Clinical trials: Muscular Disease
Pulmonary Sarcoidosis
The Effect of Inspiratory Muscle Training and Breathing Exercises Combined With Upper Extremity and Trunk in Patients With Sarcoidosis
This is an educational work. Thirty patients with pulmonary sarcoidosis will be included in the study and randomly selected into two training groups.One group will receive home inspiratory muscle training (IMT) for 15 minutes…
- Trial name
- physio (NCT04173689)
- Testing
- Threshold IMT, breathing exercises combined with upper extremity and trunk
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul University - Cerrahpasa
PARKINSON DISEASE (Disorder), Rigidity
Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD
Axial rigidity and loss of spinal mobility commonly observed in Parkinson's disease (PD) lead to postural deformities and substantial reductions in trunk flexibility.
- Conditions
- PARKINSON DISEASE (Disorder), Rigidity, Temporomandibular Disorders (TMDs), Mobility
- Trial name
- NCT07850674
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Sarcopenia, Hepatocellular Carcinoma
Comparison of Serum Myokine Dosages and Imaging Methods in the Evaluation of Sarcopenia in Patients With Hepatocellular Carcinoma
It is known that some substances present in the blood, called 'myokines,' influence muscle loss. Some may accelerate this loss, while others may prevent it. Inflammatory substances in the blood can also contribute to muscle loss.
- Trial name
- Myomachia (NCT06475118)
- Testing
- Dynamometry measurement, myokine dosing, sarcopenia calculation
- Where
- France
- Volunteers
- 139 people
- Sponsor
- CHU de Reims
Fibromyalgia
Study To Assess The Clinical Benefit Of Droxidopa And Droxidopa/Carbidopa In Subjects With Fibromyalgia
A correlation between increased norepinephrine concentration in the central nervous system (CNS) and a decrease in fibromyalgia pain has been suggested in clinical studies.
- Trial name
- FMS201 (NCT01323374)
- Testing
- Droxidopa, Carbidopa, Droxidopa/carbidopa
- Where
- 7 sites in United Kingdom
- Volunteers
- 122 people
- Sponsor
- Chelsea Therapeutics
Fibromyalgia
Pilot Study of Warm Acupuncture in Treatment of Cold-sensitive Fibromyalgia Syndrome
Non-pharmaceutical therapies, such as acupuncture, hydrotherapy, and meditative exercises (such as Qigong (including Tai Chi and Ba-Duan-Jin), have been shown to reduce pain and improve physical function.
- Trial name
- NCT05228990
- Testing
- warm acupunctrue
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Old Age; Atrophy
The Effect of a Combined Personalized Nutritional Intervention and a Personalized Graded Activity Functional Training Program on Physical Performance in Hospitalized Older Patients, Compared to Usual Care
This project aims to improve physical performance in older patients, by offering a personalized combined nutritional intervention with a physical activity training program.
- Trial name
- FITFOOD (NCT05413616)
- Testing
- FITFOOD lifestyle intervention
- Where
- Netherlands
- Volunteers
- 136 people
- Sponsor
- Radboud University Medical Center
Prediabetes, Obesity
Veterans Achieving Weight Loss and Optimizing Resilience-Using Protein
Diabetes is a major health concern in obese older Veterans, especially in those who are African American. The negative impact of diabetes on muscle and physical function contributes to metabolic as well as physical decline and is…
- Trial name
- VALOR-UP (NCT03835416)
- Testing
- Foods rich in high quality protein
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development
Non-Muscle Invasive Bladder Cancer
A Phase II Trial of Bicalutamide in Patients Receiving Intravesical BCG for Non-muscle Invasive Bladder Cancer
This is a phase II randomized controlled clinical trial comparing standard induction BCG versus bicalutamide and standard induction BCG among patients with non-muscle invasive bladder cancer.
- Trial name
- BicaBCa (NCT05327647)
- Testing
- Bicalutamide, Control Arm
- Where
- 7 sites in Canada
- Volunteers
- 160 people
- Sponsor
- CHU de Quebec-Universite Laval
Type2diabetes, Heart Failure With Reduced Ejection Fraction
Ketones, SGLT2, HFrEF
The study team will examine the effects of elevated plasma ketone levels following initiation of SGLT2 inhibitor therapy in high-risk type 2 diabetes mellitus (T2DM) individuals with heart failure (HF) with reduced ejection…
- Trial name
- NCT06229678
- Testing
- Empagliflozin 25 MG Oral Tablet, Acipimox 250 Mg Oral Capsule
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Fibromyalgia, Covid-19 Fear
The Effects of Covid-19 Pandemic on The Patients With Fibromyalgia
The investigators planned to analyze the effect of Covid-19 fear and anxiety on the daily life, sleep quality and depression-anxiety levels of fibromyalgia patients.
