Clinical trials: Musculoskeletal Diseases or Conditions
Neurological Conditions, Musculoskeletal Diseases or Conditions
IAMABLE: Implementation and Evaluation of an App for Evidence-Based Self-Management Rehabilitation Strategies
Background: As the population gets older, a rise in chronic conditions has resulted in increased demand for rehabilitation. We developed a web-based app called IAMABLE (I am able), to share evidence-based rehabilitation…
- Conditions
- Neurological Conditions, Musculoskeletal Diseases or Conditions, Cardiovascular Diseases
- Trial name
- IAMABLE (NCT06773169)
- Testing
- IAMABLE web-based app, General health information
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Tendinopathy, Musculoskeletal Diseases or Conditions
Human Tendon Tissue Collection
The goal of this study is to improve understanding of tendon health and disease by using surplus tendon tissue that is routinely removed during planned orthopaedic surgeries in adults.
- Conditions
- Tendinopathy, Musculoskeletal Diseases or Conditions, ACL Surgery, Achilles Tendon Surgery
- Trial name
- NCT07606092
- Where
- 2 sites in United Kingdom
- Volunteers
- 400 people
- Sponsor
- Queen Mary University of London
Hand Injuries and Disorders, Neurological Conditions
3D Hand Orthosis Trial
In people with chronic hand conditions, hand orthoses are frequently prescribed to improve performance in activities of daily living (ADL).
- Conditions
- Hand Injuries and Disorders, Neurological Conditions, Neuromuscular Diseases (NMD), Musculoskeletal Conditions (e.g., Tendinitis, Capsulitis)
- Trial name
- NCT07633821
- Testing
- 3D-printed hand orthosis (intervention), Conventional hand orthosis (control)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Musculoskeletal Diseases or Conditions
Orthobiological Therapies in Musculoskeletal Disorders
To evaluate the clinical and functional effects of using orthobiological therapies (hyaluronic acid, platelet-rich plasma, bone marrow aspirate, nanofat, among others) in the treatment of various musculoskeletal diseases in…
- Trial name
- PROREGEN (NCT07434115)
- Testing
- PRP injection, Bone Marrow Concentrate (BMAC), Hyaluronic Acid (Viscosupplementation)
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- PROREGEN
Musculoskeletal Disorders (MSDs), Musculoskeletal Diseases or Conditions
Exercise and Health Education for Textile Workers: A Pre-Post Study
Musculoskeletal disorders (MSDs) significantly impact quality of life, health status, and work ability. Standard treatments include ergonomic interventions, therapeutic exercise programs, education on risk prevention, active…
- Trial name
- LACOR-HEALTH (NCT07360626)
- Testing
- Combined Exercise Training and Health Education Program
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Hemophilia, Child, Only
Trial of an Exercise Intervention for Children With Haemophilia
"Being able to participate in games and activities with their friends" is one of the things that matters most to boys with haemophilia.
- Conditions
- Hemophilia, Child, Only, Musculoskeletal Diseases or Conditions
- Trial name
- DOLPHIN-II (NCT05895032)
- Testing
- Exercise, Usual Care
- Where
- United Kingdom
- Volunteers
- 132 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Musculoskeletal Diseases or Conditions
Short- and Medium-term Outcomes of the 3- Versus 4-week PV RehaJET® Rehabilitation Programme
The objective of this observational study is to evaluate and compare the outcomes of two different durations of a recently established work-specific rehabilitation programme in Austria.
- Trial name
- NCT07700017
- Testing
- Multimodal rehabilitation with additional work specific training
- Where
- Austria
- Volunteers
- 499 people
- Sponsor
- Pensionsversicherungsanstalt
Musculoskeletal Diseases or Conditions
Changes in Workability and Employment Following the Work-related Medical Rehabilitation PV RehaJET®
The objective of this observational study is to gain insight into a new approach to rehabilitation in Austria, with a particular focus on work-specific exercises that are dependent on the specific work-related needs of the…
- Trial name
- NCT06594120
- Testing
- Multimodal rehabilitation with additional work specific training
- Where
- Austria
- Volunteers
- 300 people
- Sponsor
- Pensionsversicherungsanstalt
Any Chronic, Non-traumatic Orthopedic Condition
Testing an AI Large Language Model Tool for Cognitive Debiasing in Musculoskeletal Care
The goal of this clinical trial is to find out whether using an artificial intelligence (AI) tool called a Large Language Model (LLM) can help patients think more clearly about their symptoms and improve their trust and…
- Trial name
- NCT07022769
- Testing
- LLM-facilitated cognitive debiasing aid
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Texas at Austin
Chronic Conditions, Multiple, Diseases of the Circulatory System
National Institute for Health and Care Research Global Health Research Centre for Multiple Long-Term Conditions
Multiple Long-Term Conditions (MLTC), defined as the coexistence of two or more chronic conditions, is increasingly prevalent in India.
