Clinical trials: Muscular Weakness
Thumb Osteoarthritis, Muscle Atrophy or Weakness
Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA
In this study, investigators aimed to investigate the morphometric parameters tenar muscles and joint configuration in patients with trapeziometacarpal osteoarthritis (TMC OA) osteoarthritis stages, thenar muscle parameters…
- Trial name
- NCT04913935
- Testing
- Muscle-Skeleton Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Mechanical Ventilation Complication, Muscle Weakness Condition
Effects of NMES in Critically Ill Patients
Muscle wasting occurred early and rapidly in critically ill patients. Early therapeutic strategies to either maintain muscle structure and function should be encouraged.
- Conditions
- Mechanical Ventilation Complication, Muscle Weakness Condition, Covid19
- Trial name
- NUMBERNMES (NCT04382378)
- Testing
- neuromuscular electrical stimulation
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Escola Superior de Ciencias da Saude
Muscular Dystrophies, Scapular Dyskinesis
Evaluation of a Textile Scapula Orthosis
Shoulder instability due to muscle weakness is a common problem in disorders of the upper extremities. During arm motion, the scapula acts as a dynamic base for the humeral head.
- Conditions
- Muscular Dystrophies, Scapular Dyskinesis, Muscular Dystrophy, Facioscapulohumeral, Muscle Weakness
- Trial name
- ScapOrthosis (NCT04154098)
- Testing
- Scapula orthosis assistance, Manual scapula assistance, No assistance
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 8 people
- Sponsor
- Swiss Federal Institute of Technology
End Stage Liver DIsease, Chronic Liver Failure
The Early Strength Training Program in Post-transplant Liver Cases
Liver transplantation (LT) is a current life-saving procedure performed as an open-abdominal surgery for patients with end-stage liver diseases (ESLD).
- Conditions
- End Stage Liver DIsease, Chronic Liver Failure, Liver Transplant Disorder, Muscle Loss
- Trial name
- NCT04546048
- Testing
- Strength Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Memorial Hospital Groups
Exercise, Detraining
Effects of COVID-19 Lockdown in Exercising Early Postmenopausal Women
While "conditioning" by exercise training has been widely evaluated, the available literature on "passive deconditioning" (i.e. forced deconditioning) is predominately limited to studies with or with almost complete mechanical…
- Conditions
- Exercise, Detraining, Muscle Weakness, Muscle Atrophy
- Trial name
- NCT04420806
- Testing
- HIT-exercise
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Mechanical Ventilation, Expiratory Muscle
Expiratory Muscle Function in Critically Ill Ventilated Patients
Inspiratory muscle weakness develops rapidly in ventilated critically ill patients and is associated with adverse outcome, including prolonged duration of mechanical ventilation and mortality.
- Conditions
- Mechanical Ventilation, Expiratory Muscle, Critical Illness, Muscle Atrophy or Weakness
- Trial name
- EMFIC (NCT04333186)
- Testing
- Data from ultrasound measurements
- Where
- Netherlands
- Volunteers
- 113 people
- Sponsor
- Amsterdam UMC, location VUmc
Muscle Atrophy or Weakness, Muscle Contraction
Core Exercises Effects on Muscle Imbalances
This study aims in investigating the effects of a core muscles' strengthening program on core muscles' atrophy and contraction ability.
- Conditions
- Muscle Atrophy or Weakness, Muscle Contraction, Core Stability
- Trial name
- NCT04450615
- Testing
- Core stability
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Athanasios Ellinoudis
MUSCULAR AQUIRED WEAKNESS, Bioelectrical Impedance Analysis
The BIA and MUS in the Detection of Nutritional Status in Critically Ill Patients
Critically ill patients are characterized by wide variations in their carbohydrate, lipid, and protein metabolism. Such variations can lead to increase in their energy requirement with accelerated protein catabolism and…
- Conditions
- MUSCULAR AQUIRED WEAKNESS, Bioelectrical Impedance Analysis, Muscular Ultrasound
- Trial name
- BUS (NCT03924232)
- Where
- Italy
- Volunteers
- 97 people
- Sponsor
- University of Milan
Critical Illness, Muscle Atrophy or Weakness
Redefining Survivorship: POWER to Maximize Physical Function for Survivors of Critical Illness
Patients surviving critical illness experience significant skeletal muscle dysfunction and weakness. Muscle atrophy suffered during critical illness has a long-term impact on the functionality and mobility of these individuals.
