Clinical trials: Musculoskeletal Injuries
Hip Osteoarthritis, Leg Length Discrepancy
An Intelligent Instrument for Improved Leg Length and Hip Offset Accuracy in Total Hip Arthroplasty
Leg length discrepancies following total hip arthroplasty have been associated with nerve palsies, gait abnormalities, and lower back pain.
- Conditions
- Hip Osteoarthritis, Leg Length Discrepancy, Dislocation
- Trial name
- NCT02095093
- Testing
- Intellijoint HIP, Outrigger
- Where
- Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Tennis Elbow
Comparative Study Between Different Mobilization Techniques for Patients With Chronic Tennis Elbow
Background: Tennis elbow is a common musculoskeletal disorder affecting the functional activities of daily living through common extensor tendinopathy.
- Trial name
- RCT (NCT06812377)
- Testing
- Maitland joint mbilization, mulligan mobilization, radial nerve mobilization
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Tendinopathy
The Acute Effects of an Isometric Loading Intervention on Lower Extremity Landing Biomechanics in Individuals With Patellar Tendinopathy
The purpose of this study is to determine differences in lower extremity landing biomechanics and real-world physical activity between individuals with patellar tendinopathy compared to individuals without patellar…
- Trial name
- NCT03262181
- Testing
- Isometric Exercise
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Sport Injury
Predictors of Muscle Injury Risk in Non-professional Football Players
Background. Football accounts for 30% of all sports injuries. Muscle injuries in football are the most common non-traumatic and non-contact injuries.
- Trial name
- NCT06425809
- Testing
- Observation
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- University of Oviedo
Shoulder Impingement Syndrome, Kyphosis Thoracic
Maitland Thoracic Mobilization Versus Mulligan Thoracic Mobilization in Kyphotic Patients With Shoulder Impingement Syndrome
In recent years the management of shoulder impingement syndrome (SIS) included the thoracic spine as it was proved that it's highly correlated to pathologies in shoulder joint.
- Trial name
- NCT05605730
- Testing
- Maitland mobilization for thoracic spine, Mulligan thoracic sustained natural apophyseal glide (SNAGS), Traditional exercise management
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Injuries, Exercise
Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion
Osteoarthritis (OA) is a leading cause of disability worldwide that affects millions of Americans each year. Posttraumatic OA (PTOA) significantly impacts patients after anterior cruciate ligament (ACL) injury and ACL…
- Conditions
- Anterior Cruciate Ligament Injuries, Exercise, Cartilage, Articular, Knee Injuries
- Trial name
- NCT04906499
- Testing
- Physical Activity Promotion
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis of the Shoulder
TITAN™ Reverse Shoulder System
The Integra® TITAN™ Reverse Shoulder System (TRS) is a semi-constrained total shoulder construct. When used under the conditions and purposes intended the TRS will relieve pain and restore some functional joint motion to the…
- Trial name
- NCT02204228
- Testing
- TITAN™ Reverse Shoulder System (TRS)
- Where
- 10 sites in United States, France and 2 more
- Volunteers
- 151 people
- Sponsor
- Smith & Nephew, Inc.
Shoulder Dislocation
Hypnosis to Reduce Pain and Drugs for Shoulder Dislocation Management
The effectiveness of hypnosis for reducing pain was evaluated in various medical specialities. However, only few studies have demonstrated the efficacy of hypnosis for the management of pain in the emergency medicine.
- Trial name
- HYPSEM (NCT04992598)
- Testing
- Hypnosis session, Reduction
- Where
- 7 sites in France
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Treatment Outcome, Muscle Dystonia
Quantifying Muscle Tone in Patients With Brain Injury - a Feasibility Study
This project will determine the feasibility and validity of measuring elbow muscle flexor stiffness in a population of patients with sub-acute severe acquired brain injury using two measurement methods, the portable spasticity…
- Conditions
- Treatment Outcome, Muscle Dystonia, Spasticity, Muscle, Muscle Tightness
- Trial name
- NCT04207632
- Testing
- Botulinum toxin type A injection
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis, Arthritis, Rheumatoid
A Study of Rabeprazole for Prevention of Non Steroidal Anti-inflammatory Drug -Associated Gastroduodenal Injury
The aim of this study is to determine whether rabeprazole is superior to placebo in preventing dyspepsia and gastroduodenal injury in subjects with osteoarthritis (OA) and/or rheumatoid arthritis (RA) and/or bone pain.
