Clinical trials: Musculoskeletal Injuries
Hip Osteoarthritis
OXINIUM◊ DH Total Hip Arthroplasty Pivotal Study
The purpose of this study is to monitor safety of the participants implanted with the OXINIUM◊ DH Hip System up to 10-years post-implantation
- Trial name
- NCT02353377
- Testing
- OXINIUM DH Hip System, BIOLOX◊
- Volunteers
- 413 people
- Sponsor
- Smith & Nephew, Inc.
Work-related Injury, Burnout
The Effect of Exercise and Ergonomics Training Program on Musculoskeletal Disorders in Teachers
This randomized controlled trial tested whether adding a 12-week structured exercise program to ergonomics training improves low back and neck disability, burnout, musculoskeletal symptoms, and pain intensity in schoolteachers…
- Conditions
- Work-related Injury, Burnout, Neck Pain, Low Back Pain
- Trial name
- NCT07442383
- Testing
- ergonomics training, Structured exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Uskudar University
Osteoporosis
HIV UPBEAT: Understanding the Pathology of Bone Disease in HIV-infected Patients.
Despite the prevalence of osteopenia and osteoporosis in the HIV positive population, relatively little is known about the underlying pathology.
- Trial name
- UPBEAT (NCT01778361)
- Where
- Ireland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Acute Spinal Cord Injury, Spinal Cord Injuries
Spasticity and Functional Recovery After SCI
Spasticity is one of the most common symptoms manifested in humans with spinal cord injury (SCI). However, the neural mechanisms underlying the development of spasticity over time after an acute SCI are not yet understood.
- Trial name
- NCT06030531
- Testing
- Measures of spasticity, connectivity and analysis of single nucleotide polymorphisms and biomarkers of inflammation, Analysis of biomarkers
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Epicondylitis of the Elbow, Servical Segmental Mobilization
Results of Cervical Segmental Mobilization in Patients With Chronic Lateral Epicondylitis
The aim of our study was to investigate the effect of cervical segmental mobilization on pain, functionality, grip strength and quality of life in patients with chronic lateral epicondylitis.
- Trial name
- NCT06440928
- Testing
- mobilization, standard treatment, deep friction
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Halic University
Elbow Pain, Supracondylar Humerus Fracture
The Utilization of Ultrasound to Diagnose Pediatric Elbow Fractures
The goal of this intervention trial is to learn if a ultrasound diagnosis of elbow fractures can improve care in pediatric patients seen in the emergency room.
- Conditions
- Elbow Pain, Supracondylar Humerus Fracture, Radial Head Fractures, Radial Head or Neck Fractures
- Trial name
- NCT07212036
- Testing
- Ultrasound of the elbow, X-ray of elbow
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Defect of Articular Cartilage, Osteochondral Lesion of Talus
DeNovo NT Ankle LDC Study
The purpose of this post-market clinical study is to collect long-term outcomes for DeNovo NT Graft treatment of articular cartilage lesions in the ankle in a standard clinical setting.
- Conditions
- Defect of Articular Cartilage, Osteochondral Lesion of Talus, Osteochondritis Dissecans
- Trial name
- NCT01347892
- Testing
- DeNovo NT Natural Tissue Graft
- Where
- 8 sites in United States
- Volunteers
- 205 people
- Sponsor
- Zimmer Orthobiologics, Inc.
Tendinopathy
The Effect of High Volume Injection With and Without Steroid in Chronic Achilles Tendinopathy
The aim of the study is to determine the effect of steroid in High Volume Injection (HVI) compared to HVI without steroid (volume effect) in functional outcomes and ultrasound tendon thickness and Color Doppler activity in…
- Trial name
- NCT02839577
- Testing
- High Volume injection without corticosteroid, High Volume injection with corticosteroid
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Ankle Sprains, Instability, Joint
Urdu Version of Identification of Functional Ankle Instability Questionnaire
Functional instability should be considered as a potential cause of residual ankle impairment and instability. Even if neuromuscular anomalies are detected, the precise cause of injury and the most efficient prevention strategies…
- Trial name
- NCT06052657
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- University of Lahore
Bone Fractures, Bone Defects
Study on Safety and Performance of AdvanCore Bone Void Filler
The objective of this study is to evaluate the safety and performance of AdvanCore implantable bone graft through a 12-month follow-up period in a prospective, parallel-group design, non-controlled, open label, multi-center and…
- Conditions
- Bone Fractures, Bone Defects, Bone Loss, Bone Graft
- Trial name
- NCT06736457
- Testing
- AdvanCore bone grafting
- Where
- 4 sites in Portugal
- Volunteers
- 190 people
- Sponsor
- Artur Salgado SA
Skin Condition, Cleft Lip and Palate
Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study
A visible difference can have a profound impact in a society with a massive emphasis on appearance and "looks". A vulnerable group is adolescents with a condition affecting their appearance as a result of injuries (burns…
- Conditions
- Skin Condition, Cleft Lip and Palate, Burns, Other Conditions Leading to a Visible Difference
- Trial name
- UNGFaceIT (NCT03165331)
- Testing
- Ung Face IT
- Where
- Norway
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cleft Palate, Plasma Rich in Growth Factors
Role of Plasma Rich Growth Factor in Repair Primary Cleft Palate
Does the plasma-rich growth factor (PRGF) with primary cleft palate repair accelerate wound healing and prevent post-operative oronasal fistula occurrence?