- Conditions
- Chronic Conditions, Multiple, Diseases of the Circulatory System, Diseases of the Respiratory System, Endocrine, Nutritional and Metabolic Diseases
- Trial name
- NIHR-GHRC MLTC (NCT07582380)
- Testing
- Electronic Decision Support System (EDSS), Assisted Telemedicine, Patient-facing app for self-management, supported by care coordination through Community Champions and Care Coordinators.
- Where
- 120 sites in India, Nepal
- Volunteers
- 3,600 people
- Sponsor
- Centre for Chronic Disease Control, India
Achilles Tendinopathy (AT), Musculoskeletal Diseases or Conditions
STICK2IT - Understanding Why People Do or Do Not Stick With Exercise Treatment for Achilles Tendinopathy
Achilles tendinopathy is a common condition that causes pain and stiffness in the tendon at the back of the ankle. It can make walking, exercise, work, and everyday activities difficult.
- Conditions
- Achilles Tendinopathy (AT), Musculoskeletal Diseases or Conditions, Adherence, Behaviour Change
- Trial name
- NCT07555184
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Musculoskeletal Diseases or Conditions, Traffic Accident
Safety and Efficacy of Integrative Korean Medicine Treatment for Elderly After Traffic Accident
The purpose of this study was to analyze the medical records of elderly traffic accident patients hospitalized at 4 branches of Jaseng Korean Medicine Hospital to determine the status of elderly patients and the effectiveness and…
- Conditions
- Musculoskeletal Diseases or Conditions, Traffic Accident, Elderly (People Aged 65 or More)
- Trial name
- NCT07007299
- Where
- 4 sites in South Korea
- Volunteers
- 1,788 people
- Sponsor
- Jaseng Medical Foundation
Musculoskeletal Diseases or Conditions
Ergonomic Benefits From Robotically Assisted Laparoscopy for Hysterectomies and Other Indications
This is a prospective, single-center, observational clinical trial at the Department of Women's Health of the University Hospital Tübingen.
- Trial name
- ERCON (NCT06109753)
- Testing
- Robotically Assisted Laparoscopic Surgery, Conventional Laparoscopic Surgery
- Where
- Germany
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Rheumatoid Arthritis, Rheumatic Diseases
Prevalence of Musculoskeletal Complaints in Nursing Home Residents
The goal of this observational study is to investigate the prevalence of joint complaints in nursing home residents with and without dementia. Primary objective: Number of tender or swollen joints. Secondary objectives: 1.
- Conditions
- Rheumatoid Arthritis, Rheumatic Diseases, Musculoskeletal Diseases, Musculoskeletal Diseases or Conditions
- Trial name
- NCT06235710
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Musculoskeletal Diseases or Conditions, Spine; Arthrosis
The Safety of Pharmacopuncture on Musculoskeletal Patients
The purpose of this study is to evaluate the safety of pharmacopuncture by observing any adverse events that may occur after pharmacopuncture treatment in with spinal joint disease hospitalized patients at 7 Korean medicine…
- Trial name
- NCT05318859
- Testing
- Pharmacopuncture
- Where
- 7 sites in South Korea
- Volunteers
- 1,000 people
- Sponsor
- Jaseng Medical Foundation
Chronic Pain, Pain, Chronic
Virtual Reality - A New Vision on Pain
The purpose of the project is to investigate if the use of virtual reality (VR) technology with pre-programmed proprietary software can provide better treatment for patients with long-term pain conditions.
- Conditions
- Chronic Pain, Pain, Chronic, Musculoskeletal Disorder, Musculoskeletal Pain
- Trial name
- VROP (NCT06045741)
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- Sykehuset i Vestfold HF
Chronic Pain, Musculoskeletal Diseases or Conditions
PiPT in ADSM With MSD
The study objective is to establish feasibility of implementing a psychologically informed rehabilitation strategy while concurrently assessing its' effectiveness in Active duty service members (ADSM) with musculoskeletal…
- Trial name
- NCT05132400
- Testing
- Psychological-informed Physical Therapy (PiPT) Training
- Where
- United States
- Volunteers
- 427 people
- Sponsor
- NYU Langone Health
Musculoskeletal Diseases or Conditions
Prospective RCT Lidocaine & Levobupivacaine on Block Dynamics After Subparaneural Popliteal Sciatic Nerve Block
Sciatic nerve block at the popliteal fossa is indicated for foot or ankle surgery, and the introduction of ultrasound guidance (USG) has improved the ease and accuracy of the performance of this block.
- Trial name
- NCT04397484
- Testing
- 0.5% Levobupivacaine, 2% Xylocaine with adrenaline 1:200,000
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Musculoskeletal Diseases or Conditions
Minimum Effective Local Anesthetic Volume for Ultrasound Guided Superior Trunk Block
The objective of this study is to identify the minimum effective dosage of a commonly used local anaesthetic drug "levobupivacaine" required to produce an effective ultrasound guided (USG) superior trunk block (STB) in at least…
- Trial name
- NCT04941664
- Testing
- 0.5% levobupivacaine
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- Chinese University of Hong Kong