Clinical trials: Musculoskeletal Injuries
Spinal Cord Injuries, Upper Extremity Problem
Upper Extremity Pathologies in Spinal Cord Injuries
This study aims to determine the relationship between upper extremity pathologies and demographic data, duration of manual wheelchair use, duration of injury, physical examination and musculoskeletal ultrasound measurements in…
- Conditions
- Spinal Cord Injuries, Upper Extremity Problem, Musculoskeletal Pain
- Trial name
- NCT06278740
- Testing
- Musculoskeletal Ultrasound
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Afyonkarahisar Health Sciences University
Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC)
The KinematX Midcarpal Total Wrist Arthroplasty Registry
The goal of this observational study is to learn about functional and patient reported outcomes in patient undergoing total wrist replacement with the KinematX total wrist replacement study.
- Conditions
- Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC), Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC), Carpal Tunnel Syndrome (CTS)
- Trial name
- NCT05719935
- Testing
- KinematX total wrist arthroplasty system
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Extremity Medical
Lateral Epicondylitis
Conservative Treatment in Lateral Epicondylitis
Conservative treatments follow the vast majority of treatments in lateral epicondylitis. In this research, we aimed to elucidate the treatment outcomes of patients via epicondylitis bandage, wrist dorsiflexion splint, and kinesio…
- Trial name
- NCT06730789
- Testing
- Epicondylitis bandage, Wrist dorsiflexion splint, Kinesio tape
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Uludag University
Lateral Epicondylitis
Scapular PNF Versus Shoulder Strengthening Exercises in Patients With Lateral Epicondylitis.
The purpose of this study is to compare between the effect of scapular proprioceptive neuromuscular facilitation versus shoulder and scapular strengthening exercise on pain, functional outcome and grip strength in patients with…
- Trial name
- PNF (NCT05947968)
- Testing
- Scapular PNF, Shoulder strengthening exercises
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mahmoud Essam Abu Elfetouh Ghallab
Degenerative Joint Disease, Osteoarthritis
Comparison of Clinical Outcomes and Performance of Total Knee Replacement Patients Before and After Surgery
This study is to determine the relevancy of clinical scales for outcome measures as compared to flexion angle and other gait measures.
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Knee Injury, Trauma, Connective Tissue Disorder
- Trial name
- TKR (NCT01379118)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Tendinopathy
Mechanisms Behind Development of Tendinopathy
There has been an increasing amount of musculoskeletal injuries the past decades and overused tendons represents a major problem both for leisure and occupational activities.
- Trial name
- TESINaC (NCT02797925)
- Testing
- Training
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Subluxation
Patient Perceptions Following a Single Session of Simulated or Genuine HVLA Manual Chiropractic Adjustments
The primary aim of this trial is to assess blinding following simulated/sham or genuine/real high velocity, low amplitude (HVLA) manual chiropractic adjustments.
- Trial name
- SHA (NCT06153290)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Life University
Tendinopathy
Hyaluronan in the Treatment of Painful Tendinopathy
The primary objective of this study is to evaluate the efficacy and safety of TCHY106 (2% hyaluronan) in the treatment of painful tendinopathy.
- Trial name
- NCT01290510
- Testing
- hyaluronic acid sodium salt
- Where
- 2 sites in Germany
- Volunteers
- 35 people
- Sponsor
- TRB Chemedica AG
Long Bone Delayed-Union Fracture
Phase 1/2a Study on Allogeneic Osteoblastic Cells Implantation in Delayed-Union Fractures
Fracture healing is a complex physiological process caused by interaction of cellular elements, cytokines and signaling proteins, which results in the formation of new bone.
- Trial name
- NCT02020590
- Testing
- ALLOB® implantation
- Volunteers
- 25 people
- Sponsor
- Bone Therapeutics S.A
Raynaud Phenomenon Due to Trauma, Raynaud Disease
Topical 10 % Nifedipine Versus 5% Sildenafil in Secondary Raynaud
Objective: To compare the efficacy of topical 10% nifedipine versus 5% sildenafil in patients with secondary Raynaud's phenomenon (RP).
- Conditions
- Raynaud Phenomenon Due to Trauma, Raynaud Disease, System; Sclerosis, Lupus Erythematosus, Systemic
- Trial name
- NCT03027674
- Testing
- 10% nifedipine cream, 5% sildenafil cream
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Rotator Cuff Injuries, Rotator Cuff Tears
Tranexamic Acid to Improve Arthroscopic Visualization in Shoulder Surgery
The purpose of this study is to determine if intravenous TXA is a safe alternative to epinephrine in improving arthroscopic shoulder visualization. Primary Objectives 1.
