Clinical trials: Musculoskeletal Injuries
Subacromial Impingement Syndrome
High and Low Laser for Subacromial Impingement Syndrome
Shoulder pain is the third most common musculoskeletal problem after lumbar and neck diseases in clinical practice, and the most common cause of shoulder pain is subacromial impingement syndrome.
- Trial name
- NCT04784377
- Testing
- high intensity laser in addition to traditional physical therapy exercises, low level laser in addition to traditional physical therapy exercises, traditional physical therapy exercises
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Musculoskeletal, Fatigability
Influence of Core Training on Fatigue, Balance and Performance in Adolescent Football Players
Background: Adolescent football players are exposed to high physical and psychological demands due to intensive training, frequent matches, travel, and limited recovery time.
- Conditions
- Musculoskeletal, Fatigability, Core Muscle Weakness, Balance Changes
- Trial name
- NCT07560319
- Testing
- Core Training Group
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome
Do Simple Running Technique Changes Reduce Pain and Change Injury Causing Mechanics
This project aims to investigate whether an increase in step rate can be used to reduce pain and injury causing movement patterns in runners who are currently experiencing achilles tendonopathy, iliotibial band syndrome…
- Conditions
- Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome, Iliotibial Band Syndrome, Achilles Tendinopathy
- Trial name
- NCT03067545
- Testing
- Step rate increase
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Salford
Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Clinical Evaluation of Orion Lamina Cover in Patients Undergoing Lumbar Laminectomy With Instrumented Fusion
Laminectomy with internal fixation and osseofusion is a common surgery for treating degenerative spinal diseases. It removes excessive bone spurs and removes the lamina for decompression to relieve nerve compression, and then…
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis, Spinal Stenosis, Scoliosis
- Trial name
- NCT06532968
- Testing
- ORION spinal lamina cover
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Orion Biotech Inc.
Tennis Elbow
Comparison of Mulligan Technique and Muscle Energy Technique in Lateral Epicondylitis
In this study, the effects of mulligan and muscle energy techniques on pain, grip strength and functionality will be investigated in a randomized controlled manner in individuals with lateral epicondylitis.
- Trial name
- NCT04505215
- Testing
- Mulligan Technique, Muscle Energy Technique, Only Exercise (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- KTO Karatay University
Shoulder Impingement Syndrome
Electromyographic Activity of Posterior Oblique Sling Muscles in Patients With Shoulder Impingement Syndrome
this study aims to assess the gluteus maximus muscle electromyographic activity and the latissimus dorsi muscle electromyographic activity in patients with shoulder impingement syndrome , to improve the assessment procedure and…
- Trial name
- EMG (NCT06789991)
- Testing
- electromyography
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoporosis, Osteoporosis Fracture
The Effect of Semaglutide on Bone Health
Semaglutide has effects that include lowering blood sugar, reducing weight, and improving cardiovascular and renal outcomes, and it is now widely used in clinical practice.
- Conditions
- Osteoporosis, Osteoporosis Fracture, T2DM
- Trial name
- NCT07165158
- Testing
- semaglutide combined with metformin
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Bone Loss
Efficacy and Safety of Zoledronic Acid in Acute Spinal Cord Injury: Prevention of Bone Loss
This is a double-blind, randomized, placebo-controlled trial of zoledronic acid, 5mg, to be administered intravenously to people who have suffered an acute spinal cord fracture.
- Trial name
- NCT00844480
- Testing
- zoledronic acid
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Thomas J. Schnitzer
Orthopedic Disorder
Inpatient Enrollment of Patient Portal App
This study aims to determine if inpatient enrollment into a patient communication app improves clinic follow-up of orthopedic trauma patients and improves survey completion rates after orthopedic trauma.
- Trial name
- NCT03431259
- Testing
- Patient Gateway
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Massachusetts General Hospital
Spinal Cord Injuries, Spine Disease
Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial)
This randomized clinical trial will compare three groups of individuals with cervical/thoracic, complete or incomplete spinal cord injury (SCI) that will undergo: (i) early CPAP therapy in the management of moderate-to-severe…
- Trial name
- NCT05473689
- Testing
- Continuous positive airway pressure (CPAP) therapy
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University Health Network, Toronto
Spinal Cord Injuries, Muscle Spasticity
Cyproheptadine and Chlorpromazine Effects on Spasticity
The main goal of this research is to understand the neuronal mechanisms that mediate the development of spasticity and motor dysfunction after spinal cord injury.
