Clinical trials: Muscle Weakness | Patient
Stroke, Hemiparesis
IpsiHand System for Rehabilitation of the Arm and Hand After Stroke
This study aims to assess whether the NeuroLutions Upper Extremity Rehabilitation System (known as IpsiHand) will help stroke patients regain strength and functional movements in their arm.
- Trial name
- NCT04123808
- Testing
- IpsiHand Treatment
- Sponsor
- Columbia University
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stroke, Hemiparesis of the Upper Limb Following Stroke
Neurophysiological and Behavioral Effects of Combining Transcranial Direct Current Stimulation (tDCS) and Modified-Constraint Induced Movement Therapy (mCIMT)
This clinical trial aims to evaluate the effect of different types of tDCS modulation with mCIMT in improving affected upper-limb motor function for stroke patients.
- Conditions
- Stroke, Hemiparesis of the Upper Limb Following Stroke, Stroke Rehabilitatiom
- Trial name
- tDCS and mCIMT (NCT06786000)
- Testing
- Anodal tDCS combined with mCIMT, Cathodal tDCS combined with mCIMT, Bihemispheric tDCS combined with mCIMT
- Where
- Saudi Arabia
- Volunteers
- 300 people
- Sponsor
- King Saud University
Mechanical Ventilation, Critical Illness
Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)
This clinical study aims to compare the effects of conventional physical therapy alone versus conventional physical therapy combined with neuromuscular electrical stimulation (NMES) in patients admitted to the ICU and undergoing…
- Conditions
- Mechanical Ventilation, Critical Illness, Intensive Care Unit Patients, Muscle Weakness Condition
- Trial name
- MOVCARE (NCT07188350)
- Testing
- Conventional Physical Therapy, Neuromuscular Electrical Stimulation (NMES)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Hospital Moinhos de Vento
Knee Osteoarthritis, Knee Arthritis
Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy
This is a randomized control trial to determine if there is a measurable change in voluntary quadriceps activation, RTD, pain, and function before and after a single session of manual physical therapy.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity
- Trial name
- NCT04234282
- Testing
- Manual Physical Therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jennifer Moreno Clinic
Stroke, Upper Extremity Paresis
Telerehabilitation for Hand Function in Stroke Patients
Stroke is a leading cause of adult disability worldwide, with upper limb impairment significantly reducing independence. Traditional outpatient rehabilitation poses challenges for patients with mobility limitations, financial…
- Conditions
- Stroke, Upper Extremity Paresis, Hand Functions
- Trial name
- TeleStroke-PK (NCT07666906)
- Testing
- Telerehabilitation with Conventional Therapy, Conventional Outpatient Rehabilitation
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- University of Faisalabad
End-Stage Renal Disease, Muscle Weakness
Anabolic Steroids and Exercise in Hemodialysis Patients
This is a study to find out whether an exercise program during dialysis or a drug called nandrolone decanoate can increase muscle size and strenght in patients on dialysis.
- Trial name
- NCT00250536
- Testing
- nandrolone decanoate, resistance exercise training
- Volunteers
- 80 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Multiple Sclerosis, Muscle Weakness
Foot Muscles Training in Sclerosis
The study tries to assess the efficacy of an 8-week IFM training programme on stability in patients diagnosed with Multiple Sclerosis
- Conditions
- Multiple Sclerosis, Muscle Weakness, Training Group, Sensitivity
- Trial name
- NCT06665607
- Testing
- Intrinsic Mucle Training
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Inés Llamas-Ramos
Neuromuscular Electrical Stimulation, ICU Acquired Muscle Weakness
Neuromuscular Electrical Stimulation in Mechanically Ventilated Patients
Intensive care unit-acquired muscle weakness (ICUAMW) is a common problem following an ICU admission and is associated with prolonged hospitalization, delayed weaning and increased mortality.
- Trial name
- NCT05465291
- Testing
- Exercise group, Neuromuscular Electrical Muscle Stimulation group, Neuromuscular Electrical Muscle Stimulation and Exercise group
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Damanhour University
Critical Illness, ICU-acquired Weakness
Beyond Voluntary Effort: Reliability and Validity of Magnetic Femoral Nerve Stimulation for Assessing Quadriceps Strength in Critically Ill Patient
Intensive care unit-acquired weakness (ICU-AW) is a common complication of critical illness and can negatively affect recovery and long-term physical functioning.