- Conditions
- Rotator Cuff Injuries, Rotator Cuff Tears, Subacromial Impingement, Subacromial Impingement Syndrome
- Trial name
- NCT04594408
- Testing
- Epinephrine, Tranexamic acid, Epinephrine and Tranexamic Acid
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- Panam Clinic
Lateral Epicondylitis
Comparison of Two Combined Therapeutic Methods for Treatment of Lateral Epicondylitis
To compare the effectiveness of two combined therapeutic methods including corticosteroid injections with elbow cast versus ice massage and non-steroidal anti inflammatory drugs (NSAIDs).
- Trial name
- NCT00554476
- Testing
- Triamcinolone Acetonide- Indomethacin-Cryotherapy-Casting
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Azad University of Medical Sciences
Soft Tissue Injuries of the Shoulder, Tenosynovitis and Bursitis Affecting the Shoulder
Etoricoxib in Acute Soft Tissue Rheumatism Affecting the Shoulder
The purpose of this study is to evaluate the efficacy and safety two oral doses of etoricoxib (60 mg and 90 mg) daily in acute soft tissue rheumatism affecting the shoulder.
- Trial name
- NCT00876317
- Testing
- Etoricoxib 60 mg, Etoricoxib 90 mg
- Where
- Peru
- Volunteers
- 45 people
- Sponsor
- Clinica Virgen Milagrosa
Spinal Cord Injuries, Spine Disease
Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial)
This randomized clinical trial will compare three groups of individuals with cervical/thoracic, complete or incomplete spinal cord injury (SCI) that will undergo: (i) early CPAP therapy in the management of moderate-to-severe…
- Trial name
- NCT05473689
- Testing
- Continuous positive airway pressure (CPAP) therapy
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University Health Network, Toronto
Vitamin D Deficiency, Osteoporosis
Study to Document the Phenomenon of Vitamin D Deficiency and Its Added Value in Patients with Low-energy Osteoporotic Hip Fracture, in Daily Practice in Greece.
Vitamin D, through its action on calcium metabolism, is essential for bone physiology. Vitamin D deficiency can affect muscle function and increase the risk of falls in the elderly, while severe deficiency is common in patients…
- Conditions
- Vitamin D Deficiency, Osteoporosis, Bone Loss, Age-Related, Fracture of Hip
- Trial name
- NCT06643650
- Testing
- CHOLECALCIFEROL ORAL.SOL 25000 IU/2,5ML
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- National and Kapodistrian University of Athens
Lateral Epicondylitis
Recover L-PRP in Lateral Epicondylitis (REGP-11-00)
The objective of the study is to further characterize the performance of L-PRP prepared using the Biomet Recover Kit in the treatment of chronic LE.
- Trial name
- NCT02588040
- Testing
- Leukocyte- and Platelet-Rich Plasma (L-PRP)
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Zimmer Biomet
Osteoarthritis
Autologous Bone Marrow Mesenchymal Stem Cells Transplantation for Articular Cartilage Defects Repair
This is a non-randomized study aimed to determine the safety and efficacy of intra-articular injection of autologous bone marrow-derived mesenchymal stem cells in patients with knee articular cartilage defects.
- Trial name
- NCT01895413
- Testing
- Bone marrow aspiration
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Alexandra Cristina Senegaglia
Covid19, Trauma
Impact of COVID-19 Pandemic on Orthopaedic Practice
The COVERT Collaborative is led by a group of academic surgeons that is looking into the impact of the unprecedented COVID-19 pandemic on Trauma and Orthopaedic practice.
- Conditions
- Covid19, Trauma, Orthopedic Disorder, Anesthesia
- Trial name
- COVERT (NCT05026788)
- Testing
- type of treatment
- Where
- United Kingdom
- Volunteers
- 5,000 people
- Sponsor
- Imperial College Healthcare NHS Trust
Tennis Elbow, Epicondylitis, Lateral Humeral
Relationships Between Ultrasound Data and the Impact of Lateral Epicondylar Pain
Our primary objective is to study the relationship between ultra sound data and the pain associated with tennis elbow.
- Trial name
- EPICORE (NCT01390454)
- Testing
- Ultrasound of the elbow 1, days 7 to 15, Ultrasound of the elbow 2, days 7 to 15, Ultrasound of the elbow 3, days 45 to 90
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Inflammation, Spinal Cord Injuries
Anti-inflammatory Diet Consultation for Those With Neuromuscular Disability
This study investigated the effects of a 2-part dietary consultation on adherence to an anti-inflammatory diet in individuals with neuromuscular disability.
- Conditions
- Inflammation, Spinal Cord Injuries, Multiple Sclerosis, Muscular Dystrophies
- Trial name
- NCT05881122
- Testing
- Mad Dog Dietary Consultation
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Brock University