- Conditions
- Fibromyalgia, Covid-19 Fear, Covid-19 Anxiety, Daily Life
- Trial name
- NCT04686578
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Multiple Sclerosis
Multiple Sclerosis and Heavy Progressive Resistance Training
The purpose of the present investigation is to determine whether MS patients can tolerate and benefit from heavy progressive resistance training.
- Trial name
- NCT00381576
- Testing
- Resistance training
- Where
- 2 sites in Denmark
- Volunteers
- 36 people
- Sponsor
- University of Aarhus
Dislocation, Total Hip Arthroplasty
Preoperative Gluteal Muscle Atrophy: A Silent Predictor of THA Dislocation.
This study looks at how fat buildup in hip muscles relates to hip osteoarthritis and less favorable recovery after hip replacement surgery.
- Conditions
- Dislocation, Total Hip Arthroplasty, Muscle Degeneration
- Trial name
- NCT06571604
- Testing
- Dislocation, No dislocation
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
INSTRUMENT ASSISTED SOFT TISSUE MOBILIZATION
Role of Soft Tissue Therapy in Plantar Fasciitis
Plantar Fasciitis (PF) is a frequently and commonly reported heel pain present in every age with multifactorial etiology. It is the most common reason for constant heel pain in adults affecting both young active and older…
- Trial name
- NCT05256433
- Testing
- Group-A, Group-B
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Ziauddin University
Tendinopathy
Tracking of Red Blood Cells Using Super Resolution Ultrasound in Persons With Healthy or Overuse Injured Tendons
The goal of this observational study is to test whether a new ultrasound method, called SUper Resolution ultrasound imaging of Erythrocytes (SURE), can image the small blood vessels found in tendons of persons with a tendon…
- Trial name
- SURE-TEND (NCT06142747)
- Testing
- Super-Resolution Ultrasound Imaging of Erythrocytes (SURE)
- Where
- Denmark
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Health Literacy, Middle Aged
Health Literacy-Based Multifactorial Program for Adults With Sarcopenia
Sarcopenia is a common age-related condition characterized by the progressive loss of muscle mass and function, which may lead to reduced physical performance, disability, and poorer quality of life.
- Conditions
- Health Literacy, Middle Aged, Elderly (People Aged 65 or More), Exercise Therapy
- Trial name
- NCT07654478
- Testing
- Multicomponent Intervention
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Mechanical Ventilation
Study of Muscle Effects of BYM338 in Mechanically Ventilated Patients
The purpose of this study is to evaluate the effect of BYM338 on muscle mass and function in Group III failure to wean patients, as compared to placebo controls.
- Trial name
- NCT01868685
- Testing
- BYM338
- Sponsor
- Novartis Pharmaceuticals
Sarcopenia, Frailty
Oral Nutritional Supplementation With HMB Enhance Muscle Quality in Sarcopenic Surgical Patients
Aims: Clinical frailty severely impacts the physical, functional and physiological reserves necessary for the recovery after surgery.
- Trial name
- HEROS (NCT05344313)
- Testing
- Ensure Plus Advance
- Where
- Singapore
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Aging
The Eggs and actiVity in hEalth agiNg Pilot (EVEN-P) Trial in Older Persons
Two of the most effective lifestyle-based approaches to reduce the risk of adverse health events and enhance quality of life with aging are exercise and a healthy diet.
- Trial name
- EVEN-P (NCT04264013)
- Testing
- Exercise, Exercise plus diet (egg)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
COVID-19 Acute Respiratory Distress Syndrome
Rehabilitation of Critically Ill Patients With SARS-CoV-2 Variants in ICU With Limited Resources
Acute rehabilitation in critically ill patients can improve post-intensive care unit (post-ICU) physical function. Scientific evidence has considered neuromuscular electrical stimulation (NMES) as a promising approach for the…
- Trial name
- NCT05450120
- Testing
- Functional Rehabilitation, Neuromuscular Electrical Stimulation
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Federal de Sao Carlos
Piriformis Syndrome
Effectiveness of Instrument Assisted Soft Tissue Mobilization in Management of Piriformis Syndrome
This study aims to assess the effectiveness of IASTM on pain, ROM, Disability and Quality of life among Piriformis Syndrome patients.
- Trial name
- NCT06406023
- Testing
- Conventional treatment, Instrument assisted soft tissue mobilization
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University