-education can help reduce these effects in…
- Trial name
- MiND (NCT07166198)
- Testing
- Wrist immobilization, Resistance training, Resistance training rehabilitation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Post-stroke Hemiparetic Patients (at Least 6 Months Post Stroke), Age Between 18-75 Years
Evaluation of the Effects of Rehabilitation Using the "Wii" on Upper Limb Kinematics in Chronic Stroke Patients.
The purpose of this study is to evaluate changes in strategies of hemiparetic upper limb movement in chronic stroke patients following rehabilitation using the "Nintendo Wii".
- Trial name
- WII (NCT01806883)
- Testing
- WII Rehabilitation, Traditional rehabilitation
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pelvic Floor Muscle Weakness, Dysmenorrhea
Core Muscle Strength in Women with Primary Dysmenorrhoea
The aim of this study is to compare core muscle strength, core muscle activations, and pelvic tilt angles in women with and without Primary Dysmenorrhea (PD).
- Conditions
- Pelvic Floor Muscle Weakness, Dysmenorrhea, Posture
- Trial name
- NCT06854900
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Derya Azim
Stroke, Hemiparesis
Quadriceps Muscle Activity and Gait Kinematics in Patients With Post-Stroke Stiff-Knee Gait Compared With Healthy Controls
Stiff-knee gait (SKG) is a frequent gait abnormality in people with post-stroke hemiparesis and is characterized by insufficient knee flexion during the swing phase of walking.
- Trial name
- FW QUADRI (NCT07857967)
- Where
- Luxembourg
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Frédéric Chantraine
Physiology
Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation
Patients with COPD have lower cortical activation and higher cortical inhibitory levels. The purpose of this study is to test the reversibility the lower cortical activation by counterbalancing the increased cortical inhibitory…
- Trial name
- NCT03368703
- Testing
- Anodal transcranial direct-current-stimulation
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Intensive Care Unit-acquired Weakness, Artifical Intelligence
AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness
The aim of this observational case-control study is to investigate, whether artificial intelligence can detect ultrasound-derived imaging characteristics typical for intensive care unit-acquired weakness.
- Conditions
- Intensive Care Unit-acquired Weakness, Artifical Intelligence, Ultrasound
- Trial name
- ACTIVATE (NCT06765551)
- Testing
- Neuromuscular Ultrasound
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Sarcopenia, Muscle Weakness
SARCOPEDIA - Sarcopenia Diagnostics in Aging Medicine
Musculoskeletal aging is one of the major responsibilities and challenges for public health. In particular, sarcopenia correlates with an increased risk of falls and increased morbidity and mortality.
- Conditions
- Sarcopenia, Muscle Weakness, Frailty
- Trial name
- SARCOPEDIA (NCT05263596)
- Testing
- dual x-ray absorptiometry, body impedance analysis, muscle strength measurements, ultrasound
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Department of Geriatric Medicine FELIX PLATTER
Hemiparesis, Stroke
Transforming Robot-mediated Telerehabilitation: Citizen Science for Rehabilitation
The purpose of this study is to advance upper limb robot-mediated tele-rehabilitation for patients recovering from stroke by empowering them through active science participation.
- Trial name
- NCT03096262
- Testing
- Citizen Science intervention using kinect
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pelvic Floor Muscle Weakness, Strength
Assessment of Pelvic Floor Strength Variables in Female Nulliparous Athletes
Functional Fitness Training (FFT) is a modality that seeks to improve physical fitness and performance within several functional tasks by conducting a variety of training activities such as aerobic and metabolic conditioning…
- Conditions
- Pelvic Floor Muscle Weakness, Strength, Muscle Tone
- Trial name
- FFT-PFM (NCT06626841)
- Testing
- Pelvic floor muscles contractile capacity and activation
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Proprioceptive Postural Control, Respiratory Disorders
Proprioceptive Postural Control and Diaphragm Paresis
Proprioceptive weighting changes may explain differences in postural control performance. In addition, the respiratory movement has a disturbing effect on postural balance.