- Trial name
- TWITCH FORCE (NCT07891273)
- Testing
- Magnetic Femoral Nerve Stimulation
- Volunteers
- 33 people
- Sponsor
- Daniel Langer
Stroke, Paresis
Enhanced Reality for Hemiparetic Arm in the Stroke Patients
The researchers found that enhanced reality developed for the first time in the word by us had a synergistic or additive effect on brain plasticity in patients without central nervous system injury.
- Conditions
- Stroke, Paresis, Mirror Movement
- Trial name
- NCT03270852
- Testing
- Enhanced reality, No Enhanced reality
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Ulsan University Hospital
Hospital Mobility, Mobility Limitation
An INtervention TO Improve MOBility of Older Hospitalized Patients
Low mobility during an acute care hospitalization is very frequent, particularly among older patients, and associated with adverse outcomes, such as persistent functional decline, institutionalization and death.
- Conditions
- Hospital Mobility, Mobility Limitation, Life-Space, Functional Status
- Trial name
- INTOMOB (NCT05639231)
- Testing
- INTOMOB intervention
- Where
- 4 sites in Switzerland
- Volunteers
- 383 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Sepsis, Critical Illness
MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients
The goal of this clinical trial is to learn if a new medical device that sends electrical signals to the thigh muscles is safe and easy to use for people in the ICU (Intensive Care Unit) who are at risk of losing muscle strength.
- Conditions
- Sepsis, Critical Illness, ICU-acquired Muscle Weakness, ICU-acquired Weakness
- Trial name
- ICUAW (NCT07362862)
- Testing
- Electrical Muscle Stimulation System
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Health Discovery Labs
Muscle Weakness, ICU-acquired Weakness
Improving Muscle Function in Nutritionally at Risk, Elderly Patients
The investigators propose to conduct a randomized, control trial of β-hydroxy-β-methylbutyrate (HMB) supplementation in elderly patients (≥65 years of age) with acute respiratory failure, who are identified at high risk for…
- Trial name
- NCT03071354
- Testing
- HMB protein supplement (3g), Nutritional Supplement
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Spasticity as Sequela of Stroke, Stroke
Prevalence of Postural Patterns of Upper Extremity.
A high number of patient with stroke develops spasticity of the upper extremity, this clinical sign of damage of 1 motoneuro (MN), causes postures and patterns of abnormal movement, due to the hyperexcitability of the MN and the…
- Conditions
- Spasticity as Sequela of Stroke, Stroke, Upper Extremity Paresis
- Trial name
- Patterns (NCT03588832)
- Testing
- Evaluation Upper Extremity patterns.
- Where
- Chile
- Volunteers
- 600 people
- Sponsor
- Universidad de La Frontera
Thumb Osteoarthritis, Muscle Atrophy or Weakness
Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA
In this study, investigators aimed to investigate the morphometric parameters tenar muscles and joint configuration in patients with trapeziometacarpal osteoarthritis (TMC OA) osteoarthritis stages, thenar muscle parameters…
- Trial name
- NCT04913935
- Testing
- Muscle-Skeleton Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stroke, Physical Disability
Robotic Versus Conventional Therapy For Post-Stroke Hand Motoric Recovery
This clinical trial aims to compare the effectiveness of Robotic versus conventional mirror therapy among post-stroke patients. The main questions it aims to answer are: Effectiveness of both interventions in hand motoric…
- Conditions
- Stroke, Physical Disability, Upper Extremity Paresis
- Trial name
- NCT06155058
- Testing
- SYREBO, Conventional Mirror Method
- Where
- 3 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Stroke, Upper Extremity Paresis
Rhythmic Initiation vs Isometric Training for Arm Recovery After Stroke
Stroke is a leading cause of long-term disability worldwide. Many stroke survivors experience persistent weakness, loss of motor control, and poor coordination in their upper limb, which limits their ability to perform daily…
- Trial name
- RIITSTROKE (NCT07598435)
- Testing
- Rhythmic Initiation (PNF technique), Isometric Resistance Training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Faisalabad
Upper Extremity Weakness, Stroke
A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis
The primary purpose of this study is to establish that application of a Sequential Compression Device (SCD) and lower extremity (LE) sleeve applied to a hemi-paretic upper extremity is safe.
- Trial name
- NCT05535257
- Testing
- Sequential Compression Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Pelvic Floor Muscle Weakness, Pelvic Pain
Movement-Based Pelvic Health Education for Women in Underserved Communities
It is essential to provide the community with evidenced-based care to optimize healthcare outcomes; more specifically, women in underserved communities undergoing health disparities in rehabilitation.
- Trial name
- PHEd (NCT05569694)
- Testing
- Movement-based pelvic health education
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education