Clinical trials: Muscle Weakness | Patient
Weakness, Muscle
Muscular Ultrasound and Production of ICUAW
Skeletal muscle weakness is a common complication of acute respiratory failure, shock and other manifestations of critical illness or injury.
- Trial name
- MUICUAW (NCT04864093)
- Testing
- muscular ultrasound
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- University of Milan
Vocal Cord Dysfunction, Vocal Cord Paralysis
Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure
The goal of this prospective, observational study is to evaluate for the presence of vocal fold motion impairment (VFMI) in the children admitted to the pediatric intensive care unit on noninvasive positive pressure ventilation…
- Conditions
- Vocal Cord Dysfunction, Vocal Cord Paralysis, Vocal Cord Paresis, Recurrent Laryngeal Nerve Palsy
- Trial name
- NCT06406725
- Testing
- Point-of-Care Ultrasound of the Airway
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Spastic Hemiplegic Cerebral Palsy, Upper Extremity Paresis
The Effects of Upper Extremity Robotic Rehabilitation in Children With Spastic Hemiparetic Cerebral Palsy
Aims: To investigate the effects of upper extremity robotic rehabilitation on upper extremity skills and functional independence level in patients with hemiparetic Cerebral Palsy (hCP).
- Conditions
- Spastic Hemiplegic Cerebral Palsy, Upper Extremity Paresis, Robotic Rehabilitation
- Trial name
- NCT06352762
- Testing
- Conventional physiotherapy, Robotic Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Izmir Bakircay University
Mechanically Ventilated Patients
Early Directed Physical Therapy in the Management of Mechanically Ventilated Patients in a Medical Intensive Care Unit
To study all ICU patients with an independent baseline functional status, who experience a critical illness requiring intubation and mechanical ventilation, evaluating the role of protocol-directed, early physical and…
- Trial name
- NCT00322010
- Testing
- early PT OT
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Chicago
Hemiparesis, Balance
Effect of Incorporating Perceptual Learning Into Plantar Hardness Discrimination on the Risk of Falling and Muscle Torque in Patients With Hemiplegia
Hemiplegia, a common stroke sequela, significantly impairs motor function, leading to balance issues and increased fall risk. Traditional rehabilitation methods often fall short in fully restoring function.
- Trial name
- NCT07077837
- Testing
- Study Group, Control
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Al-Zaytoonah University of Jordan
End-Stage Renal Disease, Muscle Weakness
Anabolic Steroids and Exercise in Hemodialysis Patients
This is a study to find out whether an exercise program during dialysis or a drug called nandrolone decanoate can increase muscle size and strenght in patients on dialysis.
- Trial name
- NCT00250536
- Testing
- nandrolone decanoate, resistance exercise training
- Volunteers
- 80 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Muscle Weakness, Atrophy, Muscle
Muscle Stem Cell Quality in Atrophy
The goal of this clinical trial is to compare the quality of mesoangioblasts isolated from various patient groups suffering from muscle atrophy.
- Conditions
- Muscle Weakness, Atrophy, Muscle, Cachexia, Sarcopenia
- Trial name
- ATROMAB (NCT06077734)
- Testing
- In vitro analyse
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- Maastricht University Medical Center
ACL Injury, Muscle Weakness
Nordic Hamstring Exercise After ACL Reconstruction Reconstruction
Anterior cruciate ligament (ACL) injuries constitute a significant portion of major knee joint injuries sustained by young, active individuals, and significantly increase risk for long-term disability.
- Conditions
- ACL Injury, Muscle Weakness, Neuromuscular Manifestations
- Trial name
- NCT05738200
- Testing
- Nordic Hamstring Exercise
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Toledo
Hematologic Malignancy, Muscle Weakness
Effects of NMES and Exercise in Hematological Cancer
Physical activity levels of adult hematologic cancer patients are deficient. The resulting physical inactivity causes fatigue, muscle loss, and deterioration in physical performance values.