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Dyspepsia
- Trial name
- NCT01140828
- Testing
- Rabeprazole
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Chinese University of Hong Kong
Cancers, Cardiovascular Diseases
Cohort of Swedish Men
The Cohort of Swedish Men began in 1997, when all men born between 1918 and 1952 and residing in two counties in central Sweden received a questionnaire including about 350 items concerning diet and other lifestyle factors.
- Conditions
- Cancers, Cardiovascular Diseases, Cataract, Gastrointestinal Diseases
- Trial name
- COSM (NCT01127711)
- Volunteers
- 48,850 people
- Sponsor
- Karolinska Institutet
Patellar Dislocation
Comparison of Two Graft Choices in Mediale Patellofemoral Ligament Reconstruction (MPFL)
The purpose of this study is to elucidate surgical techniques for reconstructing MPFL in the treatment of chronic patella instability.
- Trial name
- NCT05706363
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Shoulder Impingement Syndrome, Rotator Cuff Injuries
The Role of Pectoralis Minor Tightness in the Development of Rotator Cuff Tears
This study investigates whether tightness of a small chest muscle called the pectoralis minor is associated with the development of partial rotator cuff tears in the shoulder.
- Conditions
- Shoulder Impingement Syndrome, Rotator Cuff Injuries, Pectoralis Minor Tightness, Pectoralis Minor Muscle Tension
- Trial name
- PMinor-Rotator (NCT07228936)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gazi University
Hamstring Injury, Muscle Tone Increased
Cranial Laser Reflex Technique for Hamstring Function
Purpose: To conduct a pilot study of the effect of Cranial Laser Reflex Technique (CLRT) compared with sham laser on hamstring muscle flexibility, strength, and pain pressure threshold.
- Conditions
- Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
- Trial name
- CLRTHam (NCT03044106)
- Testing
- CLRT
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Intraoperative Musculoskeletal Injury
Intraoperative Laxity Assessment of ACL Reconstruction, ACL Revision and MAT
Intraoperative knee laxity evaluation of patiente undergoing ACL reconstruction, ACL revision, MAT
- Trial name
- INTRA_KIN (NCT03441165)
- Testing
- ligament reconstruction and meniscus transplantation
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Istituto Ortopedico Rizzoli
Femoral Neck Fractures, Osteoporosis
Complications and Functional Outcome of Displaced Femoral Neck Fractures in Patients Younger Than 70 Years
Patients younger than 70 years with a displaced femoral neck are in serious conditions. The femoral neck fracture is associated with low activity levels, hip pain and substantially reduced quality of life.
- Trial name
- NCT02085707
- Testing
- Total hip replacement arthroplasty, Closed reduction and internal fixation
- Where
- 4 sites in Norway
- Volunteers
- 118 people
- Sponsor
- University Hospital, Akershus
Osteoarthritis, Knee
Efficacy of Allogeneic UCMSCs for Treating Large Defects Knee Injury
In terms of the surgical treatment of the cartilage injury, various techniques and ways are created to repair or regenerate articular surface of synovial joint following traumatic damage or degeneration of the cartilage.
- Trial name
- NCT05016011
- Testing
- Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs), Marrow cellution
- Where
- Malaysia
- Volunteers
- 28 people
- Sponsor
- Cytopeutics Sdn. Bhd.
Total Knee Replacement
Biochemical Approach to Measuring Surgical Trauma
This study will examine the magnitude and time course of changes in circulating (serum and plasma) biomarker concentrations associated with musculoskeletal injury created by total knee replacement surgery.
- Trial name
- NCT01037400
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Traumatic Brain Injury
Pilot, Proof-of-Concept Study of Sublingual Tizanidine in Children With Chronic Traumatic Brain Injury (TBI)
Nightly administration of a unique, sublingual (under the tongue) formulation of tizanidine, a known anti-spasticity medication, has been shown in a previous study to improve sleep and next-day functioning in CP (cerebral palsy)…
- Trial name
- NCT00287157
- Testing
- Sublingual Tizanidine HCl
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Teva GTC
Orthopedic Trauma Surgery Patients, Postoperative Pain
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma.
- Conditions
- Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression
- Trial name
- NCT06903819
- Testing
- Ketamine, standard general anesthesia
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Texas Tech University Health Sciences Center
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