Clinical trials: Musculoskeletal Complication
Osteoarthritis, Dislocations
Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Surgery is a common treatment type for damaged joints, tendons and nerves in the upper limb where conservative measures are inappropriate or have failed.
- Conditions
- Osteoarthritis, Dislocations, Inflammatory Arthritis, Rotator Cuff Tear
- Trial name
- NCT03573765
- Testing
- Shoulder arthroplasty, Elbow arthroplasty, Hand and wrist arthroplasty
- Volunteers
- 8,308,821 people
- Sponsor
- University of Oxford
Erector Spinae Plane Block, Wound Infiltration
Postoperative Pain in Lumbar Disc Surgery
This study included 46 patients who underwent lumbar disc herniation surgery under general anesthesia. After the operation, US-guided ESPB was performed on Group E, and WI was performed on Group W.
- Conditions
- Erector Spinae Plane Block, Wound Infiltration, Lumbar Disc Herniation, Postoperative Pain
- Trial name
- Pain (NCT06844747)
- Testing
- erector spinae plane block(ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Orthopedic Disorders, Surgical Site Infection
Preoperative Decolonization and Surgical Site Infections - a Prospective Randomized Trial
Surgical site infections are a major postoperative complication and are mostly due to colonization with endogenous germs, like Staphylococcus aureus, Staphylococcus epidermidis or Propionibacterium acnes.
- Trial name
- DECO-SSI (NCT02560155)
- Testing
- Mupirocin 2% nasal ointement, Chlorhexidine sol 4%
- Where
- Switzerland
- Volunteers
- 1,300 people
- Sponsor
- Lindenhofgruppe AG
Orthopedic Disorder, Post Operative Pain
Nonpharmacological Management of Postoperative Pain in Children
The 3 non-pharmacological methods of online gaming, cold application, and placebo were chosen to reduce postoperative pain in children undergoing orthopedic and traumatology surgery.
- Trial name
- NCT05893680
- Testing
- Group to play online games, Group that received cold application, Group that played an online game and received cold application at the same time
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- İlke Karabıyık
Infant, Premature, Diseases
Calcium (ca),Phosphorus( P) and 25-hydroxyvitamin D(25OHD)] in Infants Born ≤ 32 PMA Gestational Weeks (GA)
It has not yet been established the optimal dose of vit. D for preterm infants in Poland. It is not known what dose of vit. D will provide the correct concentration of vit.
- Trial name
- Ca-P (NCT03691896)
- Testing
- Cholecalciferol 400, Cholecalciferol 800, Cholecalciferol 1200
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Centre of Postgraduate Medical Education
Lumbar Disc Herniation, Lumbar Discogenic Pain
Comparing General Anesthesia, General Anesthesia With ESP Block or TLIP Block in Patients Undergoing Lumbar Surgeries
The regional methods of anesthesia for the neurosurgical operations of the spine and spinal cord reducing the needs for opioids intra operatively and reducing pain in the postoperative period, decrease the numbers of failed back…
- Conditions
- Lumbar Disc Herniation, Lumbar Discogenic Pain, Lumbar Spinal Stenosis, Failed Back Surgery Syndrome
- Trial name
- NCT05447780
- Testing
- regional anesthesia
- Where
- Ukraine
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Anesthesia Research Group UA
Disc Herniation
Intradural Disc Herniation: a Case Report and Review of Complications
This observational study collects clinical data as well as pathological reports from a patient with an intradural disc herniation, reports on the course of the patient's recovery through surgical treatment, summarizes the…
- Trial name
- NCT06141551
- Testing
- total laminectomy decompression
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Gansu Provincial Hospital
Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes
Osaka Cardiometabolic Epidemiological Study: Ohtori Study Part 2
The aim of this study is to investigate the relationship between body fat distribution measured by CT scan and related risk factors with the risk of incident metabolic and cardiovascular disease in a prospective cohort study of…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes, Diabetes Mellitus, Hypertension
- Trial name
- OCES-2 (NCT06694012)
- Where
- Japan
- Volunteers
- 2,000 people
- Sponsor
- Osaka Metropolitan University
Bunion, Pain
Intravenous Tapentadol in Post-Bunionectomy Pain
The purpose of this trial is to established the safety and efficacy of multiple dose treatment with tapentadol IV in an adult population with moderate to severe pain following bunionectomy.
- Trial name
- NCT01435577
- Testing
- Tapentadol
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Grünenthal GmbH
Cardiac Implantable Electronic Device (CIED), Shoulder Dysfunction
Long-term Effects of Early Shoulder Exercise After CIED Implantation
Shoulder dysfunction frequently occurs after cardiac implantable electronic device (CIED) implantation, adversely affecting quality of life.
- Trial name
- NCT07496554
- Testing
- Structured Stretching and Strengthening Program, Standard Post-operative Care, Pendulum Exercise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Leukodystrophy, White Matter Disease
The Myelin Disorders Biorepository Project
The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects.
