Clinical trials: Musculoskeletal Injuries
Skull Base Neoplasms, Cerebrospinal Fluid Leakage
Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery
The purpose of this study is to specifically evaluate the effectiveness of PuraGel, a RADA16 polypeptide hydrogel, in expediting post-operative healing and re-mucosalization of the nasoseptal flap harvest site during endoscopic…
- Conditions
- Skull Base Neoplasms, Cerebrospinal Fluid Leakage, Nasal; Hypertrophy, Mucous Membrane (Septum)
- Trial name
- NCT05898074
- Testing
- Non-Absorbable Packing (Silastic Splint), PuraGel (RADA16) Hydrogel
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Brain Injuries, Spasticity, Muscle
Focal Muscular Vibration in Patients with Severe Acquired Brain Injury
Severe acquired brain injury (sABI) is a group of disorders that cause long-term disability. Rehabilitation is essential to counteract bed immobilization, muscle failure, pain, and sensory deficits that can affect the clinical…
- Trial name
- NCT05464160
- Testing
- Focal Muscular Vibration using the EVM EVO medical device (Endomedica, Italy), Conventional Rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Necrotizing Fascitis, Necrotizing Soft Tissue Infection
The Management of Necrotizing Soft Tissue Infection Wounds With Cytal® Wound Matrix and MicroMatrix®
This is a prospective, pilot, parallel group, randomized controlled trial with 1:1 allocation. This will be a single center study coordinated at the Cleveland Clinic Foundation (CCF) Main Campus in Cleveland, Ohio.
- Trial name
- NCT06857708
- Testing
- Cytal® Wound Matrix, MicroMatrix®
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Benjamin T. Miller
Diastasis of Muscle, Other Site
Abdominal Diastasis Repair by Robotic Surgery
The objective of the study is to evaluate the feasibility of a robot-assisted minimally invasive surgical technique for the management of diastasis of the rectus abdominis.
- Trial name
- PROMA1 (NCT04176874)
- Testing
- Robotic-assisted diastasis of the rectus abdominis muscles repair
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Plantar Fasciitis, Myofascial Trigger Point Pain
Myofascial Points Treatment With Focused Extracorporeal Shock Waves (ESW)
Plantar fasciitis (PF) is a common cause of heel pain. Among the several conservative treatment options, Extracorporeal Shock Wave Therapy (ESWT) is considered the standard treatment.
- Conditions
- Plantar Fasciitis, Myofascial Trigger Point Pain, Foot Injury
- Trial name
- ESW (NCT05090059)
- Testing
- Lower limb myofascial trigger points f-ESWT
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Padova
Spondylolisthesis
Posterior Lateral Fusion (PLF) With Dynesys
The primary purpose of this study is to track and document the clinical outcomes of patients with radicular pathology following posterior lateral fusion with the Dynesys Spinal System.
- Trial name
- NCT00791180
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Zimmer Biomet
Proximal Humeral Fracture, Dislocation
Proximal Humerus Fracture Dislocation Direction and Avascular Necrosis
The purpose of the study is to see if there is a connection between a proximal humerus fracture dislocation direction and the likelihood of developing avascular necrosis.
- Conditions
- Proximal Humeral Fracture, Dislocation, Dislocation Shoulder, Avascular Necrosis
- Trial name
- PHF-D (NCT05735561)
- Testing
- X-Ray
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Fraser Orthopaedic Research Society
Shoulder Impingement Syndrome
Effect of Exercise Programs on 3-dimensional Scapular Kinematics, Disability and Pain
The aim of this study is to investigate the effect of exercise program on 3-dimensional scapular kinematics, disability and pain on shoulder impingement with scapular dyskinesia.
- Trial name
- NCT02286310
- Testing
- Kinetic Chain Exercises, Traditional Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University
Acute Spinal Cord Injury.
Risedronate for the Prevention of Osteoporosis in People With Spinal Cord Injury.
The purpose of this study is to find out if Risedronate works to prevent osteoporosis after spinal cord injury.
- Trial name
- NCT00150696
- Testing
- Risedronate
- Where
- 2 sites in Canada
- Volunteers
- 38 people
- Sponsor
- Toronto Rehabilitation Institute
Shoulder Pain, Rotator Cuff Injury
Does The Type of Exercise Influence Outcome in Rotator Cuff Related Shoulder Pain
Rotator cuff related shoulder pain (RCRSP) is the most common shoulder disorder and its chronicization leads to multiple consequences such as early retirement, absenteeism from work, decreased participation and quality of life…
- Conditions
- Shoulder Pain, Rotator Cuff Injury, Rotator Cuff Tendinitis, Rotator Cuff Impingement Syndrome
- Trial name
- RCT-RCRSP (NCT03892603)
- Testing
- Strengthening exercises program, Motor control exercises program, Education and advice
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- Laval University
Musculoskeletal Injuries
Combined Effects of Calisthenics and Plyometric to Reduce Risk of Musculoskeletal Injuries Among School Going Children
The goal of this clinical trial is to know about the combined effects of calisthenics and plyometric exercises on reducing risk of MSK injuries among school-going children. The main questions it aims to answer are: 1.