- Trial name
- NCT04755465
- Testing
- Neuromuscular Electrical Stimulation, Structured Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Acibadem University
Chronic Obstructive Pulmonary Disease Severe, Muscle Weakness
Additional Manual Therapy Over Inspiratory Muscle Training in COPD
The benefits of inspiratory muscle training(IMT) in patients with chronic obstructive pulmonary disease(COPD) were reported.But in severe COPD patients, benefit from IMT may be limited.There is need for further research in new…
- Trial name
- NCT04533516
- Testing
- Manual therapy technics, Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
Stroke, Ischemic, Acute Pain
Effects of Mirror Therapy Versus Fine Motor Activities on Hand Function in Chronic Stroke Patients.
to compare the effects of the Mirror therapy and fine motor activities on hand function in chronic stroke patients
- Conditions
- Stroke, Ischemic, Acute Pain, Weakness, Muscle
- Trial name
- NCT05506826
- Testing
- fine motor activities, conventional therapy and mirror therapy
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease
Involvement of Nervous System in Muscle Weakness in COPD Patients
The purpose of this study is to determine whether nervous system alterations and motor drive failure can contribute to muscle weakness in COPD during voluntary movement.
- Trial name
- DesCoM-1 (NCT01679782)
- Where
- France
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Stroke, Upper Extremity Paresis
Functional Recovery in Stroke Patients With Task-Specific Robot-Aided Arm Therapy
The goal of this study is to determine whether task-oriented, robot-aided therapy is more effective than conventional physical and occupational therapy at promoting functional recovery of the affected arm in chronic hemiparetic…
- Trial name
- NCT00719433
- Testing
- robot therapy (ARMin), conventional therapy
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University of Zurich
Thymidine Kinase 2 Deficiency
An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency
This is a Phase 2 prospective open-label treatment study of the safety and efficacy of doxecitine and doxribtimine in study participants with thymidine kinase 2 (TK2) deficiency who participated in the retrospective study…
- Trial name
- Continuation (NCT03845712)
- Testing
- doxecitine and doxribtimine
- Where
- 8 sites in United States, Israel and 1 more
- Volunteers
- 47 people
- Sponsor
- UCB BIOSCIENCES, Inc.
Stroke
Effect of Upper Extremity Rehabilitation Using Immersive Virtual Reality in Chronic Stroke Patients.
The study aimed to investigate the effect of exergames using virtual reality with head mounted device on motor recovery of upper extremities in chronic stroke patients.
- Trial name
- NCT05148052
- Testing
- Virtual reality exergames, Conventional occupational therapy
- Where
- 3 sites in South Korea
- Volunteers
- 15 people
- Sponsor
- Seoul National University Hospital
Stroke, Arm
Enhancing Recovery of Arm Movement in Stroke Patients
Many people who have had a stroke have problems recovering the use of their affected arm and these problems may persist for a long time.
- Conditions
- Stroke, Arm, Paresis
- Trial name
- ENHANCE (NCT02725853)
- Testing
- tDCS, personalized practice, non-personalized practice
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University
Statin Intolerance
Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity
The purpose of this study is to gain insight into the side-effects of statin consumption, and assess the ability of epicatechin (a compound in dark chocolate) to counteract or reverse these changes.
- Trial name
- NCT02490527
- Testing
- Pure epicatechin capsules (50mg), Simvastatin (40mg)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pompe's Disease
Prevalence of Pompe's Disease in Respiratory Clinics
Pompe's disease is a very rare condition which causes weakness of the respiratory muscles and may therefore cause symptoms of breathlessness or even respiratory failure, requiring the use of a ventilator at night.
- Trial name
- PURF (NCT02527239)
- Testing
- Prospective observational study
- Volunteers
- 400 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Covid19, Diaphragm Injury
Respiratory Muscle Assesment in COVID-patients Without Hospitalization
Fatigue and exercise intolerance after survived COVID-19-infection might be related to weakness of the respiratory muscles. The aim of the project is to measure respiratory muscle function and strength in our respiratory…
- Trial name
- RMA-COVID-19 (NCT06105450)
- Testing
- Comprehensive assessment of respiratory muscle function.
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- RWTH Aachen University
Stroke, Activities, Motor
INTENSIVE TREATMENT WITH ROBOTIC PLUS VIBRATION IN STROKE
The Amadeo® Manual Robotic System (Tyromotion GmbH, Graz, Austria) is designed for rehabilitative treatment of the hand and fingers providing robot-assisted exercise for the finger flexors and extensors.
- Conditions
- Stroke, Activities, Motor, Quality of Life, Sensitivity
- Trial name
- VIBRAROBOT (NCT04762940)
- Testing
- Robotic, Vibration
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Rey Juan Carlos