Clinical trials: Musculoskeletal Disorders
Temporomandibular Disorder, Oxidative Stress
Evaluation of Oxidative Stress and Inflammation Markers in Temporomandibular Disorders
Background: The occurrence of many diseases has been associated with oxidative stress and disruption of antioxidant mechanisms. Temporomandibular Joint(TMJ) Disorders are also thought to develop with the onset of the destructive…
- Conditions
- Temporomandibular Disorder, Oxidative Stress, Inflammation
- Trial name
- NCT05985733
- Testing
- Biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Alveolar Bone Loss
Using Boned-Apatite Cement at the Time of Extraction for Ridge Preservation at These Sites
To assess efficiency of ridge preservation (in vertical and horizontal dimensions) after tooth extraction using Calcium Sulfate with hydroxyapatite(®Bond-apatite) compared to the use of bovine bone substitute (BioOss®) and to…
- Trial name
- NCT02440048
- Testing
- Bond Apatite synthetic bone substitute, BioOss bovine bone substitute
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Knee Osteoarthritis
Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain
The purpose of this study is to evaluate the usability of the ultrasound devices and common pain relief gel. The ability of the three treatment approaches to reduce pain, stiffness, and functionality as measured by NRS scale and…
- Trial name
- NCT05050448
- Testing
- Sustained Acoustic Device with 2.5% Diclofenac Patch, 1% Diclofenac Topical Gel
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ZetrOZ, Inc.
Atrophic Maxilla
Comparing Resin and Metallic Surgical Guides for Zygomatic Implants in Patients With Severe Upper Jaw Bone Loss
Oral rehabilitation with dental implants in patients with severely atrophic maxillae often presents significant surgical challenges.
- Trial name
- NCT07912658
- Testing
- resin guide group, metal guide group
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoporosis, Obesity
Soy, Bone and Health in College Females
This is a 16-week intervention to determine the efficacy of an isoflavone-rich soy based meal supplement to improve bone health and prevent weight and fat gain in 18-19 year old college females.
- Trial name
- NCT00244478
- Testing
- Soy Protein Dietary Supplement
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Flat Foot
Therapeutic Effects of Customized Insoles on Children With Flat Foot
Using double blind, randomized controlled design to study the short-term therapeutic effects of customized arch-support shoe insoles to children with flat foot.
- Trial name
- NCT02414087
- Testing
- ICB Medical insoles
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Microcephaly
Guangzhou Surveillance and Clinical Study in Microcephaly (GSCSM)
Screening for microcephaly is important at birth and during early childhood. The Guangzhou Surveillance and Clinical Study in Microcephaly (GSCSM) aims to establish a multicentric surveillance system for microcephaly in newborns…
- Trial name
- NCT03651687
- Where
- China
- Volunteers
- 47,369 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Foot Diseases
The Effectiveness of a Protocol for Muscular Foot Strengthening On a Capacity to Control the Deformation of the DOT Plantar Medial
The human foot allows to perform several functions, rather than providing a Static support for the body, the foot acts dynamically in walking and Movement of the body, requiring adequate biomechanics responsible for Maintenance…
- Trial name
- NCT03117244
- Testing
- Exercise for Foot Strengthening, Exercise for Foot Strengthening and Electrostimulation
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Femoro Acetabular Impingement
Biomechanical Assessment of Femoroacetabular Impingement
The purpose of this study is to determine the influence of FAI abnormalities on hip joint biomechanics.
- Trial name
- FAI (NCT01575964)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Utah
Osteoporosis
A Study of Prevention and Treatment of Postmenopausal Osteoporosis in Chinese Women
The purpose of this trial is to study the efficacy and safety of low dose of estradiol valerate in the prevention and treatment of postmenopausal osteoporosis.