- Conditions
- Proprioceptive Postural Control, Respiratory Disorders, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01505556
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- KU Leuven
Stroke
VNS-induced Corticospinal Plasticity
The goal of this study is to learn more about the connections between the brain, spinal cord, and muscles and how these connections can be strengthened after neurological injury.
- Trial name
- NCT04088565
- Testing
- Paired-Associative Stimulation (PAS), Vagus Nerve Stimulation (VNS)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pelvic Floor Disorders, Pelvic Floor Muscle Weakness
Association Between Physical Activity Level ，Overall Muscle Strength and Pelvic Floor Muscle Function in Women.
In this study, it is assumed that grip strength is associated with pelvic floor muscle strength. And the outcome of pelvic floor function can be predicted by referring to the status of pelvic floor muscle strength through the…
- Trial name
- NCT05318768
- Where
- China
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Anterior Cruciate Ligament Injury, Muscle Weakness
WEakness and Atrophy: isoKinetic With Surface Electromyography Assessment in ACL Surgery
An assessment of the effect of surgical anterior cruciate ligament (ACL) on thigh muscles is critical to the improvement of knee rehabilitation and preservation.
- Trial name
- WEAKNESS (NCT03200678)
- Testing
- isokinetic assessment
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Aging
The UNCODE Study: Unravelling the Neural Contributors Of Dynapenia in Elders
The UNCODE Study seeks to better identify the neurological causes of muscle weakness associated with advancing age. The main study consists of 4 laboratory-based testing sessions that involve testing muscle strength and physical…
- Trial name
- NCT02505529
- Testing
- Resistance Exercise Training, Mental Imagery
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ohio University
Muscle Weakness
Functional Change With MMS
Evaluate the safety and efficacy of magnetic muscle stimulation (MMS) of abdominal muscle.
- Trial name
- FMS (NCT04506502)
- Testing
- The ZELTIQ System
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Down Syndrome, Hemiparesis
Kinematic Analysis of Manual Dexterity
The following study aims to standardize the instrumented BBT for the objective evaluation of upper limb joint kinematics using MoCap on a population of healthy subjects between 4 and 18 years of age.
- Conditions
- Down Syndrome, Hemiparesis, Healthy Subjects
- Trial name
- SUPERFUN (NCT07875127)
- Testing
- Inertial Measurement Unit and Box and Block test
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Pelvic Floor Muscle Weakness, Stress Urinary Incontinence
Effects of Neuromuscular Pelvic Realigning Exercises on Pelvic Floor Muscle Function in Continent SubjectS
The goal of this research study is to investigate the effect of a new neuromuscular approach for correcting pelvic alignment and improving pelvic floor muscle function.
- Conditions
- Pelvic Floor Muscle Weakness, Stress Urinary Incontinence, Pelvic Asymmetry
- Trial name
- NCT03975686
- Testing
- neuromuscual realigning exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of North Georgia
MULTIPL SCLEROSİS
Comparison of Frailty, Physical Fitness Parameters, and Irisin Levels Between Patients With Multiple Sclerosis and Healthy Volunteers
Multiple Sclerosis (MS) is a chronic immune-mediated and neurodegenerative disease of the central nervous system that often affects young adults and is more common in women.
- Trial name
- NCT07521982
- Where
- Turkey (Türkiye)
- Volunteers
- 782 people, healthy volunteers welcome
- Sponsor
- Baskent University
Thumb Osteoarthritis, Muscle Atrophy or Weakness
Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA
In this study, investigators aimed to investigate the morphometric parameters tenar muscles and joint configuration in patients with trapeziometacarpal osteoarthritis (TMC OA) osteoarthritis stages, thenar muscle parameters…
- Trial name
- NCT04913935
- Testing
- Muscle-Skeleton Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University