- Trial name
- NCT01509885
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Trigger Points in Teres Major Muscle, Subacromial Impingement Syndrome
Teres Major Muscle and Subacromial Impingement Syndrome
There is not a clear understanding of the origin of symptoms perceived by patients with impingement of the soft tissue structures of the subacromial space.
- Trial name
- NCT02374125
- Testing
- Diacutaneous Fibrolysis, Trigger Point Pressure Release, Protocolized physiotherapy
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Knee Injuries, Anterior Cruciate Ligament Rupture
Stopping OsteoARthritis After an ACL Tear
By 2040, 25% of Canadians will have osteoarthritis, a disabling joint condition. Most people think osteoarthritis only affects older adults, but 50% of the 700,000 Canadian youth who hurt their knee playing sports annually will…
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Rupture, Osteoarthritis, Knee
- Trial name
- SOAR (NCT06195423)
- Testing
- Stop OsteoARthritis (SOAR) program, Living Well after ACLR program
- Where
- 2 sites in Canada
- Volunteers
- 210 people
- Sponsor
- University of British Columbia
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Skull Base Neoplasms, Cerebrospinal Fluid Leakage
Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery
The purpose of this study is to specifically evaluate the effectiveness of PuraGel, a RADA16 polypeptide hydrogel, in expediting post-operative healing and re-mucosalization of the nasoseptal flap harvest site during endoscopic…
- Conditions
- Skull Base Neoplasms, Cerebrospinal Fluid Leakage, Nasal; Hypertrophy, Mucous Membrane (Septum)
- Trial name
- NCT05898074
- Testing
- Non-Absorbable Packing (Silastic Splint), PuraGel (RADA16) Hydrogel
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Tennis Elbow, Musculoskeletal Diseases
Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia
This randomised controlled trial will evaluate the role of manual therapy and therapeutic exercise and corticosteroid injections in the treatment of lateral epicondylalgia (tennis elbow).
- Trial name
- NCT00110318
- Testing
- Manual therapy and therapeutic exercise, Corticosteroid injections
- Where
- Australia
- Volunteers
- 198 people
- Sponsor
- The University of Queensland
Rhabdomyolysis, Renal Failure
Myoglobin Removal by High Cut-off CVVHD
A high cut-off dialyzer (septeX) is tested for the removal of myoglobin which is not efficiently removed by standard high flux dialysis membranes.
- Trial name
- HicoRhabdo (NCT01467180)
- Testing
- septeX, HF CVVH
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Vantive Health LLC
Tendinosis
Efficacy of Maitland Mobilization in Shoulder Pathology
The shoulder is a mobile structure which generates a lot of pathologies. One of them is rotator cuff tendinosis. On the other hand, it has been investigated that Maitland is effective for reducing pain and for mobility in the…
- Trial name
- NCT05030402
- Testing
- Maitland, Tens, exercise, SW, Conventional physiotherapy
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- University of Las Palmas de Gran Canaria
Keratoconus, Ocular Surface Disease
Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting
EYEdeal Scanning Technology enables rapid measurement of corneal and scleral topography. By accurately measuring the ocular surface with this imaging technology, the current iterative fitting method required to fit PROSE…
- Conditions
- Keratoconus, Ocular Surface Disease, Pellucid Marginal Corneal Degeneration, Ectasia
- Trial name
- NCT04649177
- Testing
- Ocular surface optical coherence tomography
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Boston Sight
Supraspinatus Tendinitis
Effect of Kinesotaping on Management of Supraspinatus Tendinitis
Supraspinatus tendonitis is a common clinical problem that causes functional and labor disabilities. It is the most frequent cause of shoulder pain.
- Trial name
- NCT03744195
- Testing
- Group I Experimental Kinesotaping, Group II conventional training group
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
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