- Trial name
- NCT00860964
- Testing
- estradiol valerate
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Temporomandibular Joint Disorders
Temporary Hydrostatic Splint Therapy and Its Effects on Occlusal Forces
The goal of this non-randomized controlled trial is to analyze and compare occlusal force distribution patterns using T-Scan III before and after hydrostatic splint therapy on both healthy subjects and subjects with…
- Trial name
- NCT05827263
- Testing
- T-Scan occlusal recording No. I, Usage of the hydrostatic appliance, T-Scan occlusal recording No. II
- Where
- Lithuania
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Adhesive Capsulitis of the Shoulder
Arthroscopy and Manipulation vs a Home Therapy Program in the Treatment of Adhesive Capsulitis
The purpose of this study is to compare two treatments used for treating frozen shoulder which are arthroscopy and forceful stretching of the shoulder and home stretching therapy to see if one relives pain and improves shoulder…
- Trial name
- NCT00160784
- Testing
- Arthroscopy, Arthroscopic manipulation, Home therapy
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alveolar Bone Loss
Pontic Site Development Using Soft Tissue Augmentation
in patients with vertical or horizontal defective of there ridge it is difficult to have prosthetic restoration with natural appearance emetating and simulating the adjacent abutment emergence profile so this study aims to…
- Trial name
- NCT03834649
- Testing
- partially de-epithelized connective tissue graft, Mucograft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nouran Abdulla Mater,MD
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Scoliosis, Scoliosis; Adolescence
Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question[s]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS)…
- Conditions
- Scoliosis, Scoliosis; Adolescence, Scoliosis Kyphosis, Scoliosis Lumbar Region
- Trial name
- PKSforPSP (NCT06554093)
- Testing
- Medical Device - PKS
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Deep Health Ltd.
Plantar Fasciitis
Plantar Heel Pain: Multisegment Foot Motion and Muscle Function, FFI Translation, and Evaluation of Treatments
Plantar fasciitis (PF) is a prevalent musculoskeletal condition of plantar heel pain (PHP) that leads to pain, functional limitations, and reduced quality of life, especially among active adults aged 25 to 65.
- Trial name
- NCT03161314
- Testing
- Strengthening exercises, Stretching exercises
- Where
- 2 sites in Thailand
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Gout
Lesinurad/Allopurinol 200/300 Fixed-Dose Combination (FDC) Tablets Bioequivalence.
To assess the bioequivalence between lesinurad/allopurinol 200/300 FDC tablets and coadministered lesinurad and allopurinol tablets in the fasted state based on the pharmacokinetic (PK) evaluation of lesinurad and allopurinol in…
- Trial name
- NCT03272425
- Testing
- lesinurad/allopurinol 200/300 FDC tablets, lesinurad 200 mg, allopurinol 300 mg
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ardea Biosciences, Inc.
Muscle Recovery, Muscle Soreness
Accelerating Post-exercise Muscle Glycogen Resynthesis in Humans: Impact of Combined Nutrient Intake and Intermittent Pneumatic Compression or Heat Therapy
To determine if modalities designed to improve blood flow combined with post-exercise nutrient intake will improve replenishment of muscle glycogen better than nutrient intake alone.
- Conditions
- Muscle Recovery, Muscle Soreness, Glycogen Depletion
- Trial name
- NCT04371237
- Testing
- Compression sleeve, Heat therapy, Glycogen-depleting exercise session
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Osteoarthritis
Patient Controlled Epidural Analgesia Versus Local Infiltration Analgesia Following Knee Arthroplasty
The purpose of this study was to determine if the method of peri-operative analgesia used following total Knee Replacement surgery affected the progress towards rehabilitation goals and to determine whether the analgesia had any…
- Trial name
- NCT02478372
- Testing
- Patient Controlled Epidural (PCEA), Local Infiltration Analgesia (LIA)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Golden Jubilee National Hospital
Biomechanical Phenomena
Kinematics and Muscle Performance of the Trunk and Shoulder in Volleyball Players With Subacromial Impingement Syndrome
Volleyball players repetitively place the arm into extreme positions, and thus expose the athletes' shoulders to a large load and increase the risk of injuries.
- Trial name
- NCT05439122
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yi-Fen Shih
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