Clinical trials: Muscular Hypertrophy
Resistance Training, Muscle Hypertrophy
High- and Low-Load Resistance Training
The goal of this clinical trial is to learn whether low-load resistance training performed to muscle failure can produce similar increases in muscle size and strength as high-load resistance training in healthy untrained young…
- Trial name
- NCT07412600
- Testing
- Low-load resistance training (30% 1RM), High-load resistance training (75% 1RM)
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Bruxism, Myofascial Pain
Ultrasonographic Evaluation of Masseter Muscle Changes After Botulinum Toxin Injection in Bruxism Patients
This prospective pilot study aimed to evaluate short-term clinical and ultrasonographic changes in the masseter muscle following botulinum toxin injection in patients with bruxism.
- Conditions
- Bruxism, Myofascial Pain, Masseter Muscle Hypertrophy
- Trial name
- NCT07545200
- Testing
- Botulinum Toxin A (Botox )
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Pancreatic Cancer
Impact of Hypertrophy-oriented Resistance Training on Muscle Mass and Quality of Life in Patients With Unresectable Pancreatic Cancer
To determine the efficacy of a 12-week supervised, hypertrophy-oriented strength training program in preserving skeletal muscle mass, physical function, and quality of life in patients with unresectable pancreatic cancer compared…
- Trial name
- HY-PANC (NCT07470268)
- Testing
- supervised, hypertrophy-oriented strength training program
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Europea de Madrid
Adenoid Hypertrophy, Masseter Muscle
Evaluation of the Effect of Adenoid Hypertrophy on the Masseter Muscle in Children: A Comparative Ultrasonographic Study
The goal of this observational study is to evaluate the effect of adenoid hypertrophy on the masseter muscle in children aged 3 to 8 years.
- Conditions
- Adenoid Hypertrophy, Masseter Muscle, Malocclusion
- Trial name
- NCT07094581
- Testing
- USG
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Melis AKYILDIZ
Proteomics, Exercise
Dynamic Proteomics and Integrated Rates of Muscle Protein Synthesis During an Acute Period of Loading and Unloading
Skeletal muscle plays several different roles in the promotion and maintenance of health and well-being. The loss of muscle mass that occurs with aging, chronic muscle wasting diseases, and physical inactivity puts people at an…
- Conditions
- Proteomics, Exercise, Atrophy, Disuse, Hypertrophy
- Trial name
- HYPAT (NCT04514744)
- Testing
- Knee bracing, Unilateral Resistance Exercise Training
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster University
Masseter Muscle Hypertrophy
Xeomin Cosmetic in the Management of Masseter
The goal of this study was to evaluate the efficacy and safety of two injection techniques in the management of masseteric hypertrophy using Xeomin Cosmetic.
- Trial name
- NCT03376464
- Testing
- Xeomin Cosmetic
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Skeletal Muscle
Leucine or Protein Supplementation and Resistance Training
The purpose of this study was to determine the effects of L-leucine (LEU) or different protein supplements standardized to LEU (~3.0 g/serving) on changes in body composition, strength, and histological attributes in skeletal…
- Trial name
- MPS (NCT03501628)
- Testing
- L-leucine + maltodextrin, Whey protein concentrate, Hydrolyzed whey protein concentrate
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Auburn University
Hypertrophy, Muscle Strength
Effects of Phosphatidic Acid on Strength and Hypertrophy
There are indications that phosphatidic acid (PA) supplementation is capable of enhancing gains in strength and muscle mass in response to strength training, although the literature is still incipient and controversial.
- Trial name
- NCT04277364
- Testing
- phosphatidic acid supplementation, Strength training
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Obesity, Overfeeding
Overeating Different Fats and Influence on Muscle Mass and Body Fat Accumulation
To investigate metabolic and molecular response to fatty acid-specific overfeeding in overweight subjects, in relation to changes in ectopic fat, lean tissue mass and insulin sensitivity
- Conditions
- Obesity, Overfeeding, Muscle Mass, Body Composition
- Trial name
- LIPOGAIN-2 (NCT02211612)
- Testing
- PUFA-group, SFA-group
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Skeletal Muscle Hypertrophy
The Effects of Heavier- and Lighter-load Resistance Training on Arm and Leg Muscle Mass in Young Adult Women
When you perform weightlifting, your body makes new proteins within your muscle. These new proteins can increase the size of the fibers within your muscle to make your muscle larger, a process called hypertrophy.
