Clinical trials: Musculoskeletal Disease
Hepatitis C Patients
Immune Dysregulation in Hepatitis C Patients With or Without Arthritis
The purpose of this study is to study the role of the Immune System in causing arthritis in patients with Hepatitis C.
- Trial name
- NCT01195987
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Center for Rheumatic Disease, Allergy, & Immunology
Low Back Pain, Musculoskeletal Pain
Soft Active Back Exosuit to Reduce Workplace Back Pain
The goal of this clinical trial is to determine if a wearable back exosuit can make it safer and easier for workers who bend, lift, and lower objects in an industrial setting.
- Conditions
- Low Back Pain, Musculoskeletal Pain, Low Back Injury
- Trial name
- NCT05802914
- Testing
- Back Exosuit
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wyss Institute at Harvard University
Jaw, Edentulous
Prospective Observational Study of SynCone® Concept
The aim of this prospective observational study will be to evaluate patient-related outcomes, clinical, microbiological and peri-implant immunoinflammatory mediators in completely edentulous patients rehabilitated with delayed…
- Trial name
- NCT03957265
- Testing
- Tapered abutment connection
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marcio Zaffalon Casati
Trigger Point, Muscle Weakness
Effects of Deep Trigger Point Dry Needling on Strength Measurements of the Gluteus Medius Musculature
The purpose of this study will be to assess the effect that the application of deep trigger point dry needling to latent trigger points has on strength measurements.
- Trial name
- NCT03580200
- Testing
- Trigger Point Dry Needling
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emily Slaven, PT, PhD
Postural Balance
Evaluation of the Association Between Osteoporosis and Postural Balance in Postmenopausal Women
The incidence of osteoporosis has been increasing, as have fractures resulting from falls.
- Trial name
- NCT02771834
- Testing
- Biomechanical analysis, Kiphosis analysis, Vitamin D level
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Psoriasis, Synovitis
Comparison of the Frequency of Subclinic Synovitis in the Distal Interphalangeal Joints of the Hand in Psoriasis Patients
In this cross-sectional study, it was planned to compare the frequency of subclinical synovitis in the distal interphalangeal joints of the hands in psoriasis patients.
- Trial name
- NCT04750993
- Testing
- musculoskeletal ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Rheumatoid Arthritis, Psoriatic Arthritis
COVID-19 Infection in Vulnerable Patients With Inflammatory Rheumatic Diseases
The trial is a prospective, observational study aiming to identify risk factors for serious COVID-19 infection by evaluating clinical measures and biomarkers of inflammation in patients with inflammatory rheumatic disease…
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Axial Spondyloarthritis, Systemic Lupus Erythematosus
- Trial name
- NCT04335747
- Testing
- COVID-19 infection
- Where
- Denmark
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Salome Kristensen
Osteoarthritis, Knee
Cell-free Stem Cell-derived Extract Formulation for Knee Osteoarthritis
The purpose of this study is to determine the safety and efficacy of intraarticular injection of Cell-free Stem Cell-derived Extract Formulation for treatment of knee osteoarthritis symptoms.
- Trial name
- NCT04971798
- Testing
- Cell-free Stem Cell-derived Extract Formulation (CCM)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- General Therapeutics
Osteoporosis
The Nitrate and Bone Study: Effects of Nitrates on Osteoporosis
Osteoporosis or "thinning of the bones" affects in 1 in 4 Canadian women and 1 in 8 Canadian men. Moreover, while the rates of osteoporosis among Canadians are stabilizing, worldwide the number of people afflicted with…
- Trial name
- NCT00252421
- Testing
- Nitroglycerin ointment 15 mg/day daily for 24 month
- Where
- Canada
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes Mellitus, Osteoporosis
Type 1 Diabetes Mellitus Effect on Bone Mineral Density
Because the diabetics are fracturing at a younger age than the general population (12), this leads us to believe there are significant factors that lead to fracture in Type 1 diabetes mellitus (DM) other than bone mineral density…
- Trial name
- NCT01633684
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Creighton University
Obesity, Knee Osteoarthritis
BLOOM Forward: Investigating Weight Loss Impact on TJAC Patients
The goal of this clinical trial is to prospectively assess the efficacy of the BLOOM program, a comprehensive weight loss dietary and lifestyle program, in a population of patients living with obesity and awaiting hip or knee…
- Conditions
- Obesity, Knee Osteoarthritis, Hip Osteoarthritis, Arthroplasty Complications
- Trial name
- NCT06103552
- Testing
- Building Lifestyle Options for Orthopedic Mobility (BLOOM)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Osteoporosis, Post-Menopausal
Combination Osteogenic Therapy in Established Osteoporosis
This study is designed to determine if combining parathyroid (PTH 1-34) with fluoride (MFPSR) therapy in a cyclic treatment regimen will: (1) produce a greater increase in bone density of the spine than would be produced by…
- Trial name
- NCT00018447
- Testing
- PTH 1-34, MFPSR-fluoride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Aortic Stenosis
Loss of Y Chromosome in Aortic Stenosis
The most common heart valve disease in humans is aortic stenosis which is a critical narrowing of the valve through which the heart has to pump blood to the rest of the body.
- Trial name
- NCT06595407
- Testing
- Blood analysis for loss-of-Y chromosome
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Alveolar Bone Loss
Accuracy Assessment of Chin Graft for Ridge Augmentation Using Tooth-supported Guide Versus Free Hand Technique
This study compares the accuracy of osteotomies positions using patient specific guides for onlay bone shells harvested from the chin then the graft positioning for 3D upper anterior ridge augmentation using patient-specific…
- Trial name
- NCT07365852
- Testing
- 3D ridge augmentation using tooth-supported patient-specific guide
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low Back Pain
The Efficacy of A Smartphone Application in Treating Non-Specific Low Back Pain
Evaluating the efficacy of a newly developed self-monitored mobile application in reducing office workers low back pain.
- Trial name
- NCT03994458
- Testing
- Smartphone Full version application, Samartphone limited version application
- Where
- Jordan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Hemophilia A, Hemophilia B
Pre-clinical Models for Mesenchymal Stem Cell Therapy in Hemophilic Arthropathy
Hemophilia is a constitutional coagulation disorder responsible for a hemorrhagic phenotype in patients from an early age. Hemarthrosis is one of the most frequent complications in hemophiliacs and leads to the development of…
- Conditions
- Hemophilia A, Hemophilia B, Arthropathy
- Trial name
- NCT05187936
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Jaw, Edentulous, Partially, Dental Implants, Single-tooth
Long-term Effectiveness of Contour Augmentation in Sites With Early Implant Placement
In this prospective case series study, 20 patients with an implant-borne single crown following early implant placement with simultaneous contour augmentation will be followed for 10 years.
- Conditions
- Jaw, Edentulous, Partially, Dental Implants, Single-tooth, Grafting Bone
- Trial name
- NCT03252106
- Testing
- Contour augmentation with implant placement
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bern
Sjögren's Syndrome
Modulation of Immunity-related Gene Expression Under the Chinese Herbal Formula SS-1 Treatment for Sjögren's Syndrome
To evaluate the modulation of immunity-related gene expression for the Sjögren's syndrome under Chinese herbal medicine (SS-1) treatment.
- Trial name
- NCT02855658
- Testing
- SS-1
- Where
- 2 sites in Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Distal Radius Fractures, Wrist Fracture
Unstable Distal Radius Fractures With Dorsal Dislocation in Patients Aged 18-64 Years. Volar Locking Plate (VLP) vs Closed Reduction and Percutaenous Pinning (CRPP).
120 patients age 18-64 years with dorsally displaced distal radius fractures AO-type A2, A3 and C1 are recruited from Oslo Casualty Medical Centre (Oslo Skadelegevakt).
- Conditions
- Distal Radius Fractures, Wrist Fracture, Colles' Fracture
- Trial name
- NCT04716309
- Testing
- Open reduction and volar locking plate and closed reduction and K-wires.
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Osteoarthritis of the Hip
Total Hip Arthroplasty (THA) Surgical Techniques Comparing the Direct Anterior Approach to the Posterior Approach
The purpose of this study is to compare the short term effectiveness and return to function of subjects undergoing primary Total Hip Arthroplasty using an Anterior Approach (incision on the front part of the hip joint) versus…
- Trial name
- NCT01807104
- Testing
- Anterior Approach / Posterior Approach, Anterior versus Posterior Approach for total hip replacement
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Barrett, William, M.D.
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