- Trial name
- NCT06732687
- Testing
- Calisthenics, Plyometrics, Combined( Calisthenics+ Plyometrics)
- Where
- Pakistan
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Arthritis, Rheumatoid, Stress Disorder
Impact of Life Events and Psychological Stress in Rheumatoid Arthritis Set-up : Case-control Study Within a Multifactorial and Integrative Psychological Model
Rheumatoid Arthritis (RA) is an inflammatory rheumatic disease that can lead to structural damage and handicap. The RA physiopathology is multifactorial, including genetic and environmental risk factors.
- Trial name
- Stress-PR (NCT03550833)
- Testing
- Questionnaire, blood sample
- Where
- 5 sites in France
- Volunteers
- 152 people
- Sponsor
- University Hospital, Bordeaux
Osteoarthritis, Hip Dislocation
Supine Sleeping After Total Hip Replacement
Aim of the current study is to test the non-inferiority hypothesis of differences in early hip dislocation between a group of patients who will be restricted to sleep in supine position and a group without restricted sleeping…
- Trial name
- NCT02107248
- Testing
- Sleep position: no restrictions, Sleep position: supine
- Where
- Netherlands
- Volunteers
- 456 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Shoulder Impingement, Shoulder Pain
Study of the Effect of Neck Treatment on Shoulder Impingement
The purpose of this pilot study is to conduct research to determine the most effective physical therapy treatment for a condition called shoulder impingement.
- Conditions
- Shoulder Impingement, Shoulder Pain, Rotator Cuff Tendinitis, Cervical Degenerative Joint Disease
- Trial name
- NCT00764764
- Testing
- shoulder treatment, Shoulder AND cervical treatment
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- CAMC Health System
Spasticity, Muscle, Spinal Cord Injuries
Vibrotactile Coordinated Reset for Spasticity After Spinal Cord Injury
The purpose of our study is to evaluate vibrotactile Coordinated Reset (vCR) and its effects on spasticity symptoms in incomplete spinal cord injured patients. vCR will be administered with a device called the Stanford CR Glove.
- Trial name
- NCT06290609
- Testing
- Vibrotactile Coordinated Reset
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Osteoporosis, Management Care, Fracture
Optimization of Osteoporosis Management Among Patients Older Than 45 Years Old With Low Energy Fracture.
Harrington's metaphorical depiction captures the essence of the problem : "Osteoporosis care of fracture patients has been characterized as the Bermuda Triangle made up of orthopaedists, primary care physicians and osteoporosis…
- Trial name
- OPTIPOST (NCT02060747)
- Testing
- Coordinator-based post fracture program
- Where
- France
- Volunteers
- 480 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Myotoxicity
CPK Levels After LC and Association With Analgesic Modalities
Regional anesthesia and analgesia technics are widely and securely used during general surgery procedures. Interfascial plane blocks are the latest used ones for analgesia.
- Trial name
- NCT06508177
- Testing
- İnterfascial plane block, Standart analgesia plan
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun University
Subacromial Impingement Syndrome
The Effect of Phonophoresis in Subacromial Impingement Syndrome.
Subacromial impingement syndrome (SIS) is a dysfunction caused by an impingement of the rotator cuff tendon between the head of the humerus and the acromion as a result of changes in the subacromial space.
- Trial name
- NCT04676919
- Testing
- phonophoresis therapy with pulsed mode ultrasound, phonophoresis therapy with continuous mode ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Cukurova University
Lateral Epicondylitis
Effects of Mills Manipulation and Nirschel Exercises in Patients With Lateral Epicondylitis
To find effects of mills manipulation versus NIRSCHL EXERCISES on pain ,strength and function in patients with lateral epicondylitis.
- Trial name
- NCT05413967
- Testing
- Mills manipulation in addition to myofasical release therapy, Nirschl exercises in addition to myofascial release therapy
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Tendinopathy, Achilles Tendon Injury
Autologous Tenocyte Implantation in Patients With Chronic Achilles Tendinopathy
This study is designed to compare the treatment of 2 groups in patients with Achilles tendinopathy: autologous tenocytes injection in combination with exercises versus saline injection in combination with exercises
- Conditions
- Tendinopathy, Achilles Tendon Injury, Achillodynia
- Trial name
- ATI (NCT01343836)
- Testing
- Autologous Tenocyte Implantation, Saline
- Where
- Netherlands
- Volunteers
- 90 people
- Sponsor
- Erasmus Medical Center
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