Clinical trials: Musculoskeletal Injuries
Bone Marrow, Femoral Neck Fractures
Bone Marrow Injection in Fracture of Femoral Neck
Objectives: Primary objective : To investigate the predisposing factors for femoral neck fractures, including age, sex, and associated comorbidities.
- Trial name
- NCT07808294
- Testing
- Anatomical reduction and fixation with bone marrow injection, Anatomical reduction with Fixation
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Yaser Alkanash
Incomplete Spinal Cord Injury, Muscular Dystrophy
Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders
Background: Cerebral palsy (CP) is the most common motor disorder in children. CP often causes crouch gait, an abnormal way of walking. Knee crouch has many causes, so no single device or approach works best for everybody.
- Conditions
- Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
- Trial name
- NCT01961557
- Testing
- EA-KAFO
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Tennis Elbow
Tissue Flossing in Tennis Elbow Patients
The aim of the present intervention is to determine the effectiveness of the application of tissue flossing in patients with tennis elbow
- Trial name
- FLOSS (NCT03834077)
- Testing
- Tissue flossing
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Jaén
Medial Tibial Stress Syndrome
Effect of Shortwave Diathermy and Therapeutic Ultrasound on Medial Tibial Stress Syndrome Among Military Cadets
Medial tibial stress syndrome (MTSS) also known as shin splints or tibial periostitis is a common injury in athletes and soldiers/cadets with incidences ranging between 4% and 35% in these populations .
- Trial name
- NCT04292795
- Testing
- Therapeutic Ultrasound, Short wave diathermy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Shifa Clinical Research Center
Shoulder Dislocation
Spaso Versus Self-assisted Maneuver for Anterior Shoulder Dislocation
To compare the results and efficacy of the self-assisted Boss-Holzach-Matter maneuver for anterior shoulder dislocation and the Spaso method performed by a physician.
- Trial name
- NCT02527603
- Testing
- Boss-Holzach-Matter method, Spaso method, Anti-Inflammatory Agents, Non-Steroidal
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Ankle and Hindfoot Arthrodesis
Long-term Safety and Effectiveness of AUGMENT® Injectable Bone Graft Compared to Autologous Bone Graft
The objective of this long-term study is to evaluate the long-term effectiveness and safety of AUGMENT® Injectable Bone Graft vs. autologous bone graft.
- Trial name
- NCT03998137
- Testing
- AUGMENT® Injectable Bone Graft, Standard of Care
- Volunteers
- 94 people
- Sponsor
- BioMimetic Therapeutics
Pain, Persistent Pain
Is Low-load Resistance Training With Blood Flow Restriction More Effective Than Traditional Rehabilitation of Military Personnel With Lower Limb Injuries
Pain can be one of the primary limiting factors to progress following musculoskeletal injury and may be caused by trauma or degenerative changes.
- Conditions
- Pain, Persistent Pain, Musculoskeletal Pain
- Trial name
- LIMITLESS (NCT06621953)
- Testing
- BFR, control group
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Stroke, Brain Injuries
The Efficacy of Dynamic Hand Splint Treatment in Spastic Hemiparetic Patients
The purpose of this randomized controlled trial was designed to study the efficacy of dynamic hand splinting on spastic hemiparetic patients due to stroke or traumatic brain injury.
- Trial name
- NCT04441437
- Testing
- Task-oriented training with a dynamic hand splint, Task-oriented training without a dynamic hand splint
- Volunteers
- 35 people
- Sponsor
- Chang Gung Memorial Hospital
Elbow Tendinopathy
The Analysis of Efficacy Factors for Autologous Platelet-Rich Plasma Therapy in the Treatment of Elbow Tendinopathy
To identify key factors influencing the effectiveness of platelet-rich plasma (PRP) therapy in treating elbow tendinopathy, a common degenerative condition.
- Trial name
- NCT06815042
- Testing
- Autologous Platelet-Rich Plasma (PRP) Injection
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- CHA University
Lateral Elbow Pain, Lateral Epicondylitis
Illness Perception and Treatment Expectations in Lateral Elbow Pain
This cross-sectional, correlational study aims to determine the predictors of illness perception and treatment expectations in adults with chronic lateral elbow pain.
- Conditions
- Lateral Elbow Pain, Lateral Epicondylitis, Tennis Elbow, Chronic Musculoskeletal Pain
- Trial name
- LEP-IPTE (NCT07722845)
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Acibadem University
Musculoskeletal Disorders, Emergency Care
Effect and Cost of a Physiotherapy-led Care Model in Emergency Departments for Patients With Minor Musculoskeletal Injuries
Both in Denmark and internationally, emergency departments have been overwhelmed for several years by a growing number of patients, combined with a shortage of doctors and nurses.