- Conditions
- Leukodystrophy, White Matter Disease, Leukoencephalopathies, 4H Syndrome
- Trial name
- MDBP (NCT03047369)
- Where
- 23 sites in United States
- Volunteers
- 12,000 people
- Sponsor
- Children's Hospital of Philadelphia
Cervical Cancer
Protecting Young Special Risk Females From Cervical Cancer Through Human Papilloma Virus (HPV) Vaccination
A research project is currently being undertaken looking at Human Papilloma Virus (HPV) vaccination in special risk groups. It aims to see if young women with a chronic illness respond well to the HPV vaccine or whether they may…
- Trial name
- HPV (NCT00964210)
- Testing
- Licensed quadrivalent HPV vaccine, Gardasil
- Where
- Australia
- Volunteers
- 240 people
- Sponsor
- Murdoch Childrens Research Institute
Spinal Fusion, Cervical Vertebral Fusion
Study of Titanium-Coated PEEK Cages for Degenerative Disc Disease
Prospective Follow-up study of CeSPACE XP coated PEEK cages for the treatment of degenerative cervical disc disease
- Trial name
- NCT03565224
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Aesculap AG
Urolithiasis and Aging, Renal Calcul and Metabolic Diseases
Metabolic Assessment of Aging Men With Urinary Lithiasis
Urinary lithiasis is a common disease on young adults, but not so far on aging people. Nowadays, the investigators are seeing a gradative growth on men above sixty years old, mainly in industrialized countries.
- Conditions
- Urolithiasis and Aging, Renal Calcul and Metabolic Diseases, Urolithiasis and Osteoporosis
- Trial name
- NCT01246531
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Systemic Lupus Erythematosus, Lupus Nephritis (LN)
An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases
This study evaluates the safety and efficacy of YTS109 cells in adults with relapsed/refractory autoimmune diseases, such as Systemic Lupus Erythematosus (SLE), including LN and SLE-ITP, Sjogren's Syndrome, etc.
- Conditions
- Systemic Lupus Erythematosus, Lupus Nephritis (LN), Sjogren's Syndrome, Inflammatory Myopathy
- Trial name
- NCT07236762
- Testing
- YTS109 cell
- Where
- China
- Volunteers
- 18 people
- Sponsor
- China Immunotech (Beijing) Biotechnology Co., Ltd.
Low Back Pain, Migraine
Evaluating the Safety and Tolerability of OraVescent Fentanyl for Opioid Tolerant Patients With Noncancer Related Breakthrough Pain
The purpose of this study is to evaluate the safety and tolerability of OraVescent fentanyl for the potential treatment of breakthrough pain episodes in patients who have chronic noncancer pain.
- Conditions
- Low Back Pain, Migraine, Diabetic Neuropathies, Osteoarthritis
- Trial name
- NCT00228605
- Testing
- OraVescent Fentanyl
- Where
- 38 sites in United States
- Volunteers
- 500 people
- Sponsor
- Cephalon
X Linked Hypophosphatemia
Burden of Disease and Functional Impairment in XLH
Observational study comprising prospective follow up as well as retrospective chart review in order to evaluate the longitudinal course of the disease in XLH patients with a specific focus on functional impairment, physical…
- Trial name
- IdeFIX (NCT04946409)
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Wuerzburg University Hospital
Rheumatic Disease, Neoplasms
Latest Imaging SPECT System Evaluation Phase 1
Monocentric study for the evaluation of a whole body CZT scintigraphy system.
- Conditions
- Rheumatic Disease, Neoplasms, Parathyroid Diseases, Pulmonary Embolism
- Trial name
- LISSE1 (NCT04704349)
- Testing
- Scintigraphy
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Charcot Arthropathy, Diabetes Complications
Zoledronic Acid or Methylprednisolone for Active Charcot's Neuroarthropathy of Foot in Patients With Diabetes Mellitus
Charcot neuropathic osteoarthropathy (CNO) is a progressively destructive process resulting from significant peripheral neuropathy of almost any aetiology. Diabetes mellitus has emerged as the commonest cause of CNO.
- Trial name
- NCT03289338
- Testing
- Zoledronic Acid, Methylprednisolone
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Wound Heal, Oral Dryness
Assessing the Efficacy of a Carbamide Peroxide Mouthwash for Oral Wound Healing, Oral Hygiene and Xerostomia Relief
The aim of this study is to evaluate the efficacy and safety of a carbamide peroxide mouthwash regarding oral wound healing, postoperative symptoms, xerostomia (dry mouth) and oral hygiene improvement.
- Conditions
- Wound Heal, Oral Dryness, Postoperative Pain, Sjogren's Syndrome
- Trial name
- NCT06363955
- Testing
- Carbamide Peroxide Mouthwash
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- National and Kapodistrian University of Athens
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