- Trial name
- POWER (NCT04058977)
- Testing
- Power training
- Where
- United States
- Sponsor
- Kirby Mayer
Metabolomics, Critical Care
Metabolomics Study on Intensive Care Acquired Muscle Weakness in Polytrauma
In this mono-center pilot trial, polytrauma patients admitted to intensive care will be included. Investigators are going to take blood and muscle samples at respecified time points to do metabolic, histological and molecular…
- Conditions
- Metabolomics, Critical Care, Critical Illness, Critical Illness Myopathy
- Trial name
- MIRACLE II (NCT03819959)
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Technical University of Munich
Critical Illness, Respiratory Failure
Treatment of Muscle Weakness in Critically Ill Patients
Patients who are admitted to the intensive care unit and require mechanical ventilation frequently develop profound respiratory and limb muscle weakness.
- Conditions
- Critical Illness, Respiratory Failure, Myopathy, Weakness
- Trial name
- NCT02247895
- Testing
- Electrical stimulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Gerald Supinski
Muscle Weakness, Muscle Loss
Power Training on Muscle Quality and Functional Capacity in Women Aged 65-75.
Muscle power training has proven to be an effective intervention to prevent sarcopenia and frailty in old people. In the last decade, new concepts related to the functionality of old people have been generated, such as muscle…
- Trial name
- NCT04315662
- Testing
- Muscle power training with velocity loss (VL) of 10%, Muscle power training with velocity loss (VL) of 30%
- Where
- Colombia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Muscle Loss, Muscle Weakness
Impact of Increased Protein Density Diet to Muscle Mass and Strength Among Mid-aged and Older Adults
The subjects of this intervention program are mainly based on community-dwelling mid-aged and older adults. The investigator's program will provide meals containing different proportionated protein.As this project is a double…
- Conditions
- Muscle Loss, Muscle Weakness, Fragility
- Trial name
- NCT03784456
- Testing
- 25% protein, 15% protein
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Yang Ming Chiao Tung University
Critical Illness, Intensive Care (ICU) Myopathy
Muscle Dysfunction in Critical Illness
Patients surviving critical illness suffered significant skeletal muscle dysfunction and weakness that impacts their functionality and independence.
- Conditions
- Critical Illness, Intensive Care (ICU) Myopathy, PICS, Muscle Weakness
- Trial name
- NCT03717831
- Testing
- Observational study of standard of care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Kentucky
Weakness, Muscle
Bed Rest and Muscle Strength in ICU: Interest in the Early Association of NEMS With Cyclo-ergometer Mobilization
Muscles atrophy and weakness are common in intensive care units, their origin is multifactorial. Passive then active mobilization with cyclo-ergometer have shown to improve functional abilities and limit muscle weakness among…
- Trial name
- AFMPR (NCT03987997)
- Testing
- Early association of electrical muscle stimulation with cyclo-ergometer
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Muscular Weakness
Training Intrinsic Foot Muscles
The foot intrinsic muscles are increasingly targeted in foot and ankle rehabilitation. The exercises are often difficult to learn initially.
- Trial name
- NCT03670563
- Testing
- Short foot exercise protocol, Short foot exercise plus NMES
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Cushing Syndrome, Acromegaly
Muscle in Acromegaly and Cushing's Syndrome
Cushing's syndrome (CS) and acromegaly determine myopathy and muscle weakness which persist long-term after control of hormone excess.
- Trial name
- MAC (NCT03673761)
- Testing
- MRI, dual-energy, x-ray absorptiometry, muscle ultrasounds, blood testing
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Muscular Weakness
Can Blood Flow Restriction Therapy Improve Strength for Shoulder External Rotators Better Than Exercise Alone
The purpose of this study is to evaluate the ability of blood flow restriction therapy to improve strength of shoulder muscles during the sidelying external rotation (ER) exercise versus a control group who only performs the…
- Trial name
- NCT03815760
- Testing
- Blood Flow Restriction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- George Fox University
Cancer, Cancer Cachexia
Effects of WB-EMS and Dietetic Treatment on Cancer Patients
This study evaluates the effects of a 12-week whole-body electromyostimulation (WB-EMS) training combined with individualized nutritional support on body composition, muscle strength and function and quality of life of patients…
- Conditions
- Cancer, Cancer Cachexia, Weight Loss, Muscle Loss
- Trial name
- NCT02293239
- Testing
- Whole-Body Electromyostimulation (WB-EMS)
- Where
- Germany
- Volunteers
- 278 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Cancer, Cancer Cachexia
Effects of WB-EMS and Specific Dietary Supplements on Cancer Patients
Patients suffering from cancer often experience a loss of muscle mass and strength during disease and its therapy. Muscle wasting is the main characteristic of the so-called cancer cachexia syndrome and responsible for many…
- Conditions
- Cancer, Cancer Cachexia, Weight Loss, Muscle Loss
- Trial name
- NCT03151291
- Testing
- β-hydroxy-β-methylbutyrate (HMB), L-carnitine (LC), Eicosapentaenoic acid (EPA)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Erlangen-Nürnberg Medical School