- Trial name
- PRGF (NCT06889181)
- Testing
- Plasma Rich in Growth Factors (PRGF)
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Cleft, Distraction of Bone
Evaluation of the Efficiency of Bone Born Intra Oral Distractor for Closure of Wide Alveolar Cleft
The study aimed to determine efficiency of Bone-Born Intraoral Distractor on wide Alveolar cleft patients
- Trial name
- BBID-WAC (NCT07306429)
- Testing
- Bone-borne Intra oral distractor
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Faculty of Dental Medicine for Girls
Tetraplegia, Tetraplegia/Tetraparesis
[BrainConnexion] - Neurodevice Phase I Trial
This study aims to evaluate the safety of a wireless implantable neurodevice microsystem in tetraplegic patients, as well as the efficacy of the electrodes for long-term recording of neural activities and the successful control…
- Conditions
- Tetraplegia, Tetraplegia/Tetraparesis, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
- Trial name
- NCT03811301
- Testing
- BrainConnexion
- Where
- Singapore
- Volunteers
- 5 people
- Sponsor
- National Neuroscience Institute
Muscle Atrophy, ACL Reconstruction
Testosterone Administration and ACL Reconstruction in Men
This study is being done to test whether taking testosterone can prevent loss of muscle mass and strength due to anterior cruciate ligament (ACL) reconstructive surgery.
- Conditions
- Muscle Atrophy, ACL Reconstruction, Trauma, Osteoarthritis
- Trial name
- TACL (NCT01595581)
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Southern California
Ankle Sprains, Instability, Joint
Evaluation of Proprioception in Patients Treated With Surgical External Ankle Ligament Recontruction for Traumatic Ankle Instability
The objective of the study is to evaluate post-operatively the postural control through the Delos system with the Riva method of patients already treated surgically of external capsulo-ligament reconstruction due to ankle…
- Trial name
- ANKLE-PRO (NCT05868681)
- Testing
- Delos instrument (computerized balance board)
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- Istituto Ortopedico Rizzoli
Knee Arthritis, Osteoarthritis, Osteo Arthritis of the Knee
Quadriceps Muscle Quality and Clinical Outcomes in Knee Osteoarthritis
The purpose of this cross-sectional, observational study is to evaluate the relationship between quadriceps muscle quality-specifically muscle echogenicity and thickness change during isometric contraction-and clinical outcomes…
- Trial name
- NCT07541274
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital
Child, Cerebral Palsy
Prevention of Hip Displacement in Children With Cerebral Palsy in Denmark
Children with cerebral palsy have an increased risk of hip dislocation, which is a painful and severe complication of cerebral palsy.
- Conditions
- Child, Cerebral Palsy, Radiography, Hip Dislocation
- Trial name
- NCT04403178
- Testing
- Radiographic examination with a Migration of > 40 %
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Mette Røn Kristensen
Shoulder Pain, Frozen Shoulder
Simple and Evidence-based Examination and Treatment of Shoulder Pain in General Practice
Previous research suggests that general practitioners find handling patients with shoulder pain difficult and that the current care for shoulder pain is not in line with the best available evidence (1).This project aims to assess…
- Conditions
- Shoulder Pain, Frozen Shoulder, Rotator Cuff Tendinosis, Myalgia
- Trial name
- EASIER (NCT04806191)
- Testing
- Evidence based treatment strategy, Targeted patient information package, Treatment as usual (TAU)
- Where
- 2 sites in Norway
- Volunteers
- 160 people
- Sponsor
- University of Oslo
Hyperthermia, Chronic Primary Pain
Hyperthermia in Patients With Chronic Primary Pain - Effects on Thermoregulation, Somatosensory System and Movement Evoked Pain
This study, in a quasi-experimental matched two-group pre-post design, investigates the effect of serial water-filtered whole-body hyperthermia on circadian core body temperature, the somatosensory system (nociception) and the…
- Conditions
- Hyperthermia, Chronic Primary Pain, Widespread Pain, Muscular Disease
- Trial name
- HYPPRI-1 (NCT07101978)
- Testing
- serial whole body hyperthermia
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
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