- Conditions
- Musculoskeletal Disorders, Emergency Care, Physiotherapy
- Trial name
- NCT07137754
- Testing
- Advanced practice physiotherapy, Usual Care
- Where
- Denmark
- Volunteers
- 800 people
- Sponsor
- Aarhus University Hospital
Musculoskeletal Injury, Pediatrics
Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children
The TOP-MAP pilot trial has multiple goals. The first goal of this pilot clinical trial is to find out if it will be possible to carry out a study at multiple pediatric emergency department sites (Peds ED) comparing Non-Steroidal…
- Conditions
- Musculoskeletal Injury, Pediatrics, Sprain and Strain of Ankle, Sprain Knee
- Trial name
- TOP-MAP (NCT07145645)
- Testing
- Voltaren Topical Gel, Ibuprofen Oral Suspension 100 mg/5mL, ORA-Blend Oral Suspension
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Tendinopathy, Adrenal Insufficiency
Evaluation of Efficacy and Hypothalamus-pituitary-adrenal Axis Suppression Due to Corticosteroids Intrabursal Injection
The purpose of this study is to compare the efficacy and effects on the hypothalamus-pituitary-adrenal axis of a single intrabursal injection of two different types of corticosteroids (methylprednisolone and triamcinolone) in…
- Trial name
- TPESP2011-12 (NCT01652495)
- Testing
- methylprednisolone acetate, Triamcinolone Acetonide
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Istituto Ortopedico Rizzoli
Lateral Epicondylitis (Tennis Elbow)
Blood Flow Restriction Training Versus Mulligan Technique in Treatment of Lateral Epicondylitis
The purpose of this study is to evaluate the effectiveness of blood flow restriction training (BFRT) verses Mulligan's technique in improving pain, grip strength, and functional outcomes in patients with lateral epicondylitis…
- Trial name
- NCT07236554
- Testing
- blood flow restriction, Mulligan's with mobilization, Exercise
- Where
- Egypt
- Volunteers
- 177 people
- Sponsor
- Cairo University
Cancer, Hematologic Malignancies
Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
The purpose of this study is to determine if denosumab is non-inferior to zoledronic acid in the treatment of bone disease from multiple myeloma.
- Conditions
- Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology
- Trial name
- NCT01345019
- Testing
- Denosumab, Zoledronic acid, Denosumab (for the open-label treatment phase)
- Where
- 309 sites in United States, Australia and 27 more
- Volunteers
- 1,718 people
- Sponsor
- Amgen
Lateral Epicondylitis
Clinical and Ultrasonographic Results of Intratissue Percutaneous Electrolysis in Lateral Epicondylitis
Lateral epicondylitis (LE) is the most common cause of lateral elbow pain. Intratissue percutaneous electrolysis (EPI technique) is a novel minimally invasive approach which consists in the application of a galvanic current…
- Trial name
- NCT02085928
- Testing
- Intratissue percutaneous electrolysis, associated with eccentric exercise and stretching
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- CEU San Pablo University
Opioid Use, Shoulder Osteoarthritis
Opioid-Free Shoulder Arthroplasty
Purpose of Study: To identify and provide a safe, opioid-free treatment pathway for shoulder arthroplasty with a focus on perioperative pain control and postoperative symptoms from treatment
- Conditions
- Opioid Use, Shoulder Osteoarthritis, Avascular Necrosis, Rotator Cuff Tear
- Trial name
- NCT03540030
- Testing
- Gabapentin, Celecoxib, toradol
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Tendinopathy
Identification and Treatment of Early Tendinopathy in Elite Athletes
Tendon injuries represent a significant problem in elite athletes. The understanding of the pathophysiology of tendinopathy is very sparse, and especially the early events in tendinopathy are unknown.
- Trial name
- NCT03642392
- Testing
- Identification and treatment of early tendinopathy
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Biceps Tendon Disorder, Tendinosis
Restoring the Anatomic Tension Relationship of the Long Head of the Biceps During Tenodesis
The goal of this clinical trial is to determine the clinical impact of restoring the anatomic-tension relationship of the long head of the biceps (LHB) when performing a biceps tenotomy and tenodesis.
- Conditions
- Biceps Tendon Disorder, Tendinosis, Rotator Cuff Injuries
- Trial name
- NCT06571695
- Testing
- Anatomic Long Head of Biceps Tensioning Technique, Traditional Long Head of Biceps Tensioning Technique
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Loyola University
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
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