- Trial name
- FHALL (NCT04547972)
- Testing
- Higher-load resistance training, Lower-load resistance training
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hypertrophic Cardiomyopathy
Study to Determine if Atorvastatin Reduces Size and Stiffness of Muscle in the Left Ventricle of the Heart
The purpose of this study is to determine if a drug called atorvastatin will reduce the size and stiffness of the muscle in the left ventricle of the heart.
- Trial name
- NCT00317967
- Testing
- Atorvastatin
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Calgary
Muscle Atrophy, Disuse Atrophy (Muscle) of Lower Leg
The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation
It is well known that periods of weight training lead to increases in skeletal muscle size and strength. In contrast, periods of inactivity such as bed rest or immobilization result in losses of skeletal muscle size and strength.
- Trial name
- HYPAT (NCT03046095)
- Testing
- Unilateral Resistance Exercise, Immobilization
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- McMaster University
Aging, Muscle Hypertrophy
Resistance Exercise Volume and Hypertrophic Response Variability in Elderly
The study aimed to investigate the effects of resistance training volume manipulation on whole muscle hypertrophy among non-responders and responders to a low resistance training dose (single-set).
- Trial name
- NCT06718712
- Testing
- Lower body resistance training
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- University of Sao Paulo General Hospital
Sarcopenia, Atrophy
Resistance Training in Elderly
In the present study the investigators aim to determine whether protein supplementation can augment the response to a 12 week resistance training program in healthy elderly men.
- Conditions
- Sarcopenia, Atrophy, Aging
- Trial name
- NCT00744094
- Testing
- protein drink, Resistance training
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Resistance Training, Blood Flow Restriction (BFR) Training Effects
Strength Training With and Without Blood Flow Restriction on Shoulder Muscle Strength in Healthy Adults
The goal of this clinical trial is to compare two types of shoulder strength training: low-load training with blood-flow restriction (BFR) and high-load training without BFR. The study includes healthy adults.
- Trial name
- NCT07186231
- Testing
- Low-load resistance training with Blood flow Restriction, High-load resistance training.
- Where
- Portugal
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Alice Maria da Costa Carvalhais
Obesity
Comparison of 1 vs 3 Sets of Resistance Training on Muscular Hypertrophy
This study is designed to investigate the effects of two levels of resistance weight training on body composition, energy expenditure, and energy intake in men and women. The weight training will take about one hour to complete.
- Trial name
- NCT01107691
- Testing
- Amount of resistance offered in training
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Type 2 Diabetes
RESIST! Blood-flow Restriction Resistance Training for Improving Insulin Sensitivity in Type 2 Diabetes
The study aims to investigate the metabolic and cardiovascular effects of classical resistance training with high loads and blood-flow restricted training (BFRT) with low loads in individuals with type 2 diabetes over 12 weeks.
- Trial name
- RESIST (NCT04222231)
- Testing
- Blood-flow restriction resistance training, Classical resistance training
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Menstrual Cycle, Resistance Exercise
Menstrual Cycle Phase Based Training
The primary purpose of this study is to employ state-of-the-art methods to fill current knowledge gaps on the effects of the menstrual cycle on resistance exercise training adaptations.
- Trial name
- MCPBT (NCT05936424)
- Testing
- Unilateral Resistance Exercise Leg, Non-Exercise Control Leg
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University
Skeletal Muscle Hypertrophy
Post-exercise Recovery After Dietary Protein Ingestion in Healthy Young Men (Meat-Milk Study)
Rationale: The consumption of dietary protein immediately after exercise is necessary to maximally stimulate muscle protein synthesis rates (24, 37). Recent work suggests that the type of protein consumed (e.g., animal vs.
- Trial name
- Meat-Milk (NCT01578590)
- Testing
- Lean minced meat (beef)
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Muscle Hypotrophy, Exercise Performance
Resistance Training Adaptations and Caffeine Intake
This parallel-group, randomized, double-blind, placebo-controlled trial investigates the effects of three different caffeine supplementation strategies on resistance training-induced adaptations in 120 caffeine-naive, inactive…
- Conditions
- Muscle Hypotrophy, Exercise Performance, Muscle Strength, Adaptation
- Trial name
- NCT07410195
- Testing
- Caffeine (Constant Daily Dose), Caffeine (Escalating Dose), Caffeine (Training Days Only)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa